Strain Name:
C57BL/6J-MtgxR9333Btlr/Mmmh
Stock Number:
069145-MU
Citation ID:
RRID:MMRRC_069145-MU
Other Names:
R9333 (G1)
Major Collection:

Strain Information

Hcn2
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 2
Synonyms: HAC1, trls
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15166
HGNC: HGNC:4846
Homologene: 31022
Gtf2i
Name: general transcription factor II I
Synonyms: BAP-135, 6030441I21Rik, TFII-I
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14886
HGNC: HGNC:4659
Homologene: 7748
Arhgap39
Name: Rho GTPase activating protein 39
Synonyms: D15Wsu169e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223666
Homologene: 27825
Myh10
Name: myosin, heavy polypeptide 10, non-muscle
Synonyms: nonmuscle myosin heavy chain IIB, SMemb, NMHC-B, nonmuscle myosin heavy chain II-B, Myhn-2, 5730504C04Rik, myosin IIB, Fltn, Myhn2, Fltn, NMHC II-B, Myosin IIB, 9330167F11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77579
HGNC: HGNC:7568
Homologene: 55941
Tcf7l2
Name: transcription factor 7 like 2, T cell specific, HMG box
Synonyms: mTcf-4E, TCF4E, TCF4B, mTcf-4B, Tcf-4, Tcf4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 21416
Homologene: 7564
Arfgef1
Name: ADP ribosylation factor guanine nucleotide exchange factor 1
Synonyms: BIG1, P200, ARFGEP1, D730028O18Rik, D130059B05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 211673
Homologene: 4687
Prmt3
Name: protein arginine N-methyltransferase 3
Synonyms: 2410018A17Rik, 2010005E20Rik, Hrmt1l3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71974
Homologene: 24255
Fanci
Name: Fanconi anemia, complementation group I
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 208836
Homologene: 49530
Gm14403
Name: predicted gene 14403
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 433520
Rpl28
Name: ribosomal protein L28
Synonyms: D7Wsu21e
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19943
Homologene: 768
Spg11
Name: SPG11, spatacsin vesicle trafficking associated
Synonyms: spastic paraplegia 11, 6030465E24Rik, C530005A01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214585
Homologene: 41614
D6Wsu163e
Name: DNA segment, Chr 6, Wayne State University 163, expressed
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28040
HGNC: HGNC:1184
Homologene: 10685
Usp39
Name: ubiquitin specific peptidase 39
Synonyms: D6Wsu157e, CGI-21, SAD1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 28035
Homologene: 13183
Dolpp1
Name: dolichyl pyrophosphate phosphatase 1
Synonyms: 0610011H20Rik, LSFR2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57170
Homologene: 10663
Prcp
Name: prolylcarboxypeptidase (angiotensinase C)
Synonyms: 2510048K03Rik, 2610104A14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72461
HGNC: HGNC:9344
Homologene: 55867
Rag2
Name: recombination activating gene 2
Synonyms: Rag-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19374
HGNC: HGNC:9832
Homologene: 7507
Kctd12
Name: potassium channel tetramerisation domain containing 12
Synonyms: Pfet1, Pfetin
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239217
Homologene: 16316
Baiap3
Name: BAI1-associated protein 3
Synonyms: LOC381076
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 545192
HGNC: HGNC:948
Homologene: 20844
Grm2
Name: glutamate receptor, metabotropic 2
Synonyms: 4930441L02Rik, Gprc1b, mGluR2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 108068
HGNC: HGNC:4594
Homologene: 20229
Ryr1
Name: ryanodine receptor 1, skeletal muscle
Synonyms: Ryr, skrr, calcium release channel isoform 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20190
Homologene: 68069
Orm3
Name: orosomucoid 3
Synonyms: Agp-3, Orm-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18407
Homologene: 130632
Rnpep
Name: arginyl aminopeptidase (aminopeptidase B)
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 215615
Homologene: 10628
Vmn2r26
Name: vomeronasal 2, receptor 26
Synonyms: V2r1b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56552
Homologene: 135915
Kremen2
Name: kringle containing transmembrane protein 2
Synonyms: Krm2, 2900054E04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73016
VEGA: 17
Homologene: 65132
4933427I04Rik
Name: Riken cDNA 4933427I04 gene
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 115489902
VEGA: 4
Aldoart1
Name: aldolase 1 A, retrogene 1
Synonyms: Aldoa-ps2, Aldo1-ps2, 4921524E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 353204
Homologene: 128442
Asb2
Name: ankyrin repeat and SOCS box-containing 2
Synonyms: 1110008E15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 65256
Homologene: 69202
Clcn4
Name: chloride channel, voltage-sensitive 4
Synonyms: Clcn4-2, Clc4-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12727
HGNC: HGNC:2022
Homologene: 68207
Mfsd10
Name: major facilitator superfamily domain containing 10
Synonyms: 0610009O03Rik, Tetran
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68294
Homologene: 871
Pgm2
Name: phosphoglucomutase 2
Synonyms: Pgm1, Pgm-1, 3230402E02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 66681
HGNC: HGNC:8906
Homologene: 6693
Or2ag16
Name: olfactory receptor family 2 subfamily AG member 16
Synonyms: GA_x6K02T2PBJ9-9130754-9129519, MOR283-3, Olfr698
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258595
Homologene: 133598
Atp8b3
Name: ATPase, class I, type 8B, member 3
Synonyms: 1700056N23Rik, 1700042F02Rik, SAPLT
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67331
VEGA: 10
Homologene: 19034
Fbxo39
Name: F-box protein 39
Synonyms: 1700010H23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 628100
Homologene: 15156
Fam217a
Name: family with sequence similarity 217, member A
Synonyms: 1700026J04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71864
VEGA: 13
Homologene: 82344
Ndufaf5
Name: NADH:ubiquinone oxidoreductase complex assembly factor 5
Synonyms: 2310003L22Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 69487
Homologene: 11474
Crbn
Name: cereblon
Synonyms: 2900045O07Rik, 2610203G15Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 58799
Homologene: 9461
Abraxas1
Name: BRCA1 A complex subunit
Synonyms: Fam175a, 5630400M01Rik, 3830405G04Rik, Ccdc98
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70681
Homologene: 16376
Hsd3b3
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
Synonyms: 9030618K22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15494
Homologene: 133013
Klra4
Name: killer cell lectin-like receptor, subfamily A, member 4
Synonyms: Ly49d, Chok, ly49r129
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16635
Homologene: 110821
Reep1
Name: receptor accessory protein 1
Synonyms: D6Ertd253e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 52250
Homologene: 41504
Fbxo4
Name: F-box protein 4
Synonyms: 1700096C12Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 106052
Homologene: 8134
Lmf2
Name: lipase maturation factor 2
Synonyms: Tmem153, Tmem112b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105847
VEGA: 15
Homologene: 11251
Mageb3
Name: MAGE family member B3
Synonyms: Smage3, Mage-b3, Mage-ps1, Mage-rs3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17147
Homologene: 137208
Vmn2r34
Name: vomeronasal 2, receptor 34
Synonyms: ENSMUSG00000070841
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042636
Homologene: 113703
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • C to A, chromosome 1 at 10,151,812 bp (GRCm38)
  • A to T, chromosome 1 at 135,264,124 bp (GRCm38)
  • T to A, chromosome 2 at 30,397,128 bp (GRCm38)
  • A to T, chromosome 2 at 101,630,407 bp (GRCm38)
  • A to T, chromosome 2 at 121,954,492 bp (GRCm38)
  • G to A, chromosome 2 at 122,101,763 bp (GRCm38)
  • A to G, chromosome 2 at 140,193,593 bp (GRCm38)
  • A to G, chromosome 2 at 177,509,126 bp (GRCm38)
  • T to C, chromosome 3 at 98,741,900 bp (GRCm38)
  • T to C, chromosome 4 at 63,356,291 bp (GRCm38)
  • C to T, chromosome 4 at 72,852,130 bp (GRCm38)
  • G to T, chromosome 4 at 123,860,623 bp (GRCm38)
  • A to G, chromosome 5 at 34,635,083 bp (GRCm38)
  • C to A, chromosome 5 at 64,105,757 bp (GRCm38)
  • T to C, chromosome 5 at 100,812,073 bp (GRCm38)
  • C to T, chromosome 5 at 134,242,986 bp (GRCm38)
  • A to G, chromosome 6 at 71,795,214 bp (GRCm38)
  • T to C, chromosome 6 at 72,337,727 bp (GRCm38)
  • T to C, chromosome 6 at 106,800,023 bp (GRCm38)
  • C to T, chromosome 6 at 124,026,050 bp (GRCm38)
  • A to G, chromosome 6 at 126,975,133 bp (GRCm38)
  • T to A, chromosome 6 at 130,044,117 bp (GRCm38)
  • T to C, chromosome 7 at 4,793,080 bp (GRCm38)
  • T to A, chromosome 7 at 7,289,193 bp (GRCm38)
  • C to T, chromosome 7 at 7,672,368 bp (GRCm38)
  • A to C, chromosome 7 at 29,074,789 bp (GRCm38)
  • T to G, chromosome 7 at 49,806,560 bp (GRCm38)
  • T to C, chromosome 7 at 79,417,846 bp (GRCm38)
  • T to C, chromosome 7 at 92,928,686 bp (GRCm38)
  • T to C, chromosome 7 at 106,752,575 bp (GRCm38)
  • C to A, chromosome 9 at 106,648,217 bp (GRCm38)
  • T to A, chromosome 10 at 79,726,157 bp (GRCm38)
  • T to C, chromosome 10 at 80,524,346 bp (GRCm38)
  • A to C, chromosome 11 at 68,790,154 bp (GRCm38)
  • A to T, chromosome 11 at 72,317,523 bp (GRCm38)
  • G to A, chromosome 12 at 103,345,696 bp (GRCm38)
  • T to C, chromosome 13 at 34,916,893 bp (GRCm38)
  • T to C, chromosome 14 at 102,981,618 bp (GRCm38)
  • A to G, chromosome 15 at 3,969,020 bp (GRCm38)
  • C to T, chromosome 15 at 76,735,125 bp (GRCm38)
  • G to A, chromosome 15 at 89,355,374 bp (GRCm38)
  • T to A, chromosome 17 at 23,743,801 bp (GRCm38)
  • C to A, chromosome 17 at 25,248,702 bp (GRCm38)
  • C to A, chromosome 19 at 55,931,496 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9333 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069145-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.