Strain Name:
C57BL/6J-MtgxR9242Btlr/Mmmh
Stock Number:
068988-MU
Citation ID:
RRID:MMRRC_068988-MU
Other Names:
R9242 (G1)
Major Collection:

Strain Information

Inpp5a
Name: inositol polyphosphate-5-phosphatase A
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212111
HGNC: HGNC:6076
Homologene: 4045
Sox10
Name: SRY (sex determining region Y)-box 10
Synonyms: gt, Sox21
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20665
VEGA: 15
Homologene: 5055
Agpat4
Name: 1-acylglycerol-3-phosphate O-acyltransferase 4
Synonyms: 1500003P24Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68262
Homologene: 69293
Helz
Name: helicase with zinc finger domain
Synonyms: 9430093I07Rik, 3110078M01Rik, 9630002H22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78455
Homologene: 8918
Cdk5rap2
Name: CDK5 regulatory subunit associated protein 2
Synonyms: 2900018K03Rik, an
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 214444
Homologene: 49533
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Unk
Name: unkempt family zinc finger
Synonyms: Zc3h5, B230379M23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217331
Homologene: 18194
Heatr1
Name: HEAT repeat containing 1
Synonyms: B130016L12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217995
VEGA: 13
Homologene: 34562
Emc2
Name: ER membrane protein complex subunit 2
Synonyms: 4921531G14Rik, Ttc35
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66736
VEGA: 15
Homologene: 8785
Lpin2
Name: lipin 2
Synonyms: 2610511G02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64898
Homologene: 8769
Tomm70a
Name: translocase of outer mitochondrial membrane 70A
Synonyms: 2610044B22Rik, Tom70, D16Ium22, Tomm70a, D16Wsu109e, D16Ium22e
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 28185
VEGA: 16
Homologene: 40112
Ackr3
Name: atypical chemokine receptor 3
Synonyms: Rdc1, Cxcr7, Cmkor1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12778
Homologene: 22419
Rcor1
Name: REST corepressor 1
Synonyms: D12Wsu95e, 6720480E22Rik, Rocr1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217864
Homologene: 32246
Chrdl2
Name: chordin-like 2
Synonyms: Chl2, 1810022C01Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 69121
Homologene: 128795
Fbl
Name: fibrillarin
Synonyms: RNU3IP1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14113
HGNC: HGNC:3599
Homologene: 1099
Carm1
Name: coactivator-associated arginine methyltransferase 1
Synonyms: Prmt4, m9Bei
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 59035
Homologene: 10990
Cand2
Name: cullin associated and neddylation dissociated 2 (putative)
Synonyms: Tp120b, 2210404G23Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67088
Homologene: 41657
Nceh1
Name: neutral cholesterol ester hydrolase 1
Synonyms: CPO-BP, mKIAA1363, B230106I24Rik, Aadacl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320024
Homologene: 23251
Lrp3
Name: low density lipoprotein receptor-related protein 3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 435965
HGNC: HGNC:6695
Homologene: 1745
Capg
Name: capping actin protein, gelsolin like
Synonyms: gCap39, mbh1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12332
HGNC: HGNC:1474
Homologene: 37523
Abcb4
Name: ATP-binding cassette, sub-family B member 4
Synonyms: Pgy-2, Mdr2, mdr-2, Pgy2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18670
HGNC: HGNC:45
Homologene: 136368
Ush2a
Name: usherin
Synonyms: Ushrn, A930037M10Rik, MUSH2A, LOC269160, A930011D15Rik, LOC381317, Ush2a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Lamc3
Name: laminin gamma 3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 23928
HGNC: HGNC:6494
Homologene: 21222
Impg1
Name: interphotoreceptor matrix proteoglycan 1
Synonyms: SPACR, A930015H12Rik, IMP150
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 63859
HGNC: HGNC:6055
Homologene: 1201
Ccr6
Name: C-C motif chemokine receptor 6
Synonyms: Cmkbr6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12458
VEGA: 17
HGNC: HGNC:1607
Homologene: 3214
Madd
Name: MAP-kinase activating death domain
Synonyms: 9630059K23Rik, Rab3 GEP
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228355
HGNC: HGNC:6766
Homologene: 14249
Ptchd4
Name: patched domain containing 4
Synonyms: 3110082D06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627626
VEGA: 17
Homologene: 78322
Wdpcp
Name: WD repeat containing planar cell polarity effector
Synonyms: homoloc-13, AV249152
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216560
Homologene: 9299
Gzmm
Name: granzyme M (lymphocyte met-ase 1)
Synonyms: Lmet1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16904
HGNC: HGNC:4712
Homologene: 21099
Gcc1
Name: golgi coiled coil 1
Synonyms: 4932417P04Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 74375
Homologene: 11567
Atrnl1
Name: attractin like 1
Synonyms: Alp
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226255
VEGA: 19
Homologene: 45809
Or5ae2
Name: olfactory receptor family 5 subfamily AE member 2
Synonyms: Olfr291, MOR254-2, GA_x6K02T2NHDJ-11231385-11230438
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258410
Homologene: 83130
Slc6a15
Name: solute carrier family 6 (neurotransmitter transporter), member 15
Synonyms: v7-3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103098
VEGA: 10
Homologene: 18163
Ampd1
Name: adenosine monophosphate deaminase 1
Synonyms: Ampd-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229665
HGNC: HGNC:468
Homologene: 20
Or5b96
Name: olfactory receptor family 5 subfamily B member 96
Synonyms: MOR202-2, GA_x6K02T2RE5P-3220047-3219130, Olfr1446
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258699
HGNC: HGNC:8324
Homologene: 74233
Wbp2nl
Name: WBP2 N-terminal like
Synonyms: PAWP, 4930521I23Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 74716
VEGA: 15
Homologene: 17633
Slc6a13
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 13
Synonyms: Gabt3, Gat2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14412
Homologene: 9592
Fktn
Name: fukutin
Synonyms: Fukutin, Fcmd
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 246179
HGNC: HGNC:3622
Homologene: 31402
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 636808
Homologene: 43974
Ptpru
Name: protein tyrosine phosphatase receptor type U
Synonyms: RPTPlambda, Ptprl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Synonyms: Dusg, MTP1, FPN1, Ol5, Pcm, Slc11a3, ferroportin1, metal transporting protein 1, IREG1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53945
Homologene: 40959
Tpi1
Name: triosephosphate isomerase 1
Synonyms: Tpi-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21991
Homologene: 128432
Dync1i1
Name: dynein cytoplasmic 1 intermediate chain 1
Synonyms: IC74, DIC, Dncic1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 13426
HGNC: HGNC:2963
Homologene: 68398
Inmt
Name: indolethylamine N-methyltransferase
Synonyms: Temt
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21743
HGNC: HGNC:6069
Homologene: 81752
D17H6S53E
Name: DNA segment, Chr 17, human D6S53E
Synonyms: NG34
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 114585
Homologene: 75155
Slc35f6
Name: solute carrier family 35, member F6
Synonyms: Tango9, 5730478O19Rik, p40, 4930471M23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 74919
Homologene: 9896
Vmn1r159
Name: vomeronasal 1 receptor 159
Synonyms: Gm16507
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 670857
Homologene: 104166
Esrra
Name: estrogen related receptor, alpha
Synonyms: Estrra, ERRalpha, Err1, Nr3b1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 26379
HGNC: HGNC:3471
Homologene: 20941
Tor4a
Name: torsin family 4, member A
Synonyms: A830007P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227612
Homologene: 17140
Ctsd
Name: cathepsin D
Synonyms: CatD, CD
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13033
HGNC: HGNC:2529
Homologene: 55616
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 45,910,969 bp
  • G to T, chromosome 1 at 90,214,836 bp
  • A to G, chromosome 1 at 116,292,379 bp
  • G to T, chromosome 1 at 188,633,590 bp
  • A to G, chromosome 2 at 25,195,525 bp
  • A to G, chromosome 2 at 31,898,311 bp
  • G to A, chromosome 2 at 91,143,604 bp
  • G to T, chromosome 2 at 158,435,466 bp
  • C to A, chromosome 3 at 27,239,628 bp
  • C to T, chromosome 3 at 103,091,620 bp
  • G to A, chromosome 4 at 53,734,854 bp
  • T to C, chromosome 4 at 70,337,346 bp
  • C to T, chromosome 4 at 131,803,030 bp
  • C to A, chromosome 5 at 8,899,677 bp
  • G to T, chromosome 5 at 30,648,066 bp
  • G to T, chromosome 5 at 94,303,142 bp
  • A to G, chromosome 6 at 5,769,706 bp
  • T to A, chromosome 6 at 28,420,376 bp
  • C to T, chromosome 6 at 55,173,285 bp
  • C to T, chromosome 6 at 72,555,886 bp
  • C to G, chromosome 6 at 115,791,962 bp
  • T to A, chromosome 6 at 121,318,269 bp
  • T to C, chromosome 6 at 124,814,175 bp
  • T to A, chromosome 7 at 22,843,487 bp
  • T to C, chromosome 7 at 28,177,195 bp
  • C to T, chromosome 7 at 35,202,509 bp
  • A to T, chromosome 7 at 84,856,878 bp
  • C to T, chromosome 7 at 100,006,536 bp
  • C to T, chromosome 7 at 139,481,718 bp
  • T to C, chromosome 7 at 142,383,543 bp
  • C to T, chromosome 9 at 21,583,054 bp
  • T to A, chromosome 9 at 80,381,782 bp
  • A to T, chromosome 10 at 79,694,520 bp
  • T to A, chromosome 10 at 103,393,545 bp
  • A to G, chromosome 11 at 21,885,040 bp
  • T to C, chromosome 11 at 107,632,327 bp
  • T to C, chromosome 11 at 116,049,358 bp
  • T to A, chromosome 12 at 111,109,794 bp
  • G to A, chromosome 13 at 12,433,925 bp
  • T to C, chromosome 15 at 43,495,243 bp
  • T to C, chromosome 15 at 79,156,440 bp
  • T to C, chromosome 15 at 82,308,547 bp
  • T to A, chromosome 16 at 57,138,020 bp
  • A to G, chromosome 17 at 8,256,133 bp
  • G to T, chromosome 17 at 12,210,299 bp
  • G to T, chromosome 17 at 35,127,560 bp
  • A to T, chromosome 17 at 42,316,713 bp
  • A to G, chromosome 17 at 71,246,971 bp
  • A to G, chromosome 19 at 6,912,495 bp
  • T to A, chromosome 19 at 12,890,625 bp
  • A to G, chromosome 19 at 57,657,228 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9242 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068988-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.