Strain Name:
C57BL/6J-MtgxR1324Btlr/Mmmh
Stock Number:
039390-MU
Citation ID:
RRID:MMRRC_039390-MU
Other Names:
R1324 (G1), C57BL/6J-MtgxR1324Btlr
Major Collection:

Strain Information

Akap10
Name: A kinase anchor protein 10
Synonyms: D-AKAP2, 1500031L16Rik, B130049N18Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56697
HGNC: HGNC:368
Homologene: 32452
Serpinb6a
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6a
Synonyms: 4930482L21Rik, D330015H01Rik, Spi3, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20719
HGNC: HGNC:8950
Homologene: 20956
Usp25
Name: ubiquitin specific peptidase 25
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 30940
VEGA: 16
Homologene: 8374
Utp4
Name: UTP4 small subunit processome component
Synonyms: Tex292, TEG-292, Cirh1a
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21771
HGNC: HGNC:1983
Homologene: 40775
Tmem39a
Name: transmembrane protein 39a
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67846
Homologene: 9985
Lmnb2
Name: lamin B2
Synonyms: lamin B3
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16907
HGNC: HGNC:6638
Homologene: 7818
Ipo9
Name: importin 9
Synonyms: Imp9, 0710008K06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226432
Homologene: 5874
Add3
Name: adducin 3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 27360
VEGA: 19
HGNC: HGNC:245
Homologene: 40893
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: Nrbp, B230344L17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Fem1c
Name: fem 1 homolog c
Synonyms: 2610312A07Rik, 3632443A22Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240263
Homologene: 10606
Thoc6
Name: THO complex 6
Synonyms: Wdr58, F830014G06Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 386612
Homologene: 11533
Enam
Name: enamelin
Synonyms: abte
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13801
HGNC: HGNC:3344
Homologene: 9698
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Kif21a
Name: kinesin family member 21A
Synonyms: N-5 kinesin
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16564
VEGA: 15
Homologene: 56761
Nrxn3
Name: neurexin III
Synonyms: neurexin III beta, neurexin III alpha, D12Bwg0831e, neurexin III alpha, 9330112C09Rik, neurexin III beta, 4933401A11Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18191
HGNC: HGNC:8010
Homologene: 83225
Myom1
Name: myomesin 1
Synonyms: skelemin, D430047A17Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17929
VEGA: 17
HGNC: HGNC:7613
Homologene: 31196
Col11a1
Name: collagen, type XI, alpha 1
Synonyms: C530001D20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12814
HGNC: HGNC:2186
Homologene: 56389
Gjb3
Name: gap junction protein, beta 3
Synonyms: Cx31, connexin 31, Cnx31, Gjb-3, D4Wsu144e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14620
HGNC: HGNC:4285
Homologene: 7338
Fbxw15
Name: F-box and WD-40 domain protein 15
Synonyms: Fbxo12J
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382105
Homologene: 110776
Pheta2
Name: PH domain containing endocytic trafficking adaptor 2
Synonyms: Ses2, C920005C14Rik, Fam109b
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 338368
Homologene: 18578
Rnf141
Name: ring finger protein 141
Synonyms: 2610110L04Rik, ZFP36, ZNF230
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67150
Homologene: 9503
Negr1
Name: neuronal growth regulator 1
Synonyms: neurotractin, 5330422G01Rik, Ntra
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320840
Homologene: 41447
AC125117.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 135,406,870 bp
  • T to C, chromosome 2 at 76,781,586 bp
  • A to G, chromosome 3 at 114,030,916 bp
  • C to T, chromosome 3 at 157,069,223 bp
  • G to A, chromosome 4 at 127,326,431 bp
  • T to A, chromosome 5 at 31,245,813 bp
  • A to T, chromosome 5 at 88,494,068 bp
  • G to A, chromosome 7 at 110,816,843 bp
  • T to C, chromosome 8 at 106,898,265 bp
  • G to A, chromosome 9 at 109,558,246 bp
  • T to C, chromosome 10 at 80,904,171 bp
  • T to A, chromosome 11 at 61,915,021 bp
  • T to C, chromosome 12 at 89,254,696 bp
  • A to T, chromosome 13 at 33,918,360 bp
  • A to G, chromosome 14 at 51,315,845 bp
  • A to G, chromosome 15 at 82,343,498 bp
  • A to T, chromosome 15 at 90,948,322 bp
  • T to A, chromosome 16 at 38,573,169 bp
  • T to A, chromosome 16 at 77,080,387 bp
  • G to T, chromosome 17 at 23,677,463 bp
  • T to A, chromosome 17 at 71,052,719 bp
  • A to G, chromosome 18 at 46,506,401 bp
  • T to A, chromosome 19 at 53,233,188 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1324 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039390-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.