Strain Name:
C57BL/6J-MtgxR6679Btlr/Mmmh
Stock Number:
044798-MU
Citation ID:
RRID:MMRRC_044798-MU
Other Names:
R6679 (G1)
Major Collection:

Strain Information

Arhgef7
Name: Rho guanine nucleotide exchange factor
Synonyms: PIX, betaPix-b, betaPix, Pak interacting exchange factor, p85SPR, betaPix-c, Cool, cool-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 54126
Homologene: 2895
Sash1
Name: SAM and SH3 domain containing 1
Synonyms: 2500002E12Rik, A330076K04Rik, 1100001C18Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 70097
Homologene: 69182
Zfp523
Name: zinc finger protein 523
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224656
Homologene: 2569
Rsf1
Name: remodeling and spacing factor 1
Synonyms: Hbxap, p325, XAP8, C030033M12Rik, 4832420A03Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Rag1
Name: recombination activating 1
Synonyms: Rag-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19373
HGNC: HGNC:9831
Homologene: 387
Htr1a
Name: 5-hydroxytryptamine (serotonin) receptor 1A
Synonyms: 5-HT1A receptor, Gpcr18
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15550
VEGA: 13
HGNC: HGNC:5286
Homologene: 20148
Sh3glb2
Name: SH3-domain GRB2-like endophilin B2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227700
Homologene: 10595
Rxfp3
Name: relaxin family peptide receptor 3
Synonyms: Rln3r1, Salpr
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239336
Homologene: 9568
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
Fgfrl1
Name: fibroblast growth factor receptor-like 1
Synonyms: FGFR5gamma, FGFR5beta, FGFR5, fibroblast growth factor receptor 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 116701
HGNC: HGNC:3693
Homologene: 11067
Ston2
Name: stonin 2
Synonyms: 4933401N24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 108800
Homologene: 84338
Ift43
Name: intraflagellar transport 43
Synonyms: 1700019E19Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76411
VEGA: 12
Homologene: 12641
Usp33
Name: ubiquitin specific peptidase 33
Synonyms: 9830169D19Rik, Vdu1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 170822
Homologene: 8996
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Peg10
Name: paternally expressed 10
Synonyms: HB-1, Edr, MyEF-3 like, MEF3L, Mart2, Rtl2, MyEF-3, Mar2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 170676
Homologene: 116067
Efcab2
Name: EF-hand calcium binding domain 2
Synonyms: 1700073K01Rik, D830011E08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68226
Homologene: 12248
Fat2
Name: FAT atypical cadherin 2
Synonyms: EMI2, mKIAA0811, LOC245827, Fath2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Col5a3
Name: collagen, type V, alpha 3
Synonyms: Pro-alpha3(V)
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 53867
Homologene: 9253
Adgrb3
Name: adhesion G protein-coupled receptor B3
Synonyms: Bai3, A830096D10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210933
HGNC: HGNC:945
Homologene: 1289
Dock10
Name: dedicator of cytokinesis 10
Synonyms: A630054M16Rik, Zizimin3, Jr5, Jr4, ZIZ3, 9330153B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210293
Homologene: 45952
Ahnak2
Name: AHNAK nucleoprotein 2
Synonyms: LOC382643
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 100041194
Homologene: 131081
Gm10801
Name: predicted gene 10801
Type: Gene
Species: Mouse
Chromosome: 2
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: LOC100042382, Gm3812, Liprin-alpha4, 1110008G13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Jakmip2
Name: janus kinase and microtubule interacting protein 2
Synonyms: 6430702L21Rik, D930046L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 76217
VEGA: 18
Homologene: 8866
Sycp2
Name: synaptonemal complex protein 2
Synonyms: 3830402K23Rik, 4930518F03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320558
Homologene: 8604
Myo1c
Name: myosin IC
Synonyms: mm1beta, C80397, myr2, myosin-Ibeta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Tlr11
Name: toll-like receptor 11
Synonyms: LOC239081
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239081
Homologene: 77905
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Nme8
Name: NME/NM23 family member 8
Synonyms: 1700056P15Rik, Txndc3, Sptrx-2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73412
Homologene: 9593
Hdac3
Name: histone deacetylase 3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15183
HGNC: HGNC:4854
Homologene: 48250
Syt10
Name: synaptotagmin X
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54526
Homologene: 10303
Or5h26
Name: olfactory receptor family 5 subfamily H member 26
Synonyms: MOR183-1, GA_x54KRFPKG5P-55389051-55388122, Olfr196
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258775
Homologene: 74113
Creb5
Name: cAMP responsive element binding protein 5
Synonyms: 9430076C15Rik, D430026C09Rik, Crebpa
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 231991
Homologene: 18215
Aoc3
Name: amine oxidase, copper containing 3
Synonyms: VAP1, semicarbazide-sensitive amine oxidase, SSAO
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11754
HGNC: HGNC:550
Homologene: 2770
Rbm24
Name: RNA binding motif protein 24
Synonyms: 6330546B05Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 666794
VEGA: 13
Homologene: 23015
Erich3
Name: glutamate rich 3
Synonyms: 5031409G23Rik, 4922501L14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 209601
Homologene: 27877
Vmn1r123
Name: vomeronasal 1 receptor 123
Synonyms: Gm1446, LOC384695
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384695
Homologene: 104166
Tcfl5
Name: transcription factor-like 5 (basic helix-loop-helix)
Synonyms: FIG beta, Figlb
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277353
Homologene: 4814
Ehd1
Name: EH-domain containing 1
Synonyms: RME-1, Past1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13660
HGNC: HGNC:3242
Homologene: 81678
Wdr55
Name: WD repeat domain 55
Synonyms: 2410080P20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 67936
VEGA: 18
Homologene: 9789
Gm10770
Name: predicted gene 10770
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 544945
VEGA: 2
4930449I24Rik
Name: RIKEN cDNA 4930449I24 gene
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67410
Homologene: 86127
Dnase1l1
Name: deoxyribonuclease 1-like 1
Synonyms: Dnl1ll, G4.8, Dnase1ll, 2310005K03Rik
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 69537
HGNC: HGNC:2957
Homologene: 4896
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 25,131,296 bp
  • A to G, chromosome 1 at 80,566,797 bp
  • A to T, chromosome 1 at 134,309,679 bp
  • G to A, chromosome 1 at 178,437,404 bp
  • G to A, chromosome 2 at 30,350,619 bp
  • TC to TCGGC, chromosome 2 at 98,663,806 bp
  • G to A, chromosome 2 at 101,644,284 bp
  • G to A, chromosome 2 at 150,179,649 bp
  • A to G, chromosome 2 at 178,380,928 bp
  • G to T, chromosome 2 at 180,635,262 bp
  • A to G, chromosome 3 at 114,152,719 bp
  • T to A, chromosome 3 at 152,368,487 bp
  • T to A, chromosome 3 at 154,762,429 bp
  • T to A, chromosome 5 at 41,816,666 bp
  • G to A, chromosome 5 at 108,704,972 bp
  • G to T, chromosome 5 at 108,704,973 bp
  • T to A, chromosome 5 at 146,504,940 bp
  • CCAACAACAACAACAACAACAACA to CCAACAACAACAACAACAACA, chromosome 6 at 4,754,276 bp
  • G to T, chromosome 6 at 53,685,469 bp
  • T to A, chromosome 7 at 21,162,943 bp
  • A to AAGGCGACGG, chromosome 7 at 97,579,904 bp
  • T to A, chromosome 8 at 11,824,667 bp
  • C to T, chromosome 9 at 20,779,033 bp
  • T to A, chromosome 10 at 8,740,185 bp
  • A to T, chromosome 11 at 55,309,305 bp
  • C to T, chromosome 11 at 75,671,635 bp
  • T to A, chromosome 11 at 101,331,453 bp
  • A to G, chromosome 12 at 86,138,818 bp
  • G to T, chromosome 12 at 91,648,096 bp
  • G to A, chromosome 12 at 112,772,976 bp
  • A to T, chromosome 13 at 19,690,970 bp
  • A to T, chromosome 13 at 46,418,992 bp
  • A to G, chromosome 13 at 105,445,428 bp
  • T to C, chromosome 14 at 50,362,854 bp
  • T to C, chromosome 15 at 11,035,870 bp
  • A to G, chromosome 15 at 76,173,815 bp
  • C to A, chromosome 15 at 89,814,371 bp
  • A to G, chromosome 16 at 59,167,846 bp
  • C to T, chromosome 17 at 28,202,220 bp
  • T to C, chromosome 18 at 34,487,022 bp
  • G to A, chromosome 18 at 36,763,124 bp
  • A to G, chromosome 18 at 37,944,933 bp
  • T to C, chromosome 18 at 43,565,949 bp
  • A to G, chromosome 19 at 6,294,444 bp
  • C to T, chromosome X at 74,277,038 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6679 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044798-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.