Strain Name:
C57BL/6J-MtgxR6106Btlr
Stock Number:
044256-MU
Citation ID:
RRID:MMRRC_044256-MU
Other Names:
R6106 (G1)
Major Collection:

Gene Information

Tln2
Name: talin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 70549
VEGA: 9
Homologene: 56692
Cdon
Name: cell adhesion molecule-related/down-regulated by oncogenes
Synonyms: CDO, CAM-related/down-regulated by oncogenes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 57810
Homologene: 22996
Apoa5
Name: apolipoprotein A-V
Synonyms: RAP3, Apoav, 1300007O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 66113
Homologene: 14197
Gstcd
Name: glutathione S-transferase, C-terminal domain containing
Synonyms: 4933434L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 67553
Homologene: 11693
Cnot8
Name: CCR4-NOT transcription complex, subunit 8
Synonyms: 1500015I04Rik, 1810022F04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69125
HGNC: HGNC:9207
Homologene: 48304
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 70227
Homologene: 133818
Snx32
Name: sorting nexin 32
Synonyms: B930037P14Rik, Snx6b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 225861
VEGA: 19
Homologene: 62637
Ccdc80
Name: coiled-coil domain containing 80
Synonyms: DRO1, 2610001E17Rik, Ssg1, Urb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 67896
Homologene: 12206
Fam193a
Name: family with sequence homology 193, member A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231128
Homologene: 2746
Adgrl4
Name: adhesion G protein-coupled receptor L4
Synonyms: 1110033N21Rik, EGF-TM7 receptor, Etl, Eltd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 170757
Homologene: 11170
Slc16a1
Name: solute carrier family 16 (monocarboxylic acid transporters), member 1
Synonyms: MCT1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 20501
Homologene: 20662
Zfhx2
Name: zinc finger homeobox 2
Synonyms: zfh-5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239102
Homologene: 52657
Pcdhb11
Name: protocadherin beta 11
Synonyms: Pcdhb5E, PcdhbK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 93882
Homologene: 62178
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 269023
VEGA: 18
Homologene: 18485
Clspn
Name: claspin
Synonyms: E130314M08Rik, C85083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 269582
Homologene: 11138
Wdr24
Name: WD repeat domain 24
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 268933
Homologene: 6870
Stc2
Name: stanniocalcin 2
Synonyms: mustc2, Stc2l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20856
Homologene: 2753
2010300C02Rik
Name: RIKEN cDNA 2010300C02 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72097
Homologene: 19208
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Morn3
Name: MORN repeat containing 3
Synonyms: 4930438O03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74890
Homologene: 42069
Olfr169
Name: olfactory receptor 169
Synonyms: MOR273-3P, GA_x54KRFPKG5P-16014972-16014031
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 258158
Homologene: 128058
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 628444
Homologene: 129683
Olfr632
Name: olfactory receptor 632
Synonyms: MOR2-1, GA_x6K02T2PBJ9-6671256-6672209
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 259123
Homologene: 64963
Vmn2r9
Name: vomeronasal 2, receptor 9
Synonyms: EG435864
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 435864
Homologene: 129606
Slc19a1
Name: solute carrier family 19 (folate transporter), member 1
Synonyms: reduced folate carrier, RFC1, RFC-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 20509
Homologene: 57139
Usp43
Name: ubiquitin specific peptidase 43
Synonyms: C630032K07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216835
Homologene: 129879
Nrd1
Name: nardilysin, N-arginine dibasic convertase, NRD convertase 1
Synonyms: NRD-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 230598
HGNC: HGNC:7995
Homologene: 68260
Galnt1
Name: polypeptide N-acetylgalactosaminyltransferase 1
Synonyms: ppGaNTase-T1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 14423
HGNC: HGNC:4123
Homologene: 8469
Ccdc158
Name: coiled-coil domain containing 158
Synonyms: 4932413O14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 320696
Homologene: 18560
Gm14139
Name: predicted gene 14139
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 100271882
Homologene: 134546
Pfpl
Name: pore forming protein-like
Synonyms: Epcs5, Epcs50
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 56093
VEGA: 19
Homologene: 130704
Phyhip
Name: phytanoyl-CoA hydroxylase interacting protein
Synonyms: PAHX-AP1, C630010D02Rik, PAHX-AP#1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105653
Homologene: 8847
Plch1
Name: phospholipase C, eta 1
Synonyms: Plcl3, PLCeta1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 269437
Homologene: 88833
Calhm2
Name: calcium homeostasis modulator family member 2
Synonyms: 2810048G17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72691
Homologene: 9303
Psg16
Name: pregnancy specific glycoprotein 16
Synonyms: bCEA, Cea11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 26436
Ace
Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Synonyms: CD143
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Bfsp2
Name: beaded filament structural protein 2, phakinin
Synonyms: CP49
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 107993
HGNC: HGNC:1041
Homologene: 20791
Setdb2
Name: SET domain, bifurcated 2
Synonyms: KMT1F, LOC239122
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239122
Homologene: 12903
Sorbs3
Name: sorbin and SH3 domain containing 3
Synonyms: SH3P3, Sh3d4, vinexin alpha, vinexin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 20410
VEGA: 14
Homologene: 4218
Tomm34
Name: translocase of outer mitochondrial membrane 34
Synonyms: 2610100K07Rik, TOM34
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67145
Homologene: 4956
Olfr883
Name: olfactory receptor 883
Synonyms: MOR162-6, GA_x6K02T2PVTD-31705144-31706073
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258414
Homologene: 86689
Sgms1
Name: sphingomyelin synthase 1
Synonyms: SMS1alpha2, 9530058O11Rik, SMS1, Tmem23, SMS1beta, SMS1alpha1, SMS1gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 208449
Homologene: 27040
Fam183b
Name: family with sequence similarity 183, member B
Synonyms: 3100002J23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75429
Homologene: 28543
Pigu
Name: phosphatidylinositol glycan anchor biosynthesis, class U
Synonyms: Cdc91l1, 5430426F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228812
Homologene: 6553
Cept1
Name: choline/ethanolaminephosphotransferase 1
Synonyms: 9930118K05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 99712
Homologene: 81624
Olfr913
Name: olfactory receptor 913
Synonyms: MOR165-9P, MOR165-10, GA_x6K02T2PVTD-32296575-32297513
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 258225
VEGA: 9
Homologene: 79398
Ighv1-42
Name: immunoglobulin heavy variable V1-42
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 629906
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 37,613,412 bp
  • A to G, chromosome 2 at 150,192,805 bp
  • A to T, chromosome 2 at 155,297,196 bp
  • A to G, chromosome 2 at 164,060,991 bp
  • C to T, chromosome 3 at 63,702,023 bp
  • T to C, chromosome 3 at 104,652,994 bp
  • A to T, chromosome 3 at 106,503,676 bp
  • C to A, chromosome 3 at 132,998,914 bp
  • A to G, chromosome 3 at 151,540,985 bp
  • A to T, chromosome 4 at 109,044,585 bp
  • T to A, chromosome 4 at 126,590,641 bp
  • A to T, chromosome 5 at 34,459,030 bp
  • T to C, chromosome 5 at 92,627,466 bp
  • C to T, chromosome 5 at 108,845,036 bp
  • A to G, chromosome 5 at 123,046,760 bp
  • T to A, chromosome 7 at 17,095,166 bp
  • T to C, chromosome 7 at 39,535,134 bp
  • T to A, chromosome 7 at 42,012,325 bp
  • A to G, chromosome 7 at 103,938,193 bp
  • T to A, chromosome 9 at 35,455,408 bp
  • T to A, chromosome 9 at 38,026,466 bp
  • T to C, chromosome 9 at 38,594,956 bp
  • A to T, chromosome 9 at 46,270,633 bp
  • C to T, chromosome 9 at 67,323,020 bp
  • T to A, chromosome 9 at 103,479,824 bp
  • T to A, chromosome 10 at 77,044,769 bp
  • T to A, chromosome 11 at 31,360,392 bp
  • T to C, chromosome 11 at 58,113,990 bp
  • T to C, chromosome 11 at 58,796,601 bp
  • A to G, chromosome 11 at 67,879,907 bp
  • A to G, chromosome 11 at 105,989,012 bp
  • A to C, chromosome 12 at 114,937,287 bp
  • T to A, chromosome 14 at 55,068,310 bp
  • T to A, chromosome 14 at 59,423,449 bp
  • T to C, chromosome 14 at 70,192,604 bp
  • T to C, chromosome 14 at 70,461,859 bp
  • T to C, chromosome 15 at 55,520,008 bp
  • A to G, chromosome 16 at 19,566,259 bp
  • T to C, chromosome 16 at 45,096,710 bp
  • C to T, chromosome 17 at 25,824,605 bp
  • G to A, chromosome 18 at 24,254,663 bp
  • A to G, chromosome 18 at 37,423,003 bp
  • G to T, chromosome 18 at 54,987,872 bp
  • A to G, chromosome 19 at 5,498,014 bp
  • G to T, chromosome 19 at 12,429,461 bp
  • A to G, chromosome 19 at 32,124,425 bp
  • A to T, chromosome 19 at 47,133,062 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6106 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
044256-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.