Strain Name:
C57BL/6J-MtgxR6713Btlr/Mmmh
Stock Number:
044831-MU
Citation ID:
RRID:MMRRC_044831-MU
Other Names:
R6713 (G1)
Major Collection:

Strain Information

St8sia1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Synonyms: GD3 synthase, ST8Sia I, alpha-2,8-sialyltransferase, Siat8, Siat8a, 9330109E03Rik, GD3S
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20449
Homologene: 2282
Pax2
Name: paired box 2
Synonyms: Pax-2, Opdc
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18504
HGNC: HGNC:8616
Homologene: 2968
Pias2
Name: protein inhibitor of activated STAT 2
Synonyms: Dib, 6330408K17Rik, ARIP3, PIASxbeta, PIASxalpha, PIASxb, Miz1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17344
VEGA: 18
Homologene: 20979
Supt20
Name: SPT20 SAGA complex component
Synonyms: D3Ertd300e, p38IP, p38 interacting protein, Fam48a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56790
Homologene: 134155
Kpna6
Name: karyopherin subunit alpha 6
Synonyms: IPOA7, NPI-2, importin alpha 7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16650
HGNC: HGNC:6399
Homologene: 22472
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70227
Homologene: 133818
Otud6b
Name: OTU domain containing 6B
Synonyms: 2600013N14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72201
Homologene: 6064
Fan1
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: 6030441H18Rik, Mtmr15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330554
Homologene: 45598
Cemip
Name: cell migration inducing protein, hyaluronan binding
Synonyms: 12H19.01.T7, 6330404C01Rik, 9930013L23Rik, Hybid
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80982
Homologene: 10268
Lrrc40
Name: leucine rich repeat containing 40
Synonyms: 2610040E16Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67144
Homologene: 9825
Lins1
Name: lines homolog 1
Synonyms: 2700083B01Rik, Wins2, Lins
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72635
Homologene: 10034
Ssh2
Name: slingshot protein phosphatase 2
Synonyms: SSH-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237860
Homologene: 14116
Srcap
Name: Snf2-related CREBBP activator protein
Synonyms: D030022P06Rik, F630004O05Rik, B930091H02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043597
Homologene: 38213
Smarcc2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Synonyms: 5930405J04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68094
VEGA: 10
Homologene: 2312
Or5ak24
Name: olfactory receptor family 5 subfamily AK member 24
Synonyms: GA_x6K02T2Q125-46907515-46906571, MOR203-4, Olfr994
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258425
Homologene: 17245
Cdh16
Name: cadherin 16
Synonyms: KSP-cadherin
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12556
HGNC: HGNC:1755
Homologene: 2997
F3
Name: coagulation factor III
Synonyms: tissue factor, TF, Cf-3, CD142, Cf3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14066
HGNC: HGNC:3541
Homologene: 1511
Meis3
Name: Meis homeobox 3
Synonyms: Mrg2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17537
Homologene: 7425
Myo1c
Name: myosin IC
Synonyms: C80397, myosin-Ibeta, myr2, mm1beta
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17913
HGNC: HGNC:7597
Homologene: 32046
Fyb2
Name: FYN binding protein 2
Synonyms: 1700024P16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242594
Homologene: 52981
Mpo
Name: myeloperoxidase
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17523
HGNC: HGNC:7218
Homologene: 55450
Or8a1
Name: olfactory receptor family 8 subfamily A member 1
Synonyms: M71, GA_x6K02T2PVTD-31408136-31407207, MOR171-2, Olfr151
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 406176
HGNC: HGNC:8469
Homologene: 12726
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381293
Homologene: 8916
Hipk3
Name: homeodomain interacting protein kinase 3
Synonyms: DYRK6, FIST3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15259
HGNC: HGNC:4915
Homologene: 55923
Grm8
Name: glutamate receptor, metabotropic 8
Synonyms: mGluR8, Gprc1h
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14823
HGNC: HGNC:4600
Homologene: 654
Tor1aip2
Name: torsin A interacting protein 2
Synonyms: LULL1, 1110020D10Rik, Ifrg15, 15kDa
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240832
Homologene: 17028
Nags
Name: N-acetylglutamate synthase
Synonyms: 1700120E20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217214
Homologene: 77363
Apol10a
Name: apolipoprotein L 10A
Synonyms: 9030421J09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 245282
Homologene: 129975
Glb1l
Name: galactosidase, beta 1-like
Synonyms: 4833408P15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74577
Homologene: 75208
Or2y1
Name: olfactory receptor family 2 subfamily Y member 1
Synonyms: MOR256-42P, GA_x6K02T2QP88-5941817-5940888, MOR256-42P, MOR256-41P, Olfr1549-ps1, Olfr1385
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258027
Homologene: 86692
Slc6a17
Name: solute carrier family 6 (neurotransmitter transporter), member 17
Synonyms: D130012J15Rik, NTT4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229706
Homologene: 27775
Klre1
Name: killer cell lectin-like receptor family E member 1
Synonyms: Klre-1, NKG2I
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243655
Homologene: 17794
Mrgprb5
Name: MAS-related GPR, member B5
Synonyms: MrgB5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404239
Homologene: 115575
Ighe
Name: Immunoglobulin heavy constant epsilon
Synonyms: LOC380792, Gm900
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380792
HGNC: HGNC:5522
Nkain4
Name: Na+/K+ transporting ATPase interacting 4
Synonyms: C030019F02Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 58237
Homologene: 10978
Dusp13b
Name: dual specificity phosphatase 13B
Synonyms: TMDP, LMW-DSP6, TS-DSP6, LOC382853, Dusp13
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27389
Homologene: 121602
Slc2a10
Name: solute carrier family 2 (facilitated glucose transporter), member 10
Synonyms: Glut10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 170441
Homologene: 38551
Ovca2
Name: candidate tumor suppressor in ovarian cancer 2
Synonyms: 9030414M07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246257
Homologene: 6086
Or4k1
Name: olfactory receptor family 4 subfamily K member 1
Synonyms: GA_x6K02T2PMLR-5831021-5830086, MOR246-1P, Olfr728
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258039
Homologene: 74224
Lekr1
Name: leucine, glutamate and lysine rich 1
Synonyms: EG546798, Gm6534
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 624866
Homologene: 54497
Ldhc
Name: lactate dehydrogenase C
Synonyms: Ldh-3, Ldh3, Ldhc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16833
HGNC: HGNC:6544
Homologene: 22767
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 75,202,417 bp
  • A to G, chromosome 1 at 136,525,806 bp
  • T to A, chromosome 1 at 156,065,409 bp
  • A to C, chromosome 2 at 85,430,539 bp
  • C to T, chromosome 2 at 104,446,571 bp
  • T to C, chromosome 2 at 165,515,208 bp
  • C to T, chromosome 2 at 180,944,177 bp
  • T to A, chromosome 3 at 54,698,601 bp
  • C to A, chromosome 3 at 65,683,959 bp
  • T to G, chromosome 3 at 107,471,387 bp
  • C to T, chromosome 3 at 121,731,674 bp
  • G to A, chromosome 3 at 158,063,713 bp
  • C to T, chromosome 4 at 14,822,739 bp
  • T to A, chromosome 4 at 104,990,235 bp
  • A to T, chromosome 4 at 129,653,984 bp
  • T to C, chromosome 6 at 27,363,191 bp
  • A to G, chromosome 6 at 129,582,266 bp
  • A to T, chromosome 6 at 142,829,282 bp
  • G to T, chromosome 7 at 16,182,330 bp
  • G to T, chromosome 7 at 39,537,898 bp
  • G to A, chromosome 7 at 46,866,531 bp
  • A to G, chromosome 7 at 48,168,789 bp
  • T to A, chromosome 7 at 64,372,486 bp
  • A to G, chromosome 7 at 66,708,482 bp
  • A to T, chromosome 7 at 83,943,637 bp
  • A to G, chromosome 7 at 127,534,917 bp
  • G to A, chromosome 8 at 104,619,985 bp
  • A to G, chromosome 9 at 37,730,264 bp
  • A to G, chromosome 10 at 128,487,769 bp
  • T to G, chromosome 11 at 49,494,957 bp
  • C to T, chromosome 11 at 75,178,743 bp
  • C to T, chromosome 11 at 75,671,635 bp
  • C to A, chromosome 11 at 77,449,433 bp
  • A to G, chromosome 11 at 87,795,368 bp
  • C to A, chromosome 11 at 102,146,521 bp
  • T to C, chromosome 12 at 113,269,288 bp
  • A to G, chromosome 14 at 21,748,473 bp
  • T to A, chromosome 14 at 50,139,724 bp
  • C to T, chromosome 15 at 77,488,851 bp
  • G to A, chromosome 18 at 77,065,720 bp
  • A to G, chromosome 19 at 44,835,477 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6713 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044831-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.