Strain Name:
C57BL/6J-MtgxR1816Btlr/Mmmh
Stock Number:
039844-MU
Citation ID:
RRID:MMRRC_039844-MU
Other Names:
R1816 (G1), C57BL/6J-MtgxR1816Btlr
Major Collection:

Strain Information

Myo10
Name: myosin X
Synonyms: D15Ertd600e, myosin-X
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 17909
HGNC: HGNC:7593
Homologene: 36328
Stx8
Name: syntaxin 8
Synonyms: 0610007H08Rik, 4930571E13Rik, 1110002H11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 55943
Homologene: 37973
Dicer1
Name: dicer 1, ribonuclease type III
Synonyms: 1110006F08Rik, D12Ertd7e, Dicer1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 192119
VEGA: 12
Homologene: 13251
Camkk2
Name: calcium/calmodulin-dependent protein kinase kinase 2, beta
Synonyms: 6330570N16Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 207565
HGNC: HGNC:1470
Homologene: 32756
Itga6
Name: integrin alpha 6
Synonyms: 5033401O05Rik, Cd49f
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16403
HGNC: HGNC:6142
Homologene: 20091
Tfap2b
Name: transcription factor AP-2 beta
Synonyms: AP-2(beta), E130018K07Rik, Tcfap2b
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 21419
Homologene: 20688
Tnpo3
Name: transportin 3
Synonyms: D6Ertd313e, 5730544L10Rik, C430013M08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 320938
Homologene: 40848
Ulk1
Name: unc-51 like kinase 1
Synonyms: Unc51.1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 22241
Homologene: 2640
Pcm1
Name: pericentriolar material 1
Synonyms: C030044G17Rik, 9430077F19Rik, 2600002H09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18536
HGNC: HGNC:8727
Homologene: 4518
Anks1
Name: ankyrin repeat and SAM domain containing 1
Synonyms: Odin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224650
Homologene: 9068
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, C030018K18Rik, Pdzgef2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Ankib1
Name: ankyrin repeat and IBR domain containing 1
Synonyms: 2310061P20Rik, 4631416I11Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 70797
Homologene: 19076
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki67, Ki-67, D630048A14Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Tlr2
Name: toll-like receptor 2
Synonyms: Ly105
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 24088
Homologene: 20695
Klf4
Name: Kruppel-like transcription factor 4 (gut)
Synonyms: EZF, Gklf, Zie
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16600
HGNC: HGNC:6348
Homologene: 3123
Efna1
Name: ephrin A1
Synonyms: Lerk1, Eplg1, EFL-1, Epl1, LERK-1, B61
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 13636
HGNC: HGNC:3221
Homologene: 3262
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, LOC381341, Dnahc7a
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 627872
Homologene: 41287
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: Gpr1g, E130018M02Rik, mGluR7, mGlu7a receptor, 6330570A01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, 9330188B09Rik, D630001M17Rik, 4921513O20Rik, LOC381026
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Rfx2
Name: regulatory factor X, 2 (influences HLA class II expression)
Synonyms: 5430432H19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19725
VEGA: 17
HGNC: HGNC:9983
Homologene: 30980
Zdhhc20
Name: zinc finger, DHHC domain containing 20
Synonyms: 4930542A17Rik, B230110O18Rik, 5033406L14Rik, ENSMUSG00000055956
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75965
VEGA: 14
Homologene: 57105
Pi4k2b
Name: phosphatidylinositol 4-kinase type 2 beta
Synonyms: 4933409G22Rik, 2610042N09Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 67073
Homologene: 32405
Ube2s
Name: ubiquitin-conjugating enzyme E2S
Synonyms: 6720465F12Rik, E2-EPF, 0910001J09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 77891
Homologene: 56676
Htt
Name: huntingtin
Synonyms: HD, IT15, C430023I11Rik, htt, Hdh, huntingtin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15194
HGNC: HGNC:4851
Homologene: 1593
Nrbp1
Name: nuclear receptor binding protein 1
Synonyms: Nrbp, B230344L17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 192292
HGNC: HGNC:7993
Homologene: 8373
Zfp958
Name: zinc finger protein 958
Synonyms: BC003267
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 233987
Homologene: 129582
Pgap1
Name: post-GPI attachment to proteins 1
Synonyms: PGAP1, 5033403E17Rik, D230012E17Rik, 9030223K07Rik, oto
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 241062
Homologene: 41605
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 12870
HGNC: HGNC:2295
Homologene: 75
Trappc14
Name: trafficking protein particle complex 14
Synonyms: BC037034, Map11
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231807
Homologene: 10106
Pkhd1l1
Name: polycystic kidney and hepatic disease 1-like 1
Synonyms: D86 mRNA, PKHDL1, fibrocystin L
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 192190
Homologene: 16332
Slc4a1
Name: solute carrier family 4 (anion exchanger), member 1
Synonyms: erythrocyte membrane protein band 3, Empb3, Ae1, CD233, l11Jus51, band 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20533
Homologene: 133556
Eaf2
Name: ELL associated factor 2
Synonyms: Traits, FESTA-L, Festa, FESTA-S, U19
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 106389
Homologene: 10208
Fer1l4
Name: fer-1 like family member 4
Synonyms: 9130402C12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 74562
Homologene: 19075
Ceacam12
Name: CEA cell adhesion molecule 12
Synonyms: 1600031J20Rik, Ceacam12-C1, Ceacam12-C3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67315
Homologene: 137375
Ac127374.1
Name: Uncharacterized protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Or8k33
Name: olfactory receptor family 8 subfamily K member 33
Synonyms: MOR192-1, Olfr1080, GA_x6K02T2Q125-48039418-48038477
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258404
Homologene: 104285
Or5p80
Name: olfactory receptor family 5 subfamily P member 80
Synonyms: GA_x6K02T2PBJ9-10959726-10960658, Olfr508, MOR204-6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258769
Homologene: 72039
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: 4930572H05Rik, Arhgap13
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 117600
Homologene: 56898
Stab1
Name: stabilin 1
Synonyms: MS-1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 192187
Homologene: 9035
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Or5g29
Name: olfactory receptor family 5 subfamily G member 29
Synonyms: MOR175-5, Olfr998, GA_x6K02T2Q125-47069356-47070300
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258428
Homologene: 74236
4933405L10Rik
Name: RIKEN cDNA 4933405L10 gene
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 71046
Homologene: 19274
Pitpnm3
Name: PITPNM family member 3
Synonyms: Ackr6, A330068P14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 327958
Homologene: 66271
Dhx58
Name: DExH-box helicase 58
Synonyms: D11Lgp2e, B430001I08Rik, LPG2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 80861
Homologene: 69371
Gm973
Name: predicted gene 973
Synonyms: LOC381260
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381260
Homologene: 124277
Bfsp1
Name: beaded filament structural protein 1, in lens-CP94
Synonyms: filensin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12075
HGNC: HGNC:1040
Homologene: 922
Nudt12
Name: nudix hydrolase 12
Synonyms: nudix (nucleoside diphosphate linked moiety X)-type motif 12, 0610016O18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 67993
Homologene: 44188
Vmn2r27
Name: vomeronasal 2, receptor27
Synonyms: EG232367
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232367
Or4p18
Name: olfactory receptor family 4 subfamily P member 18
Synonyms: Olfr1179, MOR225-2, GA_x6K02T2Q125-49890854-49889931
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258919
Homologene: 74070
Vmn2r92
Name: vomeronasal 2, receptor 92
Synonyms: EG627111
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 627111
Homologene: 115024
Tmem268
Name: transmembrane protein 268
Synonyms: 6330416G13Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230279
Homologene: 17005
Hbb-bh2
Name: hemoglobin beta, bh2
Synonyms: Gm5736
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 436003
Cfh
Name: complement component factor h
Synonyms: Mud-1, Sas-1, Sas1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12628
HGNC: HGNC:4883
Homologene: 20086
Fam83d
Name: family with sequence similarity 83, member D
Synonyms: 2310007D09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71878
Homologene: 23715
Gm14226
Name: predicted gene 14226
Type: Gene
Species: Mouse
Chromosome: 2
Etnppl
Name: ethanolamine phosphate phospholyase
Synonyms: Agxt2l1, 1300019H02Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71760
Homologene: 69440
Sh3tc1
Name: SH3 domain and tetratricopeptide repeats 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231147
Homologene: 10360
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 636808
Homologene: 43974
Thoc2l
Name: THO complex subunit 2-like
Synonyms: BC005561, Gm3179
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100042165
Or1e33
Name: olfactory receptor family 1 subfamily E member 33
Synonyms: MOR135-7, Olfr393, GA_x6K02T2P1NL-4004140-4003208
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259010
Homologene: 79335
Fstl1
Name: follistatin-like 1
Synonyms: TSC-36
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 14314
HGNC: HGNC:3972
Homologene: 5144
Spata1
Name: spermatogenesis associated 1
Synonyms: SP-2, 4921536I21Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70951
Homologene: 23356
Pik3c2b
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Synonyms: PI3K-C2beta, C330011J12Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 240752
HGNC: HGNC:8972
Homologene: 20582
Or2ag1
Name: olfactory receptor family 2 subfamily AG member 1
Synonyms: MOR283-2, GA_x6K02T2PBJ9-9256348-9255398, Olfr705
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259034
Homologene: 128075
4930433I11Rik
Name: RIKEN cDNA 4930433I11 gene
Synonyms: LOC243944
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243944
Homologene: 77912
Cd84
Name: CD84 antigen
Synonyms: SLAMF5, CDw84, A130013D22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12523
HGNC: HGNC:1704
Homologene: 48249
Vmn1r49
Name: vomeronasal 1, receptor 49
Synonyms: V1r5, VRi2, V1rb2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 24112
Homologene: 113975
Tbx20
Name: T-box 20
Synonyms: Tbx12, 9430010M06Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 57246
VEGA: 9
Homologene: 32476
Snrnp25
Name: small nuclear ribonucleoprotein 25 (U11/U12)
Synonyms: 3300001G02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78372
Homologene: 11592
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68897
Homologene: 14133
Slc22a12
Name: solute carrier family 22 (organic anion/cation transporter), member 12
Synonyms: Rst, URAT1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 20521
Homologene: 56442
Adam1b
Name: a disintegrin and metallopeptidase domain 1b
Synonyms: PH-30 alpha, Ftna, fertilin alpha
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 280667
Homologene: 136485
4933434E20Rik
Name: RIKEN cDNA 4933434E20 gene
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99650
Homologene: 41041
Odam
Name: odontogenic, ameloblast asssociated
Synonyms: 2310011G06Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69592
Homologene: 49511
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 19,209,212 bp
  • A to G, chromosome 1 at 53,631,742 bp
  • A to G, chromosome 1 at 54,492,057 bp
  • A to G, chromosome 1 at 59,582,399 bp
  • G to T, chromosome 1 at 116,428,888 bp
  • C to T, chromosome 1 at 133,101,370 bp
  • T to A, chromosome 1 at 140,147,646 bp
  • A to G, chromosome 1 at 171,872,750 bp
  • T to A, chromosome 1 at 183,098,575 bp
  • T to C, chromosome 2 at 71,840,809 bp
  • G to T, chromosome 2 at 85,590,925 bp
  • A to T, chromosome 2 at 86,553,667 bp
  • T to G, chromosome 2 at 88,402,599 bp
  • C to T, chromosome 2 at 143,841,679 bp
  • A to T, chromosome 2 at 155,025,629 bp
  • C to T, chromosome 2 at 156,035,199 bp
  • G to T, chromosome 2 at 158,768,150 bp
  • T to C, chromosome 3 at 19,968,220 bp
  • T to C, chromosome 3 at 83,838,209 bp
  • T to C, chromosome 3 at 89,276,387 bp
  • T to C, chromosome 3 at 90,053,091 bp
  • T to C, chromosome 3 at 130,634,562 bp
  • G to T, chromosome 3 at 146,481,207 bp
  • G to T, chromosome 4 at 55,530,977 bp
  • C to A, chromosome 4 at 63,565,710 bp
  • A to G, chromosome 5 at 3,734,028 bp
  • T to A, chromosome 5 at 31,245,813 bp
  • C to T, chromosome 5 at 34,803,740 bp
  • C to A, chromosome 5 at 35,700,584 bp
  • T to C, chromosome 5 at 52,750,746 bp
  • A to G, chromosome 5 at 87,889,470 bp
  • A to G, chromosome 5 at 104,517,834 bp
  • A to G, chromosome 5 at 110,787,831 bp
  • T to G, chromosome 5 at 121,501,725 bp
  • A to G, chromosome 5 at 122,734,180 bp
  • A to G, chromosome 5 at 138,260,341 bp
  • T to C, chromosome 6 at 29,557,017 bp
  • G to T, chromosome 6 at 90,072,803 bp
  • A to T, chromosome 6 at 111,495,791 bp
  • C to A, chromosome 6 at 124,230,371 bp
  • T to C, chromosome 7 at 4,811,555 bp
  • T to A, chromosome 7 at 18,071,765 bp
  • T to A, chromosome 7 at 40,994,798 bp
  • G to A, chromosome 7 at 103,840,378 bp
  • A to T, chromosome 7 at 106,873,488 bp
  • T to C, chromosome 7 at 108,630,157 bp
  • T to C, chromosome 7 at 135,707,387 bp
  • A to T, chromosome 8 at 4,629,147 bp
  • T to A, chromosome 8 at 31,738,958 bp
  • T to A, chromosome 8 at 41,309,537 bp
  • T to A, chromosome 8 at 105,709,859 bp
  • A to G, chromosome 9 at 24,725,804 bp
  • T to C, chromosome 9 at 95,866,694 bp
  • G to A, chromosome 10 at 121,925,971 bp
  • G to A, chromosome 11 at 32,207,565 bp
  • G to A, chromosome 11 at 54,694,488 bp
  • T to A, chromosome 11 at 68,011,326 bp
  • T to C, chromosome 11 at 72,058,376 bp
  • T to C, chromosome 11 at 73,847,199 bp
  • A to G, chromosome 11 at 100,703,152 bp
  • A to G, chromosome 11 at 102,351,230 bp
  • A to T, chromosome 11 at 107,060,579 bp
  • T to C, chromosome 12 at 104,722,151 bp
  • T to C, chromosome 14 at 31,157,465 bp
  • A to T, chromosome 14 at 57,890,143 bp
  • T to C, chromosome 15 at 25,800,200 bp
  • T to C, chromosome 15 at 44,528,239 bp
  • T to C, chromosome 15 at 91,806,728 bp
  • T to G, chromosome 16 at 36,808,009 bp
  • A to G, chromosome 16 at 37,826,724 bp
  • C to A, chromosome 17 at 14,670,713 bp
  • T to A, chromosome 17 at 14,670,714 bp
  • A to G, chromosome 17 at 18,166,677 bp
  • T to A, chromosome 17 at 27,986,573 bp
  • C to A, chromosome 17 at 56,808,305 bp
  • G to A, chromosome 17 at 59,010,136 bp
  • G to A, chromosome 19 at 6,542,653 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1816 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039844-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.