Strain Name:
C57BL/6J-MtgxR9760Btlr/Mmmh
Stock Number:
070005-MU
Citation ID:
RRID:MMRRC_070005-MU
Other Names:
R9760 (G1)
Major Collection:

Strain Information

Ins2
Name: insulin II
Synonyms: Mody4, Ins-2, Mody, InsII
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16334
HGNC: HGNC:6081
Homologene: 173
Grin3a
Name: glutamate receptor ionotropic, NMDA3A
Synonyms: NR3A, NMDAR-L, A830097C19Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242443
Homologene: 128613
Galnt10
Name: polypeptide N-acetylgalactosaminyltransferase 10
Synonyms: C330012K04Rik, GalNAc-T10, Galnt9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 171212
Homologene: 14924
Cfdp1
Name: craniofacial development protein 1
Synonyms: Bucentaur, Bcnt, cp27
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23837
HGNC: HGNC:1873
Homologene: 4611
Nub1
Name: negative regulator of ubiquitin-like proteins 1
Synonyms: NY-REN-18, BS4, 4931404D21Rik, 6330412F12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 53312
Homologene: 41108
Prkdc
Name: protein kinase, DNA activated, catalytic polypeptide
Synonyms: slip, DNAPDcs, DNA-PKcs, DNA-PK, DOXNPH, XRCC7, dxnph
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19090
HGNC: HGNC:9413
Homologene: 5037
Arhgef12
Name: Rho guanine nucleotide exchange factor 12
Synonyms: 2310014B11Rik, LARG
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69632
VEGA: 9
Homologene: 9088
Lcmt1
Name: leucine carboxyl methyltransferase 1
Synonyms: LCMT-1, Lcmt
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 30949
Homologene: 41123
Esrrg
Name: estrogen-related receptor gamma
Synonyms: ERR3, NR3B3, Errg, estrogen-related receptor 3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26381
HGNC: HGNC:3474
Homologene: 55581
Dcaf1
Name: DDB1 and CUL4 associated factor 1
Synonyms: Vprbp, B930007L02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 321006
Homologene: 8805
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Ddx54
Name: DEAD box helicase 54
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 54, APR-5, 2410015A15Rik, DP97
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 71990
Homologene: 5590
Tango6
Name: transport and golgi organization 6
Synonyms: Tmco7, Tango6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 272538
Homologene: 52121
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F37S1, D7H15F32S1, rjs, jdf2, D15F32S1h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
R3hdm2
Name: R3H domain containing 2
Synonyms: 1300003K24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71750
Homologene: 8954
Prpf8
Name: pre-mRNA processing factor 8
Synonyms: DBF3/PRP8, Prp8, D11Bwg0410e, Sfprp8l
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192159
Homologene: 4706
Gbf1
Name: golgi-specific brefeldin A-resistance factor 1
Synonyms: 1700083E03Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 107338
HGNC: HGNC:4181
Homologene: 37897
Ipo13
Name: importin 13
Synonyms: Imp13, Kap13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230673
Homologene: 40968
Malt1
Name: MALT1 paracaspase
Synonyms: paracaspase, D430033E09Rik, Pcasp1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240354
HGNC: HGNC:6819
Homologene: 4938
Dcdc2a
Name: doublecortin domain containing 2a
Synonyms: RU2, Dcdc2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 195208
Homologene: 9483
Ddi2
Name: DNA-damage inducible protein 2
Synonyms: 9130022E05Rik, 1110056G13Rik, 1700027M01Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68817
Homologene: 121661
Fmnl2
Name: formin-like 2
Synonyms: 5430425K04Rik, man
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71409
Homologene: 70871
Rab35
Name: RAB35, member RAS oncogene family
Synonyms: 9530019H02Rik, RAB1C, H-ray
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77407
HGNC: HGNC:9774
Homologene: 21361
Sec63
Name: SEC63 homolog, protein translocation regulator
Synonyms: 5730478J10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 140740
Homologene: 5220
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Wdr89
Name: WD repeat domain 89
Synonyms: 2600001A11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 72338
Homologene: 43791
Dennd5b
Name: DENN domain containing 5B
Synonyms: 9330160C06Rik, D030011O10Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320560
Homologene: 44911
Adamts4
Name: ADAM metallopeptidase with thrombospondin type 1 motif 4
Synonyms: aggrecanase-1, ADAM-TS4
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240913
HGNC: HGNC:220
Homologene: 36169
Pkdrej
Name: polycystin (PKD) family receptor for egg jelly
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18766
VEGA: 15
HGNC: HGNC:9015
Homologene: 4427
Slc38a4
Name: solute carrier family 38, member 4
Synonyms: SNAT4, Ata3, 1700012A18Rik, 1110012E16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69354
VEGA: 15
Homologene: 75077
Vinac1
Name: vinculin/alpha-catenin family member 1
Synonyms: Gm14025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 668894
Homologene: 86340
Col6a6
Name: collagen, type VI, alpha 6
Synonyms: E330026B02Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245026
Homologene: 18260
Fhip2b
Name: FHF complex subunit HOOK interacting protein 2B
Synonyms: G430067P06Rik, Rai16, Fam160b2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 239170
VEGA: 14
Homologene: 23379
Stk35
Name: serine/threonine kinase 35
Synonyms: CLP-36 interacting kinase, 1700054C12Rik, CLIK1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 67333
Homologene: 15441
Cgnl1
Name: cingulin-like 1
Synonyms: Jacop, 9930020M10Rik, 4933421H10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68178
Homologene: 41901
Hycc1
Name: hyccin PI4KA lipid kinase complex subunit 1
Synonyms: hyccin, Fam126a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 84652
Homologene: 57175
Tmem30a
Name: transmembrane protein 30A
Synonyms: D9Wsu20e, 2010200I23Rik, Cdc50a
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 69981
Homologene: 110703
Micall1
Name: microtubule associated monooxygenase, calponin and LIM domain containing -like 1
Synonyms: Mus EST 820961, D15N2e, D15Mit260
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 27008
VEGA: 15
Homologene: 24911
Or10al3
Name: olfactory receptor family 10 subfamily AL member 3
Synonyms: MOR263-7, Olfr119, GA_x6K02T2PSCP-2159633-2160598
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 258095
Homologene: 17195
Gnptab
Name: N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
Synonyms: EG432486
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 432486
Homologene: 32576
Efcab14
Name: EF-hand calcium binding domain 14
Synonyms: 4732418C07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230648
Homologene: 8858
Gbp3
Name: guanylate binding protein 3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 55932
Homologene: 137329
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Tas2r137
Name: taste receptor, type 2, member 137
Synonyms: mt2r41
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 574417
Homologene: 23231
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16565
Homologene: 56868
Clca3b
Name: chloride channel accessory 3B
Synonyms: Clca4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229927
HGNC: HGNC:2017
Homologene: 135610
Zfp229
Name: zinc finger protein 229
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381067
Homologene: 136287
Thoc2l
Name: THO complex subunit 2-like
Synonyms: BC005561, Gm3179
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100042165
Far2
Name: fatty acyl CoA reductase 2
Synonyms: Mlstd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330450
Homologene: 69247
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192950
Homologene: 135717
Gm12185
Name: predicted gene 12185
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 620913
Homologene: 83188
Cep250
Name: centrosomal protein 250
Synonyms: Inmp, Cep2, B230210E21Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16328
HGNC: HGNC:1859
Homologene: 38286
Or5af1
Name: olfactory receptor family 5 subfamily AF member 1
Synonyms: Olfr312, GA_x6K02T2NKPP-575829-574903, MOR222-4P
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258065
Homologene: 77375
Slc23a3
Name: solute carrier family 23 (nucleobase transporters), member 3
Synonyms: SVCT3, Yspl1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22626
Homologene: 65865
Prr27
Name: proline rich 27
Synonyms: 4930432K09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73779
Homologene: 136277
Or8g24
Name: olfactory receptor family 8 subfamily G member 24
Synonyms: MOR171-25, GA_x6K02T2PVTD-32774646-32773699, Olfr938
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258430
VEGA: 9
Ribc2
Name: RIB43A domain with coiled-coils 2
Synonyms: 4930579A10Rik, Trib
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67747
VEGA: 15
Homologene: 9230
Coq4
Name: coenzyme Q4
Synonyms: D2Ertd97e, EST-MNCb4625
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227683
Homologene: 68641
Efhb
Name: EF hand domain family, member B
Synonyms: 4921525D22Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 211482
VEGA: 17
Homologene: 16982
Gm5592
Name: predicted gene 5592
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 434172
Homologene: 45597
Gtf2a1l
Name: general transcription factor IIA, 1-like
Synonyms: Alf, 1700011N16Rik, Gtf2a1lf
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71828
Homologene: 86732
Vmn1r192
Name: vomeronasal 1 receptor 192
Synonyms: V1ri1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 252907
Homologene: 110880
Kcnj15
Name: potassium inwardly-rectifying channel, subfamily J, member 15
Synonyms: Kir4.2, IRKK, 4930414N08Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 16516
HGNC: HGNC:6261
Homologene: 1690
Abat
Name: 4-aminobutyrate aminotransferase
Synonyms: GABA-T, 9630038C02Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 268860
HGNC: HGNC:23
Homologene: 542
Dact3
Name: dishevelled-binding antagonist of beta-catenin 3
Synonyms: EG666671
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 629378
Homologene: 77340
Trav9n-4
Name: T cell receptor alpha variable 9N-4
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 279882
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • ATT to ATTT, chromosome 1 at 75,133,281 bp (GRCm38)
  • G to A, chromosome 1 at 136,148,683 bp (GRCm38)
  • G to A, chromosome 1 at 171,258,765 bp (GRCm38)
  • A to G, chromosome 1 at 188,043,372 bp (GRCm38)
  • G to T, chromosome 2 at 29,788,470 bp (GRCm38)
  • A to G, chromosome 2 at 53,054,515 bp (GRCm38)
  • A to T, chromosome 2 at 129,038,579 bp (GRCm38)
  • G to A, chromosome 2 at 129,800,685 bp (GRCm38)
  • A to G, chromosome 2 at 155,976,553 bp (GRCm38)
  • T to G, chromosome 3 at 142,570,522 bp (GRCm38)
  • T to C, chromosome 3 at 144,846,849 bp (GRCm38)
  • A to T, chromosome 4 at 49,714,213 bp (GRCm38)
  • C to T, chromosome 4 at 115,758,875 bp (GRCm38)
  • T to A, chromosome 4 at 117,905,581 bp (GRCm38)
  • A to G, chromosome 4 at 141,683,885 bp (GRCm38)
  • T to C, chromosome 5 at 23,979,574 bp (GRCm38)
  • T to C, chromosome 5 at 24,692,967 bp (GRCm38)
  • C to A, chromosome 5 at 87,843,135 bp (GRCm38)
  • T to C, chromosome 5 at 104,519,235 bp (GRCm38)
  • C to A, chromosome 5 at 115,640,165 bp (GRCm38)
  • C to T, chromosome 5 at 120,623,607 bp (GRCm38)
  • A to G, chromosome 6 at 40,492,102 bp (GRCm38)
  • C to A, chromosome 6 at 148,158,950 bp (GRCm38)
  • G to A, chromosome 6 at 149,068,499 bp (GRCm38)
  • G to A, chromosome 7 at 16,886,206 bp (GRCm38)
  • A to T, chromosome 7 at 41,289,810 bp (GRCm38)
  • G to C, chromosome 7 at 56,163,911 bp (GRCm38)
  • T to A, chromosome 7 at 123,430,152 bp (GRCm38)
  • A to G, chromosome 7 at 141,807,248 bp (GRCm38)
  • T to A, chromosome 7 at 142,679,448 bp (GRCm38)
  • A to G, chromosome 8 at 106,850,279 bp (GRCm38)
  • T to C, chromosome 8 at 111,768,783 bp (GRCm38)
  • A to T, chromosome 9 at 39,077,975 bp (GRCm38)
  • G to T, chromosome 9 at 42,992,022 bp (GRCm38)
  • G to T, chromosome 9 at 71,645,571 bp (GRCm38)
  • A to T, chromosome 9 at 79,780,592 bp (GRCm38)
  • A to T, chromosome 9 at 105,782,054 bp (GRCm38)
  • A to G, chromosome 9 at 106,874,267 bp (GRCm38)
  • A to G, chromosome 10 at 42,828,948 bp (GRCm38)
  • A to G, chromosome 10 at 88,431,448 bp (GRCm38)
  • G to T, chromosome 10 at 127,444,313 bp (GRCm38)
  • A to G, chromosome 11 at 6,601,662 bp (GRCm38)
  • T to A, chromosome 11 at 48,915,341 bp (GRCm38)
  • G to A, chromosome 11 at 57,765,688 bp (GRCm38)
  • A to G, chromosome 11 at 58,832,026 bp (GRCm38)
  • A to G, chromosome 11 at 75,503,431 bp (GRCm38)
  • A to G, chromosome 12 at 75,633,252 bp (GRCm38)
  • A to G, chromosome 13 at 22,187,840 bp (GRCm38)
  • C to T, chromosome 13 at 25,205,460 bp (GRCm38)
  • T to C, chromosome 14 at 7,929,846 bp (GRCm38)
  • C to A, chromosome 14 at 53,294,833 bp (GRCm38)
  • A to C, chromosome 14 at 70,590,181 bp (GRCm38)
  • G to A, chromosome 15 at 79,120,832 bp (GRCm38)
  • T to A, chromosome 15 at 85,143,367 bp (GRCm38)
  • T to C, chromosome 15 at 85,821,067 bp (GRCm38)
  • T to C, chromosome 15 at 96,998,451 bp (GRCm38)
  • T to C, chromosome 16 at 8,581,930 bp (GRCm38)
  • T to A, chromosome 16 at 15,839,180 bp (GRCm38)
  • T to A, chromosome 16 at 95,295,624 bp (GRCm38)
  • A to T, chromosome 17 at 21,746,294 bp (GRCm38)
  • T to C, chromosome 17 at 37,701,543 bp (GRCm38)
  • A to T, chromosome 17 at 53,463,270 bp (GRCm38)
  • A to G, chromosome 17 at 88,711,592 bp (GRCm38)
  • A to G, chromosome 18 at 65,448,212 bp (GRCm38)
  • C to T, chromosome 19 at 41,130,645 bp (GRCm38)
  • C to A, chromosome 19 at 46,255,698 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9760 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070005-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.