Strain Name:
C57BL/6J-MtgxR0094Btlr/Mmmh
Stock Number:
038380-MU
Citation ID:
RRID:MMRRC_038380-MU
Other Names:
R0094 (G1), C57BL/6J-MtgxR0094Btlr
Major Collection:

Strain Information

Pkd1
Name: polycystin 1, transient receptor potential channel interacting
Synonyms: PC-1, PC1, polycystin-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18763
VEGA: 17
HGNC: HGNC:9008
Homologene: 250
Dap3
Name: death associated protein 3
Synonyms: 4921514D13Rik, DAP-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 65111
HGNC: HGNC:2673
Homologene: 3404
Sptan1
Name: spectrin alpha, non-erythrocytic 1
Synonyms: alphaII-spectrin, 2610027H02Rik, Spna-2, Spna2, alpha-fodrin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20740
Homologene: 2353
B3gnt2
Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
Synonyms: B3Galt6, B3gnt1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 53625
Homologene: 4797
Mvd
Name: mevalonate (diphospho) decarboxylase
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 192156
HGNC: HGNC:7529
Homologene: 1843
Ndc80
Name: NDC80 kinetochore complex component
Synonyms: Kntc2, HEC1, 2610020P18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67052
VEGA: 17
Homologene: 38141
Ankrd12
Name: ankyrin repeat domain 12
Synonyms: 2900001A12Rik, ANCO-2, GAC-1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 106585
Homologene: 9059
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 2900005P22Rik, TRS130, 4632408O18Rik, Nibp, 1810044A24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Rpa2
Name: replication protein A2
Synonyms: 30-kDa protein, RPA34, Rf-A2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19891
Homologene: 37712
Ranbp3
Name: RAN binding protein 3
Synonyms: 2610024N24Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 71810
VEGA: 17
HGNC: HGNC:9850
Homologene: 136516
Ddias
Name: DNA damage-induced apoptosis suppressor
Synonyms: 4632434I11Rik, noxin
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 74041
Homologene: 51655
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Amotl1
Name: angiomotin-like 1
Synonyms: 2310067L22Rik, 4932416D09Rik, JEAP, 2310010G08Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 75723
Homologene: 43977
Ubr3
Name: ubiquitin protein ligase E3 component n-recognin 3
Synonyms: A130030D10Rik, Zfp650, 4833421P10Rik, 1110059H15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68795
Homologene: 52092
Ap5z1
Name: adaptor-related protein complex 5, zeta 1 subunit
Synonyms: C330006K01Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231855
Homologene: 18213
Cacna2d3
Name: calcium channel, voltage-dependent, alpha2/delta subunit 3
Synonyms: alpha 2 delta-3, alpha2delta3
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12294
Homologene: 74929
Cfap77
Name: cilia and flagella associated protein 77
Synonyms: LOC329375, 1700101E01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329375
Homologene: 45813
Dsg2
Name: desmoglein 2
Synonyms: D18Ertd293e
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13511
HGNC: HGNC:3049
Homologene: 1464
Noc3l
Name: NOC3 like DNA replication regulator
Synonyms: Fad24
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 57753
VEGA: 19
Homologene: 39642
Emc1
Name: ER membrane protein complex subunit 1
Synonyms: C230096C10Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230866
Homologene: 9002
Nbeal1
Name: neurobeachin like 1
Synonyms: A530050O19Rik, 2310076G13Rik, ALS2CR17, A530083I02Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 269198
Homologene: 16453
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 623474
Homologene: 8240
Tmem81
Name: transmembrane protein 81
Synonyms: 4930429O20Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74626
Homologene: 12579
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: Gm1027, Heatr8, LOC381538
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381538
Homologene: 19633
4930432E11Rik
Name: RIKEN cDNA 4930432E11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243900
Pkhd1
Name: polycystic kidney and hepatic disease 1
Synonyms: tigmin, FPC
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241035
HGNC: HGNC:9016
Homologene: 16336
Colgalt1
Name: collagen beta(1-O)galactosyltransferase 1
Synonyms: Glt25d1, 2810024B22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234407
Homologene: 23465
Sis
Name: sucrase isomaltase
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69983
Homologene: 37424
Ptpro
Name: protein tyrosine phosphatase receptor type O
Synonyms: D28, PTPROt, Ptpn15, PTP-oc, GLEPP1, PTP-U2, PTP-BK, PTP-phi
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Ppfia2
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
Synonyms: E130120L08Rik, Liprin-alpha2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 327814
VEGA: 10
HGNC: HGNC:9246
Homologene: 27953
Vmn1r213
Name: vomeronasal 1 receptor 213
Synonyms: V1rh6
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171249
Homologene: 110880
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Hfm1
Name: HFM1, ATP-dependent DNA helicase homolog
Synonyms: Mer3, LOC381663, Sec63d1, A330009G12Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330149
Homologene: 87103
Or14c40
Name: olfactory receptor family 14 subfamily C member 40
Synonyms: MOR221-3, GA_x6K02T2NHDJ-9457744-9456734, Olfr293
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 257906
Homologene: 79385
Ltbp2
Name: latent transforming growth factor beta binding protein 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16997
HGNC: HGNC:6715
Homologene: 369
Ahnak
Name: AHNAK nucleoprotein
Synonyms: DY6, 1110004P15Rik, 2310047C17Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66395
VEGA: 19
HGNC: HGNC:347
Homologene: 67425
Eif2b1
Name: eukaryotic translation initiation factor 2B, subunit alpha
Synonyms: EIF2B, EIF2BA, D5Ertd406e, 26kDa
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 209354
HGNC: HGNC:3257
Homologene: 1080
Gypa
Name: glycophorin A
Synonyms: GPA, CD235a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14934
Vmn2r59
Name: vomeronasal 2, receptor 59
Synonyms: EG628444
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 628444
Homologene: 129683
Spp2
Name: secreted phosphoprotein 2
Synonyms: spp24, 0610038O04Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75396
Homologene: 5058
Spata45
Name: spermatogenesis associated 45
Synonyms: 1700022P22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75558
Homologene: 52729
Serping1
Name: serine (or cysteine) peptidase inhibitor, clade G, member 1
Synonyms: C1 inhibitor, C1nh, C1INH
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12258
HGNC: HGNC:1228
Homologene: 44
Sirpb1c
Name: signal-regulatory protein beta 1C
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 100038947
Homologene: 82993
Otol1
Name: otolin 1
Synonyms: LOC229389, Gm414
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229389
Homologene: 19018
1700006A11Rik
Name: RIKEN cDNA 1700006A11 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71824
Frmpd1
Name: FERM and PDZ domain containing 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 666060
Homologene: 8939
Dcdc2b
Name: doublecortin domain containing 2b
Synonyms: LOC384062, Gm12964
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100504491
Homologene: 82651
Slc34a2
Name: solute carrier family 34 (sodium phosphate), member 2
Synonyms: D5Ertd227e, NaPi-2b, type IIb Na/Picotransporter, Npt2b
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20531
Homologene: 2297
Dtx1
Name: deltex 1, E3 ubiquitin ligase
Synonyms: Fxit1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14357
HGNC: HGNC:3060
Homologene: 74522
Mfap5
Name: microfibrillar associated protein 5
Synonyms: MAGP-2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50530
Homologene: 2599
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
4931429L15Rik
Name: RIKEN cDNA 4931429L15 gene
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74361
Homologene: 86847
Ss18l2
Name: SS18, nBAF chromatin remodeling complex subunit like 2
Synonyms: Band 47B, 1110020I04Rik, Deb1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 26901
VEGA: 9
Homologene: 32307
1700017N19Rik
Name: RIKEN cDNA 1700017N19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 66605
Homologene: 45135
Pigs
Name: phosphatidylinositol glycan anchor biosynthesis, class S
Synonyms: LOC276846, LOC245087
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 276846
Homologene: 41963
Ctsj
Name: cathepsin J
Synonyms: CatRLP, Cat P, CATP, Ctsp, rat gene/Cathepsin L-related protein
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 26898
VEGA: 13
Homologene: 137246
Pcdh8
Name: protocadherin 8
Synonyms: 1700080P15Rik, Papc
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 18530
HGNC: HGNC:8660
Homologene: 1943
Rfc4
Name: replication factor C (activator 1) 4
Synonyms: RFC37, A1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106344
HGNC: HGNC:9972
Homologene: 6288
Lipg
Name: lipase, endothelial
Synonyms: EL, 3110013K01Rik, mEDL, endothelial lipase
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 16891
VEGA: 18
HGNC: HGNC:6623
Homologene: 21218
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 20,209,246 bp
  • T to A, chromosome 1 at 60,305,309 bp
  • T to A, chromosome 1 at 88,420,680 bp
  • A to G, chromosome 1 at 132,508,049 bp
  • A to G, chromosome 1 at 191,039,862 bp
  • A to T, chromosome 2 at 28,984,434 bp
  • T to C, chromosome 2 at 30,006,623 bp
  • T to C, chromosome 2 at 41,282,030 bp
  • C to T, chromosome 2 at 69,951,362 bp
  • T to G, chromosome 2 at 84,773,276 bp
  • G to T, chromosome 3 at 15,838,758 bp
  • G to A, chromosome 3 at 70,018,683 bp
  • A to T, chromosome 3 at 72,921,437 bp
  • T to A, chromosome 3 at 88,927,028 bp
  • T to C, chromosome 3 at 124,409,778 bp
  • T to C, chromosome 4 at 11,599,681 bp
  • C to A, chromosome 4 at 45,284,899 bp
  • C to T, chromosome 4 at 106,703,184 bp
  • T to C, chromosome 4 at 129,610,311 bp
  • T to C, chromosome 4 at 132,770,582 bp
  • T to A, chromosome 4 at 139,360,485 bp
  • T to C, chromosome 5 at 53,063,968 bp
  • T to A, chromosome 5 at 106,917,478 bp
  • A to G, chromosome 5 at 120,682,624 bp
  • A to G, chromosome 5 at 124,571,766 bp
  • G to A, chromosome 5 at 142,476,812 bp
  • G to A, chromosome 6 at 122,525,992 bp
  • T to C, chromosome 6 at 137,386,352 bp
  • A to G, chromosome 7 at 29,560,811 bp
  • T to C, chromosome 7 at 42,012,298 bp
  • A to G, chromosome 7 at 44,516,904 bp
  • A to G, chromosome 7 at 86,664,294 bp
  • T to C, chromosome 7 at 92,859,900 bp
  • T to C, chromosome 8 at 71,623,158 bp
  • T to A, chromosome 8 at 80,500,931 bp
  • C to T, chromosome 8 at 122,439,703 bp
  • A to G, chromosome 9 at 14,575,387 bp
  • T to A, chromosome 9 at 46,306,886 bp
  • T to C, chromosome 9 at 121,712,633 bp
  • A to G, chromosome 10 at 100,603,494 bp
  • G to A, chromosome 10 at 106,859,812 bp
  • T to C, chromosome 11 at 22,836,655 bp
  • C to T, chromosome 11 at 72,817,965 bp
  • T to A, chromosome 11 at 78,340,038 bp
  • A to G, chromosome 12 at 84,799,426 bp
  • A to G, chromosome 13 at 23,011,649 bp
  • A to C, chromosome 13 at 61,003,705 bp
  • C to T, chromosome 14 at 29,170,503 bp
  • G to T, chromosome 14 at 79,768,148 bp
  • A to T, chromosome 15 at 72,894,929 bp
  • G to T, chromosome 16 at 23,115,428 bp
  • A to G, chromosome 17 at 24,581,276 bp
  • A to G, chromosome 17 at 56,709,338 bp
  • A to T, chromosome 17 at 65,970,176 bp
  • A to G, chromosome 17 at 71,520,939 bp
  • A to T, chromosome 18 at 20,591,853 bp
  • T to C, chromosome 18 at 74,945,846 bp
  • T to A, chromosome 19 at 9,013,893 bp
  • T to C, chromosome 19 at 38,795,166 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0094 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038380-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.