Strain Name:
C57BL/6J-MtgxR5970Btlr
Stock Number:
044153-MU
Citation ID:
RRID:MMRRC_044153-MU
Other Names:
R5970 (G1)
Major Collection:

Gene Information

Aldh1l1
Name: aldehyde dehydrogenase 1 family, member L1
Synonyms: 1810048F20Rik, Fthfd
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 107747
HGNC: HGNC:3978
Homologene: 122031
Kcns2
Name: K+ voltage-gated channel, subfamily S, 2
Synonyms: E130006J24Rik, Kv9.2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 16539
VEGA: 15
HGNC: HGNC:6301
Homologene: 22465
Scn3a
Name: sodium channel, voltage-gated, type III, alpha
Synonyms: Nav1.3, LOC381367
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 20269
Homologene: 56005
Tfdp2
Name: transcription factor Dp 2
Synonyms: DP3, DP-3, A330080J22Rik, 1110029I05Rik, DP3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 211586
Homologene: 4578
Spidr
Name: scaffolding protein involved in DNA repair
Synonyms: 2310008H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224008
VEGA: 16
Homologene: 51693
Sdf2
Name: stromal cell derived factor 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20316
Homologene: 5045
Dnmbp
Name: dynamin binding protein
Synonyms: 2410003M15Rik, Tuba, 2410003L07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 71972
Homologene: 9061
Ywhah
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Synonyms: 14-3-3 eta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 22629
Homologene: 37767
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, Zcwcc3, 1110051N18Rik, D16Jhu32e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 338467
Homologene: 32257
St13
Name: suppression of tumorigenicity 13
Synonyms: 3110002K08Rik, 1110007I03Rik, PRO0786, HSPABP1, SNC6, p48, Hsp70 interacting protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 70356
Homologene: 2921
Birc6
Name: baculoviral IAP repeat-containing 6
Synonyms: Bruce, A430040A19Rik, apollon, A430032G04Rik, D630005A10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 12211
Homologene: 7248
Mical3
Name: microtubule associated monooxygenase, calponin and LIM domain containing 3
Synonyms: MICAL-3, C130040D16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194401
Homologene: 85288
Dennd4c
Name: DENN/MADD domain containing 4C
Synonyms: 1700065A05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329877
Homologene: 23057
Amotl1
Name: angiomotin-like 1
Synonyms: 2310067L22Rik, 2310010G08Rik, 4932416D09Rik, JEAP
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 75723
Homologene: 43977
Kdm3b
Name: KDM3B lysine (K)-specific demethylase 3B
Synonyms: 5830462I21Rik, JHDM2B, Jmjd1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 277250
VEGA: 18
HGNC: HGNC:1337
Homologene: 41145
Ambn
Name: ameloblastin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 11698
HGNC: HGNC:452
Homologene: 7625
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, 2300002E22Rik, DP, rul
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Cecr2
Name: CECR2, histone acetyl-lysine reader
Synonyms: 2610101O16Rik, 2810409N01Rik, cat eye syndrome chromosome region, candidate 2, Gtl4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 330409
HGNC: HGNC:1840
Homologene: 64662
Man2a1
Name: mannosidase 2, alpha 1
Synonyms: Map-2, Mana2, Mana-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 17158
HGNC: HGNC:6824
Homologene: 1777
Nipbl
Name: NIPBL cohesin loading factor
Synonyms: 4933421G18Rik, 4921518A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 71175
VEGA: 15
Homologene: 15850
Heatr6
Name: HEAT repeat containing 6
Synonyms: 2700008B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217026
Homologene: 11116
Col4a3
Name: collagen, type IV, alpha 3
Synonyms: tumstatin, alpha3(IV)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12828
HGNC: HGNC:2204
Homologene: 68033
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Dnah10
Name: dynein, axonemal, heavy chain 10
Synonyms: Dnahc10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 56087
HGNC: HGNC:2941
Homologene: 25816
Stradb
Name: STE20-related kinase adaptor beta
Synonyms: D1Ucla2, PRO1038, Als2cr2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 227154
Homologene: 10237
Olfr835
Name: olfactory receptor 835
Synonyms: MOR150-3, GA_x6K02T2PVTD-12771995-12772930
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 257872
Homologene: 133702
Efr3b
Name: EFR3 homolog B
Synonyms: C030014M07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 668212
VEGA: 12
Homologene: 66195
Ccser1
Name: coiled-coil serine rich 1
Synonyms: Fam190a, 6230405M12Rik, C130092O11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 232035
Homologene: 28086
Tcp11l2
Name: t-complex 11 (mouse) like 2
Synonyms: E430026E19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 216198
Homologene: 17129
Pcdhb5
Name: protocadherin beta 5
Synonyms: PcdhbE, Pcdhb4A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 93876
HGNC: HGNC:8689
Homologene: 75103
Rp1
Name: retinitis pigmentosa 1 (human)
Synonyms: Dcdc3, Rp1h, oxygen-regulated protein 1, mG145, Orp1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 19888
Homologene: 4564
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, MUC9, 2300002I04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Duox1
Name: dual oxidase 1
Synonyms: NOXEF1, THOX1, LNOX1, 9930101G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 99439
HGNC: HGNC:3062
Homologene: 68136
Mprip
Name: myosin phosphatase Rho interacting protein
Synonyms: Rhoip3, Gm34094, RIP3, p116Rip, p116 Rho interacting protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 26936
Homologene: 9034
Mroh1
Name: maestro heat-like repeat family member 1
Synonyms: Heatr7a, D330001F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223658
Homologene: 44882
Col6a5
Name: collagen, type VI, alpha 5
Synonyms: Gm7455, Col6a5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 665033
Homologene: 122792
Vmn2r104
Name: vomeronasal 2, receptor 104
Synonyms: V2r7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 22313
Homologene: 129751
Pigp
Name: phosphatidylinositol glycan anchor biosynthesis, class P
Synonyms: Dcrc, Dscr5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 56176
HGNC: HGNC:3046
Homologene: 32444
Mybpc1
Name: myosin binding protein C, slow-type
Synonyms: Slow-type C-protein, 8030451F13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 109272
HGNC: HGNC:7549
Homologene: 1846
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: 2900009M21Rik, C130039D01Rik, 2010013M14Rik, CYLD1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Cfap52
Name: cilia and flagella associated protein 52
Synonyms: Wdr16, 4933417B11Rik, 1700019F09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71860
Homologene: 12416
Tmprss15
Name: transmembrane protease, serine 15
Synonyms: enteropeptidase, enterokinase, A130097D21Rik, Prss7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 19146
HGNC: HGNC:9490
Homologene: 2075
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 329942
Homologene: 89034
Dnaic1
Name: dynein, axonemal, intermediate chain 1
Synonyms: 1110066F04Rik, b2b1526Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 68922
HGNC: HGNC:2954
Homologene: 8122
Mypn
Name: myopalladin
Synonyms: 1110056A04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 68802
VEGA: 10
Homologene: 23778
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 622434
Homologene: 9204
Serpina3b
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3B
Synonyms: 6A1, antitrypsin, alpha-1 antiproteinase, A030003A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 271047
HGNC: HGNC:16
Homologene: 120222
St8sia4
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
Synonyms: PST-1, ST8SiaIV, Siat8d, PST
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 20452
Homologene: 4147
Cry2
Name: cryptochrome 2 (photolyase-like)
Synonyms: D130054K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12953
HGNC: HGNC:2385
Homologene: 56466
Snx31
Name: sorting nexin 31
Synonyms: 4631426E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 66696
Homologene: 23551
Zfp324
Name: zinc finger protein 324
Synonyms: ZF5128, D430030K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243834
Homologene: 8648
Gpt
Name: glutamic pyruvic transaminase, soluble
Synonyms: 2310022B03Rik, 1300007J06Rik, ALT, Gpt-1, Gpt1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76282
VEGA: 15
HGNC: HGNC:4552
Homologene: 134231
Trav10d
Name: T cell receptor alpha variable 10D
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 100101486
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 4,348,462 bp
  • T to C, chromosome 1 at 58,980,016 bp
  • A to G, chromosome 1 at 82,716,329 bp
  • A to G, chromosome 1 at 95,653,582 bp
  • T to A, chromosome 2 at 65,494,781 bp
  • A to G, chromosome 2 at 92,412,967 bp
  • T to A, chromosome 2 at 122,340,201 bp
  • T to C, chromosome 3 at 62,340,047 bp
  • A to G, chromosome 4 at 41,625,281 bp
  • G to A, chromosome 4 at 86,825,512 bp
  • G to C, chromosome 4 at 128,546,151 bp
  • T to A, chromosome 5 at 33,026,948 bp
  • T to C, chromosome 5 at 88,467,951 bp
  • T to C, chromosome 5 at 124,808,729 bp
  • T to A, chromosome 6 at 61,311,242 bp
  • G to A, chromosome 6 at 90,597,046 bp
  • A to G, chromosome 6 at 120,720,907 bp
  • G to A, chromosome 6 at 120,958,271 bp
  • C to A, chromosome 7 at 12,969,366 bp
  • C to T, chromosome 7 at 141,790,669 bp
  • A to T, chromosome 7 at 141,856,712 bp
  • G to T, chromosome 8 at 88,732,993 bp
  • T to A, chromosome 9 at 14,596,528 bp
  • A to G, chromosome 9 at 19,035,147 bp
  • C to T, chromosome 9 at 96,317,574 bp
  • T to A, chromosome 9 at 105,945,847 bp
  • A to G, chromosome 10 at 63,131,023 bp
  • T to A, chromosome 10 at 84,594,797 bp
  • A to G, chromosome 10 at 88,542,456 bp
  • A to T, chromosome 11 at 59,757,721 bp
  • A to G, chromosome 11 at 67,930,744 bp
  • A to T, chromosome 11 at 78,246,080 bp
  • G to A, chromosome 11 at 83,753,718 bp
  • T to A, chromosome 12 at 3,968,590 bp
  • T to G, chromosome 12 at 104,134,091 bp
  • T to C, chromosome 13 at 38,195,702 bp
  • T to C, chromosome 14 at 52,811,322 bp
  • T to C, chromosome 15 at 8,296,818 bp
  • A to G, chromosome 15 at 34,839,784 bp
  • A to T, chromosome 15 at 36,523,488 bp
  • G to A, chromosome 15 at 76,451,491 bp
  • A to G, chromosome 15 at 76,699,352 bp
  • A to T, chromosome 15 at 81,377,798 bp
  • A to C, chromosome 16 at 16,114,869 bp
  • C to T, chromosome 16 at 79,057,659 bp
  • C to T, chromosome 16 at 93,866,453 bp
  • T to A, chromosome 16 at 94,370,194 bp
  • A to G, chromosome 17 at 20,029,471 bp
  • A to G, chromosome 17 at 64,625,380 bp
  • G to T, chromosome 17 at 74,618,502 bp
  • A to G, chromosome 18 at 34,829,289 bp
  • T to A, chromosome 18 at 37,321,773 bp
  • T to A, chromosome 19 at 43,854,171 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5970 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044153-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.