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Strain Name:
C57BL/6J-MtgxR9128Btlr/Mmmh
Stock Number:
068927-MU
Citation ID:
RRID:MMRRC_068927-MU
Other Names:
R9128 (G1)
Major Collection:

Strain Information

Ednrb
Name: endothelin receptor type B
Synonyms: ETb, Sox10m1, ETR-b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 13618
VEGA: 14
HGNC: HGNC:3180
Homologene: 89
Snta1
Name: syntrophin, acidic 1
Synonyms: alpha1-syntrophin, Snt1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20648
Homologene: 2331
Zmynd8
Name: zinc finger, MYND-type containing 8
Synonyms: 1110013E22Rik, 2010005I16Rik, ZMYND8, RACK7, 3632413B07Rik, Prkcbp1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228880
HGNC: HGNC:9397
Homologene: 32679
Zfp710
Name: zinc finger protein 710
Synonyms: 5430400N05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 209225
Homologene: 19625
Jak2
Name: Janus kinase 2
Synonyms: C81284
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16452
VEGA: 19
HGNC: HGNC:6192
Homologene: 21033
Slc25a13
Name: solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
Synonyms: Ctrn, citrin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50799
Homologene: 22800
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 44,128,789 bp
  • A to G, chromosome 1 at 59,180,550 bp
  • T to C, chromosome 1 at 72,192,057 bp
  • T to C, chromosome 1 at 74,946,339 bp
  • A to T, chromosome 1 at 173,471,456 bp
  • T to C, chromosome 1 at 180,803,095 bp
  • T to A, chromosome 2 at 86,255,678 bp
  • T to C, chromosome 2 at 114,050,465 bp
  • T to C, chromosome 2 at 126,392,830 bp
  • A to G, chromosome 2 at 126,923,473 bp
  • A to G, chromosome 2 at 130,424,399 bp
  • T to C, chromosome 2 at 154,380,936 bp
  • C to T, chromosome 2 at 155,970,122 bp
  • A to T, chromosome 2 at 165,858,138 bp
  • A to G, chromosome 3 at 123,294,161 bp
  • A to T, chromosome 3 at 133,469,613 bp
  • G to A, chromosome 3 at 144,758,034 bp
  • C to T, chromosome 4 at 134,419,970 bp
  • T to A, chromosome 4 at 143,793,608 bp
  • T to A, chromosome 4 at 147,675,625 bp
  • G to A, chromosome 5 at 34,014,314 bp
  • A to C, chromosome 5 at 41,788,923 bp
  • A to T, chromosome 6 at 6,109,987 bp
  • A to T, chromosome 6 at 124,823,451 bp
  • A to G, chromosome 6 at 125,000,695 bp
  • T to C, chromosome 6 at 125,642,730 bp
  • G to T, chromosome 7 at 28,894,504 bp
  • A to T, chromosome 7 at 29,154,690 bp
  • C to T, chromosome 7 at 80,081,374 bp
  • G to GACGGCGGCT, chromosome 7 at 97,579,909 bp
  • A to C, chromosome 7 at 112,271,382 bp
  • G to A, chromosome 8 at 45,009,841 bp
  • G to T, chromosome 8 at 71,461,745 bp
  • A to T, chromosome 8 at 84,176,451 bp
  • G to A, chromosome 8 at 124,003,275 bp
  • T to C, chromosome 9 at 18,647,582 bp
  • T to A, chromosome 9 at 52,064,879 bp
  • T to C, chromosome 9 at 86,513,155 bp
  • T to A, chromosome 9 at 105,396,709 bp
  • T to C, chromosome 9 at 107,549,127 bp
  • T to C, chromosome 9 at 108,116,150 bp
  • T to C, chromosome 10 at 5,108,556 bp
  • A to G, chromosome 10 at 29,347,543 bp
  • C to A, chromosome 10 at 77,720,789 bp
  • T to C, chromosome 10 at 80,002,518 bp
  • A to G, chromosome 11 at 23,285,058 bp
  • T to G, chromosome 11 at 118,046,178 bp
  • A to T, chromosome 11 at 120,726,546 bp
  • T to C, chromosome 11 at 121,513,848 bp
  • A to G, chromosome 12 at 78,797,058 bp
  • T to A, chromosome 13 at 33,006,703 bp
  • C to T, chromosome 13 at 68,625,808 bp
  • A to G, chromosome 14 at 50,320,757 bp
  • T to A, chromosome 14 at 56,542,862 bp
  • T to A, chromosome 14 at 65,212,177 bp
  • T to C, chromosome 14 at 103,843,092 bp
  • T to A, chromosome 15 at 81,649,745 bp
  • C to T, chromosome 16 at 4,702,300 bp
  • G to A, chromosome 16 at 34,706,789 bp
  • T to C, chromosome 16 at 45,580,127 bp
  • A to G, chromosome 16 at 97,501,000 bp
  • T to G, chromosome 17 at 3,669,861 bp
  • G to T, chromosome 17 at 18,074,177 bp
  • T to A, chromosome 17 at 35,144,712 bp
  • T to C, chromosome 17 at 64,309,475 bp
  • A to G, chromosome 19 at 29,301,062 bp
  • A to T, chromosome 19 at 55,313,248 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9128 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068927-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.