Strain Name:
C57BL/6J-MtgxR9049Btlr/Mmmh
Stock Number:
068875-MU
Citation ID:
RRID:MMRRC_068875-MU
Other Names:
R9049 (G1)
Major Collection:

Strain Information

Polr3e
Name: polymerase (RNA) III (DNA directed) polypeptide E
Synonyms: RPC5, Sin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26939
Homologene: 14052
Prkacb
Name: protein kinase, cAMP dependent, catalytic, beta
Synonyms: Pkacb, cAMP-dependent protein kinase C beta
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18749
HGNC: HGNC:9381
Homologene: 121718
Htr3a
Name: 5-hydroxytryptamine (serotonin) receptor 3A
Synonyms: 5-HT3 receptor
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 15561
VEGA: 9
HGNC: HGNC:5297
Homologene: 671
Vcan
Name: versican
Synonyms: DPEAAE, 5430420N07Rik, Cspg2, hdf, heart defect, PG-M
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 13003
HGNC: HGNC:2464
Homologene: 3228
Bpifb3
Name: BPI fold containing family B, member 3
Synonyms: Rya3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 378700
Homologene: 18807
Pipox
Name: pipecolic acid oxidase
Synonyms: Pso
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19193
Homologene: 40640
Aopep
Name: aminopeptidase O
Synonyms: ApO, 2010111I01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72061
HGNC: HGNC:1361
Homologene: 66273
Prex2
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Synonyms: 6230420N16Rik, Depdc2, C030045D06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 109294
Homologene: 23523
Tnks
Name: tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
Synonyms: D130072O21Rik, 4930554K12Rik, mTNKS1, TANK1, tankyrase 1, Parp5a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21951
Homologene: 18405
Nomo1
Name: nodal modulator 1
Synonyms: PM5, D7Ertd156e, Nomo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 211548
Homologene: 13810
Tpp2
Name: tripeptidyl peptidase II
Synonyms: TppII
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22019
Homologene: 2471
Pip5k1c
Name: phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma
Synonyms: PIP5KIgamma
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18717
HGNC: HGNC:8996
Homologene: 69032
Slc12a2
Name: solute carrier family 12, member 2
Synonyms: sodium/potassium/chloride cotransporters, sy-ns, Nkcc1, mBSC2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20496
VEGA: 18
Homologene: 20283
Akap9
Name: A kinase anchor protein 9
Synonyms: G1-448-15, 5730481H23Rik, mei2-5, AKAP450, repro12
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100986
HGNC: HGNC:379
Homologene: 134583
Camkmt
Name: calmodulin-lysine N-methyltransferase
Synonyms: 1700106N22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73582
VEGA: 17
Homologene: 11704
Tmem161b
Name: transmembrane protein 161B
Synonyms: 2810446P07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72745
Homologene: 14519
Lonp2
Name: lon peptidase 2, peroxisomal
Synonyms: 1300002A08Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66887
Homologene: 12050
Ash1l
Name: ASH1 like histone lysine methyltransferase
Synonyms: chromatin remodeling factor, E430018P19Rik, KMT2H, 8030453L17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 192195
Homologene: 10225
Utp15
Name: UTP15 small subunit processome component
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105372
VEGA: 13
Homologene: 6629
Sqle
Name: squalene epoxidase
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20775
Homologene: 2355
Pld3
Name: phospholipase D family member 3
Synonyms: Sam-9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18807
Homologene: 7893
Tnc
Name: tenascin C
Synonyms: hexabrachion, C130033P17Rik, cytotactin, TN-C, tenascin-C, Hxb, TN
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21923
HGNC: HGNC:5318
Homologene: 55636
Tln1
Name: talin 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21894
Homologene: 21267
Pnisr
Name: PNN interacting serine/arginine-rich
Synonyms: Sfrs18, 5730406M06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66625
Homologene: 32802
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Cpne5
Name: copine V
Synonyms: A830083G22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240058
HGNC: HGNC:2318
Homologene: 23266
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Hdhc3, HL19, LOC380889, Dnahc7l, DLP12, Dnahc12, 4921531P07Rik, DHC3, HL-19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Dgkg
Name: diacylglycerol kinase, gamma
Synonyms: 2900055E17Rik, E430001K23Rik, Dagk3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 110197
HGNC: HGNC:2853
Homologene: 1029
Ust
Name: uronyl-2-sulfotransferase
Synonyms: D930010O20Rik, UA2OST
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 338362
VEGA: 10
Homologene: 4174
Cfap58
Name: cilia and flagella associated protein 58
Synonyms: Ccdc147, LOC381229
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381229
VEGA: 19
Homologene: 77312
Or1p1c
Name: olfactory receptor family 1 subfamily P member 1C
Synonyms: MOR133-1, GA_x6K02T2P1NL-4415162-4416133, Olfr406, Olfr406-ps
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258181
HGNC: HGNC:8222
Col6a3
Name: collagen, type VI, alpha 3
Synonyms: Col6a-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12835
HGNC: HGNC:2213
Homologene: 37917
Bpifb5
Name: BPI fold containing family B, member 5
Synonyms: BC018465
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228802
Homologene: 64814
Stard9
Name: StAR related lipid transfer domain containing 9
Synonyms: E230025N21Rik, Kif16a, 4831403C07Rik, N-3 kinesin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668880
Homologene: 130712
Ccdc88b
Name: coiled-coil domain containing 88B
Synonyms: 2610041P08Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 78317
VEGA: 19
Homologene: 49992
3110009E18Rik
Name: RIKEN cDNA 3110009E18 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73103
Homologene: 41754
Or7e169
Name: olfactory receptor family 7 subfamily E member 169
Synonyms: MOR146-2, GA_x6K02T2PVTD-13586614-13585661, Olfr860
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258521
Homologene: 134093
Psma1
Name: proteasome subunit alpha 1
Synonyms: HC2, C2, Pros-30
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26440
HGNC: HGNC:9530
Homologene: 2080
Ptgfr
Name: prostaglandin F receptor
Synonyms: PGF, FP
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19220
HGNC: HGNC:9600
Homologene: 741
Abcc9
Name: ATP-binding cassette, sub-family C member 9
Synonyms: Sur2, SUR2A, SUR2B
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Adgre4
Name: adhesion G protein-coupled receptor E4
Synonyms: Gpr127, FIRE, Emr4, EGF-TM7, D17Ertd479e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52614
VEGA: 17
Homologene: 64640
Mdm1
Name: MDM1 nuclear protein
Synonyms: Mdm-1, transformed mouse 3T3 cell double minute 1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17245
VEGA: 10
Homologene: 9692
Or5m5
Name: olfactory receptor family 5 subfamily M member 5
Synonyms: GA_x6K02T2Q125-47462755-47463693, MOR196-2, Olfr1030
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258581
Homologene: 64892
Tbc1d16
Name: TBC1 domain family, member 16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207592
Homologene: 10380
Vmn2r55
Name: vomeronasal 2, receptor 55
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042499
Homologene: 104040
Cyp4f39
Name: cytochrome P450, family 4, subfamily f, polypeptide 39
Synonyms: 4732474A20Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320997
VEGA: 17
Homologene: 69814
C9orf72
Name: C9orf72, member of C9orf72-SMCR8 complex
Synonyms: 3110043O21Rik, Dennd9
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73205
Homologene: 10137
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Pira13
Name: paired-Ig-like receptor A13
Synonyms: ENSMUSG00000074419, Gm15448
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100041146
Homologene: 134028
Repin1
Name: replication initiator 1
Synonyms: Zfp464, E430037F08Rik, AP4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58887
Homologene: 22810
Clca1
Name: chloride channel accessory 1
Synonyms: gob5, Clca3, gob-5
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 23844
HGNC: HGNC:2015
Homologene: 984
Or5h25
Name: olfactory receptor family 5 subfamily H member 25
Synonyms: MOR113-7P, Olfr193, GA_x54KRFPKG5P-55338697-55337768, Olfr1540-ps1, MOR183-7P, MOR113-7P
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 257972
Homologene: 128162
Akr1b10
Name: aldo-keto reductase family 1, member B10
Synonyms: 2310005E10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67861
Homologene: 128412
Dcun1d1
Name: defective in cullin neddylation 1 domain containing 1
Synonyms: Rp42, Tes3, DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae), pTes3, SCCRO
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 114893
Homologene: 10773
Or1af1
Name: olfactory receptor family 1 subfamily AF member 1
Synonyms: Olfr366, MOR138-5P, MOR138-6, GA_x6K02T2NLDC-33902472-33903401
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 236509
Homologene: 114744
Mdfi
Name: MyoD family inhibitor
Synonyms: I-mfa, I-mf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17240
HGNC: HGNC:6967
Homologene: 21150
Or10g9
Name: olfactory receptor family 10 subfamily G member 9
Synonyms: MOR223-1, GA_x6K02T2PVTD-33699706-33698771, Olfr979
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 259112
VEGA: 9
Homologene: 81556
Prl3a1
Name: prolactin family 3, subfamily a, member 1
Synonyms: 1600016E11Rik, Prlpi, Plpi, PLP-I, PLP-H
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67000
Homologene: 49844
Prop1
Name: paired like homeodomain factor 1
Synonyms: prophet of Pit-1, prophet of Pit1, Prop-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19127
HGNC: HGNC:9455
Homologene: 4558
Or14j6
Name: olfactory receptor family 14 subfamily J member 6
Synonyms: Olfr127, MOR218-7, GA_x6K02T2PSCP-2354126-2355093
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258374
Homologene: 134080
Rcvrn
Name: recoverin
Synonyms: cancer associated retinopathy protein, S-modulin, guanylate cyclase activator
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19674
HGNC: HGNC:9937
Homologene: 2177
Ppif
Name: peptidylprolyl isomerase F (cyclophilin F)
Synonyms: mitochondrial Cyclophilin D, CyP-D, CyP-F, CypD
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105675
HGNC: HGNC:9259
Homologene: 38696
Gm21834
Name: predicted gene, 21834
Type: Gene
Species: Mouse
Chromosome: 17
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to G, chromosome 1 at 11,185,906 bp
  • T to C, chromosome 1 at 43,953,342 bp
  • T to A, chromosome 1 at 90,779,344 bp
  • A to G, chromosome 1 at 120,188,170 bp
  • C to G, chromosome 2 at 37,219,947 bp
  • A to G, chromosome 2 at 85,983,891 bp
  • A to T, chromosome 2 at 120,679,937 bp
  • C to A, chromosome 2 at 153,925,890 bp
  • A to G, chromosome 2 at 154,228,176 bp
  • T to C, chromosome 3 at 35,897,849 bp
  • T to C, chromosome 3 at 89,007,364 bp
  • T to A, chromosome 3 at 145,027,382 bp
  • A to T, chromosome 3 at 146,755,763 bp
  • T to A, chromosome 3 at 151,835,767 bp
  • T to A, chromosome 4 at 21,854,391 bp
  • A to G, chromosome 4 at 35,192,964 bp
  • C to A, chromosome 4 at 43,549,786 bp
  • G to T, chromosome 4 at 64,000,010 bp
  • T to C, chromosome 4 at 144,273,916 bp
  • T to C, chromosome 5 at 4,064,597 bp
  • T to A, chromosome 5 at 121,313,892 bp
  • A to G, chromosome 6 at 34,396,626 bp
  • A to G, chromosome 6 at 48,597,712 bp
  • A to C, chromosome 6 at 73,142,292 bp
  • A to G, chromosome 6 at 142,682,932 bp
  • T to A, chromosome 7 at 3,816,891 bp
  • T to C, chromosome 7 at 12,684,981 bp
  • C to T, chromosome 7 at 27,535,868 bp
  • A to G, chromosome 7 at 46,066,173 bp
  • T to C, chromosome 7 at 114,266,529 bp
  • A to G, chromosome 7 at 120,939,239 bp
  • A to C, chromosome 7 at 141,808,975 bp
  • T to C, chromosome 8 at 34,841,778 bp
  • T to C, chromosome 8 at 86,709,107 bp
  • T to C, chromosome 9 at 19,845,749 bp
  • G to T, chromosome 9 at 40,000,623 bp
  • C to A, chromosome 9 at 48,899,787 bp
  • G to A, chromosome 10 at 8,307,454 bp
  • C to A, chromosome 10 at 81,316,876 bp
  • C to T, chromosome 10 at 118,146,700 bp
  • G to C, chromosome 11 at 50,952,121 bp
  • A to T, chromosome 11 at 67,695,742 bp
  • A to G, chromosome 11 at 74,270,289 bp
  • A to G, chromosome 11 at 77,881,554 bp
  • G to A, chromosome 11 at 119,209,264 bp
  • T to A, chromosome 13 at 27,276,184 bp
  • A to G, chromosome 13 at 63,061,038 bp
  • G to T, chromosome 13 at 84,294,635 bp
  • A to T, chromosome 13 at 89,678,105 bp
  • T to C, chromosome 13 at 98,259,270 bp
  • G to T, chromosome 14 at 25,694,412 bp
  • T to A, chromosome 14 at 26,722,120 bp
  • C to A, chromosome 14 at 68,525,225 bp
  • T to C, chromosome 15 at 59,317,862 bp
  • A to G, chromosome 16 at 22,600,588 bp
  • T to G, chromosome 16 at 59,110,400 bp
  • A to G, chromosome 17 at 29,160,358 bp
  • T to A, chromosome 17 at 32,486,991 bp
  • G to A, chromosome 17 at 37,903,873 bp
  • C to A, chromosome 17 at 47,824,554 bp
  • T to C, chromosome 17 at 55,785,094 bp
  • G to A, chromosome 17 at 57,741,831 bp
  • A to G, chromosome 17 at 85,402,484 bp
  • A to T, chromosome 18 at 57,921,791 bp
  • C to T, chromosome 19 at 6,849,074 bp
  • A to T, chromosome 19 at 48,026,718 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9049 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068875-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.