Strain Name:
C57BL/6J-MtgxR5135Btlr/Mmmh
Stock Number:
043261-MU
Citation ID:
RRID:MMRRC_043261-MU
Other Names:
R5135 (G1)
Major Collection:

Strain Information

Kitl
Name: kit ligand
Synonyms: stem cell factor, Sl, grizzle-belly, Steel factor, SLF, SF, Mgf, Gb, SCF, Kitlg, blz, Steel
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17311
HGNC: HGNC:6343
Homologene: 692
Zfa-ps
Name: zinc finger protein, autosomal, pseudogene
Synonyms: Zfa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 22639
Zic4
Name: zinc finger protein of the cerebellum 4
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 22774
Homologene: 32075
Gcm2
Name: glial cells missing homolog 2
Synonyms: Gcm1-rs2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 107889
VEGA: 13
HGNC: HGNC:4198
Homologene: 3490
Kdm5b
Name: lysine demethylase 5B
Synonyms: Rb-Bp2, 2210016I17Rik, Jarid1b, 2010009J12Rik, D1Ertd202e, Plu1, PLU-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 75605
Homologene: 48448
Kpna4
Name: karyopherin subunit alpha 4
Synonyms: importin alpha 3, 1110058D08Rik, IPOA3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 16649
HGNC: HGNC:6397
Homologene: 20521
Slc4a2
Name: solute carrier family 4 (anion exchanger), member 2
Synonyms: B3RP, Ae2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20535
Homologene: 128699
Pdlim5
Name: PDZ and LIM domain 5
Synonyms: Enh3, Enh2, Enh, 1110001A05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 56376
Homologene: 21289
Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Synonyms: Sac1p, SAC1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 83493
VEGA: 9
Homologene: 6320
Larp4b
Name: La ribonucleoprotein 4B
Synonyms: Larp5, D13Wsu64e, A130023E24Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 217980
Homologene: 18195
Ncapg2
Name: non-SMC condensin II complex, subunit G2
Synonyms: Luzp5, Mtb, 5830426I05Rik, mCAP-G2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 76044
VEGA: 12
Homologene: 9820
Dlgap5
Name: DLG associated protein 5
Synonyms: Hurp, C86398, Dlg7
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218977
Homologene: 8840
Zc3h11a
Name: zinc finger CCCH type containing 11A
Synonyms: G630041M05Rik, 1110003F06Rik, 5730454B08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 70579
Homologene: 8888
Sdad1
Name: SDA1 domain containing 1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231452
Homologene: 6036
Bltp3b
Name: bridge-like lipid transfer protein family member 3B
Synonyms: 4930506D01Rik, Uhrf1bp1l, E030041M21Rik, 2010319N22Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 75089
VEGA: 10
Homologene: 12590
Tanc2
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
Synonyms: 3526402J09Rik, 5730590C14Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 77097
Homologene: 64680
Apaf1
Name: apoptotic peptidase activating factor 1
Synonyms: 6230400I06Rik, Apaf1l
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11783
HGNC: HGNC:576
Homologene: 7626
Ryr2
Name: ryanodine receptor 2, cardiac
Synonyms: 9330127I20Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20191
VEGA: 13
Homologene: 37423
Cdc42bpg
Name: CDC42 binding protein kinase gamma
Synonyms: MRCKgamma
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240505
Homologene: 28384
Iqsec3
Name: IQ motif and Sec7 domain 3
Synonyms: synarfGEF, BRAG3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243621
Homologene: 46091
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Lama5
Name: laminin, alpha 5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 16776
HGNC: HGNC:6485
Homologene: 4060
Sema6a
Name: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
Synonyms: A730020P05Rik, sema, Sema6A-1, VIa, Semaq
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 20358
Homologene: 32426
Clca4a
Name: chloride channel accessory 4A
Synonyms: Clca6, 9130020L07Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99663
HGNC: HGNC:2018
Homologene: 40808
Edrf1
Name: erythroid differentiation regulatory factor 1
Synonyms: 2700050L05Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 214764
Homologene: 27985
Klhl26
Name: kelch-like 26
Synonyms: C630013N10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234378
Homologene: 41247
Akap2
Name: A kinase (PRKA) anchor protein 2
Synonyms: B230340M18Rik, AKAP-KL
Type: Gene
Species: Mouse
Chromosome: 4
Bhmt
Name: betaine-homocysteine methyltransferase
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12116
HGNC: HGNC:1047
Homologene: 1295
Hormad1
Name: HORMA domain containing 1
Synonyms: 4921522K05Rik, Nohma
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 67981
Homologene: 69415
Myo16
Name: myosin XVI
Synonyms: BM140241, Nyap3, C230040D10Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244281
Homologene: 34710
Dnah12
Name: dynein, axonemal, heavy chain 12
Synonyms: Dnahc12, HL19, DLP12, LOC380889, Dnahc7l, 4921531P07Rik, Hdhc3, DHC3, HL-19
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 110083
HGNC: HGNC:2943
Homologene: 56821
Liph
Name: lipase, member H
Synonyms: PLA1B, mPA-PLA1, D16Wsu119e, C130037N08Rik, LPDLR, Lpdlr
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 239759
VEGA: 16
Homologene: 71802
Oc90
Name: otoconin 90
Synonyms: PLA2L, Ocn-95, Pla2ll
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 18256
HGNC: HGNC:8100
Homologene: 19021
Celsr2
Name: cadherin, EGF LAG seven-pass G-type receptor 2
Synonyms: EGFL2, mfmi1, Adgrc2, flamingo
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 53883
HGNC: HGNC:3231
Homologene: 1078
Naip2
Name: NLR family, apoptosis inhibitory protein 2
Synonyms: Naip-rs6, Naip2, Birc1b
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 17948
HGNC: HGNC:7634
Homologene: 136092
Or4a80
Name: olfactory receptor family 4 subfamily A member 80
Synonyms: MOR231-19P, MOR231-19P, Olfr1559-ps1, Olfr1253-ps1, Olfr1253, MOR231-18, GA_x6K02T2Q125-51193814-51192857
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258370
Dock3
Name: dedicator of cyto-kinesis 3
Synonyms: Moca, PBP
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208869
HGNC: HGNC:2989
Homologene: 21030
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: OTTMUSG00000005786, LOC380698
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380698
Homologene: 70869
Eif2ak2
Name: eukaryotic translation initiation factor 2-alpha kinase 2
Synonyms: Tik, IFN-induced and double-stranded RNA-activated kinase, eIF-2 alpha, Prkr, eIF-2 alpha, 4732414G15Rik, IFN- type I-induced and dsRNA-activated kinase, 2310047A08Rik, dsRNA-activated kinase, Pkr
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19106
HGNC: HGNC:9437
Homologene: 48134
Ankrd50
Name: ankyrin repeat domain 50
Synonyms: E430012K20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 99696
Homologene: 129859
Slc5a4a
Name: solute carrier family 5, member 4a
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 64452
VEGA: 10
Plcxd1
Name: phosphatidylinositol-specific phospholipase C, X domain containing 1
Synonyms: A330045H12Rik, LOC231597
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 403178
Homologene: 138628
Zfp747
Name: zinc finger protein 747
Synonyms: 6430604K15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 269997
Homologene: 118005
Gm4787
Name: predicted gene 4787
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 214321
Homologene: 86950
Sec11a
Name: SEC11 homolog A, signal peptidase complex subunit
Synonyms: sid2895, Spc18, 1810012E07Rik, 18kDa, Sec11l1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56529
Homologene: 55536
Col22a1
Name: collagen, type XXII, alpha 1
Synonyms: C80743, 2310067L16Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69700
Homologene: 43567
Dhx30
Name: DExH-box helicase 30
Synonyms: 2810477H02Rik, C130058C04Rik, DEAH (Asp-Glu-Ala-His) box polypeptide 30, Ddx30, helG
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72831
Homologene: 15779
Adam10
Name: a disintegrin and metallopeptidase domain 10
Synonyms: kuzbanian, kuz, 1700031C13Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 11487
HGNC: HGNC:188
Homologene: 865
Npc1l1
Name: NPC1 like intracellular cholesterol transporter 1
Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237636
HGNC: HGNC:7898
Homologene: 56585
Or4e1
Name: olfactory receptor family 4 subfamily E member 1
Synonyms: Olfr1508, GA_x6K02T2RJGY-520647-521579, MOR244-2, MOR244-4, MOR10
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 57270
HGNC: HGNC:8296
Homologene: 10737
Gm10722
Name: predicted gene 10722
Type: Gene
Species: Mouse
Chromosome: 9
4930553M12Rik
Name: RIKEN cDNA 4930553M12 gene
Type: Gene
Species: Mouse
Chromosome: 4
Pex5l
Name: peroxisomal biogenesis factor 5-like
Synonyms: PXR2, Pex2, 1700016J08Rik, TRIP8b
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 58869
Homologene: 9562
Serpinb6c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6c
Synonyms: Spi3C, ovalbumin, SPIC
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 97848
HGNC: HGNC:8950
Grip2
Name: glutamate receptor interacting protein 2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243547
Homologene: 16327
Alox5
Name: arachidonate 5-lipoxygenase
Synonyms: 5LO, 5-LOX, 5LX
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 11689
HGNC: HGNC:435
Homologene: 561
Aldh18a1
Name: aldehyde dehydrogenase 18 family, member A1
Synonyms: 2810433K04Rik, Pycs
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 56454
HGNC: HGNC:9722
Homologene: 2142
Ap2s1
Name: adaptor-related protein complex 2, sigma 1 subunit
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232910
HGNC: HGNC:565
Homologene: 3001
Lrrc31
Name: leucine rich repeat containing 31
Synonyms: E230002P03Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 320352
Cel
Name: carboxyl ester lipase
Synonyms: 1810036E18Rik, BAL
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12613
HGNC: HGNC:1848
Homologene: 37529
H2-Ob
Name: histocompatibility 2, O region beta locus
Synonyms: H2-Ab2, vic1, H-2I, Ob, H2-Ab, A-beta2, A-beta-2, H-2Ob, H2-IAb2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 15002
HGNC: HGNC:4937
Homologene: 1602
Usp36
Name: ubiquitin specific peptidase 36
Synonyms: 2700002L06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 72344
Homologene: 11828
Stard13
Name: StAR related lipid transfer domain containing 13
Synonyms: GT650, DLC2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243362
Homologene: 64844
Gm4846
Name: predicted gene 4846
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226601
Homologene: 136281
1700056E22Rik
Name: RIKEN cDNA 1700056E22 gene
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 73363
Homologene: 137387
Pramel12
Name: PRAME like 12
Synonyms: Pramef8, 4732496O08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242736
Homologene: 128393
Zfp663
Name: zinc finger protein 663
Synonyms: LOC381405, Gm1008
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 381405
Homologene: 128277
Prl8a1
Name: prolactin family 8, subfamily a, member 1
Synonyms: Plpcd, PLP-Cd, Prlpc4, 3830403L08Rik, 1600017L04Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 73244
Or1e16
Name: olfactory receptor family 1 subfamily E member 16
Synonyms: MOR135-13, GA_x6K02T2P1NL-3556334-3555390, I54, Olfr1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258923
Homologene: 115482
Cyp4a14
Name: cytochrome P450, family 4, subfamily a, polypeptide 14
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 13119
Homologene: 134697
Mmel1
Name: membrane metallo-endopeptidase-like 1
Synonyms: Nep2, Nl1, SEP, NEPLP gamma, NEPLP beta, NEPLP alpha, Mell1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 27390
Homologene: 22778
Evi2a
Name: ecotropic viral integration site 2a
Synonyms: Evi2, Evi-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 14017
HGNC: HGNC:3499
Homologene: 49234
Lrrc36
Name: leucine rich repeat containing 36
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 270091
Homologene: 23090
Fzd4
Name: frizzled class receptor 4
Synonyms: Fz4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 14366
HGNC: HGNC:4042
Homologene: 7325
Gm5414
Name: predicted gene 5414
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 406223
VEGA: 15
Ighv2-1
Name: immunoglobulin heavy variable 2-1
Synonyms: Gm17347
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 777684
Gm6185
Name: predicted gene 6185
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 620839
Zfp1002
Name: zinc finger protein 1002
Synonyms: Gm21994
Type: Gene
Species: Mouse
Chromosome: 2
Tfap2e
Name: transcription factor AP-2, epsilon
Synonyms: AP-2e, Tcfap2e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 332937
Homologene: 2422
Igkv4-92
Name: immunoglobulin kappa variable 4-92
Synonyms: IgVk ay4, LOC384410
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 384410
Large
Name:
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 133,633,789 bp
  • T to A, chromosome 1 at 134,588,746 bp
  • T to A, chromosome 1 at 161,198,231 bp
  • T to C, chromosome 1 at 166,483,982 bp
  • T to C, chromosome 1 at 184,033,506 bp
  • A to G, chromosome 2 at 28,559,423 bp
  • A to T, chromosome 2 at 89,751,895 bp
  • A to T, chromosome 2 at 150,255,490 bp
  • A to T, chromosome 2 at 165,353,670 bp
  • T to A, chromosome 2 at 180,202,220 bp
  • A to T, chromosome 3 at 30,684,890 bp
  • G to T, chromosome 3 at 32,955,831 bp
  • T to C, chromosome 3 at 38,455,803 bp
  • C to T, chromosome 3 at 69,092,809 bp
  • T to C, chromosome 3 at 95,585,220 bp
  • T to C, chromosome 3 at 108,398,659 bp
  • C to T, chromosome 3 at 142,304,365 bp
  • A to T, chromosome 3 at 144,954,946 bp
  • G to T, chromosome 4 at 57,855,912 bp
  • G to T, chromosome 4 at 88,868,271 bp
  • A to G, chromosome 4 at 115,489,960 bp
  • G to T, chromosome 4 at 126,720,544 bp
  • T to G, chromosome 4 at 143,419,009 bp
  • T to A, chromosome 4 at 154,882,324 bp
  • G to A, chromosome 5 at 24,430,127 bp
  • T to C, chromosome 5 at 92,303,934 bp
  • T to A, chromosome 5 at 110,101,363 bp
  • C to T, chromosome 5 at 151,062,767 bp
  • A to T, chromosome 6 at 68,755,554 bp
  • T to C, chromosome 6 at 91,773,916 bp
  • A to G, chromosome 6 at 116,413,786 bp
  • T to C, chromosome 6 at 121,383,919 bp
  • T to A, chromosome 7 at 16,747,323 bp
  • A to T, chromosome 7 at 80,923,064 bp
  • A to G, chromosome 7 at 89,407,501 bp
  • T to C, chromosome 7 at 127,374,394 bp
  • T to A, chromosome 7 at 133,651,044 bp
  • G to T, chromosome 8 at 10,476,114 bp
  • G to T, chromosome 8 at 70,452,718 bp
  • T to G, chromosome 8 at 72,818,096 bp
  • T to C, chromosome 8 at 105,463,898 bp
  • T to C, chromosome 9 at 3,000,937 bp
  • T to A, chromosome 9 at 70,766,074 bp
  • C to T, chromosome 9 at 91,384,152 bp
  • A to T, chromosome 9 at 106,932,997 bp
  • T to G, chromosome 9 at 110,098,795 bp
  • A to G, chromosome 9 at 123,577,025 bp
  • T to A, chromosome 10 at 52,543,022 bp
  • A to G, chromosome 10 at 76,147,594 bp
  • T to C, chromosome 10 at 89,789,355 bp
  • T to C, chromosome 10 at 91,060,094 bp
  • T to C, chromosome 10 at 100,088,222 bp
  • A to T, chromosome 11 at 6,224,245 bp
  • A to T, chromosome 11 at 59,129,653 bp
  • AGCGGTCGTAGGC to AGC, chromosome 11 at 73,395,654 bp
  • G to A, chromosome 11 at 79,527,451 bp
  • C to T, chromosome 11 at 105,857,553 bp
  • G to T, chromosome 11 at 118,264,905 bp
  • C to T, chromosome 12 at 8,010,086 bp
  • G to C, chromosome 12 at 81,377,830 bp
  • A to T, chromosome 12 at 113,574,462 bp
  • T to A, chromosome 12 at 116,427,786 bp
  • A to G, chromosome 13 at 9,170,737 bp
  • G to T, chromosome 13 at 11,662,130 bp
  • A to T, chromosome 13 at 27,579,819 bp
  • A to G, chromosome 13 at 33,880,097 bp
  • A to G, chromosome 13 at 41,102,959 bp
  • A to G, chromosome 13 at 93,627,323 bp
  • A to T, chromosome 13 at 100,179,440 bp
  • T to A, chromosome 14 at 26,770,477 bp
  • C to T, chromosome 14 at 47,399,665 bp
  • T to C, chromosome 14 at 52,463,854 bp
  • A to G, chromosome 15 at 65,883,830 bp
  • G to T, chromosome 15 at 71,799,337 bp
  • T to A, chromosome 15 at 101,627,768 bp
  • A to T, chromosome 16 at 21,956,165 bp
  • T to A, chromosome 17 at 34,243,516 bp
  • T to A, chromosome 17 at 78,866,345 bp
  • A to G, chromosome 18 at 47,291,172 bp
  • T to A, chromosome 19 at 6,320,618 bp
  • A to C, chromosome 19 at 40,554,817 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5135 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
043261-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.