Strain Name:
C57BL/6J-MtgxR1540Btlr/Mmmh
Stock Number:
039579-MU
Citation ID:
RRID:MMRRC_039579-MU
Other Names:
R1540 (G1), C57BL/6J-MtgxR1540Btlr
Major Collection:

Strain Information

Ntsr1
Name: neurotensin receptor 1
Synonyms: Ntsr1, NTR-1, NT-1R, NTR1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18216
HGNC: HGNC:8039
Homologene: 68261
Lyst
Name: lysosomal trafficking regulator
Synonyms: D13Sfk13
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17101
VEGA: 13
HGNC: HGNC:1968
Homologene: 61
Cacna1g
Name: calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms: a1G, Cav3.1d
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12291
HGNC: HGNC:1394
Homologene: 22544
Glt8d1
Name: glycosyltransferase 8 domain containing 1
Synonyms: 2410004H05Rik, 5430414N14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 76485
VEGA: 14
Homologene: 32720
Il17rd
Name: interleukin 17 receptor D
Synonyms: 2810004A10Rik, Sef-S, Sef
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 171463
VEGA: 14
Homologene: 9717
Tmem59l
Name: transmembrane protein 59-like
Synonyms: 5330410G16Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 67937
Homologene: 8104
Id3
Name: inhibitor of DNA binding 3
Synonyms: Idb3, bHLHb25, HLH462
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 15903
HGNC: HGNC:5362
Homologene: 1633
Kcnc4
Name: potassium voltage gated channel, Shaw-related subfamily, member 4
Synonyms: Kcr2-4, Kv3.4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99738
HGNC: HGNC:6236
Homologene: 68427
Rps6ka2
Name: ribosomal protein S6 kinase, polypeptide 2
Synonyms: D17Wsu134e, Rps6ka-rs1, Rsk3, p90rsk, pp90rsk, 90kDa
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 20112
VEGA: 17
Homologene: 100680
Carmil1
Name: capping protein regulator and myosin 1 linker 1
Synonyms: Lrrc16, 1110037D04Rik, Carmil, Lrrc16a
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 68732
Homologene: 9757
Mrps27
Name: mitochondrial ribosomal protein S27
Synonyms: 2610028H14Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218506
VEGA: 13
Homologene: 41006
9630014M24Rik
Name: RIKEN cDNA 9630014M24 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Ralgapb
Name: Ral GTPase activating protein, beta subunit (non-catalytic)
Synonyms: B230339M05Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228850
Homologene: 10666
Rbbp5
Name: retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
Synonyms: 4933411J24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 213464
HGNC: HGNC:9888
Homologene: 3709
Cep170
Name: centrosomal protein 170
Synonyms: 4933426L22Rik, A330004A13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 545389
Homologene: 22844
Smc4
Name: structural maintenance of chromosomes 4
Synonyms: Smc4l1, 2500002A22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70099
Homologene: 4015
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: Bolvr, mBLVR1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Lin54
Name: lin-54 DREAM MuvB core complex component
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231506
Homologene: 18212
Sars1
Name: seryl-tRNA synthetase 1
Synonyms: Sars, Strs
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20226
Homologene: 4751
Nodal
Name: nodal growth differentiation factor
Synonyms: Tg.413d
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 18119
HGNC: HGNC:7865
Homologene: 8417
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Rcor1
Name: REST corepressor 1
Synonyms: 6720480E22Rik, D12Wsu95e, Rocr1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217864
Homologene: 32246
Casz1
Name: castor zinc finger 1
Synonyms: D4Ertd432e, 2410019P08Rik, Cst, castor
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69743
Homologene: 9824
Fbxl5
Name: F-box and leucine-rich repeat protein 5
Synonyms: Fbl4, Fir4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 242960
Homologene: 8129
Ptgfrn
Name: prostaglandin F2 receptor negative regulator
Synonyms: CD9P-1, 4833445A08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19221
HGNC: HGNC:9601
Homologene: 7908
C1qtnf1
Name: C1q and tumor necrosis factor related protein 1
Synonyms: CTRP1, 1600017K21Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56745
Homologene: 10548
Sec31a
Name: SEC31 homolog A, COPII coat complex component
Synonyms: Sec31l1, 1810024J13Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69162
Homologene: 42056
Selenof
Name: selenoprotein F
Synonyms: Sep15
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 93684
Homologene: 3145
Dync2i1
Name: dynein 2 intermediate chain 1
Synonyms: Wdr60, D430033N04Rik, Dync2l1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217935
VEGA: 12
Homologene: 23067
Caprin2
Name: caprin family member 2
Synonyms: RNG140, C1qdc1, Eeg1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232560
Homologene: 11393
Rlbp1
Name: retinaldehyde binding protein 1
Synonyms: 3110056M11Rik, CRALBP
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19771
Homologene: 68046
Prkcb
Name: protein kinase C, beta
Synonyms: Prkcb2, PKC-Beta, A130082F03Rik, Prkcb1, Pkcb
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18751
HGNC: HGNC:9395
Homologene: 56424
Anpep
Name: alanyl aminopeptidase, membrane
Synonyms: Apn, aminopeptidase N, Cd13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Ttll5
Name: tubulin tyrosine ligase-like family, member 5
Synonyms: STAMP, 4930556H18Rik, 2310009M18Rik, 1700048H13Rik, D630041K24Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320244
Homologene: 9013
Mroh7
Name: maestro heat-like repeat family member 7
Synonyms: Gm1027, Heatr8, LOC381538
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381538
Homologene: 19633
Fig4
Name: FIG4 phosphoinositide 5-phosphatase
Synonyms: A530089I17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103199
VEGA: 10
Homologene: 6713
Tnr
Name: tenascin R
Synonyms: TN-R, J1-tenascin, restrictin, janusin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21960
Homologene: 124416
Kctd19
Name: potassium channel tetramerisation domain containing 19
Synonyms: 4922504H04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 279499
Homologene: 18630
Tcea2
Name: transcription elongation factor A (SII), 2
Synonyms: S-II-T1, Tceat, SII-T1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21400
Homologene: 68304
Ints10
Name: integrator complex subunit 10
Synonyms: 4921521J11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 70885
Homologene: 10029
Agl
Name: amylo-1,6-glucosidase, 4-alpha-glucanotransferase
Synonyms: 9630046L06Rik, 9430004C13Rik, 1110061O17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77559
HGNC: HGNC:321
Homologene: 536
Ptpro
Name: protein tyrosine phosphatase receptor type O
Synonyms: D28, PTPROt, Ptpn15, PTP-oc, GLEPP1, PTP-U2, PTP-BK, PTP-phi
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 19277
HGNC: HGNC:9678
Homologene: 21564
Dclk1
Name: doublecortin-like kinase 1
Synonyms: Click-I, 1700113D08Rik, Dcl, DCLK, CPG16, Dcamkl1, 2810480F11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13175
HGNC: HGNC:2700
Homologene: 130530
Nlrp9b
Name: NLR family, pyrin domain containing 9B
Synonyms: Nalp9b, Nalp-delta
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243874
Homologene: 18530
Ccdc110
Name: coiled-coil domain containing 110
Synonyms: LOC212392
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 212392
Homologene: 17668
Psme2b
Name: protease (prosome, macropain) activator subunit 2B
Synonyms: Psme2b, Psme2-like, PA28b2, Psme2b-ps
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 621823
HGNC: HGNC:9569
AC138665.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
P2ry14
Name: purinergic receptor P2Y, G-protein coupled, 14
Synonyms: A330108O13Rik, Gpr105, P2Y14
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 140795
Homologene: 15769
Nod1
Name: nucleotide-binding oligomerization domain containing 1
Synonyms: Card4, Nlrc1, F830007N14Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 107607
Homologene: 4440
Atp6v0a2
Name: ATPase, H+ transporting, lysosomal V0 subunit A2
Synonyms: Tj6, TJ6s, ATP6a2, Atp6n2, 8430408C20Rik, V-ATPase a2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 21871
Homologene: 56523
Ctcfl
Name: CCCTC-binding factor like
Synonyms: OTTMUSG00000016680, Boris
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 664799
Homologene: 46476
Kif21b
Name: kinesin family member 21B
Synonyms: N-5 kinesin, 2610511N21Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 16565
Homologene: 56868
Or13c25
Name: olfactory receptor family 13 subfamily C member 25
Synonyms: Olfr272, GA_x6K02T2N78B-7084885-7085844, MOR262-7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 258836
Homologene: 17409
Lrrc8e
Name: leucine rich repeat containing 8 family, member E
Synonyms: 1810049O03Rik, C87354
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 72267
Homologene: 11817
Zfp395
Name: zinc finger protein 395
Synonyms: BC027382, LOC380912
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 380912
VEGA: 14
Homologene: 10255
Cdadc1
Name: cytidine and dCMP deaminase domain containing 1
Synonyms: NYD-SP15, 2310010M10Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 71891
VEGA: 14
Homologene: 12794
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Zfp438
Name: zinc finger protein 438
Synonyms: 9430091M14Rik, B830013J05Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240186
VEGA: 18
Homologene: 18695
Hsp90b1
Name: heat shock protein 90, beta (Grp94), member 1
Synonyms: tumor rejection antigen (gp96) 1, Tra1, 90 kDa, GRP94, Targ2, ERp99, Tra-1, endoplasmin, gp96
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22027
Homologene: 2476
Efcab3
Name: EF-hand calcium binding domain 3
Synonyms: Gm11639, Efcab15, 4921510J17Rik, Gm11639, Efcab13
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 108167860
Homologene: 18304
Ccdc102a
Name: coiled-coil domain containing 102A
Synonyms: LOC234582
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234582
Homologene: 13240
Serpinb7
Name: serine (or cysteine) peptidase inhibitor, clade B, member 7
Synonyms: ovalbumin, 4631416M05Rik, megsin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116872
Homologene: 68363
Pcdh1
Name: protocadherin 1
Synonyms: 2010005A06Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 75599
HGNC: HGNC:8655
Homologene: 12613
Catsperb
Name: cation channel sperm associated auxiliary subunit beta
Synonyms: 4932415G16Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 271036
VEGA: 12
Homologene: 81904
Col4a6
Name: collagen, type IV, alpha 6
Type: Gene
Species: Mouse
Chromosome: X
NCBI: 94216
HGNC: HGNC:2208
Homologene: 48050
Ighe
Name: Immunoglobulin heavy constant epsilon
Synonyms: Gm900, LOC380792
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380792
HGNC: HGNC:5522
Or9e1
Name: olfactory receptor family 9 subfamily E member 1
Synonyms: MOR222-1, Olfr311, GA_x6K02T2NKPP-565870-564944
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258530
Homologene: 77375
Snrpa1
Name: small nuclear ribonucleoprotein polypeptide A'
Synonyms: U2 snRNP-A', 1500015N06Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 68981
Homologene: 2325
Vps45
Name: vacuolar protein sorting 45
Synonyms: mVps45
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22365
Homologene: 5250
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13119
Homologene: 134697
Ccdc90b
Name: coiled-coil domain containing 90B
Synonyms: 2310015N07Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 66365
Homologene: 23328
Evi2b
Name: ecotropic viral integration site 2b
Synonyms: Evi2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216984
HGNC: HGNC:3500
Homologene: 48438
Asb16
Name: ankyrin repeat and SOCS box-containing 16
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217217
Homologene: 76813
Or2b2b
Name: olfactory receptor family 2 subfamily B member 2B
Synonyms: MOR256-10, MOR256-35, GA_x6K02T2QHY8-11561962-11562903, Olfr1360
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 258536
Homologene: 11056
Nhlrc1
Name: NHL repeat containing 1
Synonyms: B230309E09Rik, EPM2B, Malin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 105193
VEGA: 13
Homologene: 18439
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 107,428,268 bp
  • C to T, chromosome 1 at 132,494,282 bp
  • C to T, chromosome 1 at 136,169,178 bp
  • T to A, chromosome 1 at 159,850,105 bp
  • C to A, chromosome 1 at 176,739,932 bp
  • G to A, chromosome 2 at 30,084,691 bp
  • T to C, chromosome 2 at 158,465,826 bp
  • C to T, chromosome 2 at 173,112,348 bp
  • A to G, chromosome 2 at 180,180,151 bp
  • T to C, chromosome 2 at 180,542,647 bp
  • A to G, chromosome 2 at 181,686,958 bp
  • T to C, chromosome 3 at 55,477,823 bp
  • T to A, chromosome 3 at 59,115,265 bp
  • T to C, chromosome 3 at 59,618,652 bp
  • T to A, chromosome 3 at 69,016,772 bp
  • C to T, chromosome 3 at 96,048,346 bp
  • A to G, chromosome 3 at 101,060,654 bp
  • T to A, chromosome 3 at 107,445,427 bp
  • A to T, chromosome 3 at 108,433,145 bp
  • A to G, chromosome 3 at 116,780,735 bp
  • A to T, chromosome 3 at 144,594,924 bp
  • T to C, chromosome 4 at 52,910,996 bp
  • A to G, chromosome 4 at 106,703,076 bp
  • A to G, chromosome 4 at 115,493,714 bp
  • A to G, chromosome 4 at 136,143,939 bp
  • T to A, chromosome 4 at 148,942,900 bp
  • A to T, chromosome 5 at 43,758,636 bp
  • G to C, chromosome 5 at 100,375,319 bp
  • A to T, chromosome 5 at 100,480,250 bp
  • C to A, chromosome 5 at 124,646,698 bp
  • T to C, chromosome 6 at 54,943,975 bp
  • T to A, chromosome 6 at 137,443,594 bp
  • T to A, chromosome 6 at 148,876,471 bp
  • T to A, chromosome 7 at 20,048,847 bp
  • T to A, chromosome 7 at 66,070,661 bp
  • C to T, chromosome 7 at 79,380,060 bp
  • C to T, chromosome 7 at 79,838,256 bp
  • C to T, chromosome 7 at 92,581,816 bp
  • C to T, chromosome 7 at 122,627,693 bp
  • A to G, chromosome 8 at 4,234,990 bp
  • G to T, chromosome 8 at 45,942,325 bp
  • A to G, chromosome 8 at 68,796,713 bp
  • A to G, chromosome 8 at 70,485,154 bp
  • A to T, chromosome 8 at 94,907,713 bp
  • A to G, chromosome 8 at 105,387,879 bp
  • A to T, chromosome 10 at 41,188,586 bp
  • T to C, chromosome 10 at 61,422,985 bp
  • A to T, chromosome 10 at 80,715,941 bp
  • A to G, chromosome 10 at 86,694,042 bp
  • T to A, chromosome 11 at 48,945,382 bp
  • T to A, chromosome 11 at 58,841,651 bp
  • T to C, chromosome 11 at 79,515,586 bp
  • T to A, chromosome 11 at 94,457,039 bp
  • A to G, chromosome 11 at 102,272,576 bp
  • T to C, chromosome 11 at 105,108,900 bp
  • C to T, chromosome 11 at 118,447,923 bp
  • C to T, chromosome 12 at 85,892,208 bp
  • G to A, chromosome 12 at 101,412,330 bp
  • T to A, chromosome 12 at 111,103,603 bp
  • T to A, chromosome 12 at 113,271,446 bp
  • G to T, chromosome 12 at 116,241,790 bp
  • T to A, chromosome 13 at 13,635,101 bp
  • T to A, chromosome 13 at 21,674,530 bp
  • T to C, chromosome 13 at 24,099,054 bp
  • C to T, chromosome 13 at 47,014,344 bp
  • T to A, chromosome 13 at 99,405,050 bp
  • T to G, chromosome 14 at 27,099,958 bp
  • G to A, chromosome 14 at 31,011,592 bp
  • G to T, chromosome 14 at 59,586,083 bp
  • T to A, chromosome 14 at 59,586,092 bp
  • T to C, chromosome 14 at 65,393,074 bp
  • A to G, chromosome 17 at 7,292,906 bp
  • A to G, chromosome 18 at 5,210,740 bp
  • T to C, chromosome 18 at 38,189,726 bp
  • T to G, chromosome 18 at 38,601,687 bp
  • T to C, chromosome X at 141,227,858 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1540 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039579-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.