Strain Name:
C57BL/6J-MtgxR9787Btlr/Mmmh
Stock Number:
070032-MU
Citation ID:
RRID:MMRRC_070032-MU
Other Names:
R9787 (G1)
Major Collection:

Strain Information

Dst
Name: dystonin
Synonyms: A830042E19Rik, nmf339, bullous pemphigoid antigen 1, Bpag1, 2310001O04Rik, Bpag, Macf2, BPAG1, BPAG1-n, athetoid, bullous pemphigoid antigen 1, ah, nmf203
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13518
HGNC: HGNC:1090
Homologene: 136716
Nsd1
Name: nuclear receptor-binding SET-domain protein 1
Synonyms: KMT3B
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 18193
VEGA: 13
Homologene: 32543
Dot1l
Name: DOT1 like histone lysine methyltransferase
Synonyms: KMT4, mDot1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 208266
Homologene: 32779
Mtdh
Name: metadherin
Synonyms: 2610103J23Rik, AEG-1, D8Bwg1112e, Lyric, 3D3/Lyric
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67154
Homologene: 12089
Pan2
Name: PAN2 poly(A) specific ribonuclease subunit
Synonyms: Usp52, 1200014O24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103135
VEGA: 10
Homologene: 5918
Fto
Name: FTO alpha-ketoglutarate dependent dioxygenase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 26383
Homologene: 8053
Mbnl1
Name: muscleblind like splicing regulator 1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56758
HGNC: HGNC:6923
Homologene: 23186
Gtf2b
Name: general transcription factor IIB
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229906
HGNC: HGNC:4648
Homologene: 1158
Lpar1
Name: lysophosphatidic acid receptor 1
Synonyms: Gpcr26, Edg2, vzg-1, LPA1, Kdt2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14745
HGNC: HGNC:3166
Homologene: 1072
Il7
Name: interleukin 7
Synonyms: A630026I06Rik, Il-7, hlb368
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 16196
HGNC: HGNC:6023
Homologene: 680
Gsx1
Name: GS homeobox 1
Synonyms: Gsh-1, Gsh1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14842
Homologene: 17092
Pole
Name: polymerase (DNA directed), epsilon
Synonyms: pol-epsilon
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 18973
HGNC: HGNC:9177
Homologene: 4539
Cdin1
Name: CDAN1 interacting nuclease 1
Synonyms: BC052040
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 399568
Homologene: 32780
Tcf7
Name: transcription factor 7, T cell specific
Synonyms: T-cell factor 1, TCF-1, Tcf1, T cell factor-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 21414
Homologene: 137220
Stau2
Name: staufen double-stranded RNA binding protein 2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 29819
Homologene: 8666
Gin1
Name: gypsy retrotransposon integrase 1
Synonyms: 4930429M06, 4930429M06Rik, Zh2c2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 252876
Homologene: 69238
Sugp2
Name: SURP and G patch domain containing 2
Synonyms: Srsf14, Sfrs14
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234373
Homologene: 8923
Optn
Name: optineurin
Synonyms: TFIIIA-INTP, 4930441O07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71648
Homologene: 11085
Zfhx4
Name: zinc finger homeodomain 4
Synonyms: C130041O22Rik, Zfh-4, Zfh4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 80892
Homologene: 23477
Ttn
Name: titin
Synonyms: connectin, shru, D330041I19Rik, 2310057K23Rik, mdm, D830007G01Rik, 2310074I15Rik, 1100001C23Rik, 2310036G12Rik, L56
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Muc6
Name: mucin 6, gastric
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 353328
HGNC: HGNC:7517
Homologene: 18768
Siglecl2
Name: Siglec family like 2
Synonyms: 4931406B18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74054
Homologene: 105741
Cyp2b9
Name: cytochrome P450, family 2, subfamily b, polypeptide 9
Synonyms: Cyp2b, phenobarbitol inducible, type a
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13094
HGNC: HGNC:2615
Homologene: 74933
Unc79
Name: unc-79 homolog
Synonyms: 9030205A07Rik, Mlca3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217843
Homologene: 41397
Umodl1
Name: uromodulin-like 1
Synonyms: D17Ertd488e
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 52020
VEGA: 17
Homologene: 45466
BC034090
Name: cDNA sequence BC034090
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 207792
Homologene: 19490
Zc3hav1l
Name: zinc finger CCCH-type, antiviral 1-like
Synonyms: E430016P22Rik, B130055L09Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209032
Homologene: 15425
Gli3
Name: GLI-Kruppel family member GLI3
Synonyms: Bph, brachyphalangy
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14634
HGNC: HGNC:4319
Homologene: 139
Tcaf3
Name: TRPM8 channel-associated factor 3
Synonyms: Eapa2, Fam115e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 403088
Homologene: 74374
Ctbs
Name: chitobiase
Synonyms: 2210401K11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74245
HGNC: HGNC:2496
Homologene: 3231
Garem2
Name: GRB2 associated regulator of MAPK1 subtype 2
Synonyms: Gareml, LOC242915, Fam59b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242915
Homologene: 19063
Zfp36
Name: zinc finger protein 36
Synonyms: Zfp-36, Nup475, Ttp, Tristetraprolin, Tis11
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22695
Homologene: 2558
Clip2
Name: CAP-GLY domain containing linker protein 2
Synonyms: Cyln2, CLIP-115, WSCR4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269713
HGNC: HGNC:2586
Homologene: 20718
Lair1
Name: leukocyte-associated Ig-like receptor 1
Synonyms: D7Bwg0421e, mLair-1, Lair-1, 5133400O11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 52855
Homologene: 48097
Fam184a
Name: family with sequence similarity 184, member A
Synonyms: 4930589M24Rik, 4930438C08Rik, 3110012E06Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75906
Homologene: 11600
Zswim9
Name: zinc finger SWIM-type containing 9
Synonyms: 6330408A02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 321008
Homologene: 52386
Fank1
Name: fibronectin type 3 and ankyrin repeat domains 1
Synonyms: 1700007B22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66930
Homologene: 12055
Gfra4
Name: glial cell line derived neurotrophic factor family receptor alpha 4
Synonyms: GFR alpha-4, G630015H18Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14588
Homologene: 10565
Arhgap27
Name: Rho GTPase activating protein 27
Synonyms: 2310069I04Rik, 5730442P18Rik, Sh3d20
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 544817
Homologene: 45715
Or6a2
Name: olfactory receptor family 6 subfamily A member 2
Synonyms: Olfr2, GA_x6K02T2PBJ9-9381439-9380456, I54, I7, MOR103-15, Olfr41
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18317
Homologene: 2743
Tubb2b
Name: tubulin, beta 2B class IIB
Synonyms: 2410129E14Rik, brdp
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73710
VEGA: 13
Homologene: 49734
Gabra4
Name: gamma-aminobutyric acid type A receptor subunit alpha 4
Synonyms: Gabra-4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14397
HGNC: HGNC:4078
Homologene: 631
Chst13
Name: carbohydrate sulfotransferase 13
Synonyms: Chst13, 1110067M19Rik, C4ST-3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 71797
Homologene: 44360
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Diet1, Gm13364, Gm13318
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Bambi
Name: BMP and activin membrane-bound inhibitor
Synonyms: 2610003H06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 68010
VEGA: 18
Homologene: 8215
Genetic Alterations
ENU-induced transitions at the following base pair locations:
  • A to T, chromosome 1 at 16,460,371 bp (GRCm38)
  • C to T, chromosome 1 at 34,180,443 bp (GRCm38)
  • T to A, chromosome 1 at 97,775,486 bp (GRCm38)
  • T to A, chromosome 1 at 155,242,209 bp (GRCm38)
  • T to A, chromosome 2 at 5,031,339 bp (GRCm38)
  • T to A, chromosome 2 at 15,620,590 bp (GRCm38)
  • C to T, chromosome 2 at 76,885,013 bp (GRCm38)
  • T to A, chromosome 2 at 115,674,755 bp (GRCm38)
  • C to A, chromosome 2 at 131,042,680 bp (GRCm38)
  • G to A, chromosome 3 at 5,390,446 bp (GRCm38)
  • G to A, chromosome 3 at 7,576,111 bp (GRCm38)
  • T to A, chromosome 3 at 60,595,665 bp (GRCm38)
  • AATCATC to AATC, chromosome 3 at 142,771,417 bp (GRCm38)
  • T to A, chromosome 3 at 146,454,354 bp (GRCm38)
  • T to C, chromosome 4 at 58,437,349 bp (GRCm38)
  • C to T, chromosome 5 at 30,114,221 bp (GRCm38)
  • T to A, chromosome 5 at 71,633,661 bp (GRCm38)
  • G to A, chromosome 5 at 110,318,000 bp (GRCm38)
  • C to T, chromosome 5 at 134,504,762 bp (GRCm38)
  • T to C, chromosome 5 at 147,189,867 bp (GRCm38)
  • T to C, chromosome 6 at 38,295,166 bp (GRCm38)
  • C to T, chromosome 6 at 42,597,090 bp (GRCm38)
  • C to T, chromosome 6 at 90,309,092 bp (GRCm38)
  • A to T, chromosome 7 at 4,010,795 bp (GRCm38)
  • T to A, chromosome 7 at 13,260,278 bp (GRCm38)
  • A to G, chromosome 7 at 26,200,834 bp (GRCm38)
  • A to T, chromosome 7 at 28,377,919 bp (GRCm38)
  • T to C, chromosome 7 at 43,501,271 bp (GRCm38)
  • A to T, chromosome 7 at 107,001,692 bp (GRCm38)
  • T to A, chromosome 7 at 133,862,158 bp (GRCm38)
  • T to A, chromosome 7 at 141,641,481 bp (GRCm38)
  • A to G, chromosome 8 at 70,242,778 bp (GRCm38)
  • T to A, chromosome 8 at 91,485,258 bp (GRCm38)
  • T to A, chromosome 10 at 53,750,768 bp (GRCm38)
  • A to G, chromosome 10 at 80,764,638 bp (GRCm38)
  • T to A, chromosome 10 at 128,308,354 bp (GRCm38)
  • T to A, chromosome 11 at 52,282,946 bp (GRCm38)
  • A to G, chromosome 11 at 103,339,222 bp (GRCm38)
  • T to A, chromosome 12 at 103,146,361 bp (GRCm38)
  • G to A, chromosome 13 at 15,725,801 bp (GRCm38)
  • T to C, chromosome 13 at 34,128,426 bp (GRCm38)
  • T to A, chromosome 13 at 55,313,705 bp (GRCm38)
  • C to A, chromosome 15 at 34,123,698 bp (GRCm38)
  • A to T, chromosome 17 at 30,959,350 bp (GRCm38)
  • T to C, chromosome 18 at 3,511,515 bp (GRCm38)
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9787 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
070032-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.