Strain Name:
C57BL/6J-MtgxR7692Btlr/Mmmh
Stock Number:
045756-MU
Citation ID:
RRID:MMRRC_045756-MU
Other Names:
R7692 (G1)
Major Collection:

Strain Information

Zfand6
Name: zinc finger, AN1-type domain 6
Synonyms: 3110005P07Rik, Za20d3, Awp1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 65098
Homologene: 10372
Slc2a1
Name: solute carrier family 2 (facilitated glucose transporter), member 1
Synonyms: Glut-1, M100200, Glut1, Rgsc200
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20525
Homologene: 68520
Sbno1
Name: strawberry notch 1
Synonyms: sno, 9330180L10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243272
Homologene: 10055
Eif3e
Name: eukaryotic translation initiation factor 3, subunit E
Synonyms: 48kDa, eIF3-p48, Eif3s6, Int6, eIF3-p46
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16341
VEGA: 15
HGNC: HGNC:3277
Homologene: 1205
Arid2
Name: AT-rich interaction domain 2
Synonyms: zipzap/p200, 1700124K17Rik, 4432409D24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77044
Homologene: 14601
Gfod1
Name: glucose-fructose oxidoreductase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 328232
VEGA: 13
Homologene: 49581
Uhrf1
Name: ubiquitin-like, containing PHD and RING finger domains, 1
Synonyms: ICBP90, Np95
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18140
Homologene: 7866
Tenm4
Name: teneurin transmembrane protein 4
Synonyms: Ten-m4, l7Rn3, Odz4, l(7)-3Rn, ELM2, Doc4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23966
Homologene: 8034
Enpp3
Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Synonyms: CD203c
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209558
VEGA: 10
HGNC: HGNC:3358
Homologene: 3683
Angptl1
Name: angiopoietin-like 1
Synonyms: ANGPT3, ANG3, ANG-3, ANG3, ARP1, 2810039D03Rik, ANGY
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 72713
HGNC: HGNC:489
Homologene: 128467
Timm23
Name: translocase of inner mitochondrial membrane 23
Synonyms: Tim23
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 53600
Homologene: 9651
Golm1
Name: golgi membrane protein 1
Synonyms: Golph2, GP73, PSEC0257, D030064E01Rik, 2310001L02Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105348
VEGA: 13
Homologene: 12346
Phlpp1
Name: PH domain and leucine rich repeat protein phosphatase 1
Synonyms: Plekhe1, Phlpp
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98432
Homologene: 11015
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Vmn1r206
Name: vomeronasal 1 receptor 206
Synonyms: V1rh7
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171250
Homologene: 110880
Dnah1
Name: dynein, axonemal, heavy chain 1
Synonyms: E030034C22Rik, Dnahc1, G1-415-19, MDHC7, ferf1, B230373P09Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110084
VEGA: 14
HGNC: HGNC:2940
Homologene: 67131
Tab2
Name: TGF-beta activated kinase 1/MAP3K7 binding protein 2
Synonyms: A530078N03Rik, 1110030N06Rik, Map3k7ip2, Tak1 binding protein 2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68652
Homologene: 9019
Nlrp4a
Name: NLR family, pyrin domain containing 4A
Synonyms: Nalp-eta, E330028A19Rik, Nalp4a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243880
Homologene: 79696
Mrpl30
Name: mitochondrial ribosomal protein L30
Synonyms: MRP-L28, 2310001L22Rik, Rpml28
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 107734
Homologene: 32675
Gen1
Name: GEN1, Holliday junction 5' flap endonuclease
Synonyms: 5830483C08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 209334
VEGA: 12
Homologene: 35313
Ado
Name: 2-aminoethanethiol dioxygenase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 211488
VEGA: 10
Homologene: 13121
Hc
Name: hemolytic complement
Synonyms: C5, He, Hfib2, C5a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 15139
HGNC: HGNC:1331
Homologene: 20412
Muc5b
Name: mucin 5, subtype B, tracheobronchial
Synonyms: MUC5, 2300002I04Rik, MUC9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74180
HGNC: HGNC:7516
Homologene: 136756
Tmem229a
Name: transmembrane protein 229A
Synonyms: 6332401O19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319832
Homologene: 85312
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215772
Homologene: 100289
Slc4a10
Name: solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
Synonyms: NCBE
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94229
Homologene: 23340
Or5b98
Name: olfactory receptor family 5 subfamily B member 98
Synonyms: Olfr1450, GA_x6K02T2RE5P-3283121-3284098, MOR202-33
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258368
Speg
Name: SPEG complex locus
Synonyms: D1Bwg1450e, BPEG, Apeg1, SPEG, SPEGalpha, SPEGbeta
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 11790
Homologene: 55619
Eml6
Name: echinoderm microtubule associated protein like 6
Synonyms: 2900083P10Rik, C230094A16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237711
Homologene: 104282
Ugt2a1
Name: UDP glucuronosyltransferase 2 family, polypeptide A1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 94215
Homologene: 136808
Smarcal1
Name: SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Synonyms: 6030401P21Rik, Mharp
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 54380
Homologene: 8558
Adam26b
Name: a disintegrin and metallopeptidase domain 26B
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382007
Homologene: 128363
Sardh
Name: sarcosine dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 192166
Homologene: 5149
Prl5a1
Name: prolactin family 5, subfamily a, member 1
Synonyms: PLP-L, 1600013P04Rik, Prlpl, D13Wsu14e
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 28078
Homologene: 11378
Fmo1
Name: flavin containing monooxygenase 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14261
HGNC: HGNC:3769
Homologene: 55520
Evi5l
Name: ecotropic viral integration site 5 like
Synonyms: 1700084G18Rik, 3110007G05Rik, B130050I23Rik, 2310039H16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 213027
Homologene: 134635
Or10g1
Name: olfactory receptor family 10 subfamily G member 1
Synonyms: GA_x6K02T2RJGY-583652-584608, MOR223-6, Olfr1510
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258423
HGNC: HGNC:8170
Homologene: 87788
Gabrb3
Name: GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
Synonyms: A230092K12Rik, beta3, Gabrb-3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14402
HGNC: HGNC:4083
Homologene: 633
Steap4
Name: STEAP family member 4
Synonyms: Tnfaip9, Tiarp
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117167
Homologene: 36422
Lztfl1
Name: leucine zipper transcription factor-like 1
Synonyms: 5530402H04Rik, 6130400H19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 93730
HGNC: HGNC:6741
Homologene: 41368
Vmn2r106
Name: vomeronasal 2, receptor 106
Synonyms: EG224576
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224576
Homologene: 135824
Clvs1
Name: clavesin 1
Synonyms: Rlbp1l1, 4933402J24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74438
Homologene: 65267
Hspa14
Name: heat shock protein 14
Synonyms: NST-1, HSP70L1, 70kDa, Hsp70-4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 50497
Homologene: 74307
Mgat2
Name: mannoside acetylglucosaminyltransferase 2
Synonyms: GNT2, CDGS2, GNT-II
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217664
HGNC: HGNC:7045
Homologene: 1806
Pla2g4d
Name: phospholipase A2, group IVD
Synonyms: Pla2delta, 2610311B01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78390
Homologene: 52252
Ugdh
Name: UDP-glucose dehydrogenase
Synonyms: Udpgdh
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22235
Homologene: 2520
Fcgr3
Name: Fc receptor, IgG, low affinity III
Synonyms: CD16, Fcg receptor III, FcgammaRIII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14131
HGNC: HGNC:3616
Homologene: 47936
Lzts3
Name: leucine zipper, putative tumor suppressor family member 3
Synonyms: Prosapip1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241638
Homologene: 8824
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 37,895,358 bp
  • T to G, chromosome 1 at 72,586,020 bp
  • A to G, chromosome 1 at 75,401,190 bp
  • T to C, chromosome 1 at 106,281,402 bp
  • A to G, chromosome 1 at 156,845,315 bp
  • T to A, chromosome 1 at 162,833,833 bp
  • A to C, chromosome 1 at 171,054,092 bp
  • T to C, chromosome 2 at 3,496,606 bp
  • A to G, chromosome 2 at 27,197,639 bp
  • C to A, chromosome 2 at 35,024,149 bp
  • T to C, chromosome 2 at 62,303,964 bp
  • T to C, chromosome 2 at 120,279,295 bp
  • T to C, chromosome 2 at 130,635,386 bp
  • T to C, chromosome 4 at 9,350,739 bp
  • T to C, chromosome 4 at 119,136,265 bp
  • T to C, chromosome 5 at 7,976,976 bp
  • T to C, chromosome 5 at 65,417,615 bp
  • A to G, chromosome 5 at 87,486,727 bp
  • T to C, chromosome 5 at 121,321,564 bp
  • T to G, chromosome 5 at 124,405,646 bp
  • C to A, chromosome 6 at 24,955,212 bp
  • G to A, chromosome 7 at 26,449,265 bp
  • A to G, chromosome 7 at 57,816,455 bp
  • G to A, chromosome 7 at 84,633,933 bp
  • A to G, chromosome 7 at 96,895,403 bp
  • A to T, chromosome 7 at 141,853,229 bp
  • C to T, chromosome 8 at 4,200,886 bp
  • G to A, chromosome 8 at 43,520,795 bp
  • C to T, chromosome 9 at 123,712,471 bp
  • A to T, chromosome 10 at 7,911,105 bp
  • A to G, chromosome 10 at 10,411,712 bp
  • G to T, chromosome 10 at 24,784,841 bp
  • G to T, chromosome 10 at 67,548,435 bp
  • A to G, chromosome 11 at 29,753,085 bp
  • T to A, chromosome 12 at 11,242,166 bp
  • A to G, chromosome 12 at 69,184,670 bp
  • T to A, chromosome 13 at 22,620,657 bp
  • C to G, chromosome 13 at 28,150,014 bp
  • T to C, chromosome 13 at 43,201,052 bp
  • A to G, chromosome 13 at 59,640,257 bp
  • T to C, chromosome 14 at 31,292,338 bp
  • A to G, chromosome 14 at 32,180,563 bp
  • T to C, chromosome 14 at 52,410,488 bp
  • C to A, chromosome 15 at 43,263,246 bp
  • T to A, chromosome 15 at 96,356,697 bp
  • T to C, chromosome 17 at 20,285,228 bp
  • A to G, chromosome 17 at 56,312,905 bp
  • A to G, chromosome 19 at 12,953,642 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7692 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045756-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.