Strain Name:
C57BL/6J-MtgxR9742Btlr/Mmmh
Stock Number:
069988-MU
Citation ID:
RRID:MMRRC_069988-MU
Other Names:
R9742 (G1)
Major Collection:

Strain Information

Ldb1
Name: LIM domain binding 1
Synonyms: CLIM2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 16825
HGNC: HGNC:6532
Homologene: 2891
Dtnb
Name: dystrobrevin, beta
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 13528
HGNC: HGNC:3058
Homologene: 74875
Ak2
Name: adenylate kinase 2
Synonyms: Ak-2, D4Ertd220e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11637
HGNC: HGNC:362
Homologene: 1227
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99633
Homologene: 22712
Fndc3a
Name: fibronectin type III domain containing 3A
Synonyms: 1700094E19Rik, F730017H24Rik, Fndc3, D14Ertd453e, sys
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 319448
Homologene: 8952
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Brat1
Name: BRCA1-associated ATM activator 1
Synonyms: Baat1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231841
Homologene: 16776
Nmnat1
Name: nicotinamide nucleotide adenylyltransferase 1
Synonyms: D4Cole1e, 5730441G13Rik, 2610529L11Rik, nmnat, nicotinamide mononucleotide adenylyl transferase
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 66454
Homologene: 39074
Mrtfa
Name: myocardin related transcription factor A
Synonyms: Mkl1, Bsac, Mal, MRTF-A
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223701
Homologene: 32487
Epg5
Name: ectopic P-granules 5 autophagy tethering factor
Synonyms: 5430411K18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 100502841
VEGA: 18
Homologene: 14575
Acsf2
Name: acyl-CoA synthetase family member 2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 264895
Homologene: 23519
Epha6
Name: Eph receptor A6
Synonyms: m-ehk2, Hek12, Ehk2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 13840
Homologene: 56396
Lsr
Name: lipolysis stimulated lipoprotein receptor
Synonyms: ILDR3, Lisch7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 54135
Homologene: 9306
Strbp
Name: spermatid perinuclear RNA binding protein
Synonyms: 6430510M02Rik, Spnr, C230082I21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20744
Homologene: 7548
Smarcc2
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Synonyms: 5930405J04Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 68094
VEGA: 10
Homologene: 2312
Fbxo33
Name: F-box protein 33
Synonyms: 5730501N20Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 70611
Homologene: 16501
Myh6
Name: myosin, heavy polypeptide 6, cardiac muscle, alpha
Synonyms: Myhc-a, alpha cardiac MHC, Myhca, alphaMHC, alpha myosin, A830009F23Rik, cardiomyopathy, hypertrophic 1, alpha-MHC
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 17888
HGNC: HGNC:7576
Homologene: 124414
Cmya5
Name: cardiomyopathy associated 5
Synonyms: 2310076E21Rik, Myospryn, 2310076E16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 76469
VEGA: 13
Homologene: 137367
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208169
Homologene: 19505
Trpm6
Name: transient receptor potential cation channel, subfamily M, member 6
Synonyms: CHAK2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 225997
VEGA: 19
Homologene: 9767
Zhx2
Name: zinc fingers and homeoboxes 2
Synonyms: Raf, Afr-1, Afr1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 387609
Homologene: 8968
Wdfy4
Name: WD repeat and FYVE domain containing 4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 545030
Homologene: 83473
Actrt3
Name: actin related protein T3
Synonyms: 1700119I24Rik, Arpm1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76652
Homologene: 13038
Dusp26
Name: dual specificity phosphatase 26
Synonyms: 2310043K02Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66959
Homologene: 11421
Il17ra
Name: interleukin 17 receptor A
Synonyms: Il17r, VDw217
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 16172
HGNC: HGNC:5985
Homologene: 7378
Unc5d
Name: unc-5 netrin receptor D
Synonyms: D930029E11Rik, Unc5h4
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 210801
Homologene: 15450
Cfap65
Name: cilia and flagella associated protein 65
Synonyms: B230363K08Rik, Ccdc108
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241116
Homologene: 28093
Trim40
Name: tripartite motif-containing 40
Synonyms: LOC240093, LOC333872, LOC195359
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 195359
Homologene: 34709
Plch2
Name: phospholipase C, eta 2
Synonyms: A930027K05Rik, PLCeta2, Plcl4
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 269615
Homologene: 85172
Or10ag53
Name: olfactory receptor family 10 subfamily AG member 53
Synonyms: GA_x6K02T2Q125-48736906-48737886, MOR273-4P, Olfr1530-ps1, Olfr1115, MOR273-4P, MOR264-20
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258294
Homologene: 27114
Muc17
Name: mucin 17, cell surface associated
Synonyms: Muc3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 666339
Homologene: 141159
Slc22a19
Name: solute carrier family 22 (organic anion transporter), member 19
Synonyms: Oat5, D630043A20Rik, Slc22a9
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 207151
Homologene: 133125
Acan
Name: aggrecan
Synonyms: b2b183Clo, Agc1, Cspg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11595
HGNC: HGNC:319
Homologene: 137204
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Vmn2r118
Name: vomeronasal 2, receptor 118
Synonyms: EG383258, Vmn2r119, EG668547
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 383258
Homologene: 129687
Xrra1
Name: X-ray radiation resistance associated 1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 446101
Homologene: 19547
Lrrc27
Name: leucine rich repeat containing 27
Synonyms: 2310044E02Rik, 1700071K18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 76612
Homologene: 19268
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: PI3K-C2beta, C330011J12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Mtcl3
Name: MTCL family member 3
Synonyms: 6330407J23Rik, Soga3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 67412
VEGA: 10
Homologene: 28227
Atp4b
Name: ATPase, H+/K+ exchanging, beta polypeptide
Synonyms: H,K-ATPase-Beta, H+,K+-ATPase, H+/K+-ATPase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11945
HGNC: HGNC:820
Homologene: 20182
Mpi
Name: mannose phosphate isomerase
Synonyms: 1110002E17Rik, Mpi-1, Mpi1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110119
HGNC: HGNC:7216
Homologene: 1825
Khdc1c
Name: KH domain containing 1C
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 433278
Homologene: 134524
Or5b108
Name: olfactory receptor family 5 subfamily B member 108
Synonyms: MOR202-13, GA_x6K02T2RE5P-3517488-3518411, Olfr1462
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258688
HGNC: HGNC:8324
Homologene: 133607
Fam89b
Name: family with sequence similarity 89, member B
Synonyms: Mtvr2, Fam89b, 1110021A21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 17826
Homologene: 18749
Cuedc2
Name: CUE domain containing 2
Synonyms: 3010002G01Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 67116
VEGA: 19
Homologene: 11430
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • T to G, chromosome 1 at 21,369,721 bp (GRCm38)
  • T to C, chromosome 1 at 74,904,681 bp (GRCm38)
  • A to G, chromosome 1 at 133,094,749 bp (GRCm38)
  • T to C, chromosome 2 at 37,625,256 bp (GRCm38)
  • T to C, chromosome 2 at 87,252,032 bp (GRCm38)
  • T to C, chromosome 3 at 30,598,285 bp (GRCm38)
  • A to G, chromosome 3 at 148,836,350 bp (GRCm38)
  • T to A, chromosome 4 at 129,008,168 bp (GRCm38)
  • T to A, chromosome 4 at 149,468,881 bp (GRCm38)
  • C to T, chromosome 4 at 154,998,455 bp (GRCm38)
  • A to G, chromosome 5 at 137,138,279 bp (GRCm38)
  • A to G, chromosome 5 at 140,718,157 bp (GRCm38)
  • T to A, chromosome 6 at 120,481,505 bp (GRCm38)
  • CTCTTCTTCTTCTTCTTC to CTCTTCTTCTTCTTC, chromosome 7 at 30,958,067 bp (GRCm38)
  • T to G, chromosome 7 at 79,099,367 bp (GRCm38)
  • A to G, chromosome 7 at 99,914,453 bp (GRCm38)
  • C to T, chromosome 7 at 139,226,313 bp (GRCm38)
  • G to A, chromosome 8 at 13,390,097 bp (GRCm38)
  • A to G, chromosome 8 at 28,666,764 bp (GRCm38)
  • A to T, chromosome 8 at 31,094,170 bp (GRCm38)
  • A to G, chromosome 9 at 57,545,323 bp (GRCm38)
  • C to A, chromosome 10 at 29,148,398 bp (GRCm38)
  • G to A, chromosome 10 at 120,038,664 bp (GRCm38)
  • A to G, chromosome 10 at 128,461,353 bp (GRCm38)
  • G to A, chromosome 11 at 72,858,353 bp (GRCm38)
  • C to A, chromosome 11 at 94,573,137 bp (GRCm38)
  • A to T, chromosome 12 at 3,686,740 bp (GRCm38)
  • A to G, chromosome 12 at 59,204,896 bp (GRCm38)
  • T to C, chromosome 13 at 93,095,427 bp (GRCm38)
  • G to A, chromosome 14 at 33,088,030 bp (GRCm38)
  • T to A, chromosome 14 at 54,956,599 bp (GRCm38)
  • C to A, chromosome 14 at 72,540,253 bp (GRCm38)
  • A to G, chromosome 15 at 57,823,410 bp (GRCm38)
  • G to A, chromosome 15 at 81,016,979 bp (GRCm38)
  • T to A, chromosome 16 at 45,580,253 bp (GRCm38)
  • T to C, chromosome 16 at 60,205,702 bp (GRCm38)
  • A to G, chromosome 17 at 36,889,010 bp (GRCm38)
  • T to C, chromosome 17 at 55,611,009 bp (GRCm38)
  • T to A, chromosome 18 at 77,980,955 bp (GRCm38)
  • A to T, chromosome 19 at 5,729,302 bp (GRCm38)
  • T to C, chromosome 19 at 7,710,916 bp (GRCm38)
  • T to C, chromosome 19 at 13,191,405 bp (GRCm38)
  • G to T, chromosome 19 at 18,823,402 bp (GRCm38)
  • A to G, chromosome 19 at 46,035,419 bp (GRCm38)
  • A to G, chromosome 19 at 46,331,288 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9742 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069988-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.