Strain Name:
C57BL/6J-MtgxR9654Btlr/Mmmh
Stock Number:
069447-MU
Citation ID:
RRID:MMRRC_069447-MU
Other Names:
R9654 (G1)
Major Collection:

Strain Information

Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 9030227G01Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Tlr6
Name: toll-like receptor 6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21899
Homologene: 21223
Ltn1
Name: listerin E3 ubiquitin protein ligase 1
Synonyms: 4930528H02Rik, Listerin, Zfp294, Rnf160
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 78913
VEGA: 16
Homologene: 32272
Hsd17b4
Name: hydroxysteroid (17-beta) dehydrogenase 4
Synonyms: MFP2, Mfp-2, 17[b]-HSD, perMFE-2, multifunctional protein 2, MFE-2, D-bifunctional protein
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 15488
HGNC: HGNC:5213
Homologene: 358
Idh3a
Name: isocitrate dehydrogenase 3 (NAD+) alpha
Synonyms: 1500012E04Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 67834
VEGA: 9
HGNC: HGNC:5384
Homologene: 4037
Mcm5
Name: minichromosome maintenance complex component 5
Synonyms: mCD46, Cdc46, Mcmd5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17218
HGNC: HGNC:6948
Homologene: 4904
Heatr5a
Name: HEAT repeat containing 5A
Synonyms: D930036F22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320487
VEGA: 12
Homologene: 19635
Fkbp15
Name: FK506 binding protein 15
Synonyms: FKBP133, C430014M02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338355
Homologene: 28743
Amotl1
Name: angiomotin-like 1
Synonyms: 2310067L22Rik, 4932416D09Rik, JEAP, 2310010G08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75723
Homologene: 43977
Utp15
Name: UTP15 small subunit processome component
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105372
VEGA: 13
Homologene: 6629
Arl4c
Name: ADP-ribosylation factor-like 4C
Synonyms: A630084M22Rik, Arl7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 320982
HGNC: HGNC:698
Homologene: 4193
Bod1l
Name: biorientation of chromosomes in cell division 1-like
Synonyms: A230054D04Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 665775
Homologene: 45109
Abca17
Name: ATP-binding cassette, sub-family A member 17
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381072
Homologene: 86807
Zap70
Name: zeta-chain (TCR) associated protein kinase
Synonyms: TZK, ZAP-70, Srk
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22637
Homologene: 839
Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Synonyms: VR-OAC, VRL-2, VROAC, Trp12, OTRPC4, 0610033B08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 63873
Homologene: 11003
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Nus1
Name: NUS1 dehydrodolichyl diphosphate synthase subunit
Synonyms: 1600027K07Rik, D10Ertd438e, NgBR
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52014
Homologene: 12719
Hbs1l
Name: Hbs1-like (S. cerevisiae)
Synonyms: 2810035F15Rik, eRFS
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56422
VEGA: 10
HGNC: HGNC:4834
Homologene: 68525
Sugp1
Name: SURP and G patch domain containing 1
Synonyms: Sf4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70616
Homologene: 12360
Clmn
Name: calmin
Synonyms: 9330188N17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 94040
VEGA: 12
Homologene: 11683
Tmprss4
Name: transmembrane protease, serine 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 214523
Homologene: 80930
Dock8
Name: dedicator of cytokinesis 8
Synonyms: 1200017A24Rik, 5830472H07Rik, A130095G14Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76088
VEGA: 19
Homologene: 52414
Pgk2
Name: phosphoglycerate kinase 2
Synonyms: Pgk-2, Tcp-2, Tcp-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18663
VEGA: 17
HGNC: HGNC:8898
Homologene: 57138
Fhip1a
Name: FHF complex subunit HOOK interacting protein 1A
Synonyms: Fam160a1, 9930021J17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229488
Homologene: 85149
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, Dnahcl1, Dnahc17, 2810003K23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Dnah14
Name: dynein, axonemal, heavy chain 14
Synonyms: LOC381311, Gm980, A230079K17Rik, Dnahc14
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240960
HGNC: HGNC:2945
Homologene: 90078
Dnah3
Name: dynein, axonemal, heavy chain 3
Synonyms: Dnahc3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381917
HGNC: HGNC:2949
Homologene: 19674
Npy4r
Name: neuropeptide Y receptor Y4
Synonyms: Ppyr1, NYYR-D, Y4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19065
VEGA: 14
Homologene: 38119
Btnl6
Name: butyrophilin-like 6
Synonyms: NG13, Gm6519
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 624681
Homologene: 106849
Arhgef25
Name: Rho guanine nucleotide exchange factor 25
Synonyms: GEFT, D10Ertd610e, 2410008H17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52666
VEGA: 10
Homologene: 32691
Map6
Name: microtubule-associated protein 6
Synonyms: F-STOP, Mtap6, 2810411E12Rik, STOP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17760
HGNC: HGNC:6868
Homologene: 7850
Myh2
Name: myosin, heavy polypeptide 2, skeletal muscle, adult
Synonyms: Myhs-f, MyHC-IIa, MHC2A, Myhsf1, Myhs-f1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17882
HGNC: HGNC:7572
Homologene: 23019
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99696
Homologene: 129859
4930407I10Rik
Name: RIKEN cDNA 4930407I10 gene
Synonyms: LOC328573
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328573
VEGA: 15
Homologene: 130065
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628444
Homologene: 129683
Or2w4
Name: olfactory receptor family 2 subfamily W member 4
Synonyms: Olfr1363-ps1, GA_x6K02T2QHY8-11628399-11628868, GA_x6K02T2QHY8-11617756-11618682, Olfr1362, MOR256-8
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258739
Homologene: 105885
Rhbdf1
Name: rhomboid 5 homolog 1
Synonyms: Dist, Egfr-rs, Dist1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13650
Homologene: 32085
Itih1
Name: inter-alpha trypsin inhibitor, heavy chain 1
Synonyms: Intin1, Itih-1, inter-alpha (globulin) inhibitor, H1 polypeptide
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16424
HGNC: HGNC:6166
Homologene: 1667
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: PXR2, Pex2, 1700016J08Rik, TRIP8b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 58869
Homologene: 9562
Ccdc154
Name: coiled-coil domain containing 154
Synonyms: LOC207209, ntl
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 207209
Homologene: 19361
Aoc1l1
Name: amine oxidase copper containing 1-like 1
Synonyms: Doxl2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243376
HGNC: HGNC:80
Homologene: 19443
Rsph6a
Name: radial spoke head 6 homolog A (Chlamydomonas)
Synonyms: Rshl1, RSP4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 83434
Homologene: 36476
H2-Q6
Name: histocompatibility 2, Q region locus 6
Synonyms: 0610037M15Rik, Qa6, Qa-6, H-2Q6
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 110557
Homologene: 128352
Or5k17
Name: olfactory receptor family 5 subfamily K member 17
Synonyms: GA_x54KRFPKG5P-55145984-55145034, MOR184-4, Olfr181
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 259001
Homologene: 74112
Mr1
Name: major histocompatibility complex, class I-related
Synonyms: MR1, H2ls
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 15064
HGNC: HGNC:4975
Homologene: 123981
Ncoa4
Name: nuclear receptor coactivator 4
Synonyms: 4432406M01Rik, 1110034E15Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 27057
HGNC: HGNC:7671
Homologene: 38052
Cacng8
Name: calcium channel, voltage-dependent, gamma subunit 8
Synonyms: TARP gamma 8
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81905
Homologene: 12894
Alx1
Name: ALX homeobox 1
Synonyms: Cart1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216285
HGNC: HGNC:1494
Homologene: 5075
Sult2a6
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
Synonyms: Gm6957
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629219
Homologene: 37741
Tmem178b
Name: transmembrane protein 178B
Synonyms: Gm5567, A930009E05Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 434008
Homologene: 86704
Or4c11b
Name: olfactory receptor family 4 subfamily C member 11B
Synonyms: GA_x6K02T2Q125-50268830-50269753, Olfr1201, MOR230-2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258897
Homologene: 81567
Pcdha11
Name: protocadherin alpha 11
Synonyms: Cnr7, A830022B16Rik, Crnr7
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12942
HGNC: HGNC:8665
Homologene: 75095
Or10ag55-ps1
Name: olfactory receptor family 10 subfamily AG member 55, pseudogene 1
Synonyms: Olfr1117-ps1, MOR264-27_p, GA_x6K02T2Q125-48769330-48770299, MOR264-10P
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258110
Or14c42-ps1
Name: olfactory receptor family 14 subfamily C member 42, pseudogene 1
Synonyms: GA_x6K02T2NHDJ-9553029-9552092, Olfr296-ps1, MOR220-5_p
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404375
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to C, chromosome 1 at 36,779,246 bp (GRCm38)
  • G to T, chromosome 1 at 88,701,639 bp (GRCm38)
  • T to C, chromosome 1 at 155,137,684 bp (GRCm38)
  • A to T, chromosome 1 at 181,766,339 bp (GRCm38)
  • C to T, chromosome 2 at 87,284,727 bp (GRCm38)
  • T to C, chromosome 2 at 88,794,919 bp (GRCm38)
  • C to A, chromosome 3 at 32,956,678 bp (GRCm38)
  • A to T, chromosome 3 at 38,456,869 bp (GRCm38)
  • G to T, chromosome 3 at 85,672,225 bp (GRCm38)
  • C to T, chromosome 3 at 90,199,866 bp (GRCm38)
  • A to G, chromosome 4 at 62,312,316 bp (GRCm38)
  • A to G, chromosome 5 at 41,818,364 bp (GRCm38)
  • A to T, chromosome 5 at 64,955,354 bp (GRCm38)
  • G to T, chromosome 5 at 73,118,458 bp (GRCm38)
  • A to G, chromosome 5 at 114,626,826 bp (GRCm38)
  • A to T, chromosome 6 at 40,245,600 bp (GRCm38)
  • T to C, chromosome 6 at 48,975,903 bp (GRCm38)
  • C to T, chromosome 7 at 3,394,486 bp (GRCm38)
  • T to G, chromosome 7 at 14,222,520 bp (GRCm38)
  • T to A, chromosome 7 at 19,065,407 bp (GRCm38)
  • T to C, chromosome 7 at 42,043,793 bp (GRCm38)
  • T to A, chromosome 7 at 86,561,742 bp (GRCm38)
  • T to C, chromosome 7 at 99,336,959 bp (GRCm38)
  • T to A, chromosome 7 at 120,042,173 bp (GRCm38)
  • T to A, chromosome 8 at 70,070,006 bp (GRCm38)
  • C to T, chromosome 8 at 75,117,540 bp (GRCm38)
  • T to A, chromosome 9 at 14,551,685 bp (GRCm38)
  • C to T, chromosome 9 at 45,179,402 bp (GRCm38)
  • T to C, chromosome 9 at 54,589,898 bp (GRCm38)
  • T to C, chromosome 10 at 21,307,705 bp (GRCm38)
  • T to G, chromosome 10 at 52,418,034 bp (GRCm38)
  • T to A, chromosome 10 at 103,022,232 bp (GRCm38)
  • C to T, chromosome 10 at 127,186,086 bp (GRCm38)
  • T to C, chromosome 11 at 32,216,028 bp (GRCm38)
  • T to C, chromosome 11 at 67,197,345 bp (GRCm38)
  • A to G, chromosome 11 at 118,036,330 bp (GRCm38)
  • G to A, chromosome 12 at 51,958,995 bp (GRCm38)
  • C to A, chromosome 12 at 104,781,934 bp (GRCm38)
  • T to C, chromosome 13 at 21,611,745 bp (GRCm38)
  • G to A, chromosome 13 at 98,249,160 bp (GRCm38)
  • T to A, chromosome 14 at 30,942,913 bp (GRCm38)
  • C to A, chromosome 14 at 32,174,508 bp (GRCm38)
  • T to A, chromosome 14 at 34,147,124 bp (GRCm38)
  • T to C, chromosome 15 at 82,064,715 bp (GRCm38)
  • T to A, chromosome 16 at 58,926,389 bp (GRCm38)
  • G to C, chromosome 16 at 87,410,339 bp (GRCm38)
  • G to T, chromosome 17 at 24,317,125 bp (GRCm38)
  • C to T, chromosome 17 at 25,167,710 bp (GRCm38)
  • G to A, chromosome 17 at 34,514,166 bp (GRCm38)
  • C to T, chromosome 17 at 35,425,209 bp (GRCm38)
  • T to A, chromosome 17 at 40,207,760 bp (GRCm38)
  • A to G, chromosome 17 at 67,794,271 bp (GRCm38)
  • A to C, chromosome 18 at 37,012,280 bp (GRCm38)
  • A to G, chromosome 18 at 50,139,466 bp (GRCm38)
  • C to T, chromosome 19 at 25,147,346 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9654 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069447-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.