Strain Name:
C57BL/6J-MtgxR9625Btlr/Mmmh
Stock Number:
069418-MU
Citation ID:
RRID:MMRRC_069418-MU
Other Names:
R9625 (G1)
Major Collection:

Strain Information

Cd40
Name: CD40 antigen
Synonyms: p50, Bp50, Cd40, Tnfrsf5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21939
Homologene: 954
Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: RPTPkappa, PTPk
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Ncoa3
Name: nuclear receptor coactivator 3
Synonyms: TRAM-1, bHLHe42, KAT13B, RAC3, AIB1, TRAM1, pCIP, Src3, 2010305B15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17979
HGNC: HGNC:7670
Homologene: 4764
Rrp15
Name: ribosomal RNA processing 15 homolog
Synonyms: 5430437H21Rik, 2810430M08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67223
Homologene: 32293
Ptprg
Name: protein tyrosine phosphatase receptor type G
Synonyms: 5430405N12Rik, RPTPgamma
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Tom1l2
Name: target of myb1-like 2 (chicken)
Synonyms: 2900016I08Rik, A730055F12Rik, myb1-like protein 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216810
Homologene: 44901
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: 2810431N21Rik, PEPP2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109135
Homologene: 10377
Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: 4930431E10Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 75788
Homologene: 10712
Dhx16
Name: DEAH-box helicase 16
Synonyms: DEAH (Asp-Glu-Ala-His) box polypeptide 16, DBP2, 2410006N22Rik, Ddx16
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69192
HGNC: HGNC:2739
Homologene: 2658
Myo1d
Name: myosin ID
Synonyms: 9930104H07Rik, D11Ertd9e
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 338367
HGNC: HGNC:7598
Homologene: 45576
Abhd5
Name: abhydrolase domain containing 5
Synonyms: IECN5, 2010002J10Rik, NCIE2, 1300003D03Rik, CGI-58
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67469
Homologene: 41088
Fam171b
Name: family with sequence similarity 171, member B
Synonyms: D430039N05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241520
Homologene: 18462
Vps11
Name: VPS11, CORVET/HOPS core subunit
Synonyms: 1200011A11Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71732
VEGA: 9
Homologene: 6673
Cthrc1
Name: collagen triple helix repeat containing 1
Synonyms: 1110014B07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68588
Homologene: 16320
Adgre5
Name: adhesion G protein-coupled receptor E5
Synonyms: Cd97, EGF-TM7 receptor
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26364
Homologene: 8050
Kalrn
Name: kalirin, RhoGEF kinase
Synonyms: LOC224126, E530005C20Rik, 2210407G14Rik, Hapip
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 545156
HGNC: HGNC:4814
Homologene: 57160
Kdm2a
Name: lysine (K)-specific demethylase 2A
Synonyms: Cxxc8, Fbxl11, Jhdm1a, Fbl7, lalina, 5530401A10Rik, Gm4560
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225876
Homologene: 56564
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: KAT13A, bHLHe74, SRC-1, SRC-a/NCoA-1, steroid receptor coactivator-1, SRC1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Mthfd2l
Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
Synonyms: 1110019K23Rik, C630010D07Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665563
Homologene: 28295
Cfap46
Name: cilia and flagella associated protein 46
Synonyms: Ttc40, 9330101J02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212124
Efcab2
Name: EF-hand calcium binding domain 2
Synonyms: 1700073K01Rik, D830011E08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68226
Homologene: 12248
H2-K1
Name: histocompatibility 2, K1, K region
Synonyms: H-2K
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 14972
Homologene: 128352
Efhc1
Name: EF-hand domain (C-terminal) containing 1
Synonyms: mRib72-1, myoclonin1, 1700029F22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71877
Homologene: 10003
Ltbp1
Name: latent transforming growth factor beta binding protein 1
Synonyms: 9430031G15Rik, LTBP-1, b2b1000Clo, Ltbp1L
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268977
HGNC: HGNC:6714
Homologene: 522
Emilin2
Name: elastin microfibril interfacer 2
Synonyms: FOAP-10, basilin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 246707
VEGA: 17
Homologene: 36483
Ptpro
Name: protein tyrosine phosphatase receptor type O
Synonyms: D28, PTPROt, Ptpn15, PTP-oc, GLEPP1, PTP-U2, PTP-BK, PTP-phi
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Kif1a
Name: kinesin family member 1A
Synonyms: ATSV, N-3 kinesin, Kns1, LOC381283, C630002N23Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16560
HGNC: HGNC:888
Homologene: 99729
Nlrp14
Name: NLR family, pyrin domain containing 14
Synonyms: GC-LRR, 4921520L01Rik, Nalp14, Nalp-iota
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76858
Homologene: 18531
Cntnap4
Name: contactin associated protein-like 4
Synonyms: Caspr4, E130114F09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 170571
Homologene: 24912
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: X83337, ESTM15, 1810073P09Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Ceacam10
Name: CEA cell adhesion molecule 10
Synonyms: Cea10, Bgp3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26366
Lrrk1
Name: leucine-rich repeat kinase 1
Synonyms: D130026O16Rik, C230002E15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233328
Homologene: 23464
Hormad2
Name: HORMA domain containing 2
Synonyms: 4930529M09Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 75828
Homologene: 45130
Dcaf7
Name: DDB1 and CUL4 associated factor 7
Synonyms: 1700012F10Rik, 2610037L01Rik, Wdr68
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71833
Homologene: 55930
Adcyap1r1
Name: adenylate cyclase activating polypeptide 1 receptor 1
Synonyms: PAC1, 2900024I10Rik, PACAP1-R, PAC1R
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11517
HGNC: HGNC:242
Homologene: 870
Arhgef33
Name: Rho guanine nucleotide exchange factor 33
Synonyms: LOC381112, Gm941
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381112
VEGA: 17
Homologene: 55190
Nfe2l3
Name: nuclear factor, erythroid derived 2, like 3
Synonyms: Nrf3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 18025
HGNC: HGNC:7783
Homologene: 3168
Spata13
Name: spermatogenesis associated 13
Synonyms: ESTM11
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219140
Homologene: 19482
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238680
VEGA: 13
Homologene: 129602
Pcdhb17
Name: protocadherin beta 17
Synonyms: PcdhbQ, Pcdhb16
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93888
Homologene: 81881
4930432M17Rik
Name: RIKEN cDNA 4930432M17 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 619318
Fam98a
Name: family with sequence similarity 98, member A
Synonyms: 2810405J04Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72722
Homologene: 41042
Tex44
Name: testis expressed 44
Synonyms: 1700019O17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 71863
Homologene: 51874
Npb
Name: neuropeptide B
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 208990
Homologene: 102151
P2ry12
Name: purinergic receptor P2Y, G-protein coupled 12
Synonyms: P2Y12, 4921504D23Rik, 2900079B22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70839
Homologene: 11260
Phb2
Name: prohibitin 2
Synonyms: REA, Bcap37, Bap37, repressor of estrogen receptor activity
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12034
Homologene: 5263
Or51f1
Name: olfactory receptor family 51 subfamily F member 1
Synonyms: Olfr566, MOR14-7P, GA_x6K02T2PBJ9-5560696-5559746
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258168
Homologene: 133721
Hoxb1
Name: homeobox B1
Synonyms: Hox-2.9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15407
HGNC: HGNC:5111
Homologene: 1615
Gpr143
Name: G protein-coupled receptor 143
Synonyms: Oa1
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 18241
Homologene: 230
Asl
Name: argininosuccinate lyase
Synonyms: 2510006M18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109900
HGNC: HGNC:746
Homologene: 32
Nicn1
Name: nicolin 1
Synonyms: 1500032A17Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66257
Homologene: 11936
Gm3573
Name: predicted gene 3573
Type: Gene
Species: Mouse
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 20,979,514 bp (GRCm38)
  • T to C, chromosome 1 at 86,426,531 bp (GRCm38)
  • C to T, chromosome 1 at 93,073,044 bp (GRCm38)
  • C to T, chromosome 1 at 178,474,940 bp (GRCm38)
  • G to T, chromosome 1 at 186,721,521 bp (GRCm38)
  • A to T, chromosome 2 at 83,853,570 bp (GRCm38)
  • A to T, chromosome 2 at 165,063,141 bp (GRCm38)
  • G to A, chromosome 2 at 166,057,210 bp (GRCm38)
  • C to T, chromosome 2 at 177,475,997 bp (GRCm38)
  • G to A, chromosome 3 at 59,218,075 bp (GRCm38)
  • A to G, chromosome 3 at 121,671,384 bp (GRCm38)
  • A to G, chromosome 5 at 90,959,708 bp (GRCm38)
  • G to A, chromosome 5 at 130,018,852 bp (GRCm38)
  • A to G, chromosome 5 at 144,894,110 bp (GRCm38)
  • A to T, chromosome 6 at 51,457,945 bp (GRCm38)
  • A to T, chromosome 6 at 55,480,070 bp (GRCm38)
  • G to A, chromosome 6 at 124,714,011 bp (GRCm38)
  • G to T, chromosome 6 at 137,394,875 bp (GRCm38)
  • A to T, chromosome 6 at 140,426,527 bp (GRCm38)
  • A to G, chromosome 7 at 24,777,280 bp (GRCm38)
  • A to T, chromosome 7 at 66,259,918 bp (GRCm38)
  • C to T, chromosome 7 at 102,856,429 bp (GRCm38)
  • A to G, chromosome 7 at 107,182,962 bp (GRCm38)
  • C to T, chromosome 7 at 139,650,889 bp (GRCm38)
  • A to G, chromosome 8 at 83,724,029 bp (GRCm38)
  • T to C, chromosome 8 at 112,875,549 bp (GRCm38)
  • A to G, chromosome 9 at 44,354,441 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • A to G, chromosome 9 at 122,379,541 bp (GRCm38)
  • T to C, chromosome 10 at 28,586,010 bp (GRCm38)
  • G to A, chromosome 11 at 4,427,372 bp (GRCm38)
  • A to G, chromosome 11 at 60,270,451 bp (GRCm38)
  • C to A, chromosome 11 at 80,557,470 bp (GRCm38)
  • C to T, chromosome 11 at 96,365,984 bp (GRCm38)
  • T to G, chromosome 11 at 106,051,968 bp (GRCm38)
  • T to C, chromosome 11 at 120,608,549 bp (GRCm38)
  • T to A, chromosome 12 at 4,295,643 bp (GRCm38)
  • C to A, chromosome 13 at 49,100,969 bp (GRCm38)
  • A to T, chromosome 13 at 64,858,765 bp (GRCm38)
  • C to T, chromosome 14 at 12,152,027 bp (GRCm38)
  • T to C, chromosome 14 at 42,189,648 bp (GRCm38)
  • C to T, chromosome 14 at 60,706,900 bp (GRCm38)
  • T to C, chromosome 15 at 39,084,479 bp (GRCm38)
  • T to A, chromosome 16 at 34,028,827 bp (GRCm38)
  • G to A, chromosome 17 at 34,000,001 bp (GRCm38)
  • A to G, chromosome 17 at 35,882,521 bp (GRCm38)
  • A to G, chromosome 17 at 71,274,117 bp (GRCm38)
  • G to T, chromosome 17 at 75,179,162 bp (GRCm38)
  • A to G, chromosome 17 at 75,538,479 bp (GRCm38)
  • A to T, chromosome 17 at 80,347,278 bp (GRCm38)
  • T to A, chromosome 18 at 37,486,366 bp (GRCm38)
  • C to T, chromosome 19 at 4,343,113 bp (GRCm38)
  • GTTTTTT to GTTTTTTT, chromosome X at 152,795,631 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9625 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069418-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.