Strain Name:
C57BL/6J-MtgxR6927Btlr/Mmmh
Stock Number:
045044-MU
Citation ID:
RRID:MMRRC_045044-MU
Other Names:
R6927 (G1)
Major Collection:

Strain Information

Adck2
Name: aarF domain containing kinase 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 57869
Homologene: 49103
Kdm4b
Name: lysine (K)-specific demethylase 4B
Synonyms: 4732474L06Rik, Jmjd2b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 193796
Homologene: 27773
Map4k4
Name: mitogen-activated protein kinase kinase kinase kinase 4
Synonyms: Nik, 9430080K19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26921
HGNC: HGNC:6866
Homologene: 7442
Zfhx3
Name: zinc finger homeobox 3
Synonyms: WBP9, A230102L03Rik, Atbf1, Sci
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11906
HGNC: HGNC:777
Homologene: 21366
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Fasn
Name: fatty acid synthase
Synonyms: FAS, A630082H08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14104
HGNC: HGNC:3594
Homologene: 55800
Atp9b
Name: ATPase, class II, type 9B
Synonyms: IIb
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 50771
VEGA: 18
Homologene: 21915
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
L3mbtl3
Name: L3MBTL3 histone methyl-lysine binding protein
Synonyms: MBT-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237339
Homologene: 18226
Puf60
Name: poly-U binding splicing factor 60
Synonyms: 2810454F19Rik, 2410104I19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67959
VEGA: 15
Homologene: 8614
Ahi1
Name: Abelson helper integration site 1
Synonyms: Ahi-1, 1700015F03Rik, D10Bwg0629e, Jouberin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52906
VEGA: 10
Homologene: 9762
Hey2
Name: hairy/enhancer-of-split related with YRPW motif 2
Synonyms: CHF1, Hrt2, Herp1, Hesr2, bHLHb32
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15214
HGNC: HGNC:4881
Homologene: 22705
Robo2
Name: roundabout guidance receptor 2
Synonyms: 9430089E08Rik, D230004I22Rik, 2600013A04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268902
Homologene: 43188
Krt25
Name: keratin 25
Synonyms: 4631426H08Rik, mIRSa1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70810
Homologene: 77127
Ass1
Name: argininosuccinate synthetase 1
Synonyms: ASS, Ass-1, fold
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Zfp335
Name: zinc finger protein 335
Synonyms: 1810045J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329559
Homologene: 11129
Macrod2
Name: mono-ADP ribosylhydrolase 2
Synonyms: 2610107G07Rik, 1110033L15Rik, 2900006F19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72899
Homologene: 85987
Flvcr1
Name: feline leukemia virus subgroup C cellular receptor 1
Synonyms: 9630055N22Rik, Mfsd7b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226844
Homologene: 56661
Fan1
Name: FANCD2/FANCI-associated nuclease 1
Synonyms: 6030441H18Rik, Mtmr15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330554
Homologene: 45598
Vwc2
Name: von Willebrand factor C domain containing 2
Synonyms: A930041G11Rik, Brorin, cradin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319922
Homologene: 18542
Gask1b
Name: golgi associated kinase 1B
Synonyms: 2210419I08Rik, Ened, 1110032E23Rik, Fam198b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 68659
Homologene: 9590
Nucb1
Name: nucleobindin 1
Synonyms: MTEST82, B230337F23Rik, Calnuc
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18220
HGNC: HGNC:8043
Homologene: 4507
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Tmc2
Name: transmembrane channel-like gene family 2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192140
Homologene: 25877
Dnhd1
Name: dynein heavy chain domain 1
Synonyms: 8030491N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77505
Homologene: 131117
Piezo2
Name: piezo-type mechanosensitive ion channel component 2
Synonyms: 9430028L06Rik, 9030411M15Rik, Fam38b2, Piezo2, Fam38b
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 667742
Homologene: 49695
Fhl5
Name: four and a half LIM domains 5
Synonyms: 1700027G07Rik, ACT
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 57756
Homologene: 23230
Plekhb2
Name: pleckstrin homology domain containing, family B (evectins) member 2
Synonyms: Phdc, evt-2, 2310009M15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226971
Homologene: 9938
Lipm
Name: lipase, family member M
Synonyms: 4632427C23Rik, Lipl3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78753
VEGA: 19
Homologene: 28267
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56552
Homologene: 135915
Chrnd
Name: cholinergic receptor, nicotinic, delta polypeptide
Synonyms: Achr-4, Acrd
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11447
HGNC: HGNC:1965
Homologene: 37340
Pcnx1
Name: pecanex 1
Synonyms: 3526401J03Rik, 2900024E21Rik, Pcnx
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 54604
VEGA: 12
Homologene: 40997
Vstm4
Name: V-set and transmembrane domain containing 4
Synonyms: E130203B14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 320736
Homologene: 18707
Itga10
Name: integrin, alpha 10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213119
HGNC: HGNC:6135
Homologene: 2697
Impa1
Name: inositol (myo)-1(or 4)-monophosphatase 1
Synonyms: lithium-sensitive myo-inositol monophosphatase A1, 2610002K09Rik, 2900059K10Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55980
HGNC: HGNC:6050
Homologene: 4043
Fam118a
Name: family with sequence similarity 118, member A
Synonyms: C230014M12Rik, 3110048E14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73225
VEGA: 15
HGNC: HGNC:1313
Homologene: 9911
Prl2c5
Name: prolactin family 2, subfamily c, member 5
Synonyms: MRP-4, PLF-4, Mrpplf4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107849
Homologene: 40763
Bag6
Name: BCL2-associated athanogene 6
Synonyms: D17H6S52E, G3, 2410045D21Rik, Scythe, Bat3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224727
Homologene: 3409
Slc22a23
Name: solute carrier family 22, member 23
Synonyms: 3110004L20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73102
Homologene: 41457
Ppp2r3a
Name: protein phosphatase 2, regulatory subunit B'', alpha
Synonyms: 3222402P14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235542
HGNC: HGNC:9307
Homologene: 20595
Fdps
Name: farnesyl diphosphate synthetase
Synonyms: Fdpsl1, 6030492I17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 110196
HGNC: HGNC:3631
Homologene: 1519
Cyp3a13
Name: cytochrome P450, family 3, subfamily a, polypeptide 13
Synonyms: IIIAm2, steroid inducible
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13113
Homologene: 133564
Abcc10
Name: ATP-binding cassette, sub-family C member 10
Synonyms: Mrp7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224814
HGNC: HGNC:52
Homologene: 58616
Hoxc5
Name: homeobox C5
Synonyms: Hox-3.4, Hox-6.2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 15424
HGNC: HGNC:5127
Homologene: 41296
Tas2r115
Name: taste receptor, type 2, member 115
Synonyms: Tas2r15, mGR15, mt2r49, T2R15
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 353325
Zfp488
Name: zinc finger protein 488
Synonyms: LOC382867
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 382867
Homologene: 17688
Mgat4d
Name: MGAT4 family, member C
Synonyms: 4933434I20Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67555
Homologene: 128538
Cd300ld2
Name: CD300 molecule like family member D2
Synonyms: Gm11709
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 629970
Mad2l2
Name: MAD2 mitotic arrest deficient-like 2
Synonyms: MAD2B, REV7, 2310033C13Rik, G1-453-4, repro22
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 71890
HGNC: HGNC:6764
Homologene: 4624
Or2t46
Name: olfactory receptor family 2 subfamily T member 46
Synonyms: GA_x6K02T2NKPP-844642-843680, MOR275-5, MOR275-11_p, Olfr325
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258261
Homologene: 133015
Slc36a3
Name: solute carrier family 36 (proton/amino acid symporter), member 3
Synonyms: tramdorin2, PAT3, TRAMD2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 215332
Homologene: 76175
Slc25a42
Name: solute carrier family 25, member 42
Synonyms: 2900084M01Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 73095
Homologene: 74852
Iqcj
Name: IQ motif containing J
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 208426
Homologene: 132095
Pdf
Name: peptide deformylase (mitochondrial)
Synonyms: 2610019N19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68023
Homologene: 69354
Pcdhga2
Name: protocadherin gamma subfamily A, 2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93710
HGNC: HGNC:8700
Homologene: 69262
Gpr31b
Name: G protein-coupled receptor 31, D17Leh66b region
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 436440
VEGA: 17
HGNC: HGNC:4486
Homologene: 48337
Rdh16f1
Name: RDH16 family member 1
Synonyms: Gm28046
Type: Gene
Species: Mouse
Chromosome: 10
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 34,876,901 bp
  • T to A, chromosome 1 at 40,011,682 bp
  • T to C, chromosome 1 at 87,198,712 bp
  • T to C, chromosome 1 at 191,025,664 bp
  • T to C, chromosome 2 at 31,514,801 bp
  • A to G, chromosome 2 at 130,261,380 bp
  • A to T, chromosome 2 at 142,256,521 bp
  • A to G, chromosome 2 at 164,893,720 bp
  • A to G, chromosome 3 at 10,315,288 bp
  • T to C, chromosome 3 at 68,047,291 bp
  • T to C, chromosome 3 at 79,941,462 bp
  • T to C, chromosome 3 at 89,093,651 bp
  • T to C, chromosome 3 at 96,656,714 bp
  • T to C, chromosome 4 at 25,213,681 bp
  • T to A, chromosome 4 at 148,140,954 bp
  • G to A, chromosome 5 at 137,895,284 bp
  • T to C, chromosome 6 at 39,584,064 bp
  • A to G, chromosome 6 at 124,039,098 bp
  • T to A, chromosome 6 at 132,737,932 bp
  • C to T, chromosome 7 at 45,498,858 bp
  • T to A, chromosome 7 at 64,372,486 bp
  • C to A, chromosome 7 at 105,715,563 bp
  • G to A, chromosome 8 at 45,024,495 bp
  • A to G, chromosome 8 at 70,188,923 bp
  • A to G, chromosome 8 at 83,354,867 bp
  • A to T, chromosome 8 at 107,048,201 bp
  • C to G, chromosome 8 at 108,956,821 bp
  • G to C, chromosome 9 at 101,175,348 bp
  • A to T, chromosome 10 at 21,055,069 bp
  • T to A, chromosome 10 at 26,292,669 bp
  • A to T, chromosome 10 at 30,834,417 bp
  • T to C, chromosome 10 at 127,788,692 bp
  • C to A, chromosome 11 at 11,154,250 bp
  • T to A, chromosome 11 at 55,129,693 bp
  • A to G, chromosome 11 at 58,581,665 bp
  • G to A, chromosome 11 at 72,913,157 bp
  • A to T, chromosome 11 at 99,317,379 bp
  • A to T, chromosome 11 at 107,054,595 bp
  • T to A, chromosome 11 at 115,013,793 bp
  • T to A, chromosome 11 at 120,808,289 bp
  • T to C, chromosome 12 at 81,917,812 bp
  • A to T, chromosome 12 at 115,120,174 bp
  • A to T, chromosome 13 at 13,182,918 bp
  • G to T, chromosome 13 at 34,344,379 bp
  • T to A, chromosome 14 at 32,864,002 bp
  • A to G, chromosome 14 at 33,970,798 bp
  • T to A, chromosome 15 at 76,075,814 bp
  • T to C, chromosome 15 at 85,044,837 bp
  • T to A, chromosome 15 at 103,015,375 bp
  • T to A, chromosome 16 at 73,982,058 bp
  • A to G, chromosome 17 at 13,051,878 bp
  • G to A, chromosome 17 at 35,145,922 bp
  • A to T, chromosome 17 at 46,324,391 bp
  • T to C, chromosome 17 at 56,399,435 bp
  • A to C, chromosome 18 at 37,670,666 bp
  • A to G, chromosome 18 at 63,032,986 bp
  • T to C, chromosome 18 at 80,891,857 bp
  • T to C, chromosome 19 at 34,101,163 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6927 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045044-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.