Strain Name:
C57BL/6J-MtgxR0885Btlr/Mmmh
Stock Number:
039052-MU
Citation ID:
RRID:MMRRC_039052-MU
Other Names:
R0885 (G1), C57BL/6J-MtgxR0885Btlr
Major Collection:

Strain Information

Kif3c
Name: kinesin family member 3C
Synonyms: N-4 kinesin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 16570
VEGA: 12
HGNC: HGNC:6321
Homologene: 55640
Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: Todo, Gena 52, GENA 60, Dz, Cycn, Cyn, Obt, Mt, Whi, GENA 47, A730019I05Rik, Lda, Flo, Edy, WBE1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 320790
Homologene: 19067
Epha4
Name: Eph receptor A4
Synonyms: Cek8, Sek, Tyro1, Hek8, 2900005C20Rik, Sek1, rb
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13838
HGNC: HGNC:3388
Homologene: 20933
Lrp2
Name: low density lipoprotein receptor-related protein 2
Synonyms: b2b1625.2Clo, D230004K18Rik, Megalin, Gp330
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14725
HGNC: HGNC:6694
Homologene: 20952
Atm
Name: ataxia telangiectasia mutated
Synonyms: C030026E19Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11920
HGNC: HGNC:795
Homologene: 30952
Fryl
Name: FRY like transcription coactivator
Synonyms: 2310004H21Rik, 9030227G01Rik, 2510002A14Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72313
Homologene: 103956
Ptpn5
Name: protein tyrosine phosphatase, non-receptor type 5
Synonyms: Step
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19259
HGNC: HGNC:9657
Homologene: 8423
Xpnpep3
Name: X-prolyl aminopeptidase 3, mitochondrial
Synonyms: E430012M05Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 321003
Spop
Name: speckle-type BTB/POZ protein
Synonyms: TEF2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20747
Homologene: 68354
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20111
Homologene: 55703
Asxl2
Name: ASXL transcriptional regulator 2
Synonyms: 4930556B16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 75302
Homologene: 10102
Tubgcp5
Name: tubulin, gamma complex component 5
Synonyms: GCP5, B130010C12Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233276
Homologene: 14172
Tle1
Name: transducin-like enhancer of split 1
Synonyms: Grg1, Estm14, C230057C06Rik, Tle4l
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 21885
Homologene: 21058
Atp2c1
Name: ATPase, Ca++-sequestering
Synonyms: 1700121J11Rik, PMR1, D930003G21Rik, ATP2C1A, SPCA
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235574
Homologene: 56672
Mrpl47
Name: mitochondrial ribosomal protein L47
Synonyms: NCM1, CGI-204, 4833424P18Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 74600
Homologene: 32475
Grb10
Name: growth factor receptor bound protein 10
Synonyms: Meg1, 5730571D09Rik, maternally expressed gene 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14783
HGNC: HGNC:4564
Homologene: 3882
Phip
Name: pleckstrin homology domain interacting protein
Synonyms: Wdr11, 2810004D21Rik, 4632404O06Rik, Ndrp
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83946
Homologene: 41209
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Tcof1
Name: treacle ribosome biogenesis factor 1
Synonyms: treacle
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 21453
Homologene: 68049
Rttn
Name: rotatin
Synonyms: 4921538A15Rik, C530033I08Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 246102
VEGA: 18
Homologene: 65275
Wdr37
Name: WD repeat domain 37
Synonyms: 3110035P10Rik, 4933417A01Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 207615
Homologene: 40914
Mmp16
Name: matrix metallopeptidase 16
Synonyms: MT3-MMP, Membrane type 3-MMP
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17389
HGNC: HGNC:7162
Homologene: 55939
Prmt2
Name: protein arginine N-methyltransferase 2
Synonyms: Hrmt1l1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 15468
HGNC: HGNC:5186
Homologene: 55587
Naca
Name: nascent polypeptide-associated complex alpha polypeptide
Synonyms: LOC380777, skNAC
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17938
VEGA: 10
HGNC: HGNC:7629
Homologene: 136025
Ebf3
Name: early B cell factor 3
Synonyms: 3110018A08Rik, Olf-1/EBF-like 2, O/E-2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13593
Homologene: 56472
Adam18
Name: a disintegrin and metallopeptidase domain 18
Synonyms: Dtgn3, Adam27
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 13524
HGNC: HGNC:196
Homologene: 74941
Il20
Name: interleukin 20
Synonyms: Zcyto10
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 58181
HGNC: HGNC:6002
Homologene: 10286
Mcm6
Name: minichromosome maintenance complex component 6
Synonyms: D1Wsu22e, Mcmd6
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 17219
HGNC: HGNC:6949
Homologene: 4322
Mpdz
Name: multiple PDZ domain crumbs cell polarity complex component
Synonyms: multiple PDZ domain protein, B930003D11Rik, MUPP1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 17475
HGNC: HGNC:7208
Homologene: 2841
Cpq
Name: carboxypeptidase Q
Synonyms: Lal-1, Pgcp, 1190003P12Rik, HLS2, 2610034C17Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54381
VEGA: 15
Homologene: 9401
Plxna2
Name: plexin A2
Synonyms: OCT, Plxn2, 2810428A13Rik, PlexA2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 18845
HGNC: HGNC:9100
Homologene: 56427
Adam20
Name: a disintegrin and metallopeptidase domain 20
Synonyms: 4930529F22Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 384806
HGNC: HGNC:199
Homologene: 128364
Ubxn10
Name: UBX domain protein 10
Synonyms: Ubxd3, 5730509E04Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 212190
Homologene: 17568
Myo6
Name: myosin VI
Synonyms: Myo6rsv, rsv, Tlc
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17920
HGNC: HGNC:7605
Homologene: 56417
Ciita
Name: class II transactivator
Synonyms: Gm9475, C2ta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12265
VEGA: 16
HGNC: HGNC:7067
Homologene: 207
Sis
Name: sucrase isomaltase
Synonyms: sucrase-isomaltase, 2010204N08Rik, Si-s
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69983
Homologene: 37424
Pip4p1
Name: phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
Synonyms: Tmem55b
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 219024
Homologene: 10279
Des
Name: desmin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 13346
HGNC: HGNC:2770
Homologene: 56469
Dclk1
Name: doublecortin-like kinase 1
Synonyms: Click-I, 1700113D08Rik, Dcl, DCLK, CPG16, Dcamkl1, 2810480F11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Raet1c
Name: retinoic acid early transcript gamma
Synonyms: Rae1c, RAE-1gamma
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Dll1
Name: delta like canonical Notch ligand 1
Synonyms: Delta1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13388
HGNC: HGNC:2908
Homologene: 4104
Ppp1r16a
Name: protein phosphatase 1, regulatory subunit 16A
Synonyms: Mypt3, 2900084E10Rik, R75527
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 73062
Homologene: 13161
Caskin1
Name: CASK interacting protein 1
Synonyms: 3300002N10Rik, C630036E02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 268932
VEGA: 17
Homologene: 25873
Pxdn
Name: peroxidasin
Synonyms: VPO1, 2310075M15Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 69675
Homologene: 33907
Cyp2d40
Name: cytochrome P450, family 2, subfamily d, polypeptide 40
Synonyms: 1300013D18Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71754
VEGA: 15
Homologene: 135470
Matn2
Name: matrilin 2
Synonyms: Crtm2
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17181
VEGA: 15
HGNC: HGNC:6908
Homologene: 20538
Dubr
Name: Dppa2 upstream binding RNA
Synonyms: 5330426P16Rik, Dum
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 68190
Psme3ip1
Name: proteasome activator subunit 3 interacting protein 1
Synonyms: 2310065K24Rik, 1700001O11Rik, Fam192a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102122
Homologene: 11797
Serpinb9b
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9b
Synonyms: ovalbumin, SPI-CI, 1600019A21Rik, Spi10, R86
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20706
HGNC: HGNC:8955
Homologene: 137240
Prag1
Name: PEAK1 related kinase activating pseudokinase 1
Synonyms: D8Ertd82e, NACK
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244418
Homologene: 18256
Ugt2b36
Name: UDP glucuronosyltransferase 2 family, polypeptide B36
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231396
Homologene: 128251
Slco2a1
Name: solute carrier organic anion transporter family, member 2a1
Synonyms: mPgt, Slc21a2, 2310021C19Rik, Pgt
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 24059
Homologene: 38077
Mrgprb3
Name: MAS-related GPR, member B3
Synonyms: MrgB3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 404238
Homologene: 138632
Or2ak6
Name: olfactory receptor family 2 subfamily AK member 6
Synonyms: MOR285-2, Olfr319, GA_x6K02T2NKPP-708319-707399
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258493
Spata4
Name: spermatogenesis associated 4
Synonyms: SRG2, 1700001N01Rik, TSARG2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 69281
Homologene: 15868
Ptgds
Name: prostaglandin D2 synthase (brain)
Synonyms: L-PGDS, PGD2, Ptgs3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19215
HGNC: HGNC:9592
Homologene: 737
Ambp
Name: alpha 1 microglobulin/bikunin precursor
Synonyms: Intin4, UTI, ulinastatin, ASPI, HI-30, Itil, Urinary Trypsin Inhibitor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 11699
HGNC: HGNC:453
Homologene: 1234
Zfp593
Name: zinc finger protein 593
Synonyms: 3110024A21Rik, E130106C14Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 68040
Homologene: 41070
1700020L13Rik
Name: RIKEN cDNA 1700020L13 gene
Synonyms: Thap8, 1700020L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108167416
Art1
Name: ADP-ribosyltransferase 1
Synonyms: Yac-1, ADPRT
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11870
HGNC: HGNC:723
Homologene: 128621
Lin28b
Name: lin-28 homolog B
Synonyms: 2810403D23Rik, D030047M17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 380669
VEGA: 10
Homologene: 47607
AC166823.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Lhfpl5
Name: lipoma HMGIC fusion partner-like 5
Synonyms: 9330179O15Rik, Tmhs
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 328789
Homologene: 18794
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 75,360,730 bp
  • A to G, chromosome 1 at 77,382,939 bp
  • T to C, chromosome 1 at 128,348,933 bp
  • T to C, chromosome 1 at 130,910,781 bp
  • T to C, chromosome 1 at 194,644,556 bp
  • T to C, chromosome 2 at 25,467,345 bp
  • A to T, chromosome 2 at 69,482,353 bp
  • T to C, chromosome 3 at 32,730,186 bp
  • G to T, chromosome 3 at 55,487,307 bp
  • G to A, chromosome 3 at 72,911,949 bp
  • T to A, chromosome 4 at 8,866,432 bp
  • A to T, chromosome 4 at 18,054,491 bp
  • A to G, chromosome 4 at 63,151,468 bp
  • A to G, chromosome 4 at 72,169,084 bp
  • T to A, chromosome 4 at 81,369,592 bp
  • C to T, chromosome 4 at 133,872,016 bp
  • A to G, chromosome 4 at 134,244,913 bp
  • A to T, chromosome 4 at 138,720,570 bp
  • A to T, chromosome 5 at 73,089,196 bp
  • T to A, chromosome 5 at 87,091,989 bp
  • T to A, chromosome 7 at 30,280,669 bp
  • T to C, chromosome 7 at 47,088,611 bp
  • C to A, chromosome 7 at 48,643,096 bp
  • T to A, chromosome 7 at 55,806,055 bp
  • T to C, chromosome 7 at 102,107,334 bp
  • T to C, chromosome 7 at 137,225,884 bp
  • T to C, chromosome 8 at 24,651,786 bp
  • T to C, chromosome 8 at 36,103,267 bp
  • T to A, chromosome 8 at 40,796,558 bp
  • C to T, chromosome 8 at 54,600,844 bp
  • C to A, chromosome 8 at 94,575,779 bp
  • T to C, chromosome 9 at 53,459,823 bp
  • T to C, chromosome 9 at 80,242,221 bp
  • C to A, chromosome 9 at 82,875,395 bp
  • G to T, chromosome 9 at 103,082,383 bp
  • C to T, chromosome 9 at 105,421,573 bp
  • T to A, chromosome 10 at 22,182,087 bp
  • C to T, chromosome 10 at 45,381,228 bp
  • A to G, chromosome 10 at 76,222,565 bp
  • C to A, chromosome 10 at 128,040,179 bp
  • G to A, chromosome 11 at 11,970,411 bp
  • C to T, chromosome 11 at 58,702,087 bp
  • T to C, chromosome 11 at 95,470,627 bp
  • A to G, chromosome 11 at 107,043,791 bp
  • A to T, chromosome 12 at 3,365,981 bp
  • C to A, chromosome 12 at 3,501,458 bp
  • G to A, chromosome 12 at 30,003,402 bp
  • A to C, chromosome 13 at 8,835,252 bp
  • T to C, chromosome 13 at 33,037,968 bp
  • T to C, chromosome 14 at 50,930,306 bp
  • A to C, chromosome 14 at 52,753,459 bp
  • T to C, chromosome 15 at 33,466,727 bp
  • T to A, chromosome 15 at 34,316,605 bp
  • C to T, chromosome 15 at 76,693,669 bp
  • T to A, chromosome 15 at 81,416,008 bp
  • T to C, chromosome 15 at 82,760,915 bp
  • A to T, chromosome 16 at 10,501,923 bp
  • G to T, chromosome 16 at 50,732,564 bp
  • A to T, chromosome 17 at 15,371,677 bp
  • G to A, chromosome 17 at 24,505,694 bp
  • A to T, chromosome 17 at 28,576,037 bp
  • A to T, chromosome 18 at 60,835,850 bp
  • A to G, chromosome 18 at 88,983,810 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0885 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039052-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.