Strain Name:
C57BL/6J-MtgxR5989Btlr
Stock Number:
044169-MU
Citation ID:
RRID:MMRRC_044169-MU
Other Names:
R5989 (G1)
Major Collection:

Gene Information

Nmral1
Name: NmrA-like family domain containing 1
Synonyms: 1110025F24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 67824
Homologene: 41388
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Zbtb21
Name: zinc finger and BTB domain containing 21
Synonyms: B430213I24Rik, Znf295, Zfp295, 5430437K12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 114565
VEGA: 16
Homologene: 10799
Rnd2
Name: Rho family GTPase 2
Synonyms: Rohn, Arhn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 11858
Homologene: 21123
Nefm
Name: neurofilament, medium polypeptide
Synonyms: Nef3, NF165, NF-M, NF160, Nfm, neurofilament-M
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18040
HGNC: HGNC:7734
Homologene: 137211
Cartpt
Name: CART prepropeptide
Synonyms: Cart
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 27220
VEGA: 13
Homologene: 3169
Dmrt1
Name: doublesex and mab-3 related transcription factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 50796
HGNC: HGNC:2934
Homologene: 9280
Vps51
Name: VPS51 GARP complex subunit
Synonyms: 3110057M17Rik, 1110014N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 68505
HGNC: HGNC:1172
Homologene: 34675
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: Trrp7, 9830168K16Rik, TRPC7, LTRPC2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 28240
Homologene: 20709
Ebf1
Name: early B cell factor 1
Synonyms: O/E-1, Olf1, Olf-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13591
HGNC: HGNC:3126
Homologene: 7297
Prkag3
Name: protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Synonyms: AMPKg3, AMPKg3L, AMPKg3S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 241113
HGNC: HGNC:9387
Homologene: 23006
Ipcef1
Name: interaction protein for cytohesin exchange factors 1
Synonyms: A130090K04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 320495
Homologene: 32271
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Slc17a3
Name: solute carrier family 17 (sodium phosphate), member 3
Synonyms: Npt4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105355
Homologene: 21319
Spem1
Name: sperm maturation 1
Synonyms: 1700095G12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 74288
Homologene: 45717
Olfr191
Name: olfactory receptor 191
Synonyms: GA_x54KRFPKG5P-55314632-55313703, MOR183-5P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 258035
Homologene: 128162
Lcp1
Name: lymphocyte cytosolic protein 1
Synonyms: L-plastin, Pls2, D14Ertd310e, L-fimbrin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 18826
HGNC: HGNC:6528
Homologene: 80174
Cyp2c40
Name: cytochrome P450, family 2, subfamily c, polypeptide 40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 13099
Homologene: 74936
Mtif2
Name: mitochondrial translational initiation factor 2
Synonyms: IF-2mt, 2410112O06Rik, 2310038D14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 76784
HGNC: HGNC:7441
Homologene: 1840
Prrxl1
Name: paired related homeobox protein-like 1
Synonyms: Drg11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 107751
Panx2
Name: pannexin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 406218
HGNC: HGNC:8600
Homologene: 14155
Sfta2
Name: surfactant associated 2
Synonyms: EG433102
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 433102
Gm10271
Name: predicted gene 10271
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Ggnbp1
Name: gametogenetin binding protein 1
Synonyms: 0610031G08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 70772
Homologene: 79568
Gm10767
Name: predicted gene 10767
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 100038538
Tmem200c
Name: transmembrane protein 200C
Synonyms: Gm6338
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 622645
VEGA: 17
Homologene: 78765
Gm42417
Name: predicted gene, 42417
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 36,532,192 bp
  • T to C, chromosome 1 at 74,741,274 bp
  • A to T, chromosome 10 at 6,979,532 bp
  • A to G, chromosome 10 at 77,959,900 bp
  • A to T, chromosome 10 at 116,972,592 bp
  • A to G, chromosome 11 at 29,530,098 bp
  • G to T, chromosome 11 at 44,996,171 bp
  • G to A, chromosome 11 at 69,821,125 bp
  • C to T, chromosome 11 at 101,468,999 bp
  • A to G, chromosome 13 at 23,842,428 bp
  • G to A, chromosome 13 at 66,907,986 bp
  • T to A, chromosome 13 at 99,898,984 bp
  • A to G, chromosome 14 at 32,608,188 bp
  • A to G, chromosome 14 at 68,124,329 bp
  • A to T, chromosome 14 at 75,199,387 bp
  • G to A, chromosome 15 at 47,590,764 bp
  • T to C, chromosome 15 at 89,060,252 bp
  • G to A, chromosome 16 at 4,719,038 bp
  • A to T, chromosome 16 at 59,086,334 bp
  • G to A, chromosome 16 at 97,951,499 bp
  • A to G, chromosome 17 at 27,029,747 bp
  • G to T, chromosome 17 at 35,649,780 bp
  • G to T, chromosome 17 at 68,837,436 bp
  • G to A, chromosome 18 at 88,973,626 bp
  • A to G, chromosome 19 at 6,076,372 bp
  • T to A, chromosome 19 at 25,545,881 bp
  • T to C, chromosome 19 at 39,807,580 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5989 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044169-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.