Strain Name:
C57BL/6J-MtgxR6809Btlr/Mmmh
Stock Number:
044922-MU
Citation ID:
RRID:MMRRC_044922-MU
Other Names:
R6809 (G1)
Major Collection:

Strain Information

Mapk1
Name: mitogen-activated protein kinase 1
Synonyms: Prkm1, MAPK2, Erk2, p42mapk, 9030612K14Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 26413
HGNC: HGNC:6871
Homologene: 37670
Abtb3
Name: ankyrin repeat and BTB domain containing 3
Synonyms: Btbd11, 6330404E16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74007
Homologene: 72536
Wdfy3
Name: WD repeat and FYVE domain containing 3
Synonyms: D5Ertd66e, Bwf1, 2610509D04Rik, Bchs, Ggtb3, Alfy
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72145
Homologene: 22855
Pkn2
Name: protein kinase N2
Synonyms: 6030436C20Rik, Stk7, Prkcl2, PRK2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109333
HGNC: HGNC:9406
Homologene: 2054
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229227
Homologene: 52105
Psip1
Name: PC4 and SFRS1 interacting protein 1
Synonyms: Psip2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 101739
HGNC: HGNC:9527
Homologene: 13242
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Phf11d
Name: PHD finger protein 11D
Synonyms: D14Ertd668e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219132
Homologene: 87807
Sgcb
Name: sarcoglycan, beta (dystrophin-associated glycoprotein)
Synonyms: beta-SG
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 24051
Homologene: 195
Slf2
Name: SMC5-SMC6 complex localization factor 2
Synonyms: Fam178a, 6030443O07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226151
VEGA: 19
Homologene: 23077
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Ten-m4, l7Rn3, Odz4, l(7)-3Rn, ELM2, Doc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Mrpl48
Name: mitochondrial ribosomal protein L48
Synonyms: D4Ertd786e, CGI-118, 1810030E20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52443
Homologene: 32294
Pnpla6
Name: patatin-like phospholipase domain containing 6
Synonyms: Nte, Swiss-cheese, MSws
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 50767
Homologene: 21333
Dapk1
Name: death associated protein kinase 1
Synonyms: 2810425C21Rik, DAP-Kinase, D13Ucla1, 2310039H24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69635
VEGA: 13
HGNC: HGNC:2674
Homologene: 3626
Ubqln4
Name: ubiquilin 4
Synonyms: UBIN
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 94232
HGNC: HGNC:1237
Homologene: 41346
Bloc1s5
Name: biogenesis of lysosomal organelles complex-1, subunit 5, muted
Synonyms: BLOC-1 subunit, 1810074A19Rik, mu, Muted
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17828
VEGA: 13
Homologene: 16374
Apeh
Name: acylpeptide hydrolase
Synonyms: N-acylaminoacyl peptide hydrolase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235606
HGNC: HGNC:586
Homologene: 1240
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: b2b1554Clo, A2mr, CD91
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Crb1
Name: crumbs family member 1, photoreceptor morphogenesis associated
Synonyms: A930008G09Rik, 7530426H14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170788
HGNC: HGNC:2343
Homologene: 8092
Col28a1
Name: collagen, type XXVIII, alpha 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 213945
Homologene: 66345
Dpysl4
Name: dihydropyrimidinase-like 4
Synonyms: Ulip4, CRMP-3, Drp-4, DPY4, Crmp3, unc-33-like phosphoprotein 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26757
HGNC: HGNC:3016
Homologene: 4691
Hrc
Name: histidine rich calcium binding protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15464
HGNC: HGNC:5178
Homologene: 137234
Adgrv1
Name: adhesion G protein-coupled receptor V1
Synonyms: Mgr1, Mass1, Gpr98, VLGR1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 110789
Homologene: 19815
Pak5
Name: p21 (RAC1) activated kinase 5
Synonyms: Pak7, Pak5, 2900083L08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241656
Homologene: 22211
Dlgap2
Name: DLG associated protein 2
Synonyms: PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, Sapap2, DAP2, 6430596N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244310
HGNC: HGNC:2906
Homologene: 3484
Mroh2a
Name: maestro heat-like repeat family member 2A
Synonyms: ENSMUSG00000044873, OTTMUSG00000020804, Heatr7b1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 100040766
Homologene: 85300
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: PAR3beta, Als2cr19, PAR3L, 1810008K04Rik, PAR3B, 2010002N16Rik, 2810455B10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72823
Homologene: 35389
Vmn2r85
Name: vomeronasal 2, receptor 85
Synonyms: EG623734
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 623734
Homologene: 129606
Aox3
Name: aldehyde oxidase 3
Synonyms: 1200011D03Rik, AOH1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71724
Homologene: 90899
Rufy4
Name: RUN and FYVE domain containing 4
Synonyms: F930048N03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 435626
Homologene: 52359
Nol4
Name: nucleolar protein 4
Synonyms: 4930568N03Rik, LOC383304, 1700013J13Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 319211
HGNC: HGNC:7870
Homologene: 36142
Slc27a6
Name: solute carrier family 27 (fatty acid transporter), member 6
Synonyms: FATP6, 4732438L20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225579
Homologene: 38385
Taar7b
Name: trace amine-associated receptor 7B
Synonyms: LOC209517
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209517
Homologene: 134040
Padi2
Name: peptidyl arginine deiminase, type II
Synonyms: Pdi2, Pdi, PAD type II
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18600
Homologene: 7214
Gtdc1
Name: glycosyltransferase-like domain containing 1
Synonyms: E330008O22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227835
Homologene: 32590
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Ncln
Name: nicalin
Synonyms: 3100002P13Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103425
Homologene: 10604
Rgs22
Name: regulator of G-protein signalling 22
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 626596
Homologene: 75047
Pramel14
Name: PRAME like 14
Synonyms: Pramef17, Gm13107
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 626943
Homologene: 129642
Fut9
Name: fucosyltransferase 9
Synonyms: mFUT9, mFuc-TIX
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14348
HGNC: HGNC:4020
Homologene: 4800
Lrrc34
Name: leucine rich repeat containing 34
Synonyms: Spata34, 1700007J06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71827
Homologene: 27419
Krt36
Name: keratin 36
Synonyms: keratin 5, Krt1-5, Krt1-22, HRa-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16673
HGNC: HGNC:6454
Homologene: 88459
Or2y1e
Name: olfactory receptor family 2 subfamily Y member 1E
Synonyms: MOR256-27, Olfr1391, GA_x6K02T2QP88-6107233-6106298
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258460
Homologene: 17264
Paqr5
Name: progestin and adipoQ receptor family member V
Synonyms: 0610010I15Rik, mPRg
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74090
Homologene: 9788
Ugt1a10
Name: UDP glycosyltransferase 1 family, polypeptide A10
Synonyms: A13
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 394430
Homologene: 133281
Hoxd9
Name: homeobox D9
Synonyms: Hox-4.4, Hox-5.2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15438
HGNC: HGNC:5140
Homologene: 8409
Spata4
Name: spermatogenesis associated 4
Synonyms: SRG2, 1700001N01Rik, TSARG2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69281
Homologene: 15868
Ikzf2
Name: IKAROS family zinc finger 2
Synonyms: Helios, Zfpn1a2, A730095J18Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22779
Homologene: 22659
Slc29a2
Name: solute carrier family 29 (nucleoside transporters), member 2
Synonyms: HNP36, ENT2, Der12
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13340
VEGA: 19
Homologene: 37493
Or5g25
Name: olfactory receptor family 5 subfamily G member 25
Synonyms: MOR175-2, Olfr1002, GA_x6K02T2Q125-47127746-47126790
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258566
Homologene: 104131
A130010J15Rik
Name: RIKEN cDNA A130010J15 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319266
Homologene: 17592
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 58,118,681 bp
  • G to A, chromosome 1 at 62,161,181 bp
  • T to C, chromosome 1 at 69,570,502 bp
  • G to A, chromosome 1 at 74,133,047 bp
  • T to A, chromosome 1 at 88,055,925 bp
  • G to T, chromosome 1 at 88,235,216 bp
  • A to G, chromosome 1 at 139,243,126 bp
  • T to A, chromosome 1 at 193,174,781 bp
  • G to C, chromosome 2 at 44,575,551 bp
  • A to G, chromosome 2 at 44,825,384 bp
  • A to G, chromosome 2 at 74,699,246 bp
  • T to C, chromosome 2 at 76,863,639 bp
  • G to A, chromosome 2 at 85,647,973 bp
  • T to G, chromosome 2 at 136,097,581 bp
  • T to A, chromosome 3 at 30,634,600 bp
  • A to G, chromosome 3 at 36,874,282 bp
  • A to T, chromosome 3 at 88,555,372 bp
  • G to A, chromosome 3 at 142,799,004 bp
  • T to A, chromosome 4 at 25,620,647 bp
  • A to G, chromosome 4 at 83,468,642 bp
  • A to G, chromosome 4 at 140,946,766 bp
  • A to G, chromosome 4 at 143,993,081 bp
  • T to G, chromosome 5 at 73,640,693 bp
  • C to A, chromosome 5 at 94,683,418 bp
  • C to T, chromosome 5 at 101,923,947 bp
  • T to C, chromosome 6 at 7,999,468 bp
  • A to G, chromosome 7 at 45,336,379 bp
  • G to A, chromosome 7 at 96,553,496 bp
  • A to G, chromosome 7 at 100,546,367 bp
  • A to G, chromosome 7 at 139,093,660 bp
  • G to A, chromosome 8 at 3,534,611 bp
  • G to T, chromosome 8 at 14,179,619 bp
  • A to C, chromosome 8 at 54,602,333 bp
  • T to A, chromosome 9 at 61,968,782 bp
  • G to A, chromosome 9 at 108,092,679 bp
  • T to C, chromosome 10 at 24,000,858 bp
  • A to G, chromosome 10 at 81,487,678 bp
  • A to G, chromosome 10 at 85,631,376 bp
  • A to G, chromosome 10 at 127,555,056 bp
  • T to A, chromosome 10 at 130,425,926 bp
  • C to T, chromosome 11 at 29,803,161 bp
  • G to T, chromosome 11 at 49,327,860 bp
  • A to T, chromosome 11 at 100,105,509 bp
  • G to A, chromosome 13 at 11,726,930 bp
  • A to G, chromosome 13 at 38,603,985 bp
  • A to G, chromosome 13 at 60,751,289 bp
  • A to T, chromosome 13 at 81,472,953 bp
  • C to A, chromosome 14 at 59,356,395 bp
  • C to G, chromosome 15 at 36,048,764 bp
  • A to T, chromosome 16 at 17,035,462 bp
  • T to A, chromosome 18 at 22,920,825 bp
  • A to G, chromosome 18 at 58,605,054 bp
  • T to C, chromosome 19 at 5,029,243 bp
  • C to A, chromosome 19 at 44,943,468 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6809 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044922-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.