Strain Name:
C57BL/6J-MtgxR9128Btlr/Mmmh
Stock Number:
068927-MU
Citation ID:
RRID:MMRRC_068927-MU
Other Names:
R9128 (G1)
Major Collection:

Strain Information

Ednrb
Name: endothelin receptor type B
Synonyms: ETb, ETR-b, Sox10m1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13618
VEGA: 14
HGNC: HGNC:3180
Homologene: 89
Snta1
Name: syntrophin, acidic 1
Synonyms: Snt1, alpha1-syntrophin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20648
Homologene: 2331
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Zmynd8
Name: zinc finger, MYND-type containing 8
Synonyms: ZMYND8, 2010005I16Rik, 1110013E22Rik, 3632413B07Rik, RACK7, Prkcbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228880
HGNC: HGNC:9397
Homologene: 32679
Zfp710
Name: zinc finger protein 710
Synonyms: 5430400N05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209225
Homologene: 19625
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: Ctrn, citrin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50799
Homologene: 22800
Pafah2
Name: platelet-activating factor acetylhydrolase 2
Synonyms: 2310074E22Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100163
HGNC: HGNC:8579
Homologene: 37309
Usp5
Name: ubiquitin specific peptidase 5 (isopeptidase T)
Synonyms: Ucht
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22225
Homologene: 55758
Sec24d
Name: SEC24 homolog D, COPII coat complex component
Synonyms: 2310020L09Rik, LOC383951
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69608
Homologene: 40986
Xpo1
Name: exportin 1
Synonyms: Crm1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103573
Homologene: 2554
Dop1a
Name: DOP1 leucine zipper like protein A
Synonyms: Dopey1, B130005I07Rik, D9Ertd809e
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 320615
Homologene: 26645
Tet2
Name: tet methylcytosine dioxygenase 2
Synonyms: Ayu17-449, E130014J05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 214133
Homologene: 49498
Ccdc14
Name: coiled-coil domain containing 14
Synonyms: G630039H03Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239839
VEGA: 16
Homologene: 32549
Rsf1
Name: remodeling and spacing factor 1
Synonyms: 4832420A03Rik, p325, C030033M12Rik, Hbxap, XAP8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233532
Homologene: 41142
Mreg
Name: melanoregulin
Synonyms: Wdt2, LOC381269, dsu
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381269
Homologene: 9954
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Alsin, 9430073A21Rik, 3222402C23Rik, Als2cr6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Ep300
Name: E1A binding protein p300
Synonyms: p300, KAT3B
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Syne1
Name: spectrin repeat containing, nuclear envelope 1
Synonyms: SYNE-1, A330049M09Rik, enaptin165, nesprin-1, C130039F11Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64009
VEGA: 10
Homologene: 52329
Fzd3
Name: frizzled class receptor 3
Synonyms: D930050A07Rik, Fz3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 14365
HGNC: HGNC:4041
Homologene: 23004
Zdhhc6
Name: zinc finger, DHHC domain containing 6
Synonyms: 5930409M18Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66980
VEGA: 19
Homologene: 41487
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
H3f3a
Name: H3.3 histone A
Synonyms: H3-3a, H3.3A
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15078
Homologene: 134170
Or4m1
Name: olfactory receptor family 4 subfamily M member 1
Synonyms: MOR242-1, Olfr734, GA_x6K02T2PMLR-6013665-6012724
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 258658
Homologene: 51759
Pianp
Name: PILR alpha associated neural protein
Synonyms: C530028O21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319352
Homologene: 17799
Fam3b
Name: FAM3 metabolism regulating signaling molecule B
Synonyms: Pander, 9030624C24Rik, ORF9, D16Jhu19e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 52793
HGNC: HGNC:1253
Homologene: 10766
Muc16
Name: mucin 16
Synonyms: 1110008I14Rik, Gm21044, LOC385009
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73732
Homologene: 141193
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, Fath, 2310038E12Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
Dnaja3
Name: DnaJ heat shock protein family (Hsp40) member A3
Synonyms: 1200003J13Rik, Tid-1, 1810053A11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 83945
Homologene: 36170
Pja2
Name: praja ring finger ubiquitin ligase 2
Synonyms: Neurodap1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224938
Homologene: 32233
Rdx
Name: radixin
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19684
VEGA: 9
HGNC: HGNC:9944
Homologene: 37707
Zfp534
Name: zinc finger protein 534
Synonyms: Gm13159
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100503584
Homologene: 133076
Abhd8
Name: abhydrolase domain containing 8
Synonyms: 0910001L24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 64296
Homologene: 11188
Sppl2a
Name: signal peptide peptidase like 2A
Synonyms: 2010106G01Rik, C130089K23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66552
Homologene: 36411
Zfp750
Name: zinc finger protein 750
Synonyms: A030007D23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319530
Homologene: 36423
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, Slc9a10, spermNHE
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208169
Homologene: 19505
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Taf5l
Name: TATA-box binding protein associated factor 5 like
Synonyms: 1110005N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102162
Homologene: 8676
Aste1
Name: asteroid homolog 1
Synonyms: 1100001A21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66595
Homologene: 130666
Vwf
Name: Von Willebrand factor
Synonyms: 6820430P06Rik, B130011O06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Poln
Name: DNA polymerase N
Synonyms: POL4P
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 272158
Homologene: 131253
Adcy2
Name: adenylate cyclase 2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 210044
VEGA: 13
HGNC: HGNC:233
Homologene: 75133
Nox3
Name: NADPH oxidase 3
Synonyms: het, nmf250
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224480
HGNC: HGNC:7890
Homologene: 49435
Ihh
Name: Indian hedgehog
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16147
HGNC: HGNC:5956
Homologene: 22586
Nanos3
Name: nanos C2HC-type zinc finger 3
Synonyms: nos3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244551
Homologene: 65856
Pramel25
Name: PRAME like 25
Synonyms: MGC:91194, Gm13023
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 194227
Homologene: 103830
Bsn
Name: bassoon
Synonyms: presynaptic cytomatrix protein
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12217
HGNC: HGNC:1117
Homologene: 31161
Ifi206
Name: interferon activated gene 206
Synonyms: Gm4955, Pyblhin-C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 102639543
HGNC: HGNC:5395
Homologene: 115929
Actc1
Name: actin, alpha, cardiac muscle 1
Synonyms: alphac-actin, Actc-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11464
HGNC: HGNC:143
Homologene: 68446
Mical2
Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
Synonyms: 5330438E18Rik, Micalcl, 4921517J23Rik, Ebitein1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320878
Homologene: 8760
Fam98c
Name: family with sequence similarity 98, member C
Synonyms: B230110F21Rik, 1110006G06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73833
Homologene: 45483
Zmynd10
Name: zinc finger, MYND domain containing 10
Synonyms: Blu
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 114602
Homologene: 9293
Serpinb9
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9
Synonyms: Spi6, ovalbumin, PI-9
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20723
HGNC: HGNC:8955
Homologene: 37888
Bag6
Name: BCL2-associated athanogene 6
Synonyms: D17H6S52E, 2410045D21Rik, G3, Scythe, Bat3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224727
Homologene: 3409
Cenpj
Name: centromere protein J
Synonyms: Sas4, 4932437H03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219103
Homologene: 10204
Clca3a1
Name: chloride channel accessory 3A1
Synonyms: Clca1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12722
HGNC: HGNC:2017
Homologene: 77224
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241633
Homologene: 133162
Vmn2r124
Name: vomeronasal 2, receptor 124
Synonyms: Gm7196, Vmn2r-ps113
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 637021
Homologene: 115024
Cep250
Name: centrosomal protein 250
Synonyms: B230210E21Rik, Cep2, Inmp
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Vps16
Name: VSP16 CORVET/HOPS core subunit
Synonyms: 1810074M16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 80743
Homologene: 7116
Bivm
Name: basic, immunoglobulin-like variable motif containing
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 246229
Homologene: 9783
Abca7
Name: ATP-binding cassette, sub-family A member 7
Synonyms: Abc51
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 27403
HGNC: HGNC:37
Homologene: 22783
Dcxr
Name: dicarbonyl L-xylulose reductase
Synonyms: 1810027P18Rik, 0610038K04Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 67880
Homologene: 22964
Rnf146
Name: ring finger protein 146
Synonyms: Iduna, 2610509H23Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68031
Homologene: 12227
Pals1
Name: protein associated with LIN7 1, MAGUK family member
Synonyms: Mpp5, Pals1, 3830420B02Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56217
VEGA: 12
Homologene: 9512
Krtap12-1
Name: keratin associated protein 12-1
Synonyms: D10Jhu14e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16694
VEGA: 10
Homologene: 135687
Or8k18
Name: olfactory receptor family 8 subfamily K member 18
Synonyms: Olfr1049, MOR187-1, GA_x6K02T2Q125-47735396-47734470
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 259018
Homologene: 77387
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 44,128,789 bp
  • A to G, chromosome 1 at 59,180,550 bp
  • T to C, chromosome 1 at 72,192,057 bp
  • T to C, chromosome 1 at 74,946,339 bp
  • A to T, chromosome 1 at 173,471,456 bp
  • T to C, chromosome 1 at 180,803,095 bp
  • T to A, chromosome 2 at 86,255,678 bp
  • T to C, chromosome 2 at 114,050,465 bp
  • T to C, chromosome 2 at 126,392,830 bp
  • A to G, chromosome 2 at 126,923,473 bp
  • A to G, chromosome 2 at 130,424,399 bp
  • T to C, chromosome 2 at 154,380,936 bp
  • C to T, chromosome 2 at 155,970,122 bp
  • A to T, chromosome 2 at 165,858,138 bp
  • A to G, chromosome 3 at 123,294,161 bp
  • A to T, chromosome 3 at 133,469,613 bp
  • G to A, chromosome 3 at 144,758,034 bp
  • C to T, chromosome 4 at 134,419,970 bp
  • T to A, chromosome 4 at 143,793,608 bp
  • T to A, chromosome 4 at 147,675,625 bp
  • G to A, chromosome 5 at 34,014,314 bp
  • A to C, chromosome 5 at 41,788,923 bp
  • A to T, chromosome 6 at 6,109,987 bp
  • A to T, chromosome 6 at 124,823,451 bp
  • A to G, chromosome 6 at 125,000,695 bp
  • T to C, chromosome 6 at 125,642,730 bp
  • G to T, chromosome 7 at 28,894,504 bp
  • A to T, chromosome 7 at 29,154,690 bp
  • C to T, chromosome 7 at 80,081,374 bp
  • G to GACGGCGGCT, chromosome 7 at 97,579,909 bp
  • A to C, chromosome 7 at 112,271,382 bp
  • G to A, chromosome 8 at 45,009,841 bp
  • G to T, chromosome 8 at 71,461,745 bp
  • A to T, chromosome 8 at 84,176,451 bp
  • G to A, chromosome 8 at 124,003,275 bp
  • T to C, chromosome 9 at 18,647,582 bp
  • T to A, chromosome 9 at 52,064,879 bp
  • T to C, chromosome 9 at 86,513,155 bp
  • T to A, chromosome 9 at 105,396,709 bp
  • T to C, chromosome 9 at 107,549,127 bp
  • T to C, chromosome 9 at 108,116,150 bp
  • T to C, chromosome 10 at 5,108,556 bp
  • A to G, chromosome 10 at 29,347,543 bp
  • C to A, chromosome 10 at 77,720,789 bp
  • T to C, chromosome 10 at 80,002,518 bp
  • A to G, chromosome 11 at 23,285,058 bp
  • T to G, chromosome 11 at 118,046,178 bp
  • A to T, chromosome 11 at 120,726,546 bp
  • T to C, chromosome 11 at 121,513,848 bp
  • A to G, chromosome 12 at 78,797,058 bp
  • T to A, chromosome 13 at 33,006,703 bp
  • C to T, chromosome 13 at 68,625,808 bp
  • A to G, chromosome 14 at 50,320,757 bp
  • T to A, chromosome 14 at 56,542,862 bp
  • T to A, chromosome 14 at 65,212,177 bp
  • T to C, chromosome 14 at 103,843,092 bp
  • T to A, chromosome 15 at 81,649,745 bp
  • C to T, chromosome 16 at 4,702,300 bp
  • G to A, chromosome 16 at 34,706,789 bp
  • T to C, chromosome 16 at 45,580,127 bp
  • A to G, chromosome 16 at 97,501,000 bp
  • T to G, chromosome 17 at 3,669,861 bp
  • G to T, chromosome 17 at 18,074,177 bp
  • T to A, chromosome 17 at 35,144,712 bp
  • T to C, chromosome 17 at 64,309,475 bp
  • A to G, chromosome 19 at 29,301,062 bp
  • A to T, chromosome 19 at 55,313,248 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9128 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068927-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.