Strain Name:
C57BL/6J-MtgxR5860Btlr/Mmmh
Stock Number:
044072-MU
Citation ID:
RRID:MMRRC_044072-MU
Other Names:
R5860 (G1)
Major Collection:

Strain Information

Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, DD7A5-7, TM7LN3, EGF-TM7, Ly71, Emr1
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Ptprf
Name: protein tyrosine phosphatase receptor type F
Synonyms: LAR, RPTP-LAR
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19268
HGNC: HGNC:9670
Homologene: 20623
Tet1
Name: tet methylcytosine dioxygenase 1
Synonyms: 2510010B09Rik, D10Ertd17e, Cxxc6, BB001228
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 52463
Homologene: 12735
Crybg3
Name: beta-gamma crystallin domain containing 3
Synonyms: Gm9581
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 224273
Homologene: 28544
Tpgs1
Name: tubulin polyglutamylase complex subunit 1
Synonyms: Gtrgeo22, Gm16517
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 110012
VEGA: 10
Homologene: 17525
Trim13
Name: tripartite motif-containing 13
Synonyms: 3110001L12Rik, LEU5, Rfp2, RNF77
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 66597
VEGA: 14
HGNC: HGNC:9976
Homologene: 4234
Ylpm1
Name: YLP motif containing 1
Synonyms: ZAP, Zap3, A930013E17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56531
Homologene: 87707
Cdyl
Name: chromodomain protein, Y chromosome-like
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 12593
VEGA: 13
HGNC: HGNC:1811
Homologene: 3548
Atf6
Name: activating transcription factor 6
Synonyms: ESTM49, 9130025P16Rik, Atf6alpha
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 226641
HGNC: HGNC:791
Homologene: 32015
Golga4
Name: golgin A4
Synonyms: golgin-245, Olp-1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 54214
HGNC: HGNC:4427
Homologene: 68224
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Fnbp4
Name: formin binding protein 4
Synonyms: FBP30
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 55935
Homologene: 9087
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 6030449K19Rik, 2900036C23Rik, 2410152H17Rik, 2810413I22Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66315
Homologene: 10778
Lgr4
Name: leucine-rich repeat-containing G protein-coupled receptor 4
Synonyms: A930009A08Rik, Gpr48, A330106J01Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 107515
Homologene: 10226
Gtpbp4
Name: GTP binding protein 4
Synonyms: 2610028C09Rik, Crfg, Nog1
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 69237
VEGA: 13
Homologene: 7100
Mbd1
Name: methyl-CpG binding domain protein 1
Synonyms: PCM1, Cxxc3
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 17190
VEGA: 18
HGNC: HGNC:6916
Homologene: 8414
Rapsn
Name: receptor-associated protein of the synapse
Synonyms: rapsyn, Raps, 43kDa acetylcholine receptor-associated protein, Nraps
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 19400
HGNC: HGNC:9863
Homologene: 3708
Ccnk
Name: cyclin K
Synonyms: CPR4, CycK
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12454
VEGA: 12
HGNC: HGNC:1596
Homologene: 14748
Actr8
Name: ARP8 actin-related protein 8
Synonyms: ARP8, 5730542K05Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 56249
VEGA: 14
Homologene: 11286
Ric1
Name: RAB6A GEF complex partner 1
Synonyms: C130057E09Rik, C030046E11Rik
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 226089
Homologene: 13806
Dynlt2b
Name: dynein light chain Tctex-type 2B
Synonyms: 2410011K15Rik, 0610012D17Rik, Tctex1d2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 66061
Homologene: 41625
Exosc8
Name: exosome component 8
Synonyms: 2310032N20Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 69639
Homologene: 12323
Creb3l1
Name: cAMP responsive element binding protein 3-like 1
Synonyms: BBF-2 (drosophila) homolog, Oasis
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 26427
Homologene: 8058
Bach2
Name: BTB and CNC homology, basic leucine zipper transcription factor 2
Synonyms: E030004N02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 12014
Homologene: 7240
Cthrc1
Name: collagen triple helix repeat containing 1
Synonyms: 1110014B07Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 68588
Homologene: 16320
Fat1
Name: FAT atypical cadherin 1
Synonyms: mFat1, 2310038E12Rik, Fath
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 14107
HGNC: HGNC:3595
Homologene: 66302
M1ap
Name: meiosis 1 associated protein
Synonyms: D6Mm5e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110958
Homologene: 13210
Zftraf1
Name: zinc finger TRAF type containing 1
Synonyms: Chrp, 1110031M01Rik, Cyhr1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 54151
Homologene: 32791
Marchf7
Name: membrane associated ring-CH-type finger 7
Synonyms: Axot, Gtrgeo17, March7
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 57438
Homologene: 10753
Mtus1
Name: mitochondrial tumor suppressor 1
Synonyms: MD44, MTSG1, Atip1, B430305I03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 102103
Homologene: 100292
Rnft2
Name: ring finger protein, transmembrane 2
Synonyms: B830028P19Rik, Tmem118
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269695
Homologene: 41892
Smg5
Name: SMG5 nonsense mediated mRNA decay factor
Synonyms: Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 229512
Homologene: 9095
B3gat2
Name: beta-1,3-glucuronyltransferase 2
Synonyms: GlcAT-S
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 280645
HGNC: HGNC:922
Homologene: 50574
Dock2
Name: dedicator of cyto-kinesis 2
Synonyms: MBC, CED-5, Hch
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 94176
HGNC: HGNC:2988
Homologene: 37984
Insc
Name: INSC spindle orientation adaptor protein
Synonyms: Inscuteable, 3830422K02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233752
Homologene: 78662
Dchs1
Name: dachsous cadherin related 1
Synonyms: C130033F22Rik, 3110041P15Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 233651
Homologene: 2771
Col11a2
Name: collagen, type XI, alpha 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 12815
HGNC: HGNC:2187
Homologene: 22547
Xpr1
Name: xenotropic and polytropic retrovirus receptor 1
Synonyms: suppressor of yeast Ga deletion, Syg1, Rmc-1, Rmc1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 19775
Homologene: 134226
Cryga
Name: crystallin, gamma A
Synonyms: DGcry-4, Cryg-4, Secc
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12964
HGNC: HGNC:2408
Homologene: 129704
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Oas1e
Name: 2'-5' oligoadenylate synthetase 1E
Synonyms: 2'-5' oligoadenylate synthetase-like 7
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231699
HGNC: HGNC:8086
Homologene: 110815
Nek11
Name: NIMA (never in mitosis gene a)-related expressed kinase 11
Synonyms: 4932416N14Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 208583
Homologene: 57008
A2ml1
Name: alpha-2-macroglobulin like 1
Synonyms: Ovos2, BC048546
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232400
Homologene: 45969
Serpinh1
Name: serine (or cysteine) peptidase inhibitor, clade H, member 1
Synonyms: gp46, colligin, J6, Hsp47, Cbp2, Cbp1, Serpinh2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 12406
HGNC: HGNC:1546
Homologene: 20331
Chi3l1
Name: chitinase 3 like 1
Synonyms: Brp39, Gp39, Chil1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12654
HGNC: HGNC:1932
Homologene: 55569
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, 4732458A06Rik, D130016K21Rik, 9430063L05Rik, Usmg4
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Tmed6
Name: transmembrane p24 trafficking protein 6
Synonyms: 1810018I24Rik, 1810015P03Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66269
Homologene: 11938
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 194357
Homologene: 77226
Ogfr
Name: opioid growth factor receptor
Synonyms: 2010013E17Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 72075
Homologene: 7199
Cyp2c39
Name: cytochrome P450, family 2, subfamily c, polypeptide 39
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 13098
Homologene: 117948
Dhx30
Name: DExH-box helicase 30
Synonyms: Ddx30, 2810477H02Rik, C130058C04Rik, helG, DEAH (Asp-Glu-Ala-His) box polypeptide 30
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 72831
Homologene: 15779
Glyctk
Name: glycerate kinase
Synonyms: 6230410P16Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235582
Homologene: 14738
Adamts1
Name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Synonyms: ADAM-TS1, METH1, METH-1, ADAMTS-1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 11504
HGNC: HGNC:217
Homologene: 21381
Notch4
Name: notch 4
Synonyms: Int-3, Int3, N4
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18132
HGNC: HGNC:7884
Homologene: 3351
Nsd3
Name: nuclear receptor binding SET domain protein 3
Synonyms: WHISTLE, Whsc1l1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234135
Homologene: 56960
Prex1
Name: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Synonyms: P-REX1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277360
Homologene: 10821
Or8g20
Name: olfactory receptor family 8 subfamily G member 20
Synonyms: IB3, MOR171-5, GA_x6K02T2PVTD-33181773-33180838, Olfr44
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18343
VEGA: 9
HGNC: HGNC:8484
Homologene: 133633
Cnppd1
Name: cyclin Pas1/PHO80 domain containing 1
Synonyms: 1810031K17Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 69171
Homologene: 9238
Zscan29
Name: zinc finger SCAN domains 29
Synonyms: Zfp690
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 99334
Homologene: 17586
Dsc1
Name: desmocollin 1
Synonyms: Dsc1b, Dsc1a
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 13505
VEGA: 18
HGNC: HGNC:3035
Homologene: 22761
Slc5a12
Name: solute carrier family 5 (sodium/glucose cotransporter), member 12
Synonyms: SMCT2
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241612
Homologene: 15107
Tas2r109
Name: taste receptor, type 2, member 109
Synonyms: T2R09, Tas2r9, mGR09, mt2r62
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387343
Homologene: 87292
Or2y15
Name: olfactory receptor family 2 subfamily Y member 15
Synonyms: GA_x6K02T2QP88-5975166-5974231, MOR256-22, Olfr1387
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258465
Homologene: 74034
Mrgpra6
Name: MAS-related GPR, member A6
Synonyms: MrgA6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 381886
Speer4b
Name: spermatogenesis associated glutamate (E)-rich protein 4B
Synonyms: SPEER-4B, 1700081O22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 73526
Homologene: 69402
Gm14149
Name: predicted gene 14149
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 100038513
4930568A12Rik
Name: RIKEN cDNA 4930568A12 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 75883
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 23,815,319 bp
  • A to G, chromosome 1 at 34,485,580 bp
  • T to C, chromosome 1 at 65,103,368 bp
  • A to G, chromosome 1 at 75,136,487 bp
  • A to G, chromosome 1 at 134,185,171 bp
  • T to C, chromosome 1 at 155,332,122 bp
  • A to T, chromosome 1 at 170,841,775 bp
  • G to A, chromosome 1 at 170,841,776 bp
  • T to C, chromosome 2 at 60,236,843 bp
  • T to A, chromosome 2 at 90,757,482 bp
  • T to C, chromosome 2 at 91,045,514 bp
  • T to C, chromosome 2 at 92,024,054 bp
  • G to A, chromosome 2 at 109,991,151 bp
  • C to A, chromosome 2 at 110,597,624 bp
  • G to T, chromosome 2 at 121,164,037 bp
  • C to A, chromosome 2 at 151,224,305 bp
  • G to A, chromosome 2 at 166,644,684 bp
  • T to C, chromosome 2 at 180,592,492 bp
  • C to T, chromosome 3 at 54,735,042 bp
  • T to A, chromosome 3 at 88,342,907 bp
  • A to G, chromosome 3 at 97,724,188 bp
  • A to G, chromosome 4 at 32,580,268 bp
  • T to C, chromosome 4 at 118,211,289 bp
  • T to C, chromosome 5 at 27,500,228 bp
  • A to G, chromosome 5 at 118,228,803 bp
  • A to T, chromosome 5 at 120,791,950 bp
  • T to A, chromosome 6 at 40,880,407 bp
  • T to A, chromosome 6 at 83,003,814 bp
  • A to G, chromosome 6 at 125,643,090 bp
  • G to T, chromosome 6 at 125,679,265 bp
  • T to C, chromosome 6 at 128,541,061 bp
  • T to C, chromosome 6 at 132,980,701 bp
  • T to C, chromosome 7 at 47,189,351 bp
  • G to A, chromosome 7 at 99,346,364 bp
  • C to T, chromosome 7 at 105,772,035 bp
  • A to C, chromosome 7 at 114,791,148 bp
  • C to A, chromosome 8 at 25,666,091 bp
  • T to G, chromosome 8 at 41,076,266 bp
  • C to T, chromosome 8 at 45,051,129 bp
  • G to T, chromosome 8 at 107,064,154 bp
  • T to A, chromosome 9 at 39,484,471 bp
  • A to G, chromosome 9 at 105,392,961 bp
  • T to C, chromosome 9 at 106,155,707 bp
  • G to A, chromosome 9 at 110,084,577 bp
  • T to C, chromosome 9 at 118,558,106 bp
  • A to G, chromosome 10 at 62,812,620 bp
  • G to A, chromosome 10 at 79,669,711 bp
  • C to T, chromosome 11 at 34,256,562 bp
  • A to G, chromosome 11 at 49,459,736 bp
  • C to T, chromosome 12 at 85,040,886 bp
  • A to T, chromosome 12 at 108,187,207 bp
  • A to T, chromosome 13 at 8,973,160 bp
  • A to C, chromosome 13 at 35,858,083 bp
  • T to A, chromosome 14 at 7,931,135 bp
  • T to A, chromosome 14 at 29,986,285 bp
  • T to G, chromosome 14 at 61,604,739 bp
  • T to C, chromosome 15 at 39,086,685 bp
  • A to T, chromosome 15 at 76,648,191 bp
  • T to C, chromosome 15 at 76,656,415 bp
  • A to G, chromosome 16 at 32,428,796 bp
  • C to A, chromosome 16 at 56,155,359 bp
  • A to C, chromosome 16 at 59,565,269 bp
  • A to G, chromosome 16 at 85,798,544 bp
  • C to A, chromosome 17 at 34,064,185 bp
  • G to T, chromosome 17 at 34,582,418 bp
  • T to A, chromosome 17 at 57,445,034 bp
  • T to C, chromosome 18 at 20,095,024 bp
  • C to A, chromosome 18 at 74,276,697 bp
  • A to G, chromosome 19 at 29,599,845 bp
  • A to T, chromosome 19 at 39,536,826 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R5860 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044072-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.