Strain Name:
C57BL/6J-MtgxR1732Btlr/Mmmh
Stock Number:
039764-MU
Citation ID:
RRID:MMRRC_039764-MU
Other Names:
R1732 (G1), C57BL/6J-MtgxR1732Btlr
Major Collection:

Strain Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Col1a-1, Cola-1, Mov-13, Cola1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Avpr1b
Name: arginine vasopressin receptor 1B
Synonyms: V1bR, V3/V1b pituitary vasopressin receptor, V3/V1b, V1BR, AVPR3, VPR3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 26361
HGNC: HGNC:896
Homologene: 22678
Atp1a1
Name: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Synonyms: Atpa-1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11928
HGNC: HGNC:799
Homologene: 564
Ctbp2
Name: C-terminal binding protein 2
Synonyms: D7Ertd45e, Gtrgeo6, Ribeye
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13017
HGNC: HGNC:2495
Homologene: 75187
Actn4
Name: actinin alpha 4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 60595
HGNC: HGNC:166
Homologene: 55857
Tpgs1
Name: tubulin polyglutamylase complex subunit 1
Synonyms: Gm16517, Gtrgeo22
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110012
VEGA: 10
Homologene: 17525
Rabep1
Name: rabaptin, RAB GTPase binding effector protein 1
Synonyms: RAB5 effector protein, neurocrescin, rabaptin-5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 54189
Homologene: 3451
Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Synonyms: Rsk1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 20111
Homologene: 55703
Smarcc1
Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
Synonyms: SRG3, BAF155, msp3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20588
Homologene: 68296
Psme4
Name: proteasome (prosome, macropain) activator subunit 4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103554
Homologene: 113742
Triobp
Name: TRIO and F-actin binding protein
Synonyms: Tara, Mus EST 478828, EST478828
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110253
Homologene: 5104
Agpat4
Name: 1-acylglycerol-3-phosphate O-acyltransferase 4
Synonyms: 1500003P24Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 68262
Homologene: 69293
Prr12
Name: proline rich 12
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233210
Homologene: 18957
Hdac4
Name: histone deacetylase 4
Synonyms: 4932408F19Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 208727
Homologene: 55946
Cpne1
Name: copine I
Synonyms: 1810028N16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 266692
HGNC: HGNC:2314
Homologene: 36501
Nudcd3
Name: NudC domain containing 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 209586
Homologene: 9097
Dmxl1
Name: Dmx-like 1
Synonyms: C630007L23Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240283
HGNC: HGNC:2937
Homologene: 21136
Rps6ka5
Name: ribosomal protein S6 kinase, polypeptide 5
Synonyms: MSK1, 6330404E13Rik, 3110005L17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73086
VEGA: 12
Homologene: 48302
Chek2
Name: checkpoint kinase 2
Synonyms: Rad53, CHK2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50883
Homologene: 38289
Otof
Name: otoferlin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 83762
HGNC: HGNC:8515
Homologene: 12892
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: Gpr1g, E130018M02Rik, mGluR7, mGlu7a receptor, 6330570A01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Peg3
Name: paternally expressed 3
Synonyms: Gcap4, End4, Pw1, Zfp102
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18616
HGNC: HGNC:8826
Homologene: 31363
Bmp1
Name: bone morphogenetic protein 1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 12153
VEGA: 14
HGNC: HGNC:1067
Homologene: 55955
Ube3b
Name: ubiquitin protein ligase E3B
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 117146
Homologene: 13775
Impdh2
Name: inosine monophosphate dehydrogenase 2
Synonyms: IMP dehydrogenase type II
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 23918
HGNC: HGNC:6053
Homologene: 48919
Prim1
Name: DNA primase, p49 subunit
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 19075
HGNC: HGNC:9369
Homologene: 730
Tenm3
Name: teneurin transmembrane protein 3
Synonyms: 2610100B16Rik, Odz3, Ten-m3
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23965
Homologene: 22673
Fam135a
Name: family with sequence similarity 135, member A
Synonyms: 4921533L14Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68187
Homologene: 32665
2700049A03Rik
Name: RIKEN cDNA 2700049A03 gene
Synonyms: Ta3, talpid3
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76967
Homologene: 8839
Rbm14
Name: RNA binding motif protein 14
Synonyms: p16, PSP2, 1300007E16Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56275
Homologene: 4614
Gak
Name: cyclin G associated kinase
Synonyms: D130045N16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231580
HGNC: HGNC:4113
Homologene: 3846
Fam13b
Name: family with sequence similarity 13, member B
Synonyms: 2610024E20Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225358
VEGA: 18
HGNC: HGNC:1335
Homologene: 9585
Ank1
Name: ankyrin 1, erythroid
Synonyms: pale, Ank-1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 11733
HGNC: HGNC:492
Homologene: 55427
F10
Name: coagulation factor X
Synonyms: AI194738, fX, Cf10
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14058
HGNC: HGNC:3528
Homologene: 30976
Slc9c1
Name: solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
Synonyms: LOC208169, spermNHE, Slc9a10
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208169
Homologene: 19505
Acacb
Name: acetyl-Coenzyme A carboxylase beta
Synonyms: Accb, Acc2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100705
HGNC: HGNC:85
Homologene: 74382
F5
Name: coagulation factor V
Synonyms: Cf-5, Cf5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 14067
HGNC: HGNC:3542
Homologene: 104
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: b2b585Clo, PC6, SPC6, PC5/6A, PC5A, b2b1549Clo
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Fyco1
Name: FYVE and coiled-coil domain containing 1
Synonyms: ZFYVE7, Mem2, 2810409M01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 17281
Homologene: 11561
Ptpdc1
Name: protein tyrosine phosphatase domain containing 1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218232
VEGA: 13
Homologene: 17576
Nwd1
Name: NACHT and WD repeat domain containing 1
Synonyms: A230063L24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319555
Homologene: 72261
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Krt6a
Name: keratin 6A
Synonyms: mK6[a], Krt2-6c, Krt2-6a, MK6a
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16687
VEGA: 15
Homologene: 136794
Hcn3
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 3
Synonyms: Hac3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 15168
Homologene: 22453
Plce1
Name: phospholipase C, epsilon 1
Synonyms: PLCepsilon, 4933403A21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 74055
Homologene: 9478
Itgad
Name: integrin, alpha D
Synonyms: Cd11d
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381924
HGNC: HGNC:6146
Homologene: 56919
Cep126
Name: centrosomal protein 126
Synonyms: AK129341
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234915
VEGA: 9
Homologene: 28313
Zfp607a
Name: zinc finger protein 607A
Synonyms: Zfp607, 4732475C15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 545938
Homologene: 134321
Mybpc2
Name: myosin binding protein C, fast-type
Synonyms: Fast-type C-protein
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233199
HGNC: HGNC:7550
Homologene: 3331
Cyld
Name: CYLD lysine 63 deubiquitinase
Synonyms: 2900009M21Rik, C130039D01Rik, CYLD1, 2010013M14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74256
HGNC: HGNC:2584
Homologene: 9069
Srp54a
Name: signal recognition particle 54A
Synonyms: 54kDa, 54K subunit of signal recognition particle, Srp54
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24067
VEGA: 12
Homologene: 2362
Dennd3
Name: DENN domain containing 3
Synonyms: E030003N15Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105841
Homologene: 28254
Phldb2
Name: pleckstrin homology like domain, family B, member 2
Synonyms: C820004H04Rik, LL5b, LL5beta
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 208177
Homologene: 17100
Cyp3a57
Name: cytochrome P450, family 3, subfamily a, polypeptide 57
Synonyms: EG622127
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 622127
Homologene: 135775
Noa1
Name: nitric oxide associated 1
Synonyms: 2610024G14Rik, mAtNOS1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 56412
Homologene: 10518
Tmem106c
Name: transmembrane protein 106C
Synonyms: D15Ertd405e
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 380967
VEGA: 15
Homologene: 11440
Synj1
Name: synaptojanin 1
Synonyms: A930006D20Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 104015
Homologene: 48252
Slc34a1
Name: solute carrier family 34 (sodium phosphate), member 1
Synonyms: Na/Pi cotransporter, Slc17a2, Npt2, NaPi-IIa, renal Na+/Pi transporter
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20505
VEGA: 13
Homologene: 20663
Adam7
Name: a disintegrin and metallopeptidase domain 7
Synonyms: EAP1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 11500
HGNC: HGNC:214
Homologene: 2830
Acap3
Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
Synonyms: Centb5, Kiaa1716-hp
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 140500
Homologene: 23708
Slc28a2
Name: solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
Synonyms: 2010208B10Rik, CNT2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 269346
Homologene: 20891
Kcnb2
Name: potassium voltage gated channel, Shab-related subfamily, member 2
Synonyms: 9630047L19Rik, Kv2.2
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 98741
HGNC: HGNC:6232
Homologene: 31263
Cntnap3
Name: contactin associated protein-like 3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 238680
VEGA: 13
Homologene: 129602
Tspan2
Name: tetraspanin 2
Synonyms: B230119D02Rik, 6330415F13Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70747
Homologene: 21169
AC091683.1
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Cmbl
Name: carboxymethylenebutenolidase homolog
Synonyms: 2310016A09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69574
Homologene: 100714
Rec114
Name: REC114 meiotic recombination protein
Synonyms: 4930527A11Rik, 2410076I21Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 73673
Homologene: 83546
Tmem151a
Name: transmembrane protein 151A
Synonyms: Tmem151, LOC381199, Gm30627
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 381199
Homologene: 17721
Gm9982
Name: predicted gene 9982
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Or7e174
Name: olfactory receptor family 7 subfamily E member 174
Synonyms: Olfr868, MOR145-4, GA_x6K02T2PVTD-13841888-13842802
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258552
HGNC: HGNC:8396
Homologene: 74168
Actl9
Name: actin-like 9
Synonyms: 1700029I08Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 69481
Homologene: 77642
Klhl22
Name: kelch-like 22
Synonyms: Kelchl, 2610318I18Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224023
Homologene: 23784
Phtf2
Name: putative homeodomain transcription factor 2
Synonyms: 1110054G21Rik, 9530062N20Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 68770
Homologene: 10713
Tgm2
Name: transglutaminase 2, C polypeptide
Synonyms: protein-glutamine gamma-glutamyltransferase, TGase2, TG2, tissue transglutaminase, tTGas, tTG, TG C, G[a]h
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 21817
Homologene: 3391
Ephb4
Name: Eph receptor B4
Synonyms: Tyro11, b2b2412Clo, MDK2, Htk, Myk1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 13846
HGNC: HGNC:3395
Homologene: 20939
Vmn1r32
Name: vomeronasal 1 receptor 32
Synonyms: V1rc15
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 171188
Homologene: 115644
Lonrf2
Name: LON peptidase N-terminal domain and ring finger 2
Synonyms: 2900060P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381338
Homologene: 18871
Cwc15
Name: CWC15 spliceosome-associated protein
Synonyms: 2900052N06Rik, 0610040D20Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 66070
Homologene: 9499
Slc7a9
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
Synonyms: CSNU3, bo, + amino acid transporter, bo, +AT
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 30962
Homologene: 56668
Top1mt
Name: DNA topoisomerase 1, mitochondrial
Synonyms: 2900052H09Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 72960
Homologene: 43082
Stambpl1
Name: STAM binding protein like 1
Synonyms: 8230401J17Rik, 1700095N21Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 76630
Homologene: 23253
Gpr25
Name: G protein-coupled receptor 25
Synonyms: LOC383563
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 383563
HGNC: HGNC:4480
Homologene: 3872
Or55b10
Name: olfactory receptor family 55 subfamily B member 10
Synonyms: GA_x6K02T2PBJ9-5216160-5215210, S50, Olfr545, MOR42-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258837
Homologene: 17410
Krtap10-26
Name: keratin associated protein 10-26
Synonyms: Gm7138
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102640500
VEGA: 10
Homologene: 115744
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 15,709,755 bp
  • A to T, chromosome 1 at 24,026,653 bp
  • G to A, chromosome 1 at 38,813,276 bp
  • T to A, chromosome 1 at 91,947,535 bp
  • T to C, chromosome 1 at 131,600,254 bp
  • A to G, chromosome 1 at 136,260,128 bp
  • G to A, chromosome 1 at 164,174,150 bp
  • A to C, chromosome 1 at 178,256,651 bp
  • T to C, chromosome 2 at 122,449,758 bp
  • C to A, chromosome 2 at 156,074,176 bp
  • T to C, chromosome 2 at 158,134,357 bp
  • T to C, chromosome 3 at 89,148,119 bp
  • C to A, chromosome 3 at 101,584,799 bp
  • A to G, chromosome 3 at 102,768,877 bp
  • A to T, chromosome 4 at 133,860,070 bp
  • T to C, chromosome 4 at 155,900,994 bp
  • A to T, chromosome 5 at 20,789,627 bp
  • A to T, chromosome 5 at 30,386,471 bp
  • A to T, chromosome 5 at 77,306,374 bp
  • A to T, chromosome 5 at 108,576,582 bp
  • G to T, chromosome 5 at 110,872,102 bp
  • A to T, chromosome 5 at 114,190,087 bp
  • A to G, chromosome 5 at 114,387,445 bp
  • A to G, chromosome 5 at 137,372,178 bp
  • A to T, chromosome 5 at 145,365,645 bp
  • A to T, chromosome 6 at 66,553,301 bp
  • T to C, chromosome 6 at 110,703,432 bp
  • T to C, chromosome 7 at 6,709,085 bp
  • G to T, chromosome 7 at 27,878,459 bp
  • G to A, chromosome 7 at 28,898,266 bp
  • T to C, chromosome 7 at 35,459,838 bp
  • C to A, chromosome 7 at 44,513,675 bp
  • T to A, chromosome 7 at 45,048,356 bp
  • C to A, chromosome 7 at 102,494,040 bp
  • T to C, chromosome 7 at 128,205,107 bp
  • T to C, chromosome 7 at 132,998,924 bp
  • T to C, chromosome 8 at 13,050,764 bp
  • T to A, chromosome 8 at 23,111,463 bp
  • T to A, chromosome 8 at 48,310,634 bp
  • C to G, chromosome 8 at 72,666,835 bp
  • C to T, chromosome 8 at 88,731,667 bp
  • A to T, chromosome 9 at 8,099,761 bp
  • A to G, chromosome 9 at 14,510,247 bp
  • A to G, chromosome 9 at 20,101,500 bp
  • A to G, chromosome 9 at 58,653,106 bp
  • C to T, chromosome 9 at 108,562,389 bp
  • T to A, chromosome 9 at 110,185,820 bp
  • T to C, chromosome 9 at 123,819,092 bp
  • A to T, chromosome 10 at 77,776,848 bp
  • T to A, chromosome 10 at 79,675,594 bp
  • T to C, chromosome 10 at 128,015,324 bp
  • A to G, chromosome 11 at 6,113,440 bp
  • G to A, chromosome 11 at 30,848,105 bp
  • A to G, chromosome 11 at 70,904,641 bp
  • A to T, chromosome 11 at 94,944,415 bp
  • G to T, chromosome 11 at 115,988,918 bp
  • T to A, chromosome 12 at 55,252,759 bp
  • C to A, chromosome 12 at 71,219,221 bp
  • A to C, chromosome 12 at 100,678,505 bp
  • T to C, chromosome 13 at 48,586,545 bp
  • T to A, chromosome 13 at 49,901,926 bp
  • A to G, chromosome 13 at 55,413,420 bp
  • A to T, chromosome 13 at 64,740,812 bp
  • T to C, chromosome 14 at 68,498,450 bp
  • A to T, chromosome 14 at 70,486,265 bp
  • A to T, chromosome 15 at 31,588,232 bp
  • T to A, chromosome 15 at 73,537,418 bp
  • A to G, chromosome 15 at 75,666,251 bp
  • T to A, chromosome 15 at 78,967,228 bp
  • C to A, chromosome 15 at 97,967,107 bp
  • C to T, chromosome 15 at 101,693,731 bp
  • T to A, chromosome 16 at 17,777,024 bp
  • A to G, chromosome 16 at 45,552,928 bp
  • T to C, chromosome 16 at 45,757,166 bp
  • T to C, chromosome 16 at 90,964,230 bp
  • T to C, chromosome 17 at 12,216,728 bp
  • T to C, chromosome 17 at 33,433,122 bp
  • A to T, chromosome 18 at 34,487,134 bp
  • T to A, chromosome 18 at 49,893,444 bp
  • T to A, chromosome 18 at 49,902,988 bp
  • A to G, chromosome 19 at 4,803,467 bp
  • C to A, chromosome 19 at 5,082,867 bp
  • T to C, chromosome 19 at 17,568,255 bp
  • C to G, chromosome 19 at 34,226,721 bp
  • G to T, chromosome 19 at 38,716,838 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1732 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039764-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.