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Strain Name:
C57BL/6J-MtgxR9625Btlr/Mmmh
Stock Number:
069418-MU
Citation ID:
RRID:MMRRC_069418-MU
Other Names:
R9625 (G1)
Major Collection:

Strain Information

Cd40
Name: CD40 antigen
Synonyms: Cd40, Bp50, p50, Tnfrsf5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21939
Homologene: 954
Ptprk
Name: protein tyrosine phosphatase receptor type K
Synonyms: PTPk, RPTPkappa
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19272
VEGA: 10
HGNC: HGNC:9674
Homologene: 55693
Ncoa3
Name: nuclear receptor coactivator 3
Synonyms: pCIP, TRAM-1, AIB1, RAC3, TRAM1, Src3, 2010305B15Rik, KAT13B, bHLHe42
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17979
HGNC: HGNC:7670
Homologene: 4764
Rrp15
Name: ribosomal RNA processing 15 homolog
Synonyms: 5430437H21Rik, 2810430M08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67223
Homologene: 32293
Ptprg
Name: protein tyrosine phosphatase receptor type G
Synonyms: 5430405N12Rik, RPTPgamma
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19270
HGNC: HGNC:9671
Homologene: 2129
Tom1l2
Name: target of myb1-like 2 (chicken)
Synonyms: 2900016I08Rik, myb1-like protein 2, A730055F12Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216810
Homologene: 44901
Plekha5
Name: pleckstrin homology domain containing, family A member 5
Synonyms: PEPP2, 2810431N21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 109135
Homologene: 10377
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 20,979,514 bp (GRCm38)
  • T to C, chromosome 1 at 86,426,531 bp (GRCm38)
  • C to T, chromosome 1 at 93,073,044 bp (GRCm38)
  • C to T, chromosome 1 at 178,474,940 bp (GRCm38)
  • G to T, chromosome 1 at 186,721,521 bp (GRCm38)
  • A to T, chromosome 2 at 83,853,570 bp (GRCm38)
  • A to T, chromosome 2 at 165,063,141 bp (GRCm38)
  • G to A, chromosome 2 at 166,057,210 bp (GRCm38)
  • C to T, chromosome 2 at 177,475,997 bp (GRCm38)
  • G to A, chromosome 3 at 59,218,075 bp (GRCm38)
  • A to G, chromosome 3 at 121,671,384 bp (GRCm38)
  • A to G, chromosome 5 at 90,959,708 bp (GRCm38)
  • G to A, chromosome 5 at 130,018,852 bp (GRCm38)
  • A to G, chromosome 5 at 144,894,110 bp (GRCm38)
  • A to T, chromosome 6 at 51,457,945 bp (GRCm38)
  • A to T, chromosome 6 at 55,480,070 bp (GRCm38)
  • G to A, chromosome 6 at 124,714,011 bp (GRCm38)
  • G to T, chromosome 6 at 137,394,875 bp (GRCm38)
  • A to T, chromosome 6 at 140,426,527 bp (GRCm38)
  • A to G, chromosome 7 at 24,777,280 bp (GRCm38)
  • A to T, chromosome 7 at 66,259,918 bp (GRCm38)
  • C to T, chromosome 7 at 102,856,429 bp (GRCm38)
  • A to G, chromosome 7 at 107,182,962 bp (GRCm38)
  • C to T, chromosome 7 at 139,650,889 bp (GRCm38)
  • A to G, chromosome 8 at 83,724,029 bp (GRCm38)
  • T to C, chromosome 8 at 112,875,549 bp (GRCm38)
  • A to G, chromosome 9 at 44,354,441 bp (GRCm38)
  • C to T, chromosome 9 at 108,294,509 bp (GRCm38)
  • A to G, chromosome 9 at 122,379,541 bp (GRCm38)
  • T to C, chromosome 10 at 28,586,010 bp (GRCm38)
  • G to A, chromosome 11 at 4,427,372 bp (GRCm38)
  • A to G, chromosome 11 at 60,270,451 bp (GRCm38)
  • C to A, chromosome 11 at 80,557,470 bp (GRCm38)
  • C to T, chromosome 11 at 96,365,984 bp (GRCm38)
  • T to G, chromosome 11 at 106,051,968 bp (GRCm38)
  • T to C, chromosome 11 at 120,608,549 bp (GRCm38)
  • T to A, chromosome 12 at 4,295,643 bp (GRCm38)
  • C to A, chromosome 13 at 49,100,969 bp (GRCm38)
  • A to T, chromosome 13 at 64,858,765 bp (GRCm38)
  • C to T, chromosome 14 at 12,152,027 bp (GRCm38)
  • T to C, chromosome 14 at 42,189,648 bp (GRCm38)
  • C to T, chromosome 14 at 60,706,900 bp (GRCm38)
  • T to C, chromosome 15 at 39,084,479 bp (GRCm38)
  • T to A, chromosome 16 at 34,028,827 bp (GRCm38)
  • G to A, chromosome 17 at 34,000,001 bp (GRCm38)
  • A to G, chromosome 17 at 35,882,521 bp (GRCm38)
  • A to G, chromosome 17 at 71,274,117 bp (GRCm38)
  • G to T, chromosome 17 at 75,179,162 bp (GRCm38)
  • A to G, chromosome 17 at 75,538,479 bp (GRCm38)
  • A to T, chromosome 17 at 80,347,278 bp (GRCm38)
  • T to A, chromosome 18 at 37,486,366 bp (GRCm38)
  • C to T, chromosome 19 at 4,343,113 bp (GRCm38)
  • GTTTTTT to GTTTTTTT, chromosome X at 152,795,631 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain GQC Summary
The MMRRC Centers have developed a Strain GQC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC strains. For more information on whether data may be available, or to request genotyping for a strain of interest, please contact MMRRC_GeneticQC@med.unc.edu. Older strains may not have this information available.
Suggested Control Mice
Littermates of all relevant genotypes.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9625 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.


Disclaimer: If MMRRC Strain Genetic Quality Control (GQC; based on MiniMUGA genotyping and analysis) has been completed for this strain, the information might differ from the genetic background information provided by the submitter. MiniMUGA genetic analysis is done on a strain’s tissue samples taken when archived by or ordered from the assigned MMRRC Center.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069418-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.