Strain Name:
C57BL/6J-MtgxR9752Btlr/Mmmh
Stock Number:
069998-MU
Citation ID:
RRID:MMRRC_069998-MU
Other Names:
R9752 (G1)
Major Collection:

Strain Information

Nrp2
Name: neuropilin 2
Synonyms: NP2, Npn-2, Npn2, NP-2, 1110048P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18187
HGNC: HGNC:8005
Homologene: 2875
Gatad2a
Name: GATA zinc finger domain containing 2A
Synonyms: 1110066C11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234366
Homologene: 9766
Mast2
Name: microtubule associated serine/threonine kinase 2
Synonyms: MAST205, Mtssk
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17776
Homologene: 7428
Usp48
Name: ubiquitin specific peptidase 48
Synonyms: D330022K21Rik, 2810449C13Rik, Usp31
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 170707
Homologene: 12988
Diaph1
Name: diaphanous related formin 1
Synonyms: p140mDia, Drf1, Dia1, D18Wsu154e, mDia1, Diap1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13367
HGNC: HGNC:2876
Homologene: 129567
Lrch4
Name: leucine-rich repeats and calponin homology (CH) domain containing 4
Synonyms: 2900069C24Rik, LRRN4, LRN, 2810008P14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231798
HGNC: HGNC:6691
Homologene: 20532
Resf1
Name: retroelement silencing factor 1
Synonyms: GET, 2810474O19Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 67246
Homologene: 19251
Kif15
Name: kinesin family member 15
Synonyms: N-10 kinesin, HKLP2, 3930402I10Rik, 3110023M17Rik, Knsl7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 209737
VEGA: 9
Homologene: 23210
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Usp34
Name: ubiquitin specific peptidase 34
Synonyms: A530081C03Rik, Murr2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 17847
Homologene: 40978
Prr11
Name: proline rich 11
Synonyms: B930067F20Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 270906
Homologene: 10123
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233824
Homologene: 33431
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Tlr4
Name: toll-like receptor 4
Synonyms: Lps, Rasl2-8, lipopolysaccharide response
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21898
Homologene: 41317
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 404710
Homologene: 26400
Msh6
Name: mutS homolog 6
Synonyms: Msh6, GTBP, Gtmbp
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17688
VEGA: 17
HGNC: HGNC:7329
Homologene: 149
Ppp4r3a
Name: protein phosphatase 4 regulatory subunit 3A
Synonyms: 1110034C04Rik, Smek1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 68734
VEGA: 12
Homologene: 69510
Ntn1
Name: netrin 1
Synonyms: Netrin-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18208
HGNC: HGNC:8029
Homologene: 21008
Med13
Name: mediator complex subunit 13
Synonyms: Trap240, 1110067M05Rik, Thrap1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327987
Homologene: 21067
Zfp335
Name: zinc finger protein 335
Synonyms: 1810045J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329559
Homologene: 11129
Rrn3
Name: RRN3 RNA polymerase I transcription factor homolog (yeast)
Synonyms: E130302O19Rik, TIF-1A
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106298
VEGA: 16
Homologene: 39531
Entr1
Name: endosome associated trafficking regulator 1
Synonyms: C630038K21Rik, C330016H24Rik, Sdccag3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68112
Homologene: 74578
Micu3
Name: mitochondrial calcium uptake family, member 3
Synonyms: 2900075B16Rik, Efha2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 78506
Homologene: 15058
Clhc1
Name: clathrin heavy chain linker domain containing 1
Synonyms: 1700034F02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 73324
Homologene: 17569
Gna14
Name: guanine nucleotide binding protein, alpha 14
Synonyms: G alpha 14
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14675
VEGA: 19
HGNC: HGNC:4382
Homologene: 68386
Ighmbp2
Name: immunoglobulin mu DNA binding protein 2
Synonyms: Catf1, AEP, Smbp2, sma, Smubp2, p110 subunit, RIPE3b1, Smbp-2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20589
HGNC: HGNC:5542
Homologene: 1642
Zrsr2
Name: zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2
Synonyms: 35kDa, 5031411E02Rik, A230052C13Rik, U2af1-rs2
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 22184
Homologene: 21061
Haus8
Name: 4HAUS augmin-like complex, subunit 8
Synonyms: 2410004L22Rik, Hice1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76478
Homologene: 12644
Zfp266
Name: zinc finger protein 266
Synonyms: 5330440G10Rik, 5730601F06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 77519
Homologene: 105676
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Trpc6
Name: transient receptor potential cation channel, subfamily C, member 6
Synonyms: mtrp6, Trrp6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22068
VEGA: 9
Homologene: 37944
Slc7a8
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Synonyms: LAT2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50934
VEGA: 14
Homologene: 8166
Kcp
Name: kielin/chordin-like protein
Synonyms: LOC333088, KCP, Crim2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 333088
Homologene: 87817
Or52h9
Name: olfactory receptor family 52 subfamily H member 9
Synonyms: GA_x6K02T2PBJ9-7179540-7180481, MOR31-11, Olfr651
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258809
Homologene: 64922
Hsf5
Name: heat shock transcription factor family member 5
Synonyms: LOC327992
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327992
Homologene: 52701
Slc26a2
Name: solute carrier family 26 (sulfate transporter), member 2
Synonyms: ST-OB, Dtd
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13521
Homologene: 73876
Or2t26
Name: olfactory receptor family 2 subfamily T member 26
Synonyms: GA_x6K02T2QP88-6286247-6285294, MOR277-1, Olfr1395
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258877
Homologene: 105890
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235505
Homologene: 25183
Flg2
Name: filaggrin family member 2
Synonyms: EG229574
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229574
Homologene: 134146
Itgav
Name: integrin alpha V
Synonyms: vitronectin receptor alpha polypeptide (VNRA), CD51, alphav-integrin, 1110004F14Rik, 2610028E01Rik, D430040G12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16410
HGNC: HGNC:6150
Homologene: 20510
Lipo2
Name: lipase, member O2
Synonyms: Gm8981
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 101055671
Homologene: 103863
Gtf3c4
Name: general transcription factor IIIC, polypeptide 4
Synonyms: KAT12
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269252
HGNC: HGNC:4667
Homologene: 8147
Nxnl2
Name: nucleoredoxin-like 2
Synonyms: 4930519N16Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75124
VEGA: 13
Homologene: 115787
Styk1
Name: serine/threonine/tyrosine kinase 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243659
Homologene: 49545
Clip1
Name: CAP-GLY domain containing linker protein 1
Synonyms: cytoplasmic linker protein 50, Clip50, CLIP-170, 1110007I12Rik, 4631429H07Rik, Rsn, Clip 170, restin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56430
Homologene: 74455
Ano2
Name: anoctamin 2
Synonyms: Tmem16b
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243634
HGNC: HGNC:1183
Homologene: 23221
Nphp4
Name: nephronophthisis 4 (juvenile) homolog (human)
Synonyms: 4930564O18Rik, nmf192
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 260305
Homologene: 9024
Gbp2b
Name: guanylate binding protein 2b
Synonyms: Mag-1, Mpa-1, Gbp-1, Mpa1, LIMIT, Gbp1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 14468
Homologene: 137233
Cr2
Name: complement receptor 2
Synonyms: CD21, CD35, Cr-1, Cr-2, Cr1, C3DR
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12902
HGNC: HGNC:2336
Homologene: 55611
Or7e176
Name: olfactory receptor family 7 subfamily E member 176
Synonyms: GA_x6K02T2PVTD-13999915-14000844, MOR145-3, Olfr872
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258553
HGNC: HGNC:8396
Homologene: 138312
Fstl1
Name: follistatin-like 1
Synonyms: TSC-36
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14314
HGNC: HGNC:3972
Homologene: 5144
Or52r1c
Name: olfactory receptor family 52 subfamily R member 1C
Synonyms: GA_x6K02T2PBJ9-5796876-5797820, MOR30-2, Olfr584
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259056
Scd4
Name: stearoyl-coenzyme A desaturase 4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 329065
Homologene: 77322
Zfp677
Name: zinc finger protein 677
Synonyms: A830058L05Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 210503
Homologene: 138402
Or6c219
Name: olfactory receptor family 6 subfamily C member 219
Synonyms: GA_x6K02T2PULF-11624146-11623190, MOR110-2, Olfr818
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 258773
Homologene: 74100
Mrps10
Name: mitochondrial ribosomal protein S10
Synonyms: Rpms10, 1110038B19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 64657
Homologene: 10028
Ifi209
Name: interferon activated gene 209
Synonyms: Ifix, Pyhin1, Pyhin-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 236312
HGNC: HGNC:5395
Homologene: 115929
Or1e16
Name: olfactory receptor family 1 subfamily E member 16
Synonyms: MOR135-13, GA_x6K02T2P1NL-3556334-3555390, I54, Olfr1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258923
Homologene: 115482
Ppp1r42
Name: protein phosphatase 1, regulatory subunit 42
Synonyms: 1700011J18Rik, 4930418G15Rik, Lrrc67
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69312
Homologene: 27077
Wfikkn2
Name: WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
Synonyms: Gasp1, 2610304F08Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 278507
Homologene: 35284
Spi1
Name: Spi-1 proto-oncogene
Synonyms: Spi-1, Sfpi-1, Tfpu.1, PU.1, Dis-1, Tcfpu1, Sfpi1, spleen focus forming virus (SFFV) proviral integration oncogene
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20375
Homologene: 2346
Vkorc1l1
Name: vitamin K epoxide reductase complex, subunit 1-like 1
Synonyms: 2310024K08Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69568
Homologene: 18308
Cc2d2b
Name: coiled-coil and C2 domain containing 2B
Synonyms: EG668310
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 668310
Homologene: 141114
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to G, chromosome 1 at 10,003,449 bp (GRCm38)
  • A to T, chromosome 1 at 62,812,567 bp (GRCm38)
  • A to T, chromosome 1 at 173,644,669 bp (GRCm38)
  • T to C, chromosome 1 at 195,141,267 bp (GRCm38)
  • T to C, chromosome 2 at 26,386,978 bp (GRCm38)
  • C to A, chromosome 2 at 28,834,114 bp (GRCm38)
  • T to A, chromosome 2 at 83,770,107 bp (GRCm38)
  • A to G, chromosome 2 at 91,113,321 bp (GRCm38)
  • C to T, chromosome 2 at 164,907,427 bp (GRCm38)
  • C to A, chromosome 3 at 88,108,869 bp (GRCm38)
  • A to T, chromosome 3 at 93,201,160 bp (GRCm38)
  • A to T, chromosome 3 at 142,608,156 bp (GRCm38)
  • A to G, chromosome 4 at 66,839,675 bp (GRCm38)
  • G to T, chromosome 4 at 116,322,311 bp (GRCm38)
  • G to A, chromosome 4 at 137,613,826 bp (GRCm38)
  • A to G, chromosome 4 at 152,537,280 bp (GRCm38)
  • A to T, chromosome 5 at 121,310,681 bp (GRCm38)
  • C to T, chromosome 5 at 121,334,352 bp (GRCm38)
  • T to C, chromosome 5 at 123,621,946 bp (GRCm38)
  • T to A, chromosome 5 at 129,982,237 bp (GRCm38)
  • T to A, chromosome 5 at 137,637,956 bp (GRCm38)
  • A to T, chromosome 6 at 29,497,755 bp (GRCm38)
  • C to T, chromosome 6 at 125,863,536 bp (GRCm38)
  • CTCTTCATGATTTTCTT to CTCTT, chromosome 6 at 131,301,649 bp (GRCm38)
  • T to A, chromosome 6 at 149,326,570 bp (GRCm38)
  • A to G, chromosome 7 at 25,271,978 bp (GRCm38)
  • T to A, chromosome 7 at 103,086,462 bp (GRCm38)
  • A to T, chromosome 7 at 104,553,323 bp (GRCm38)
  • C to A, chromosome 7 at 121,981,416 bp (GRCm38)
  • A to G, chromosome 8 at 40,380,710 bp (GRCm38)
  • A to G, chromosome 8 at 69,912,189 bp (GRCm38)
  • A to C, chromosome 8 at 71,263,087 bp (GRCm38)
  • A to G, chromosome 8 at 95,761,391 bp (GRCm38)
  • C to A, chromosome 9 at 8,643,640 bp (GRCm38)
  • G to A, chromosome 9 at 20,259,908 bp (GRCm38)
  • T to A, chromosome 9 at 20,500,200 bp (GRCm38)
  • A to G, chromosome 9 at 78,707,552 bp (GRCm38)
  • T to C, chromosome 9 at 122,995,825 bp (GRCm38)
  • A to G, chromosome 10 at 120,035,351 bp (GRCm38)
  • T to C, chromosome 10 at 129,945,121 bp (GRCm38)
  • C to T, chromosome 11 at 23,459,182 bp (GRCm38)
  • C to T, chromosome 11 at 29,557,778 bp (GRCm38)
  • T to C, chromosome 11 at 49,148,854 bp (GRCm38)
  • C to T, chromosome 11 at 68,385,886 bp (GRCm38)
  • T to A, chromosome 11 at 73,395,653 bp (GRCm38)
  • A to G, chromosome 11 at 86,283,321 bp (GRCm38)
  • T to C, chromosome 11 at 87,103,590 bp (GRCm38)
  • C to T, chromosome 11 at 87,622,883 bp (GRCm38)
  • T to C, chromosome 11 at 94,238,385 bp (GRCm38)
  • A to T, chromosome 12 at 101,042,504 bp (GRCm38)
  • A to G, chromosome 13 at 51,171,471 bp (GRCm38)
  • T to C, chromosome 14 at 54,758,474 bp (GRCm38)
  • A to G, chromosome 16 at 13,813,231 bp (GRCm38)
  • T to G, chromosome 16 at 37,829,172 bp (GRCm38)
  • T to A, chromosome 17 at 21,398,249 bp (GRCm38)
  • T to C, chromosome 17 at 47,372,647 bp (GRCm38)
  • T to C, chromosome 17 at 87,986,535 bp (GRCm38)
  • T to C, chromosome 18 at 37,903,071 bp (GRCm38)
  • T to A, chromosome 18 at 61,201,938 bp (GRCm38)
  • A to G, chromosome 19 at 3,274,360 bp (GRCm38)
  • G to A, chromosome 19 at 16,609,417 bp (GRCm38)
  • C to G, chromosome 19 at 33,745,821 bp (GRCm38)
  • T to C, chromosome 19 at 40,792,827 bp (GRCm38)
  • T to C, chromosome 19 at 44,334,036 bp (GRCm38)
  • GCTCCTCCTCCTCCTCCT to GCTCCTCCTCCTCCT, chromosome X at 163,936,754 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9752 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
069998-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.