Strain Name:
C57BL/6J-MtgxR9577Btlr/Mmmh
Stock Number:
069370-MU
Citation ID:
RRID:MMRRC_069370-MU
Other Names:
R9577 (G1)
Major Collection:

Strain Information

Kif3a
Name: kinesin family member 3A
Synonyms: Kns3, N-4 kinesin, Kif3, kinesin-II subunit, Kifl
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16568
HGNC: HGNC:6319
Homologene: 38266
Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: Todo, Gena 52, GENA 60, Dz, Cycn, Cyn, Obt, Mt, Whi, GENA 47, A730019I05Rik, Lda, Flo, Edy, WBE1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Ptprz1
Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
Synonyms: PTPzeta, DSD-1-PG, phosphacan, RPTPz, Ptprz, Ptpz, Rptpbeta, PTPbeta
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19283
HGNC: HGNC:9685
Homologene: 2136
Tm9sf4
Name: transmembrane 9 superfamily member 4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99237
Homologene: 21620
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: C130052G03Rik, LOC237877
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237877
Homologene: 32611
Fbxo42
Name: F-box protein 42
Synonyms: 6720460I06Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 213499
Homologene: 16234
Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
Synonyms: Centd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 212285
Homologene: 9064
Ube4b
Name: ubiquitination factor E4B
Synonyms: D4Bwg0973e, 4930551I19Rik, UFD2, Ufd2p, UFD2a, 4933406G05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 63958
Homologene: 107623
Dmxl2
Name: Dmx-like 2
Synonyms: E130119P06Rik, 6430411K14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235380
HGNC: HGNC:2938
Homologene: 41022
Brms1l
Name: breast cancer metastasis-suppressor 1-like
Synonyms: 0710008O11Rik, BRMS1, D12Ertd407e
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 52592
VEGA: 12
Homologene: 9123
Dennd1b
Name: DENN domain containing 1B
Synonyms: F730008N07Rik, 6820401H01Rik, 4930467M19Rik, 4632404N19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329260
Homologene: 11739
Tbc1d1
Name: TBC1 domain family, member 1
Synonyms: 1110062G02Rik, Nobq1, Nob1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 57915
Homologene: 56856
Trpm4
Name: transient receptor potential cation channel, subfamily M, member 4
Synonyms: TRPM4B, 1110030C19Rik, LTRPC4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68667
Homologene: 23033
Ccdc71
Name: coiled-coil domain containing 71
Synonyms: 2600016J21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72454
Homologene: 11288
Nxpe2
Name: neurexophilin and PC-esterase domain family, member 2
Synonyms: 4432416J03Rik, Fam55b
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 78252
Homologene: 87072
Itfg1
Name: integrin alpha FG-GAP repeat containing 1
Synonyms: 2310047C21Rik, D8Wsu49e
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71927
Homologene: 12423
Sdccag8
Name: serologically defined colon cancer antigen 8
Synonyms: 5730470G24Rik, 2700048G21Rik, CCCAP
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 76816
Homologene: 4839
Baz2b
Name: bromodomain adjacent to zinc finger domain, 2B
Synonyms: 5830435C13Rik, D2Ertd794e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 407823
HGNC: HGNC:963
Homologene: 8394
Kcnk2
Name: potassium channel, subfamily K, member 2
Synonyms: TREK-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16526
HGNC: HGNC:6277
Homologene: 7794
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: nmf112, 4930542A03Rik, USH1D, sals, ahl, bob, mdfw, nmf252, nmf181
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Spdye4b
Name: speedy/RINGO cell cycle regulator family, member E4B
Synonyms: 4933411G11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330228
Homologene: 138445
Ptpn13
Name: protein tyrosine phosphatase, non-receptor type 13
Synonyms: PTPL1, PTP-BL, Ptpri
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19249
HGNC: HGNC:9646
Homologene: 7909
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50791
Homologene: 8189
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: Dnahc9, D11Ertd686e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Btnl1
Name: butyrophilin-like 1
Synonyms: NG10, LOC240074, LOC240074, Btnl3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 100038862
Homologene: 103816
Trpm5
Name: transient receptor potential cation channel, subfamily M, member 5
Synonyms: Ltrpc5, Mtr1, 9430099A16Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56843
Homologene: 22818
Vipr1
Name: vasoactive intestinal peptide receptor 1
Synonyms: VIP-R1, VIP receptor subtype 1, VPAC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22354
Homologene: 3399
Gsdmc2
Name: gasdermin C2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 331063
HGNC: HGNC:7151
Homologene: 69487
Ankar
Name: ankyrin and armadillo repeat containing
Synonyms: 4932422E22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319695
Homologene: 85163
Shroom1
Name: shroom family member 1
Synonyms: Shrm1, Apx, 1300007L22Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71774
Homologene: 12411
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69700
Homologene: 43567
Kif14
Name: kinesin family member 14
Synonyms: N-3 kinesin, D1Ertd367e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381293
Homologene: 8916
Abca14
Name: ATP-binding cassette, sub-family A member 14
Synonyms: 1700110B15Rik, 4930539G24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67928
Homologene: 86128
Prss36
Name: serine protease 36
Synonyms: polyserase-2, C330007D15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77613
Homologene: 18303
Psg23
Name: pregnancy-specific beta-1-glycoprotein 23
Synonyms: 1620401C02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56868
HGNC: HGNC:1819
Homologene: 110989
Lmntd2
Name: lamin tail domain containing 2
Synonyms: 1600016N20Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72000
Homologene: 104159
Tbx18
Name: T-box18
Synonyms: 2810012F10Rik, 2810404D13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76365
Homologene: 11384
Lman2l
Name: lectin, mannose-binding 2-like
Synonyms: A630028F14Rik, VIP36-like
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 214895
Homologene: 57125
Fam83e
Name: family with sequence similarity 83, member E
Synonyms: 4930403C10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 73813
Homologene: 9791
Zc3h6
Name: zinc finger CCCH type containing 6
Synonyms: 4631426G04Rik, 4833425H18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 78751
Homologene: 35328
Fmn1
Name: formin 1
Synonyms: Fmn, formin-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14260
HGNC: HGNC:3768
Homologene: 121778
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231396
Homologene: 128251
B3gntl1
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
Synonyms: 6030413G23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 210004
Homologene: 14460
Myb
Name: myeloblastosis oncogene
Synonyms: c-myb
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17863
HGNC: HGNC:7545
Homologene: 31311
Zer1
Name: zyg-11 related, cell cycle regulator
Synonyms: Zyg11bl, C230075L19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227693
Homologene: 4621
Or1j1
Name: olfactory receptor family 1 subfamily J member 1
Synonyms: MOR136-14, Olfr3, GA_x6K02T2NLDC-33507606-33506665, Y71
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18328
HGNC: HGNC:8208
Homologene: 66579
2700062C07Rik
Name: RIKEN cDNA 2700062C07 gene
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68046
VEGA: 18
Homologene: 12230
Card9
Name: caspase recruitment domain family, member 9
Synonyms: LOC332579
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 332579
Homologene: 14150
Aipl1
Name: aryl hydrocarbon receptor-interacting protein-like 1
Synonyms: A930007I01Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 114230
HGNC: HGNC:359
Homologene: 22806
Gm6309
Name: predicted gene 6309
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622306
Homologene: 86127
Gnpda1
Name: glucosamine-6-phosphate deaminase 1
Synonyms: oscillin, Gnpi, glucose-6-phosphate isomerase, Gnp1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 26384
HGNC: HGNC:4417
Homologene: 38054
Or8g28
Name: olfactory receptor family 8 subfamily G member 28
Synonyms: GA_x6K02T2PVTD-32955932-32954982, MOR171-20, Olfr945
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258499
VEGA: 9
HGNC: HGNC:8484
Homologene: 133643
Mri1
Name: methylthioribose-1-phosphate isomerase 1
Synonyms: 2410018C20Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67873
Homologene: 7160
Pramel52-ps
Name: PRAME like 52, pseudogene
Synonyms: AA792892
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100554
Homologene: 133359
Pou4f3
Name: POU domain, class 4, transcription factor 3
Synonyms: Brn3c, Brn-3.1, Brn3.1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 18998
HGNC: HGNC:9220
Homologene: 2023
Bnip5
Name: BCL2 interacting protein 5
Synonyms: 4930539E08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 207819
Homologene: 52098
Pcdha12
Name: protocadherin alpha 12
Synonyms: Pcdha13, Crnr5, Cnr5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 192164
HGNC: HGNC:8667
Homologene: 135870
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 36,428,409 bp (GRCm38)
  • C to A, chromosome 1 at 72,681,908 bp (GRCm38)
  • T to C, chromosome 1 at 136,471,400 bp (GRCm38)
  • T to C, chromosome 1 at 139,090,458 bp (GRCm38)
  • T to A, chromosome 1 at 176,831,063 bp (GRCm38)
  • CAAA to CAA, chromosome 1 at 189,256,694 bp (GRCm38)
  • T to A, chromosome 2 at 26,352,332 bp (GRCm38)
  • T to C, chromosome 2 at 30,101,038 bp (GRCm38)
  • C to A, chromosome 2 at 36,812,555 bp (GRCm38)
  • T to C, chromosome 2 at 59,978,687 bp (GRCm38)
  • C to T, chromosome 2 at 113,364,125 bp (GRCm38)
  • T to A, chromosome 2 at 129,016,182 bp (GRCm38)
  • T to C, chromosome 2 at 153,195,374 bp (GRCm38)
  • A to G, chromosome 4 at 8,752,964 bp (GRCm38)
  • T to A, chromosome 4 at 141,180,432 bp (GRCm38)
  • A to G, chromosome 4 at 149,383,774 bp (GRCm38)
  • C to T, chromosome 5 at 20,609,284 bp (GRCm38)
  • A to T, chromosome 5 at 62,611,717 bp (GRCm38)
  • T to A, chromosome 5 at 64,316,356 bp (GRCm38)
  • T to C, chromosome 5 at 87,080,925 bp (GRCm38)
  • A to T, chromosome 5 at 94,383,946 bp (GRCm38)
  • C to A, chromosome 5 at 103,528,809 bp (GRCm38)
  • A to G, chromosome 5 at 143,196,300 bp (GRCm38)
  • T to C, chromosome 5 at 146,168,890 bp (GRCm38)
  • G to T, chromosome 6 at 23,002,203 bp (GRCm38)
  • A to T, chromosome 7 at 18,612,142 bp (GRCm38)
  • A to T, chromosome 7 at 45,305,008 bp (GRCm38)
  • G to T, chromosome 7 at 45,727,015 bp (GRCm38)
  • T to C, chromosome 7 at 120,211,545 bp (GRCm38)
  • T to C, chromosome 7 at 127,934,501 bp (GRCm38)
  • T to C, chromosome 7 at 141,211,077 bp (GRCm38)
  • A to G, chromosome 7 at 143,079,394 bp (GRCm38)
  • A to G, chromosome 8 at 84,256,300 bp (GRCm38)
  • A to G, chromosome 8 at 85,776,169 bp (GRCm38)
  • A to G, chromosome 9 at 39,258,441 bp (GRCm38)
  • G to A, chromosome 9 at 48,326,332 bp (GRCm38)
  • A to G, chromosome 9 at 54,416,380 bp (GRCm38)
  • A to G, chromosome 9 at 87,729,459 bp (GRCm38)
  • C to T, chromosome 9 at 108,463,273 bp (GRCm38)
  • G to A, chromosome 9 at 121,642,927 bp (GRCm38)
  • C to T, chromosome 10 at 21,154,713 bp (GRCm38)
  • A to G, chromosome 10 at 60,311,116 bp (GRCm38)
  • A to G, chromosome 11 at 53,466,785 bp (GRCm38)
  • T to C, chromosome 11 at 53,584,404 bp (GRCm38)
  • C to T, chromosome 11 at 65,976,521 bp (GRCm38)
  • C to T, chromosome 11 at 72,037,427 bp (GRCm38)
  • T to A, chromosome 11 at 80,114,170 bp (GRCm38)
  • T to C, chromosome 11 at 121,624,214 bp (GRCm38)
  • A to G, chromosome 12 at 55,860,091 bp (GRCm38)
  • T to A, chromosome 15 at 63,825,057 bp (GRCm38)
  • T to C, chromosome 15 at 71,965,746 bp (GRCm38)
  • A to T, chromosome 17 at 28,909,408 bp (GRCm38)
  • A to G, chromosome 17 at 34,384,361 bp (GRCm38)
  • G to T, chromosome 18 at 24,475,606 bp (GRCm38)
  • C to T, chromosome 18 at 37,022,073 bp (GRCm38)
  • T to C, chromosome 18 at 38,330,552 bp (GRCm38)
  • C to G, chromosome 18 at 42,395,498 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9577 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069370-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.