Strain Name:
C57BL/6J-MtgxR9690Btlr/Mmmh
Stock Number:
069483-MU
Citation ID:
RRID:MMRRC_069483-MU
Other Names:
R9690 (G1)
Major Collection:

Strain Information

Epb41l1
Name: erythrocyte membrane protein band 4.1 like 1
Synonyms: 4.1N, Epb4.1l1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13821
HGNC: HGNC:3378
Homologene: 8126
Atf2
Name: activating transcription factor 2
Synonyms: D130078H02Rik, mXBP, CRE-BP, ATF-2, Creb2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 11909
HGNC: HGNC:784
Homologene: 31061
Spidr
Name: scaffolding protein involved in DNA repair
Synonyms: 2310008H04Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224008
VEGA: 16
Homologene: 51693
Uchl5
Name: ubiquitin carboxyl-terminal esterase L5
Synonyms: 5830413B11Rik, Uch37
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 56207
Homologene: 9326
Apbb2
Name: amyloid beta precursor protein binding family B member 2
Synonyms: Rirl1, 2310007D03Rik, TR2L, Zfra, FE65L1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11787
HGNC: HGNC:582
Homologene: 32079
Gapvd1
Name: GTPase activating protein and VPS9 domains 1
Synonyms: 4432404J10Rik, 2010005B09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66691
Homologene: 32637
Ep300
Name: E1A binding protein p300
Synonyms: KAT3B, p300
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 328572
HGNC: HGNC:3373
Homologene: 1094
Epha8
Name: Eph receptor A8
Synonyms: EphA8, Hek3, Eek
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13842
HGNC: HGNC:3391
Homologene: 22436
Med13
Name: mediator complex subunit 13
Synonyms: 1110067M05Rik, Trap240, Thrap1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327987
Homologene: 21067
Olfm3
Name: olfactomedin 3
Synonyms: optimedin, B230206G02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229759
Homologene: 17103
Rmnd5b
Name: required for meiotic nuclear division 5 homolog B
Synonyms: 0610039K22Rik, Gid2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 66089
Homologene: 100777
Mtcl2
Name: microtubule crosslinking factor 2
Synonyms: 9830001H06Rik, D430036N24Rik, Soga1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 320706
Homologene: 52382
Myh13
Name: myosin, heavy polypeptide 13, skeletal muscle
Synonyms: extraocular myosin, MyHC-eo, EO Myosin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544791
HGNC: HGNC:7571
Homologene: 55780
Nynrin
Name: NYN domain and retroviral integrase containing
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 277154
VEGA: 14
Homologene: 19483
AI182371
Name: expressed sequence AI182371
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98870
Homologene: 87268
Trmt11
Name: tRNA methyltransferase 11
Synonyms: 3110045I18Rik, 2410075D05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 73681
VEGA: 10
Homologene: 6876
Tnxb
Name: tenascin XB
Synonyms: Tnx, TN-MHC
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 81877
Homologene: 49589
Sema4f
Name: sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain
Synonyms: Sema W
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 20355
Homologene: 3147
Letm2
Name: leucine zipper-EF-hand containing transmembrane protein 2
Synonyms: D030041N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270035
Homologene: 56358
Spata16
Name: spermatogenesis associated 16
Synonyms: Nyd-sp12, spermatogenesis-related protein, 4930503K02Rik, 4921511F01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70862
Homologene: 49974
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637908
Homologene: 104040
Fam83b
Name: family with sequence similarity 83, member B
Synonyms: C530008M07Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208994
Homologene: 19478
Proc
Name: protein C
Synonyms: PC, inactivator of coagulation factors Va, VIII
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 19123
VEGA: 18
HGNC: HGNC:9451
Homologene: 37288
Or4k35
Name: olfactory receptor family 4 subfamily K member 35
Synonyms: Olfr1277, MOR248-11, GA_x6K02T2Q125-72321818-72320907
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258391
Homologene: 105176
Or1j11
Name: olfactory receptor family 1 subfamily E member 1
Synonyms: Olfr339, MOR136-3, GA_x6K02T2NLDC-33116096-33117025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258951
Homologene: 133615
Sipa1l2
Name: signal-induced proliferation-associated 1 like 2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244668
Homologene: 18956
Vmn1r87
Name: vomeronasal 1 receptor 87
Synonyms: V1rk1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 171261
Homologene: 134023
Ddx59
Name: DEAD box helicase 59
Synonyms: 4833411G06Rik, 1210002B07Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67997
Homologene: 12222
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Itih3
Name: inter-alpha trypsin inhibitor, heavy chain 3
Synonyms: Itih-3, Intin3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16426
HGNC: HGNC:6168
Homologene: 1669
Cnnm1
Name: cyclin M1
Synonyms: Acdp1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 83674
VEGA: 19
HGNC: HGNC:102
Homologene: 10673
Tspyl5
Name: testis-specific protein, Y-encoded-like 5
Synonyms: E130308C19Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239364
VEGA: 15
Homologene: 14134
Kcnip4
Name: Kv channel interacting protein 4
Synonyms: KChIP4a, Calp250
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 80334
Homologene: 23528
Cyp4f17
Name: cytochrome P450, family 4, subfamily f, polypeptide 17
Synonyms: EG208285
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 208285
VEGA: 17
Homologene: 129713
Cage1
Name: cancer antigen 1
Synonyms: Ctag3, 4933427I01Rik, CAGE1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71213
Homologene: 18484
Ccdc121rt3
Name: coiled-coil domain containing 121, retrogene 3
Synonyms: Gm6583
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 625424
Homologene: 116059
Or8b3b
Name: olfactory receptor family 8 subfamily B member 3B
Synonyms: Olfr918, MOR164-3, GA_x6K02T2PVTD-32375756-32374818
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258372
VEGA: 9
Or5w22
Name: olfactory receptor family 5 subfamily W member 22
Synonyms: MOR177-5, Olfr4-2, Olfr153, V5, GA_x6K02T2Q125-49033418-49034341
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 110511
Homologene: 128127
Pals1
Name: protein associated with LIN7 1, MAGUK family member
Synonyms: Pals1, 3830420B02Rik, Mpp5
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56217
VEGA: 12
Homologene: 9512
Ptpn20
Name: protein tyrosine phosphatase, non-receptor type 20
Synonyms: typ
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 19256
VEGA: 14
Homologene: 74905
Irgq
Name: immunity-related GTPase family, Q
Synonyms: FKSG27
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 210146
Homologene: 17696
Mak16
Name: MAK16 homolog
Synonyms: Rbm13, 2600016B03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67920
Homologene: 5296
Gm5798
Name: predicted gene 5798
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 108168148
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to A, chromosome 1 at 136,424,802 bp (GRCm38)
  • T to C, chromosome 1 at 143,794,278 bp (GRCm38)
  • C to T, chromosome 2 at 34,728,480 bp (GRCm38)
  • T to A, chromosome 2 at 35,100,588 bp (GRCm38)
  • T to A, chromosome 2 at 36,421,518 bp (GRCm38)
  • A to T, chromosome 2 at 73,845,469 bp (GRCm38)
  • C to A, chromosome 2 at 87,532,415 bp (GRCm38)
  • C to T, chromosome 2 at 111,269,477 bp (GRCm38)
  • A to T, chromosome 2 at 156,514,118 bp (GRCm38)
  • A to T, chromosome 2 at 157,020,214 bp (GRCm38)
  • A to T, chromosome 3 at 26,913,283 bp (GRCm38)
  • A to T, chromosome 3 at 115,096,944 bp (GRCm38)
  • A to T, chromosome 3 at 115,096,945 bp (GRCm38)
  • G to T, chromosome 4 at 136,938,586 bp (GRCm38)
  • T to A, chromosome 5 at 48,398,504 bp (GRCm38)
  • C to T, chromosome 5 at 66,452,178 bp (GRCm38)
  • T to C, chromosome 5 at 112,355,434 bp (GRCm38)
  • A to T, chromosome 6 at 82,935,671 bp (GRCm38)
  • A to G, chromosome 7 at 12,581,985 bp (GRCm38)
  • A to G, chromosome 7 at 13,132,336 bp (GRCm38)
  • G to T, chromosome 7 at 24,534,155 bp (GRCm38)
  • T to A, chromosome 8 at 25,587,419 bp (GRCm38)
  • T to C, chromosome 8 at 31,160,770 bp (GRCm38)
  • T to C, chromosome 8 at 125,492,257 bp (GRCm38)
  • C to A, chromosome 9 at 38,673,181 bp (GRCm38)
  • A to G, chromosome 9 at 76,491,220 bp (GRCm38)
  • A to C, chromosome 10 at 30,560,942 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • T to C, chromosome 11 at 51,627,684 bp (GRCm38)
  • C to T, chromosome 11 at 67,358,368 bp (GRCm38)
  • A to T, chromosome 11 at 86,278,844 bp (GRCm38)
  • T to A, chromosome 12 at 78,819,343 bp (GRCm38)
  • A to G, chromosome 13 at 38,019,165 bp (GRCm38)
  • T to C, chromosome 14 at 30,918,307 bp (GRCm38)
  • T to C, chromosome 14 at 33,631,219 bp (GRCm38)
  • T to G, chromosome 14 at 41,348,639 bp (GRCm38)
  • T to C, chromosome 14 at 55,870,747 bp (GRCm38)
  • C to A, chromosome 15 at 33,687,287 bp (GRCm38)
  • A to C, chromosome 15 at 81,636,195 bp (GRCm38)
  • T to C, chromosome 16 at 16,140,785 bp (GRCm38)
  • T to A, chromosome 17 at 32,506,976 bp (GRCm38)
  • T to C, chromosome 17 at 34,717,197 bp (GRCm38)
  • C to T, chromosome 18 at 32,123,318 bp (GRCm38)
  • A to G, chromosome 19 at 43,471,906 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9690 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069483-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.