Strain Name:
C57BL/6J-MtgxR5395Btlr/Mmmh
Stock Number:
042967-MU
Citation ID:
RRID:MMRRC_042967-MU
Other Names:
R5395 (G1), C57BL/6J-MtgxR5395Btlr
Major Collection:

Strain Information

Tyr
Name: tyrosinase
Synonyms: skc35, Oca1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22173
Homologene: 30969
Itgb8
Name: integrin beta 8
Synonyms: 4832412O06Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 320910
HGNC: HGNC:6163
Homologene: 18567
Nes
Name: nestin
Synonyms: Ifaprc2, Marc2, RC2, ESTM46
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18008
HGNC: HGNC:7756
Homologene: 136487
Smyd1
Name: SET and MYND domain containing 1
Synonyms: Bop, 4632404M21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 12180
Homologene: 7645
Gdnf
Name: glial cell line derived neurotrophic factor
Synonyms: glial cell line-derived neurotrophic factor
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 14573
VEGA: 15
HGNC: HGNC:4232
Homologene: 433
Snd1
Name: staphylococcal nuclease and tudor domain containing 1
Synonyms: p100 co-activator, Tudor-SN
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 56463
Homologene: 8665
Rangap1
Name: RAN GTPase activating protein 1
Synonyms: Fug1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 19387
VEGA: 15
HGNC: HGNC:9854
Homologene: 55700
Zc3h7b
Name: zinc finger CCCH type containing 7B
Synonyms: Scrg3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 20286
VEGA: 15
Homologene: 9735
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Rnf169
Name: ring finger protein 169
Synonyms: 2900057K09Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 108937
Homologene: 47510
Ptpn21
Name: protein tyrosine phosphatase, non-receptor type 21
Synonyms: PTPD1, PTPRL10
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 24000
VEGA: 12
HGNC: HGNC:9651
Homologene: 5110
Mcm5
Name: minichromosome maintenance complex component 5
Synonyms: mCD46, Cdc46, Mcmd5
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 17218
HGNC: HGNC:6948
Homologene: 4904
Trim24
Name: tripartite motif-containing 24
Synonyms: Tif1a, TIF1alpha, D430004I05Rik, A130082H20Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 21848
Homologene: 20830
Phkb
Name: phosphorylase kinase beta
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102093
HGNC: HGNC:8927
Homologene: 247
Actn1
Name: actinin, alpha 1
Synonyms: 3110023F10Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 109711
VEGA: 12
HGNC: HGNC:163
Homologene: 55553
Rapgef1
Name: Rap guanine nucleotide exchange factor (GEF) 1
Synonyms: Grf2, 4932418O06Rik, C3G
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107746
HGNC: HGNC:4568
Homologene: 50501
Sin3a
Name: transcriptional regulator, SIN3A (yeast)
Synonyms: mSin3A, Sin3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 20466
Homologene: 32124
Bcas3
Name: BCAS3 microtubule associated cell migration factor
Synonyms: 2610028P08Rik, 1500019F07Rik, K20D4, Phaf2, breast carcinoma amplified sequence 3, rudhira
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192197
Homologene: 9778
Slc9a8
Name: solute carrier family 9 (sodium/hydrogen exchanger), member 8
Synonyms: NHE8, 1200006P13Rik, 6430709P13Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77031
Homologene: 75041
Nol6
Name: nucleolar protein family 6 (RNA-associated)
Synonyms: Nrap
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230082
Homologene: 41505
Mcm9
Name: minichromosome maintenance 9 homologous recombination repair factor
Synonyms: Mcmdc1, 9030408O17Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 71567
VEGA: 10
Homologene: 13546
Spag9
Name: sperm associated antigen 9
Synonyms: 3110018C07Rik, Mapk8ip4, 4831406C20Rik, syd1, JLP, 4733401I23Rik, JIP4
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 70834
Homologene: 2954
Six6
Name: sine oculis-related homeobox 6
Synonyms: Optx2, Six9
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 20476
Homologene: 7220
Fev
Name: FEV transcription factor, ETS family member
Synonyms: Pex1, Pet1, mPet-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 260298
Homologene: 9706
Morc2a
Name: microrchidia 2A
Synonyms: 8430403M08Rik, Zcwcc1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 74522
Homologene: 8966
Dennd1a
Name: DENN domain containing 1A
Synonyms: 6030446I19Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227801
Homologene: 17141
Gm14325
Name: predicted gene 14325
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 329575
Homologene: 134324
Thsd1
Name: thrombospondin, type I, domain 1
Synonyms: Tmtsp, 4833423O18Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 56229
Homologene: 10264
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: wmfl, Flk-2, Flk2, Flt-3, CD135
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Pou4f2
Name: POU domain, class 4, transcription factor 2
Synonyms: Brn-3.2, Pou4f-rs1, Brn-3b, mBrn3-3R, Brn3b
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 18997
HGNC: HGNC:9219
Homologene: 20959
Slc35d1
Name: solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Synonyms: UGTREL7
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242585
Homologene: 22870
Slc7a8
Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Synonyms: LAT2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 50934
VEGA: 14
Homologene: 8166
Ndst3
Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
Synonyms: 4930511P15Rik, 4921531K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83398
HGNC: HGNC:7682
Homologene: 3513
Slc45a2
Name: solute carrier family 45, member 2
Synonyms: Dbr, blanc-sale, dominant brown, Oca4, Matp, Aim-1, Aim1, bls
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 22293
Homologene: 9412
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: b2b1554Clo, A2mr, CD91
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Abca4
Name: ATP-binding cassette, sub-family A member 4
Synonyms: Rim protein, RmP, D430003I15Rik, Abc10
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 11304
HGNC: HGNC:34
Homologene: 298
Tnfsf9
Name: tumor necrosis factor (ligand) superfamily, member 9
Synonyms: Cd137l, 4-1BBL, Ly63l, 4-1BB-L, 4-1BB ligand
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21950
VEGA: 17
Homologene: 137221
Nfatc1
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Synonyms: 2210017P03Rik, NF-ATc, NFATc, NFAT2
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 18018
VEGA: 18
HGNC: HGNC:7775
Homologene: 32336
Cyp4f40
Name: cytochrome P450, family 4, subfamily f, polypeptide 40
Synonyms: EG631304
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 631304
VEGA: 17
Homologene: 117991
Wdr64
Name: WD repeat domain 64
Synonyms: 4930511H01Rik, 4930415O10Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75820
Homologene: 51634
Slc20a1
Name: solute carrier family 20, member 1
Synonyms: Glvr-1, Glvr1, PiT-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20515
Homologene: 38049
Ly75
Name: lymphocyte antigen 75
Synonyms: DEC-205, CD205
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17076
Homologene: 31085
Fcrl6
Name: Fc receptor-like 6
Synonyms: mIFGP6, moFcRH6, FcRH6, ENSMUSG00000070504
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 677296
Homologene: 88414
Or10j7
Name: olfactory receptor family 10 subfamily J member 7
Synonyms: GA_x6K02T2R7CC-664297-665229, Olfr1406, MOR267-5
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 258758
Homologene: 133644
Arhgef10l
Name: Rho guanine nucleotide exchange factor 10-like
Synonyms: 2810441C07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 72754
Homologene: 10017
Clk3
Name: CDC-like kinase 3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 102414
VEGA: 9
HGNC: HGNC:2071
Homologene: 101534
Cog2
Name: component of oligomeric golgi complex 2
Synonyms: 1190002B08Rik, 2700012E02Rik, Cog2
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 76332
HGNC: HGNC:6546
Homologene: 7206
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244114
Homologene: 115466
Neu2
Name: neuraminidase 2
Synonyms: MTS, cystolic sialidase, MBS, brain sialidase, MSS
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 23956
HGNC: HGNC:7759
Homologene: 3927
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Gjc2
Name: gap junction protein, gamma 2
Synonyms: Cx47, B230382L12Rik, Gja12, connexin 47
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 118454
Homologene: 10715
Atp13a4
Name: ATPase type 13A4
Synonyms: 9330174J19Rik, 4631413J11Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224079
Homologene: 75330
Hps1
Name: HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms: 6030422N11Rik, Hermansky-Pudlak syndrome 1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 192236
HGNC: HGNC:5163
Homologene: 163
Ccng2
Name: cyclin G2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12452
HGNC: HGNC:1593
Homologene: 3208
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319734
Homologene: 26544
Vmn2r55
Name: vomeronasal 2, receptor 55
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100042499
Homologene: 104040
Gm1110
Name: predicted gene 1110
Synonyms: LOC382064
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 382064
VEGA: 9
Homologene: 78608
Adamdec1
Name: ADAM-like, decysin 1
Synonyms: Dcsn, 2210414L24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 58860
VEGA: 14
Homologene: 8711
Ankzf1
Name: ankyrin repeat and zinc finger domain containing 1
Synonyms: D1Ertd161e, 2810025E10Rik, 1300008P06Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 52231
Homologene: 41225
Usp43
Name: ubiquitin specific peptidase 43
Synonyms: C630032K07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216835
Homologene: 129879
Raly
Name: hnRNP-associated with lethal yellow
Synonyms: Merc
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19383
Homologene: 7216
Piwil2
Name: piwi-like RNA-mediated gene silencing 2
Synonyms: Miwi like, mili
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57746
VEGA: 14
Homologene: 23071
Prkd1
Name: protein kinase D1
Synonyms: Pkcm, Prkcm, PKD1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18760
VEGA: 12
HGNC: HGNC:9407
Homologene: 55680
Agbl5
Name: ATP/GTP binding protein-like 5
Synonyms: 9430057O19Rik, Ccp5
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231093
Homologene: 11053
Sdr16c5
Name: short chain dehydrogenase/reductase family 16C, member 5
Synonyms: Rdhe2, Scdr9
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242285
Homologene: 15039
Apoo-ps
Name: apolipoprotein O, pseudogene
Synonyms: Apoo, EG621156
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 621156
VEGA: 13
Birc3
Name: baculoviral IAP repeat-containing 3
Synonyms: cIAP2, cIAP-2, MIHC, HIAP2, MIAP2, IAP2, RNF49, Api2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11796
HGNC: HGNC:591
Homologene: 899
Inca1
Name: inhibitor of CDK, cyclin A1 interacting protein 1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103844
Homologene: 19481
Icam2
Name: intercellular adhesion molecule 2
Synonyms: Icam-2, CD102
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15896
HGNC: HGNC:5345
Homologene: 675
Zfp493
Name: zinc finger protein 493
Synonyms: 2900054J07Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 72958
Gdf9
Name: growth differentiation factor 9
Synonyms: Gdf-9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14566
HGNC: HGNC:4224
Homologene: 3851
Zpbp2
Name: zona pellucida binding protein 2
Synonyms: 1700017D11Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 69376
Homologene: 18892
Gnb2
Name: guanine nucleotide binding protein (G protein), beta 2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 14693
HGNC: HGNC:4398
Homologene: 68451
Zfp825
Name: zinc finger protein 825
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 235956
Gm16551
Name: predicted gene 16551
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 100503019
Gm14488
Name: predicted gene 14488
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100038700
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 74,882,664 bp
  • T to C, chromosome 1 at 75,197,939 bp
  • T to A, chromosome 1 at 87,596,675 bp
  • G to T, chromosome 1 at 172,598,720 bp
  • A to T, chromosome 1 at 173,183,680 bp
  • T to A, chromosome 1 at 175,755,598 bp
  • T to A, chromosome 2 at 29,737,965 bp
  • A to G, chromosome 2 at 30,714,940 bp
  • A to T, chromosome 2 at 37,802,128 bp
  • A to T, chromosome 2 at 60,365,111 bp
  • A to T, chromosome 2 at 129,208,337 bp
  • T to A, chromosome 2 at 154,864,007 bp
  • T to A, chromosome 2 at 167,467,722 bp
  • G to A, chromosome 2 at 177,832,984 bp
  • C to A, chromosome 3 at 87,971,766 bp
  • A to G, chromosome 3 at 122,080,941 bp
  • A to T, chromosome 3 at 123,556,756 bp
  • T to C, chromosome 4 at 4,016,277 bp
  • G to A, chromosome 4 at 41,118,392 bp
  • C to T, chromosome 4 at 103,211,375 bp
  • T to C, chromosome 4 at 140,570,290 bp
  • C to A, chromosome 5 at 30,890,338 bp
  • T to C, chromosome 5 at 93,269,398 bp
  • A to G, chromosome 5 at 137,528,526 bp
  • A to G, chromosome 5 at 147,354,823 bp
  • T to A, chromosome 6 at 28,526,184 bp
  • T to G, chromosome 6 at 37,957,744 bp
  • T to G, chromosome 6 at 71,219,390 bp
  • T to C, chromosome 6 at 119,271,418 bp
  • T to C, chromosome 7 at 12,651,947 bp
  • A to G, chromosome 7 at 85,750,897 bp
  • C to A, chromosome 7 at 87,472,490 bp
  • A to T, chromosome 7 at 99,935,160 bp
  • G to A, chromosome 8 at 22,243,691 bp
  • G to A, chromosome 8 at 75,123,026 bp
  • T to A, chromosome 8 at 78,435,072 bp
  • A to G, chromosome 8 at 86,017,468 bp
  • T to A, chromosome 8 at 124,545,221 bp
  • T to C, chromosome 9 at 7,861,174 bp
  • T to C, chromosome 9 at 26,889,632 bp
  • G to A, chromosome 9 at 57,105,673 bp
  • G to A, chromosome 9 at 57,753,339 bp
  • A to G, chromosome 9 at 74,849,180 bp
  • A to T, chromosome 10 at 53,538,692 bp
  • T to A, chromosome 10 at 74,185,287 bp
  • T to C, chromosome 10 at 107,817,138 bp
  • T to C, chromosome 10 at 127,595,297 bp
  • G to A, chromosome 11 at 3,688,232 bp
  • T to C, chromosome 11 at 53,433,797 bp
  • A to T, chromosome 11 at 59,177,489 bp
  • T to A, chromosome 11 at 67,897,358 bp
  • C to T, chromosome 11 at 70,690,438 bp
  • T to C, chromosome 11 at 85,825,249 bp
  • T to G, chromosome 11 at 94,091,751 bp
  • T to A, chromosome 11 at 98,558,213 bp
  • A to T, chromosome 11 at 106,382,473 bp
  • T to C, chromosome 12 at 50,391,432 bp
  • T to A, chromosome 12 at 72,941,701 bp
  • T to A, chromosome 12 at 80,170,703 bp
  • T to G, chromosome 12 at 98,715,117 bp
  • A to C, chromosome 12 at 119,170,741 bp
  • T to A, chromosome 13 at 67,783,846 bp
  • T to C, chromosome 13 at 74,480,546 bp
  • T to A, chromosome 13 at 107,414,493 bp
  • A to G, chromosome 14 at 7,883,881 bp
  • C to A, chromosome 14 at 54,733,277 bp
  • A to C, chromosome 14 at 68,570,903 bp
  • G to T, chromosome 14 at 70,395,397 bp
  • T to A, chromosome 15 at 7,834,684 bp
  • C to T, chromosome 15 at 11,027,785 bp
  • A to G, chromosome 15 at 81,706,446 bp
  • G to A, chromosome 15 at 81,772,501 bp
  • A to T, chromosome 16 at 29,420,888 bp
  • A to G, chromosome 16 at 29,456,604 bp
  • C to T, chromosome 17 at 32,669,853 bp
  • C to A, chromosome 17 at 57,105,592 bp
  • G to A, chromosome 18 at 80,636,020 bp
  • T to C, chromosome 19 at 42,760,572 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5395 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

The donor or their institution limits the distribution to non-profit institutions only.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
042967-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality, nor genotype, of this material. Our expertise in reviving mice from various qualities of frozen sperm and embryos, using methods like IVF and ICSI, gives us confidence in successful recoveries in most cases. However, due to the uncertain quality of these samples, we'll limit revival attempts to two per order. Additional attempts are available for a fee, on top of standard charges, if requested. It's important to note that some strains may lack the expected mutation, so we can't assure successful order fulfillment until we attempt to revive the strain.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.