Strain Name:
C57BL/6J-MtgxR4945Btlr/Mmmh
Stock Number:
042542-MU
Citation ID:
RRID:MMRRC_042542-MU
Other Names:
R4945 (G1), C57BL/6J-MtgxR4945Btlr
Major Collection:

Strain Information

Notch2
Name: notch 2
Synonyms: Motch B, N2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18129
HGNC: HGNC:7882
Homologene: 7865
Phax
Name: phosphorylated adaptor for RNA export
Synonyms: p55, 4933427L19Rik, 2810055C14Rik, D18Ertd65e, phosphorylation regulated, Phax, Rnuxa
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 56698
Homologene: 10558
Adgrl3
Name: adhesion G protein-coupled receptor L3
Synonyms: D130075K09Rik, lectomedin 3, LEC3, 5430402I23Rik, Lphn3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 319387
Homologene: 22878
Col6a1
Name: collagen, type VI, alpha 1
Synonyms: Col6a-1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12833
HGNC: HGNC:2211
Homologene: 1391
Morc3
Name: microrchidia 3
Synonyms: 1110051N18Rik, D16Jhu32e, 1110051N18Rik, Zcwcc3
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 338467
Homologene: 32257
Patj
Name: PATJ, crumbs cell polarity complex component
Synonyms: Cipp, Inadl
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12695
Homologene: 72199
Adgrl2
Name: adhesion G protein-coupled receptor L2
Synonyms: Lphh1, Lec1, Lphn2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99633
Homologene: 22712
Med25
Name: mediator complex subunit 25
Synonyms: ESTM2, 2610529E18Rik, 2610034E13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 75613
Homologene: 12614
Atp1b1
Name: ATPase, Na+/K+ transporting, beta 1 polypeptide
Synonyms: sodium/potassium ATPase beta subunit, Atpb-1, Atpb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 11931
HGNC: HGNC:804
Homologene: 37509
Angel2
Name: angel homolog 2
Synonyms: 5730410O10Rik, 2610307I21Rik, D1Ertd654e, D1Ertd396e
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52477
Homologene: 16932
Cep135
Name: centrosomal protein 135
Synonyms: LOC381644, Cep4
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381644
Homologene: 45709
Ttll4
Name: tubulin tyrosine ligase-like family, member 4
Synonyms: 4632407P03Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67534
Homologene: 8764
Rtn1
Name: reticulon 1
Synonyms: Nsp, Rtn1-c, 0710005K15Rik, Rtn1-a, Rtn1-b, 4930441F12Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 104001
Homologene: 49654
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, LOC381026, 9330188B09Rik, D630001M17Rik, 4921513O20Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 66725
Homologene: 18982
Rad51
Name: RAD51 recombinase
Synonyms: Reca, Rad51a
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19361
HGNC: HGNC:9817
Homologene: 2155
Kcnj3
Name: potassium inwardly-rectifying channel, subfamily J, member 3
Synonyms: Kir3.1, GIRK1, Kcnf3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16519
HGNC: HGNC:6264
Homologene: 1687
Cuzd1
Name: CUB and zona pellucida-like domains 1
Synonyms: UTCZP, UO-44, ERG-1, Itmap1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16433
Homologene: 7389
Casp8ap2
Name: caspase 8 associated protein 2
Synonyms: D4Ertd659e, FLASH
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 26885
HGNC: HGNC:1510
Homologene: 8066
Riok3
Name: RIO kinase 3
Synonyms: 1200013N13Rik, Sudd, D18Ertd331e, E130306C24Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 66878
VEGA: 18
Homologene: 2843
Pbrm1
Name: polybromo 1
Synonyms: BAF180, 2610016F04Rik, 2310032M22Rik, Pb1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66923
Homologene: 10044
Tbk1
Name: TANK-binding kinase 1
Synonyms: 1200008B05Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 56480
VEGA: 10
Homologene: 22742
Zfp473
Name: zinc finger protein 473
Synonyms: D030014N22Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243963
Homologene: 18698
Hoxb6
Name: homeobox B6
Synonyms: Hox-2.2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15414
HGNC: HGNC:5117
Homologene: 7366
Adamts13
Name: ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms: LOC279028, vWF-CP mRNA for von Willebrand factor-cleaving
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 279028
HGNC: HGNC:1366
Homologene: 16372
Igfbp7
Name: insulin-like growth factor binding protein 7
Synonyms: mac25, Fstl2, AGM
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 29817
HGNC: HGNC:5476
Homologene: 1193
Aldh1a2
Name: aldehyde dehydrogenase family 1, subfamily A2
Synonyms: Aldh1a7, Raldh2, retinaldehyde dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 19378
Homologene: 68368
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Or51k1
Name: olfactory receptor family 51 subfamily K member 1
Synonyms: GA_x6K02T2PBJ9-6747143-6746193, MOR12-1, Olfr639
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259088
Homologene: 17497
Grk2
Name: G protein-coupled receptor kinase 2
Synonyms: beta ARK, beta ARK1, beta-AR kinase-1, beta-adrenergic receptor kinase-1, Bark-1, Adrbk-1, betaARK1, Adrbk1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 110355
HGNC: HGNC:289
Homologene: 1223
Or5ak24
Name: olfactory receptor family 5 subfamily AK member 24
Synonyms: GA_x6K02T2Q125-46907515-46906571, MOR203-4, Olfr994
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258425
Homologene: 17245
Mroh4
Name: maestro heat-like repeat family member 4
Synonyms: 1700016M24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69439
Homologene: 72545
Rb1cc1
Name: RB1-inducible coiled-coil 1
Synonyms: LaXp180, 2900055E04Rik, Cc1, 5930404L04Rik, Fip200
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12421
Homologene: 7659
Fbn2
Name: fibrillin 2
Synonyms: sy, Sne, Fib-2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 14119
VEGA: 18
HGNC: HGNC:3604
Homologene: 1515
Slc36a2
Name: solute carrier family 36 (proton/amino acid symporter), member 2
Synonyms: PAT2, A530067G19Rik, Tramd1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246049
Homologene: 72100
Wnk2
Name: WNK lysine deficient protein kinase 2
Synonyms: ESTM15, 1810073P09Rik, X83337
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 75607
Homologene: 19155
Gpr179
Name: G protein-coupled receptor 179
Synonyms: 5330439C02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217143
Homologene: 34917
Rfx6
Name: regulatory factor X, 6
Synonyms: 4930572O07Rik, Rfxdc1
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 320995
Homologene: 18318
Pcdhga11
Name: protocadherin gamma subfamily A, 11
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93723
HGNC: HGNC:8698
Homologene: 110934
Dnm3
Name: dynamin 3
Synonyms: B230343F03Rik, 9630020E24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 103967
Homologene: 22906
Tshz2
Name: teashirt zinc finger family member 2
Synonyms: Mtsh2, Sdccag33l, 2900073F20Rik, Zfp218, teashirt2, Tsh2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 228911
Homologene: 35258
Sspo
Name: SCO-spondin
Synonyms: C79529, Scospondin
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243369
Homologene: 45453
Or5m13
Name: olfactory receptor family 5 subfamily M member 13
Synonyms: GA_x6K02T2Q125-47397266-47398205, MOR196-5P, MOR196-6_p, Olfr1025
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258083
Pld2
Name: phospholipase D2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18806
HGNC: HGNC:9068
Homologene: 55672
Rfc3
Name: replication factor C (activator 1) 3
Synonyms: 2810416I22Rik, 38kDa, 38kDa, Recc3
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 69263
HGNC: HGNC:9971
Homologene: 2188
Adam22
Name: a disintegrin and metallopeptidase domain 22
Synonyms: MDC2, 2900022I03Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 11496
HGNC: HGNC:201
Homologene: 37898
Esm1
Name: endothelial cell-specific molecule 1
Synonyms: 0610042H23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 71690
HGNC: HGNC:3466
Homologene: 5107
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Zfp536
Name: zinc finger protein 536
Synonyms: 9630010P11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243937
Homologene: 8813
Mex3b
Name: mex3 RNA binding family member B
Synonyms: 4931439A04Rik, Rkhd3
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108797
Homologene: 13570
Pde6a
Name: phosphodiesterase 6A, cGMP-specific, rod, alpha
Synonyms: Pdea
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 225600
HGNC: HGNC:8785
Homologene: 380
Skint8
Name: selection and upkeep of intraepithelial T cells 8
Synonyms: OTTMUSG00000009475
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 639774
Homologene: 106613
Txndc15
Name: thioredoxin domain containing 15
Synonyms: 2310047H23Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69672
VEGA: 13
Homologene: 32594
Cerk
Name: ceramide kinase
Synonyms: D330016D08Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 223753
Homologene: 11247
Or8b44
Name: olfactory receptor family 8 subfamily B member 44
Synonyms: GA_x6K02T2PVTD-32204729-32205661, MOR165-5, Olfr907
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258801
VEGA: 9
Homologene: 27268
Vmn2r49
Name: vomeronasal 2, receptor 49
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 625605
Homologene: 113703
Tchhl1
Name: trichohyalin-like 1
Synonyms: S100a17, Thhl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71325
Homologene: 84625
Sorcs3
Name: sortilin-related VPS10 domain containing receptor 3
Synonyms: 6330404A12Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 66673
VEGA: 19
Homologene: 8986
Vmn1r172
Name: vomeronasal 1 receptor 172
Synonyms: V3R9, V1rd9
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 81010
Homologene: 79577
Lrif1
Name: ligand dependent nuclear receptor interacting factor 1
Synonyms: 2010012G17Rik, 4933421E11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 321000
Homologene: 10160
Or8k37
Name: olfactory receptor family 8 subfamily K member 37
Synonyms: GA_x6K02T2Q125-48121788-48120847, MOR192-3, MOR192-2, Olfr1084
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258235
Homologene: 104285
Ift27
Name: intraflagellar transport 27
Synonyms: 2600013G09Rik, Rabl4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 67042
VEGA: 15
Homologene: 4998
Or10a5
Name: olfactory receptor family 10 subfamily A member 5
Synonyms: GA_x6K02T2PBJ9-9415724-9416677, MOR263-1, P3, Olfr713
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259036
Homologene: 17470
Or2l13b
Name: olfactory receptor family 2 subfamily L member 13B
Synonyms: GA_x54KRFPKG5P-15979009-15978071, MOR271-1, Olfr168
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258354
Homologene: 128057
Tgfbr2
Name: transforming growth factor, beta receptor II
Synonyms: TbetaR-II, TbetaRII, 1110020H15Rik, TBR-II
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 21813
VEGA: 9
Homologene: 2435
Trim8
Name: tripartite motif-containing 8
Synonyms: Rnf27, GERP
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 93679
VEGA: 19
Homologene: 12795
Mkx
Name: mohawk homeobox
Synonyms: 9430023B20Rik, Irxl1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 210719
Homologene: 72239
Rabl3
Name: RAB, member RAS oncogene family-like 3
Synonyms: 4930553C05Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 67657
Homologene: 12171
Cmtr2
Name: cap methyltransferase 2
Synonyms: C730036L12Rik, Ftsjd1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234728
Homologene: 10144
Zar1-ps
Name: zygote arrest 1, pseudogene
Synonyms: Gm15847
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 102637480
Or8b38
Name: olfactory receptor family 8 subfamily B member 38
Synonyms: GA_x6K02T2PVTD-31740639-31741568, MOR162-12, Olfr885
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 257885
Homologene: 79400
Vmn1r55
Name: vomeronasal 1 receptor 55
Synonyms: LOC236535, LOC384522, V1rd5
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 384522
Homologene: 41799
Ighv1-49
Name: immunoglobulin heavy variable 1-49
Synonyms: Gm16830
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 629925
Zfp853
Name: zinc finger protein 853
Synonyms: LOC330230
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 330230
RP24-511F2.4
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Ighv8-8
Name: immunoglobulin heavy variable 8-8
Synonyms: immunoglobulin heavy variable V8-8, Ighv8-8, Gm9740
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 780938
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 6,249,627 bp
  • A to G, chromosome 1 at 74,688,606 bp
  • C to T, chromosome 1 at 162,477,921 bp
  • A to G, chromosome 1 at 164,438,298 bp
  • C to T, chromosome 1 at 190,939,199 bp
  • G to A, chromosome 2 at 26,986,610 bp
  • T to A, chromosome 2 at 55,437,578 bp
  • T to C, chromosome 2 at 85,430,551 bp
  • T to A, chromosome 2 at 85,918,573 bp
  • T to C, chromosome 2 at 86,639,489 bp
  • T to A, chromosome 2 at 119,127,148 bp
  • A to G, chromosome 2 at 169,883,874 bp
  • A to T, chromosome 3 at 93,471,576 bp
  • A to G, chromosome 3 at 98,111,721 bp
  • A to C, chromosome 3 at 106,735,753 bp
  • A to T, chromosome 3 at 123,552,552 bp
  • T to A, chromosome 3 at 148,823,036 bp
  • T to C, chromosome 3 at 152,391,675 bp
  • T to A, chromosome 4 at 32,631,163 bp
  • A to T, chromosome 4 at 98,495,064 bp
  • T to C, chromosome 4 at 111,939,608 bp
  • G to T, chromosome 5 at 8,088,740 bp
  • G to T, chromosome 5 at 8,088,741 bp
  • A to C, chromosome 5 at 73,013,577 bp
  • A to G, chromosome 5 at 76,597,428 bp
  • T to C, chromosome 5 at 77,351,257 bp
  • C to A, chromosome 5 at 81,512,048 bp
  • A to T, chromosome 5 at 109,677,075 bp
  • C to A, chromosome 5 at 143,288,829 bp
  • T to C, chromosome 5 at 151,642,985 bp
  • A to G, chromosome 6 at 48,467,087 bp
  • A to G, chromosome 7 at 5,147,106 bp
  • T to A, chromosome 7 at 9,986,287 bp
  • T to A, chromosome 7 at 23,660,320 bp
  • G to T, chromosome 7 at 37,569,736 bp
  • T to C, chromosome 7 at 44,734,564 bp
  • T to C, chromosome 7 at 44,883,102 bp
  • A to T, chromosome 7 at 82,870,174 bp
  • G to A, chromosome 7 at 104,012,378 bp
  • A to T, chromosome 7 at 107,036,319 bp
  • A to G, chromosome 7 at 131,316,621 bp
  • T to C, chromosome 8 at 110,221,433 bp
  • T to C, chromosome 9 at 26,920,595 bp
  • G to T, chromosome 9 at 38,061,772 bp
  • A to T, chromosome 9 at 38,499,289 bp
  • C to A, chromosome 9 at 71,215,916 bp
  • A to T, chromosome 9 at 116,131,565 bp
  • T to G, chromosome 10 at 51,726,851 bp
  • A to G, chromosome 10 at 76,712,272 bp
  • T to C, chromosome 10 at 121,551,269 bp
  • C to A, chromosome 11 at 55,174,694 bp
  • T to A, chromosome 11 at 70,555,698 bp
  • A to G, chromosome 11 at 96,299,259 bp
  • T to C, chromosome 11 at 97,349,718 bp
  • G to T, chromosome 12 at 72,217,484 bp
  • C to A, chromosome 12 at 115,055,408 bp
  • C to T, chromosome 12 at 115,294,261 bp
  • C to T, chromosome 13 at 49,057,246 bp
  • T to A, chromosome 13 at 55,718,165 bp
  • T to G, chromosome 13 at 113,210,145 bp
  • T to A, chromosome 14 at 31,052,216 bp
  • G to T, chromosome 15 at 74,612,008 bp
  • A to G, chromosome 15 at 78,164,254 bp
  • C to G, chromosome 15 at 86,156,601 bp
  • T to C, chromosome 15 at 91,804,920 bp
  • C to A, chromosome 16 at 19,530,557 bp
  • T to C, chromosome 16 at 37,541,858 bp
  • A to T, chromosome 16 at 93,871,194 bp
  • T to C, chromosome 18 at 7,000,657 bp
  • A to G, chromosome 18 at 12,128,915 bp
  • A to G, chromosome 18 at 37,758,032 bp
  • G to T, chromosome 18 at 56,575,991 bp
  • T to A, chromosome 18 at 58,050,253 bp
  • T to C, chromosome 18 at 61,234,718 bp
  • A to G, chromosome 19 at 4,290,447 bp
  • A to G, chromosome 19 at 46,502,775 bp
  • T to C, chromosome 19 at 48,764,148 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R4945 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042542-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.