Strain Name:
C57BL/6J-MtgxR4696Btlr/Mmmh
Stock Number:
041946-MU
Citation ID:
RRID:MMRRC_041946-MU
Other Names:
R4696 (G1), C57BL/6J-MtgxR4696Btlr
Major Collection:

Strain Information

Tln2
Name: talin 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 70549
VEGA: 9
Homologene: 56692
Tert
Name: telomerase reverse transcriptase
Synonyms: TR
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 21752
VEGA: 13
Homologene: 31141
Fgfr1
Name: fibroblast growth factor receptor 1
Synonyms: Flt-2, Fgfr-1, Hspy, Eask, FGFR-I, Fr1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14182
HGNC: HGNC:3688
Homologene: 69065
Ap2b1
Name: adaptor-related protein complex 2, beta 1 subunit
Synonyms: 1300012O03Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71770
HGNC: HGNC:563
Homologene: 137384
Anks1
Name: ankyrin repeat and SAM domain containing 1
Synonyms: Odin
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224650
Homologene: 9068
Kansl1
Name: KAT8 regulatory NSL complex subunit 1
Synonyms: 1700081L11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76719
Homologene: 9140
Polr2a
Name: polymerase (RNA) II (DNA directed) polypeptide A
Synonyms: 220kDa, Rpo2-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 20020
HGNC: HGNC:9187
Homologene: 721
Thada
Name: thyroid adenoma associated
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 240174
VEGA: 17
Homologene: 75175
Ddx42
Name: DEAD box helicase 42
Synonyms: B430002H05Rik, 1810047H21Rik, SF3b125, DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72047
Homologene: 49137
Trip11
Name: thyroid hormone receptor interactor 11
Synonyms: 3110031G15Rik, 2610511G22Rik, 6030460N08Rik, TRIP230, GMAP-210
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109181
Homologene: 20897
Zfp462
Name: zinc finger protein 462
Synonyms: Gt4-2, 9430078C22Rik, Zfpip
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242466
Homologene: 41430
R3hdm1
Name: R3H domain containing 1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226412
HGNC: HGNC:9757
Homologene: 9108
Tango6
Name: transport and golgi organization 6
Synonyms: Tmco7, Tango6
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 272538
Homologene: 52121
Zfp619
Name: zinc finger protein 619
Synonyms: 3000002G13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 70227
Homologene: 133818
Sprn
Name: shadow of prion protein
Synonyms: shadoo
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 212518
Homologene: 84643
Cntrob
Name: centrobin, centrosomal BRCA2 interacting protein
Synonyms: Lip8, 9830165K03Rik, Nip2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216846
Homologene: 14205
Acin1
Name: apoptotic chromatin condensation inducer 1
Synonyms: 2610510L13Rik, 2610036I19Rik, Acinus
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56215
Homologene: 22853
Ntm
Name: neurotrimin
Synonyms: 6230410L23Rik, B230210G24Rik, Hnt
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235106
Homologene: 41139
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Acaca
Name: acetyl-Coenzyme A carboxylase alpha
Synonyms: acetyl-CoA carboxylase, Acc1, LOC327983, Acac, A530025K05Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 107476
HGNC: HGNC:84
Homologene: 31015
Eya3
Name: EYA transcriptional coactivator and phosphatase 3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14050
HGNC: HGNC:3521
Homologene: 1508
Alms1
Name: ALMS1, centrosome and basal body associated
Synonyms: Alstrom syndrome 1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 236266
HGNC: HGNC:428
Homologene: 49406
Dzip3
Name: DAZ interacting protein 3, zinc finger
Synonyms: 6430549P11Rik, 2310047C04Rik, 2A-HUB
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224170
Homologene: 8771
Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
Synonyms: A930005E13Rik, LOC381562, D930005K06Rik, 1810009A16Rik, Zubr1, p600
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 69116
Homologene: 10804
Sbf1
Name: SET binding factor 1
Synonyms: 2610510A08Rik, Mtmr5, B230113C15Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 77980
Homologene: 84710
Vegfa
Name: vascular endothelial growth factor A
Synonyms: VPF, VEGF-A, VEGF120, Vegf, VEGF188, VEGF164
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 22339
Homologene: 2534
Glb1
Name: galactosidase, beta 1
Synonyms: Bgs, Bge, Bgt, Bgl, Bgl-t, Bgl-s, Bgl-e, C130097A14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 12091
VEGA: 9
HGNC: HGNC:4298
Homologene: 47922
Epn2
Name: epsin 2
Synonyms: Ibp2, 9530051D10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 13855
Homologene: 40710
Dmrt1
Name: doublesex and mab-3 related transcription factor 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 50796
HGNC: HGNC:2934
Homologene: 9280
Cipc
Name: CLOCK interacting protein, circadian
Synonyms: 2310044G17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217732
Homologene: 14124
Rap1gds1
Name: RAP1, GTP-GDP dissociation stimulator 1
Synonyms: GDS1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229877
HGNC: HGNC:9859
Homologene: 41422
Eno4
Name: enolase 4
Synonyms: 6430537H07Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226265
Homologene: 18691
Nphp3
Name: nephronophthisis 3 (adolescent)
Synonyms: D330020E01Rik, pcy, nephrocystin 3, 3632410F03Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 74025
HGNC: HGNC:7907
Homologene: 32697
Dmpk
Name: dystrophia myotonica-protein kinase
Synonyms: DM, Dm15
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 13400
HGNC: HGNC:2933
Homologene: 3247
Ttn
Name: titin
Synonyms: connectin, L56, 1100001C23Rik, mdm, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Fat2
Name: FAT atypical cadherin 2
Synonyms: LOC245827, mKIAA0811, Fath2, EMI2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 245827
HGNC: HGNC:3596
Homologene: 1110
Dock10
Name: dedicator of cytokinesis 10
Synonyms: Jr5, Jr4, ZIZ3, 9330153B10Rik, A630054M16Rik, Zizimin3
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210293
Homologene: 45952
Rims1
Name: regulating synaptic membrane exocytosis 1
Synonyms: RIM1, RIM1a, C030033M19Rik, RIM1alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 116837
Homologene: 128399
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239420
Homologene: 65982
Col14a1
Name: collagen, type XIV, alpha 1
Synonyms: 5730412L22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 12818
HGNC: HGNC:2191
Homologene: 18741
Pglyrp1
Name: peptidoglycan recognition protein 1
Synonyms: Tag7, peptidoglycan recognition protein, Tnfsf3l, Tasg7, PGRP-S
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21946
HGNC: HGNC:8904
Homologene: 74539
Vmn1r231
Name: vomeronasal 1 receptor 231
Synonyms: V1re7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 171230
Pbk
Name: PDZ binding kinase
Synonyms: 2810434B10Rik, D14Ertd732e, TOPK
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 52033
Homologene: 32415
Krt18
Name: keratin 18
Synonyms: K18, Endo B, Krt1-18, CK18
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16668
VEGA: 15
HGNC: HGNC:6430
Homologene: 55448
Or8g4
Name: olfactory receptor family 8 subfamily G member 4
Synonyms: GA_x6K02T2PVTD-33447884-33448816, MOR171-30P, Olfr967
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258086
VEGA: 9
HGNC: HGNC:8484
Homologene: 115535
Disp2
Name: dispatched RND transporter family member 2
Synonyms: DispB, B230210L08Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 214240
Homologene: 24916
Itgbl1
Name: integrin, beta-like 1
Synonyms: with EGF-like repeat domains, B930011D01Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 223272
HGNC: HGNC:6164
Homologene: 3519
Or5m13b
Name: olfactory receptor family 5 subfamily M member 13B
Synonyms: GA_x6K02T2Q125-47402610-47403533, MOR196-4, Olfr1026
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258577
Homologene: 73971
Zfp467
Name: zinc finger protein 467
Synonyms: MNCb-3350, EZI, 1190001I08Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68910
Homologene: 10758
Abcc3
Name: ATP-binding cassette, sub-family C member 3
Synonyms: 1700019L09Rik, MRP3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76408
HGNC: HGNC:54
Homologene: 68364
Laptm5
Name: lysosomal-associated protein transmembrane 5
Synonyms: E3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16792
Homologene: 4922
Dzip1l
Name: DAZ interacting protein 1-like
Synonyms: 2610524A10Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72507
Homologene: 12466
Pdss2
Name: prenyl (solanesyl) diphosphate synthase, subunit 2
Synonyms: 5430420P03Rik, kd, mDLP1, PLMP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71365
Homologene: 56885
Lrrc39
Name: leucine rich repeat containing 39
Synonyms: 2010005E21Rik, 9430028I06Rik, Myomasp
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 109245
Homologene: 13668
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384220
Homologene: 104825
Akr1b8
Name: aldo-keto reductase family 1, member B8
Synonyms: Fgrp, Fgfrp
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14187
Homologene: 116462
Lgals3bp
Name: lectin, galactoside-binding, soluble, 3 binding protein
Synonyms: CyCAP, MAC-2BP, 90K, Ppicap, Tango10b
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19039
HGNC: HGNC:6564
Homologene: 4067
Rigi
Name: RNA sensor RIG-I
Synonyms: 6430573D20Rik, RIG-I, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, Ddx58
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230073
Homologene: 32215
Wscd2
Name: WSC domain containing 2
Synonyms: 4933413A10Rik, C530024P05Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 320916
Homologene: 35372
Cdc42ep5
Name: CDC42 effector protein 5
Synonyms: CEP5, 1700027J19Rik, 2010007O02Rik, Borg3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 58804
Homologene: 10984
Upb1
Name: ureidopropionase, beta
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 103149
Homologene: 9471
Fez1
Name: fasciculation and elongation protein zeta 1
Synonyms: UNC-76, UNC76, zygin I
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235180
HGNC: HGNC:3659
Homologene: 21063
Mfap3
Name: microfibrillar-associated protein 3
Synonyms: 2700079M14Rik, 2610509F16Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216760
HGNC: HGNC:7034
Homologene: 4333
Cblc
Name: Casitas B-lineage lymphoma c
Synonyms: Cbl3, 2310079L19Rik, 2310076I21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80794
Homologene: 8108
Slc17a1
Name: solute carrier family 17 (sodium phosphate), member 1
Synonyms: Npt1, NAPI-1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20504
Homologene: 48324
Guca2b
Name: guanylate cyclase activator 2b (retina)
Synonyms: uroguanylin, Gcap2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14916
HGNC: HGNC:4683
Homologene: 5150
AI747448
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Hes3
Name: hes family bHLH transcription factor 3
Synonyms: bHLHb43
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 15207
Homologene: 7358
Gm15455
Name: predicted gene 15455
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 433287
Gm20635
Name: predicted gene 20635
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 105242557
Ear-ps2
Name: eosinophil-associated, ribonuclease A family, pseudogene 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 93743
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 22,288,612 bp
  • A to T, chromosome 1 at 33,837,793 bp
  • C to T, chromosome 1 at 80,515,613 bp
  • G to T, chromosome 1 at 128,236,766 bp
  • A to G, chromosome 2 at 76,767,653 bp
  • T to A, chromosome 2 at 85,918,871 bp
  • G to T, chromosome 2 at 118,791,684 bp
  • C to T, chromosome 3 at 116,570,120 bp
  • T to C, chromosome 3 at 138,927,614 bp
  • T to C, chromosome 3 at 144,911,385 bp
  • A to G, chromosome 4 at 40,203,798 bp
  • A to G, chromosome 4 at 55,008,612 bp
  • C to A, chromosome 4 at 119,656,799 bp
  • T to C, chromosome 4 at 130,933,671 bp
  • T to A, chromosome 4 at 132,670,232 bp
  • T to A, chromosome 4 at 139,408,672 bp
  • T to C, chromosome 4 at 152,287,667 bp
  • A to T, chromosome 5 at 109,339,302 bp
  • T to A, chromosome 5 at 113,551,179 bp
  • A to G, chromosome 5 at 143,391,376 bp
  • G to A, chromosome 6 at 34,363,377 bp
  • A to G, chromosome 6 at 48,439,357 bp
  • T to C, chromosome 6 at 85,620,522 bp
  • G to A, chromosome 7 at 4,151,615 bp
  • A to G, chromosome 7 at 18,884,946 bp
  • A to T, chromosome 7 at 19,088,214 bp
  • C to A, chromosome 7 at 19,796,482 bp
  • A to G, chromosome 7 at 25,288,483 bp
  • T to C, chromosome 7 at 39,536,988 bp
  • A to G, chromosome 7 at 105,764,627 bp
  • A to C, chromosome 7 at 140,153,556 bp
  • T to C, chromosome 8 at 25,563,488 bp
  • T to C, chromosome 8 at 106,700,231 bp
  • T to C, chromosome 9 at 29,179,205 bp
  • T to A, chromosome 9 at 36,870,470 bp
  • T to A, chromosome 9 at 39,750,728 bp
  • C to T, chromosome 9 at 67,395,461 bp
  • A to G, chromosome 9 at 99,663,611 bp
  • A to G, chromosome 9 at 104,022,732 bp
  • A to G, chromosome 9 at 114,464,152 bp
  • A to G, chromosome 10 at 43,345,624 bp
  • A to G, chromosome 10 at 75,415,027 bp
  • T to C, chromosome 11 at 55,285,015 bp
  • T to C, chromosome 11 at 57,528,291 bp
  • C to G, chromosome 11 at 61,535,303 bp
  • C to T, chromosome 11 at 69,320,888 bp
  • A to G, chromosome 11 at 69,736,287 bp
  • C to T, chromosome 11 at 83,335,441 bp
  • T to C, chromosome 11 at 84,280,435 bp
  • T to C, chromosome 11 at 94,350,991 bp
  • C to T, chromosome 11 at 104,356,767 bp
  • C to A, chromosome 11 at 106,247,703 bp
  • C to T, chromosome 11 at 118,398,151 bp
  • T to A, chromosome 12 at 86,952,940 bp
  • A to T, chromosome 12 at 101,885,290 bp
  • T to C, chromosome 13 at 23,880,717 bp
  • C to T, chromosome 13 at 73,627,820 bp
  • G to A, chromosome 14 at 44,047,060 bp
  • C to A, chromosome 14 at 54,643,017 bp
  • G to A, chromosome 14 at 65,811,937 bp
  • T to C, chromosome 14 at 123,966,708 bp
  • T to C, chromosome 15 at 47,913,968 bp
  • A to G, chromosome 15 at 55,372,602 bp
  • G to A, chromosome 15 at 89,303,112 bp
  • A to G, chromosome 15 at 102,031,858 bp
  • T to A, chromosome 16 at 48,925,969 bp
  • T to C, chromosome 17 at 20,890,639 bp
  • T to A, chromosome 17 at 28,007,928 bp
  • C to T, chromosome 17 at 46,028,346 bp
  • T to C, chromosome 17 at 84,426,186 bp
  • A to G, chromosome 19 at 25,603,310 bp
  • T to C, chromosome 19 at 58,945,636 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4696 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
041946-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.