Strain Name:
C57BL/6J-MtgxR9192Btlr/Mmmh
Stock Number:
069037-MU
Citation ID:
RRID:MMRRC_069037-MU
Other Names:
R9192 (G1)
Major Collection:

Strain Information

Lhx6
Name: LIM homeobox protein 6
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16874
Homologene: 7401
Rps6kb1
Name: ribosomal protein S6 kinase, polypeptide 1
Synonyms: 2610318I15Rik, p70s6k, p70/85s6k, p70S6K1, S6K1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72508
Homologene: 81703
E2f7
Name: E2F transcription factor 7
Synonyms: E2F7, A630014C11Rik, D10Ertd739e
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52679
Homologene: 18685
Tnrc6a
Name: trinucleotide repeat containing 6a
Synonyms: CAGH26, Tnrc6, D130023A07Rik, 3110054G10Rik, 2010321I05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233833
Homologene: 41399
Kansl1
Name: KAT8 regulatory NSL complex subunit 1
Synonyms: 1700081L11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76719
Homologene: 9140
Baz1b
Name: bromodomain adjacent to zinc finger domain, 1B
Synonyms: WSTF, Wbscr9
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22385
HGNC: HGNC:961
Homologene: 22651
Kdm2b
Name: lysine (K)-specific demethylase 2B
Synonyms: Jhdm1b, Cxxc2, Fbxl10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 30841
Homologene: 13069
Akap13
Name: A kinase anchor protein 13
Synonyms: PROTO-LB, Ht31, 1700026G02Rik, PROTO-LBC, 5730522G15Rik, AKAP-Lbc, 5830460E08Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75547
HGNC: HGNC:371
Homologene: 4903
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, Estm14, Tle4l, C230057C06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21885
Homologene: 21058
Ctbp1
Name: C-terminal binding protein 1
Synonyms: D5H4S115E, BARS, CtBP1-S, CtBP3/BARS, D5H4S115, CtBP1-L, D4S115h
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13016
HGNC: HGNC:2494
Homologene: 1015
Herc1
Name: HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
Synonyms: D130015N03Rik, 2810449H11Rik, tbl
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235439
HGNC: HGNC:4867
Homologene: 31207
Dars1
Name: aspartyl-tRNA synthetase 1
Synonyms: 5730439G15Rik, Dars
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226414
HGNC: HGNC:2678
Homologene: 1032
Tuba1c
Name: tubulin, alpha 1C
Synonyms: M[a]6, Tuba6
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22146
VEGA: 15
Homologene: 69045
Angptl4
Name: angiopoietin-like 4
Synonyms: FIAF, HFARP, NG27, BK89
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57875
Homologene: 10755
Vav2
Name: vav 2 oncogene
Synonyms: 2810040F13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22325
Homologene: 2530
Psmd2
Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
Synonyms: TEG-190, Tex190, 9430095H01Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 21762
HGNC: HGNC:9559
Homologene: 2101
Zfp644
Name: zinc finger protein 644
Synonyms: 1110068L01Rik, BM-005, Zep-2, D5Ertd689e
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 52397
Homologene: 12971
Osbpl10
Name: oxysterol binding protein-like 10
Synonyms: 4933433D06Rik, C820004B04Rik, OPR-10
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74486
Homologene: 69240
Serinc4
Name: serine incorporator 4
Synonyms: A930015D22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 574418
Homologene: 67424
Stk32b
Name: serine/threonine kinase 32B
Synonyms: Stk32, YANK2, STKG6, 2510009F08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 64293
Homologene: 48654
Rnf26rt
Name: ring finger protein 26, retrotransposed
Synonyms: Gm9008
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 668155
Nphs2
Name: nephrosis 2, podocin
Synonyms: podocin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 170484
Homologene: 22826
Sall3
Name: spalt like transcription factor 3
Synonyms: Msal, Msal-1, B130022O04Rik, Spalt, Salt
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20689
VEGA: 18
Homologene: 18142
Nos3
Name: nitric oxide synthase 3, endothelial cell
Synonyms: 2310065A03Rik, ecNOS, Nos-3, eNOS
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18127
HGNC: HGNC:7876
Homologene: 504
Lama2
Name: laminin, alpha 2
Synonyms: mer, merosin
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16773
HGNC: HGNC:6482
Homologene: 37306
Tns2
Name: tensin 2
Synonyms: nep, Tenc1, nph
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Mocos
Name: molybdenum cofactor sulfurase
Synonyms: 1110018O12Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68591
VEGA: 18
Homologene: 9931
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Otop1
Name: otopetrin 1
Synonyms: A530025J20Rik, tlt
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21906
Homologene: 35244
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Pico, Acz
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 26875
Homologene: 69111
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: D12Ertd777e, Cpfl8, dice, 6820443O06Rik, nesprin-2, syne-2, Nesp2g, diminished cone electroretinogram
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 319565
Homologene: 56700
Kmt5b
Name: lysine methyltransferase 5B
Synonyms: Suv420h1, C630029K18Rik, Suv4-20h1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225888
Homologene: 32351
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241516
Homologene: 110349
Slc27a2
Name: solute carrier family 27 (fatty acid transporter), member 2
Synonyms: VLCS, ACSVL1, Vlac, FATP2, FATP2, Vlacs
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26458
Homologene: 37830
Fscb
Name: fibrous sheath CABYR binding protein
Synonyms: EG623046
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 623046
VEGA: 12
Homologene: 136275
Vmn2r5
Name: vomeronasal 2, receptor 5
Synonyms: EG667060
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 667060
Spag16
Name: sperm associated antigen 16
Synonyms: 4930585K05Rik, 4930524F24Rik, 4921511D23Rik, Wdr29, Pf20
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 66722
Homologene: 11572
Pygl
Name: liver glycogen phosphorylase
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 110095
HGNC: HGNC:9725
Homologene: 84371
Slc6a7
Name: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms: Prot
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240332
VEGA: 18
Homologene: 8592
Gucy2e
Name: guanylate cyclase 2e
Synonyms: ROS-GC1, GC1, GC-E
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14919
HGNC: HGNC:4689
Homologene: 55442
Zswim8
Name: zinc finger SWIM-type containing 8
Synonyms: 4832404P21Rik, 2310021P13Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 268721
VEGA: 14
Homologene: 34313
Tnrc18
Name: trinucleotide repeat containing 18
Synonyms: EG381742, Zfp469
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231861
Homologene: 45603
Stat6
Name: signal transducer and activator of transcription 6
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 20852
Homologene: 2373
Zfp954
Name: zinc finger protein 954
Synonyms: 5730403M16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232853
Homologene: 129792
Tmem79
Name: transmembrane protein 79
Synonyms: 2310074C17Rik, mattrin, Matt, 2310042N02Rik, ma
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71913
Homologene: 11492
Or2ag16
Name: olfactory receptor family 2 subfamily AG member 16
Synonyms: Olfr698, MOR283-3, GA_x6K02T2PBJ9-9130754-9129519
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258595
Homologene: 133598
Slc5a7
Name: solute carrier family 5 (choline transporter), member 7
Synonyms: CHT1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 63993
VEGA: 17
Homologene: 32516
Klhdc10
Name: kelch domain containing 10
Synonyms: 2410127E18Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 76788
Homologene: 15267
Sv2c
Name: synaptic vesicle glycoprotein 2c
Synonyms: 4930527L09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75209
Homologene: 57152
Tas2r121
Name: taste receptor, type 2, member 121
Synonyms: mGR21, mT2r48, Tas2r21, T2R21
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387349
Homologene: 41542
Mettl15
Name: methyltransferase like 15
Synonyms: 0610027B03Rik, Mett5d1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 76894
Homologene: 12661
Hcar2
Name: hydroxycarboxylic acid receptor 2
Synonyms: Gpr109a, HM74, Gpr109b, Pumag, PUMA-G, Niacr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80885
Homologene: 4391
Ovca2
Name: candidate tumor suppressor in ovarian cancer 2
Synonyms: 9030414M07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246257
Homologene: 6086
BC035947
Name: cDNA sequence BC035947
Type: Gene
Species: Mouse
Chromosome: 1
Rhoq
Name: ras homolog family member Q
Synonyms: TC10, Arhq
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 104215
Homologene: 22704
Or51i2
Name: olfactory receptor family 51 subfamily I member 2
Synonyms: Olfr641, MOR13-3, GA_x6K02T2PBJ9-6773690-6774628
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259075
Homologene: 17489
Pcdhga1
Name: protocadherin gamma subfamily A, 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93709
HGNC: HGNC:8696
Homologene: 56824
Or4x13
Name: olfactory receptor family 4 subfamily X member 13
Synonyms: Olfr1274-ps, GA_x6K02T2Q125-51676372-51677301, MOR228-5, MOR228-4, Olfr1274
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258330
Homologene: 133650
Pcdha11
Name: protocadherin alpha 11
Synonyms: A830022B16Rik, Cnr7, Crnr7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
Pcdhga8
Name: protocadherin gamma subfamily A, 8
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93716
HGNC: HGNC:8706
Homologene: 57162
Trav7-5
Name: T cell receptor alpha variable 7-5
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 630061
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 69,923,848 bp (GRCm38)
  • A to T, chromosome 1 at 78,499,240 bp (GRCm38)
  • T to C, chromosome 1 at 128,372,152 bp (GRCm38)
  • G to A, chromosome 1 at 156,310,816 bp (GRCm38)
  • A to T, chromosome 2 at 27,282,382 bp (GRCm38)
  • A to T, chromosome 2 at 36,091,133 bp (GRCm38)
  • T to C, chromosome 2 at 52,313,835 bp (GRCm38)
  • A to G, chromosome 2 at 76,914,911 bp (GRCm38)
  • A to G, chromosome 2 at 82,987,500 bp (GRCm38)
  • C to A, chromosome 2 at 90,401,372 bp (GRCm38)
  • A to T, chromosome 2 at 109,274,465 bp (GRCm38)
  • G to A, chromosome 2 at 121,456,769 bp (GRCm38)
  • T to A, chromosome 2 at 126,587,887 bp (GRCm38)
  • G to T, chromosome 3 at 64,491,517 bp (GRCm38)
  • A to T, chromosome 3 at 88,333,457 bp (GRCm38)
  • G to T, chromosome 4 at 72,118,516 bp (GRCm38)
  • A to G, chromosome 5 at 14,540,190 bp (GRCm38)
  • A to G, chromosome 5 at 24,377,613 bp (GRCm38)
  • T to C, chromosome 5 at 33,250,989 bp (GRCm38)
  • A to G, chromosome 5 at 37,629,000 bp (GRCm38)
  • T to C, chromosome 5 at 38,287,930 bp (GRCm38)
  • G to C, chromosome 5 at 106,637,963 bp (GRCm38)
  • T to A, chromosome 5 at 122,932,616 bp (GRCm38)
  • A to T, chromosome 5 at 123,865,291 bp (GRCm38)
  • T to G, chromosome 5 at 135,210,794 bp (GRCm38)
  • C to A, chromosome 5 at 142,787,847 bp (GRCm38)
  • T to A, chromosome 6 at 30,449,500 bp (GRCm38)
  • T to C, chromosome 6 at 76,496,583 bp (GRCm38)
  • T to C, chromosome 6 at 132,700,529 bp (GRCm38)
  • C to T, chromosome 7 at 7,115,934 bp (GRCm38)
  • T to A, chromosome 7 at 75,704,501 bp (GRCm38)
  • A to T, chromosome 7 at 104,040,668 bp (GRCm38)
  • A to G, chromosome 7 at 106,753,223 bp (GRCm38)
  • C to A, chromosome 7 at 123,189,953 bp (GRCm38)
  • G to A, chromosome 9 at 66,414,131 bp (GRCm38)
  • T to C, chromosome 9 at 115,167,226 bp (GRCm38)
  • C to T, chromosome 10 at 27,328,185 bp (GRCm38)
  • G to T, chromosome 10 at 110,763,990 bp (GRCm38)
  • G to A, chromosome 10 at 127,657,610 bp (GRCm38)
  • A to T, chromosome 11 at 69,236,477 bp (GRCm38)
  • A to G, chromosome 11 at 75,178,036 bp (GRCm38)
  • T to C, chromosome 11 at 86,513,555 bp (GRCm38)
  • A to T, chromosome 11 at 104,336,316 bp (GRCm38)
  • A to C, chromosome 12 at 64,474,116 bp (GRCm38)
  • A to G, chromosome 12 at 70,197,048 bp (GRCm38)
  • T to A, chromosome 12 at 76,109,929 bp (GRCm38)
  • T to A, chromosome 13 at 96,088,247 bp (GRCm38)
  • C to T, chromosome 14 at 20,719,520 bp (GRCm38)
  • C to G, chromosome 14 at 53,531,158 bp (GRCm38)
  • T to A, chromosome 15 at 99,037,856 bp (GRCm38)
  • C to A, chromosome 15 at 102,112,981 bp (GRCm38)
  • T to A, chromosome 16 at 20,654,662 bp (GRCm38)
  • C to T, chromosome 17 at 33,781,311 bp (GRCm38)
  • T to C, chromosome 17 at 54,287,361 bp (GRCm38)
  • A to T, chromosome 17 at 86,996,977 bp (GRCm38)
  • A to G, chromosome 18 at 24,679,537 bp (GRCm38)
  • A to G, chromosome 18 at 37,007,474 bp (GRCm38)
  • A to T, chromosome 18 at 37,726,110 bp (GRCm38)
  • A to G, chromosome 18 at 37,840,031 bp (GRCm38)
  • A to G, chromosome 18 at 61,000,577 bp (GRCm38)
  • G to A, chromosome 18 at 80,973,909 bp (GRCm38)
  • T to C, chromosome 19 at 3,804,442 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9192 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069037-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.