Strain Name:
C57BL/6J-MtgxR9143Btlr/Mmmh
Stock Number:
069014-MU
Citation ID:
RRID:MMRRC_069014-MU
Other Names:
R9143 (G1)
Major Collection:

Strain Information

Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Synonyms: XT-1, Xtrp1, Gabt1, Gat1, Gabt, GAT-1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232333
Homologene: 2290
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: C330012K04Rik, GalNAc-T10, Galnt9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171212
Homologene: 14924
Atl3
Name: atlastin GTPase 3
Synonyms: 5730596K20Rik, 4633402C03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 109168
VEGA: 19
Homologene: 9149
Lrrc59
Name: leucine rich repeat containing 59
Synonyms: C78668
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 98238
Homologene: 10229
Skap2
Name: src family associated phosphoprotein 2
Synonyms: Saps, 2610021A10Rik, SKAP-HOM, RA70, mSKAP55R
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54353
Homologene: 2919
Usp19
Name: ubiquitin specific peptidase 19
Synonyms: 8430421I07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71472
Homologene: 41730
Arid2
Name: AT-rich interaction domain 2
Synonyms: zipzap/p200, 1700124K17Rik, 4432409D24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77044
Homologene: 14601
Top2a
Name: topoisomerase (DNA) II alpha
Synonyms: DNA Topoisomerase II alpha, Top-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21973
Homologene: 830
Ccnt1
Name: cyclin T1
Synonyms: 2810478G24Rik, CycT1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12455
HGNC: HGNC:1599
Homologene: 947
Clec16a
Name: C-type lectin domain family 16, member A
Synonyms: 4932416N17Rik, curt
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 74374
Homologene: 71019
Tonsl
Name: tonsoku-like, DNA repair protein
Synonyms: 2810439M11Rik, Nfkbil2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72749
HGNC: HGNC:7801
Homologene: 22754
Dsp
Name: desmoplakin
Synonyms: 5730453H04Rik, DP, rul, 2300002E22Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 109620
HGNC: HGNC:3052
Homologene: 37922
Zzz3
Name: zinc finger, ZZ domain containing 3
Synonyms: 6430567E01Rik, 3110065C23Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 108946
Homologene: 9182
Mcf2l
Name: mcf.2 transforming sequence-like
Synonyms: C130040G20Rik, Dbs
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17207
Homologene: 11804
Sv2a
Name: synaptic vesicle glycoprotein 2a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 64051
Homologene: 32237
Il20rb
Name: interleukin 20 receptor beta
Synonyms: LOC213208, Il20R2, Fndc6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 213208
HGNC: HGNC:6004
Homologene: 86034
Tmem131l
Name: transmembrane 131 like
Synonyms: D930015E06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229473
Homologene: 9057
Stxbp1
Name: syntaxin binding protein 1
Synonyms: nsec1, Sxtbp1, Munc-18a, Unc18h, Munc18-1, N-sec1, Rb-sec1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20910
Homologene: 2382
Btbd16
Name: BTB domain containing 16
Synonyms: E330040A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 330660
Homologene: 77327
Cubn
Name: cubilin
Synonyms: D2Wsu88e, intrinsic factor-cobalamin receptor
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 65969
HGNC: HGNC:2548
Homologene: 37434
Pld1
Name: phospholipase D1
Synonyms: Pld1b, Pld1a
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18805
HGNC: HGNC:9067
Homologene: 116234
Nuak1
Name: NUAK family, SNF1-like kinase, 1
Synonyms: B230104P22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 77976
Homologene: 8896
Cngb3
Name: cyclic nucleotide gated channel beta 3
Synonyms: Cngbeta2, CNG6, CCNC2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 30952
HGNC: HGNC:2153
Homologene: 40908
9830107B12Rik
Name: RIKEN cDNA 9830107B12 gene
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328829
VEGA: 17
Homologene: 136361
Tigd2
Name: tigger transposable element derived 2
Synonyms: 3632410O17Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68140
Homologene: 129603
F830045P16Rik
Name: RIKEN cDNA F830045P16 gene
Synonyms: Sirpb3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228592
Homologene: 136180
Lipg
Name: lipase, endothelial
Synonyms: EL, 3110013K01Rik, mEDL, endothelial lipase
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16891
VEGA: 18
HGNC: HGNC:6623
Homologene: 21218
Spag17
Name: sperm associated antigen 17
Synonyms: PF6, 4931427F14Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74362
Homologene: 52601
Jade2
Name: jade family PHD finger 2
Synonyms: 1200017K05Rik, Phf15
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76901
Homologene: 9082
Or8g19
Name: olfactory receptor family 8 subfamily G member 19
Synonyms: MTPCR56, MOR171-6, GA_x6K02T2KYVW-1037-120, GA_x6K02T2PVTD-32841223-32842158, Olfr242, Olfr27
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258826
VEGA: 9
HGNC: HGNC:8484
Homologene: 110610
Col15a1
Name: collagen, type XV, alpha 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12819
HGNC: HGNC:2192
Homologene: 1396
Ces1d
Name: carboxylesterase 1D
Synonyms: TGH, Ces3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104158
HGNC: HGNC:1863
Homologene: 35606
Nin
Name: ninein
Synonyms: 3110068G20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18080
Homologene: 40632
Nfil3
Name: nuclear factor, interleukin 3, regulated
Synonyms: E4BP4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18030
HGNC: HGNC:7787
Homologene: 3928
Susd5
Name: sushi domain containing 5
Synonyms: LOC382111
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382111
VEGA: 9
Homologene: 19526
Insl5
Name: insulin-like 5
Synonyms: relaxin/insulin-like factor 2, RIF2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 23919
HGNC: HGNC:6088
Homologene: 48350
Or8b47
Name: olfactory receptor family 8 subfamily B member 47
Synonyms: GA_x6K02T2PVTD-32247224-32248163, MOR165-1, GA_x6K02T2PVTD-32223906-32224841, Olfr911, Olfr909, MOR166-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258873
VEGA: 9
Homologene: 74148
E330034G19Rik
Name: RIKEN cDNA E330034G19 gene
Synonyms: ZPAC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 105418
Hace1
Name: HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Synonyms: A730034A22Rik, 1700042J16Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 209462
Homologene: 10807
Vta1
Name: vesicle (multivesicular body) trafficking 1
Synonyms: 1110001D18Rik, 1110059P08Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66201
Homologene: 6473
Rcvrn
Name: recoverin
Synonyms: guanylate cyclase activator, S-modulin, cancer associated retinopathy protein
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19674
HGNC: HGNC:9937
Homologene: 2177
Krtap10-34
Name: keratin associated protein 10-34
Synonyms: Gm19668
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 100503388
Homologene: 115744
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 2 at 13,332,465 bp (GRCm38)
  • A to G, chromosome 2 at 32,798,145 bp (GRCm38)
  • T to C, chromosome 2 at 129,474,582 bp (GRCm38)
  • A to G, chromosome 3 at 28,078,494 bp (GRCm38)
  • A to G, chromosome 3 at 83,934,913 bp (GRCm38)
  • T to C, chromosome 3 at 96,190,667 bp (GRCm38)
  • C to T, chromosome 3 at 100,027,590 bp (GRCm38)
  • T to C, chromosome 3 at 152,458,271 bp (GRCm38)
  • T to A, chromosome 4 at 19,375,190 bp (GRCm38)
  • G to C, chromosome 4 at 47,288,200 bp (GRCm38)
  • C to A, chromosome 4 at 103,026,644 bp (GRCm38)
  • T to C, chromosome 6 at 51,908,429 bp (GRCm38)
  • T to A, chromosome 6 at 59,211,325 bp (GRCm38)
  • G to T, chromosome 6 at 114,315,542 bp (GRCm38)
  • C to T, chromosome 7 at 130,815,786 bp (GRCm38)
  • A to G, chromosome 8 at 13,012,883 bp (GRCm38)
  • T to A, chromosome 8 at 93,186,079 bp (GRCm38)
  • A to T, chromosome 9 at 38,516,621 bp (GRCm38)
  • A to T, chromosome 9 at 39,144,426 bp (GRCm38)
  • A to G, chromosome 9 at 100,474,883 bp (GRCm38)
  • T to G, chromosome 9 at 108,498,199 bp (GRCm38)
  • A to T, chromosome 9 at 114,095,811 bp (GRCm38)
  • T to C, chromosome 10 at 14,676,032 bp (GRCm38)
  • T to A, chromosome 10 at 45,686,668 bp (GRCm38)
  • T to C, chromosome 10 at 77,799,126 bp (GRCm38)
  • C to T, chromosome 10 at 84,378,087 bp (GRCm38)
  • T to C, chromosome 11 at 51,825,103 bp (GRCm38)
  • C to T, chromosome 11 at 57,721,320 bp (GRCm38)
  • T to C, chromosome 11 at 67,700,064 bp (GRCm38)
  • T to A, chromosome 11 at 94,634,630 bp (GRCm38)
  • T to A, chromosome 11 at 99,009,879 bp (GRCm38)
  • A to G, chromosome 12 at 70,090,575 bp (GRCm38)
  • T to A, chromosome 13 at 13,661,165 bp (GRCm38)
  • C to A, chromosome 13 at 38,193,361 bp (GRCm38)
  • A to G, chromosome 13 at 52,967,756 bp (GRCm38)
  • A to T, chromosome 14 at 24,296,936 bp (GRCm38)
  • T to C, chromosome 15 at 76,630,624 bp (GRCm38)
  • A to G, chromosome 15 at 96,361,834 bp (GRCm38)
  • G to A, chromosome 15 at 98,543,807 bp (GRCm38)
  • C to A, chromosome 16 at 10,611,100 bp (GRCm38)
  • T to C, chromosome 17 at 48,145,434 bp (GRCm38)
  • T to C, chromosome 18 at 74,954,201 bp (GRCm38)
  • T to C, chromosome 19 at 7,532,043 bp (GRCm38)
  • G to T, chromosome 19 at 61,120,340 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9143 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069014-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.