Strain Name:
C57BL/6J-MtgxR0725Btlr/Mmmh
Stock Number:
038907-MU
Citation ID:
RRID:MMRRC_038907-MU
Other Names:
R0725 (G1), C57BL/6J-MtgxR0725Btlr
Major Collection:

Strain Information

Cep55
Name: centrosomal protein 55
Synonyms: 2700032M20Rik, 1200008O12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74107
VEGA: 19
HGNC: HGNC:1161
Homologene: 10019
Pcm1
Name: pericentriolar material 1
Synonyms: C030044G17Rik, 9430077F19Rik, 2600002H09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 321003
Stx12
Name: syntaxin 12
Synonyms: Stx13, syntaxin 13
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100226
Homologene: 128192
Nfyc
Name: nuclear transcription factor-Y gamma
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 18046
HGNC: HGNC:7806
Homologene: 7440
Kntc1
Name: kinetochore associated 1
Synonyms: jgl
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 208628
Homologene: 32227
Osbpl8
Name: oxysterol binding protein-like 8
Synonyms: D330025H14Rik, ORP-8
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 237542
VEGA: 10
Homologene: 68813
Ncbp1
Name: nuclear cap binding protein subunit 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 433702
HGNC: HGNC:7658
Homologene: 1859
Pdcd11
Name: programmed cell death 11
Synonyms: 1110021I22Rik, ALG-4
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18572
VEGA: 19
Homologene: 74968
Clptm1l
Name: CLPTM1-like
Synonyms: C130052I12Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218335
VEGA: 13
Homologene: 12767
Ccnk
Name: cyclin K
Synonyms: CPR4, CycK
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12454
VEGA: 12
HGNC: HGNC:1596
Homologene: 14748
Crygb
Name: crystallin, gamma B
Synonyms: DGcry-3, Cryg-3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12965
HGNC: HGNC:2409
Homologene: 3816
Dock7
Name: dedicator of cytokinesis 7
Synonyms: 3110056M06Rik, LOC242555, m
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 67299
Homologene: 23566
Atp13a3
Name: ATPase type 13A3
Synonyms: LOC224087, LOC224088, LOC385637
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224088
Homologene: 23455
Rbm33
Name: RNA binding motif protein 33
Synonyms: 3200001K10Rik, 6430512A10Rik, Prr8
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381626
Homologene: 137386
Fgfrl1
Name: fibroblast growth factor receptor-like 1
Synonyms: FGFR5gamma, FGFR5beta, FGFR5, fibroblast growth factor receptor 5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 116701
HGNC: HGNC:3693
Homologene: 11067
Muc20
Name: mucin 20
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224116
Homologene: 17135
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: Dnchc2, m152Asp, m407Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, 4432416O06Rik, DHC1b, DHC2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Vezf1
Name: vascular endothelial zinc finger 1
Synonyms: db1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 22344
Homologene: 5175
Asph
Name: aspartate-beta-hydroxylase
Synonyms: aspartyl beta-hydroxylase, calsequestrin-binding protein, BAH, jumbug, 3110001L23Rik, junctate, cI-37, Junctin, 2310005F16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 65973
HGNC: HGNC:757
Homologene: 20910
Gzf1
Name: GDNF-inducible zinc finger protein 1
Synonyms: 8430437G08Rik, Zfp336
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74533
Homologene: 11200
Cpped1
Name: calcineurin-like phosphoesterase domain containing 1
Synonyms: C530044N13Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 223978
Homologene: 10142
Heatr5b
Name: HEAT repeat containing 5B
Synonyms: 2010013B10Rik, A230048G03Rik, D330050P16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 320473
VEGA: 17
Homologene: 25536
Zfp287
Name: zinc finger protein 287
Synonyms: B230333C16Rik, SKAT-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 170740
Homologene: 23244
Pkp1
Name: plakophilin 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18772
HGNC: HGNC:9023
Homologene: 253
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Ush2a
Name: usherin
Synonyms: MUSH2A, LOC269160, Ush2a, A930037M10Rik, A930011D15Rik, LOC381317, Ushrn
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 22283
Homologene: 66151
Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13120
HGNC: HGNC:2644
Homologene: 128045
Cacna1s
Name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Synonyms: Cchl1a3, Cav1.1, muscle dysgenesis, DHPR alpha1s, mdg, sj, fmd
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12292
HGNC: HGNC:1397
Homologene: 37257
Slc3a1
Name: solute carrier family 3, member 1
Synonyms: NTAA, D2H
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20532
VEGA: 17
Homologene: 37289
Macc1
Name: metastasis associated in colon cancer 1
Synonyms: 4732474O15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238455
Homologene: 18813
Selenbp2
Name: selenium binding protein 2
Synonyms: AP56, Lpsb2, acetaminophen-binding protein
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20342
Homologene: 2930
Yipf2
Name: Yip1 domain family, member 2
Synonyms: 1300010K09Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74766
VEGA: 9
Homologene: 23430
Tas2r125
Name: taste receptor, type 2, member 125
Synonyms: mt2r59, mGR25, T2R26, Tas2r25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387352
Homologene: 87294
Cfap300
Name: cilia and flagella associated protein 300
Synonyms: 9230110C19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234912
VEGA: 9
Homologene: 13163
Tmed11
Name: transmembrane p24 trafficking protein 11
Synonyms: 1810008K16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67366
Homologene: 48721
Psmc4
Name: proteasome (prosome, macropain) 26S subunit, ATPase, 4
Synonyms: CIP21, CAR interacting protein 21, MIP224
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 23996
HGNC: HGNC:9551
Homologene: 4744
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 65020
Homologene: 129707
Dsel
Name: dermatan sulfate epimerase-like
Synonyms: 9330132E09Rik, DS-epi2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 319901
Homologene: 12964
Niban1
Name: niban apoptosis regulator 1
Synonyms: Niban, Fam129a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 63913
Homologene: 62170
Or51f5
Name: olfactory receptor family 51 subfamily F member 5
Synonyms: GA_x6K02T2PBJ9-5491151-5492095, MOR14-2, Olfr561
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259096
Homologene: 133029
Cfh
Name: complement component factor h
Synonyms: Mud-1, Sas-1, Sas1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Tchp
Name: trichoplein, keratin filament binding
Synonyms: A930031F18Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 77832
Homologene: 12686
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 636808
Homologene: 43974
Dll4
Name: delta like canonical Notch ligand 4
Synonyms: Delta4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 54485
HGNC: HGNC:2910
Homologene: 10411
Cyp3a25
Name: cytochrome P450, family 3, subfamily a, polypeptide 25
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56388
Homologene: 135775
Mpp4
Name: membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
Synonyms: DLG6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 227157
Homologene: 23296
Nfxl1
Name: nuclear transcription factor, X-box binding-like 1
Synonyms: D430033A06Rik, TCF9, 1700012H24Rik, LOC381696
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100978
Homologene: 26752
Or8g55
Name: olfactory receptor family 8 subfamily G member 55
Synonyms: MOR171-17, Olfr972, GA_x6K02T2PVTD-33572803-33573747
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258603
VEGA: 9
Homologene: 121532
Fam167b
Name: family with sequence similarity 167, member B
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230766
Homologene: 13085
4930562F07Rik
Name: RIKEN cDNA 4930562F07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75255
Pigm
Name: phosphatidylinositol glycan anchor biosynthesis, class M
Synonyms: C920011G20Rik, 4933437L05Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67556
Homologene: 6274
Pheta1
Name: PH domain containing endocytic trafficking adaptor 1
Synonyms: Fam109a, Ses1, A230106M15Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231717
Homologene: 16966
Pex12
Name: peroxisomal biogenesis factor 12
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103737
HGNC: HGNC:8854
Homologene: 240
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 59,121,422 bp
  • T to C, chromosome 1 at 65,081,941 bp
  • T to C, chromosome 1 at 111,859,952 bp
  • A to G, chromosome 1 at 116,292,476 bp
  • G to T, chromosome 1 at 135,880,740 bp
  • T to C, chromosome 1 at 136,098,526 bp
  • A to G, chromosome 1 at 140,157,343 bp
  • A to G, chromosome 1 at 151,706,015 bp
  • A to G, chromosome 1 at 160,077,483 bp
  • A to G, chromosome 1 at 172,376,817 bp
  • G to A, chromosome 1 at 188,951,525 bp
  • C to T, chromosome 2 at 76,748,310 bp
  • T to C, chromosome 2 at 119,332,689 bp
  • C to T, chromosome 2 at 148,684,649 bp
  • G to T, chromosome 3 at 94,697,502 bp
  • C to T, chromosome 4 at 9,542,275 bp
  • A to G, chromosome 4 at 46,152,056 bp
  • T to C, chromosome 4 at 98,945,291 bp
  • T to C, chromosome 4 at 115,626,827 bp
  • G to T, chromosome 4 at 120,768,734 bp
  • C to A, chromosome 4 at 129,578,285 bp
  • A to C, chromosome 4 at 132,857,390 bp
  • T to C, chromosome 5 at 28,394,483 bp
  • A to T, chromosome 5 at 72,559,130 bp
  • T to A, chromosome 5 at 108,704,673 bp
  • T to A, chromosome 5 at 108,778,989 bp
  • C to A, chromosome 5 at 114,719,621 bp
  • T to A, chromosome 5 at 121,853,251 bp
  • T to C, chromosome 5 at 123,769,704 bp
  • A to G, chromosome 5 at 145,994,936 bp
  • G to T, chromosome 6 at 132,910,122 bp
  • A to T, chromosome 7 at 12,836,363 bp
  • T to C, chromosome 7 at 28,048,862 bp
  • T to A, chromosome 7 at 102,774,532 bp
  • G to C, chromosome 8 at 41,287,811 bp
  • C to A, chromosome 9 at 7,015,497 bp
  • A to T, chromosome 9 at 8,027,143 bp
  • G to C, chromosome 9 at 21,592,223 bp
  • A to T, chromosome 9 at 39,873,347 bp
  • T to C, chromosome 10 at 111,286,240 bp
  • A to T, chromosome 11 at 62,714,213 bp
  • G to T, chromosome 11 at 83,298,034 bp
  • T to C, chromosome 11 at 88,073,330 bp
  • T to C, chromosome 12 at 108,195,575 bp
  • C to A, chromosome 12 at 119,447,516 bp
  • A to G, chromosome 13 at 73,606,343 bp
  • T to C, chromosome 15 at 81,430,842 bp
  • C to A, chromosome 16 at 11,828,450 bp
  • T to C, chromosome 16 at 30,351,387 bp
  • C to T, chromosome 16 at 32,793,488 bp
  • T to A, chromosome 17 at 78,796,396 bp
  • G to A, chromosome 17 at 85,060,835 bp
  • T to C, chromosome 19 at 38,060,174 bp
  • A to G, chromosome 19 at 47,127,291 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0725 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
038907-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.