Strain Name:
C57BL/6J-MtgxR6864Btlr/Mmmh
Stock Number:
044964-MU
Citation ID:
RRID:MMRRC_044964-MU
Other Names:
R6864 (G1)
Major Collection:

Strain Information

Prkacb
Name: protein kinase, cAMP dependent, catalytic, beta
Synonyms: cAMP-dependent protein kinase C beta, Pkacb
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 18749
HGNC: HGNC:9381
Homologene: 121718
Bmp7
Name: bone morphogenetic protein 7
Synonyms: OP1, osteogenic protein 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12162
HGNC: HGNC:1074
Homologene: 20410
Adgre1
Name: adhesion G protein-coupled receptor E1
Synonyms: F4/80, TM7LN3, EGF-TM7, Emr1, Ly71, DD7A5-7
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 13733
VEGA: 17
HGNC: HGNC:3336
Homologene: 1493
Prss12
Name: serine protease 12 neurotrypsin (motopsin)
Synonyms: motopsin, Bssp-3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19142
HGNC: HGNC:9477
Homologene: 7490
Cradd
Name: CASP2 and RIPK1 domain containing adaptor with death domain
Synonyms: RAIDD
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 12905
VEGA: 10
HGNC: HGNC:2340
Homologene: 2821
Rai14
Name: retinoic acid induced 14
Synonyms: 1700008J19Rik, 1700020L11Rik, Ankycorbin, Norpeg
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 75646
VEGA: 15
Homologene: 9199
Oxr1
Name: oxidation resistance 1
Synonyms: C7B, 2210416C20Rik, C7
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 170719
VEGA: 15
Homologene: 24993
Tns3
Name: tensin 3
Synonyms: Tens1, F830010I22Rik, TEM6
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 319939
Homologene: 49713
Flnb
Name: filamin, beta
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Trappc9
Name: trafficking protein particle complex 9
Synonyms: 2900005P22Rik, Nibp, 4632408O18Rik, TRS130, 1810044A24Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76510
VEGA: 15
Homologene: 81931
Anln
Name: anillin, actin binding protein
Synonyms: 2900037I21Rik, 1110037A17Rik, Scraps
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 68743
VEGA: 9
Homologene: 41281
Atxn2
Name: ataxin 2
Synonyms: 9630045M23Rik, Sca2, ATX2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20239
Homologene: 2234
Tasor
Name: transcription activation suppressor
Synonyms: 4933409E02Rik, MommeD6, Fam208a, D14Abb1e
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218850
VEGA: 14
Homologene: 9062
Dock4
Name: dedicator of cytokinesis 4
Synonyms: 6330411N01Rik, EST N28122
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238130
VEGA: 12
Homologene: 56680
Ccnk
Name: cyclin K
Synonyms: CycK, CPR4
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 12454
VEGA: 12
HGNC: HGNC:1596
Homologene: 14748
Mcm3ap
Name: minichromosome maintenance complex component 3 associated protein
Synonyms: GANP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 54387
VEGA: 10
HGNC: HGNC:6946
Homologene: 2902
Bcl2
Name: B cell leukemia/lymphoma 2
Synonyms: C430015F12Rik, Bcl-2, D830018M01Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 12043
HGNC: HGNC:990
Homologene: 527
Peg3
Name: paternally expressed 3
Synonyms: End4, Pw1, Zfp102, Gcap4
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18616
HGNC: HGNC:8826
Homologene: 31363
Calr
Name: calreticulin
Synonyms: Calregulin, CRT
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 12317
HGNC: HGNC:1455
Homologene: 37911
Anxa6
Name: annexin A6
Synonyms: Cabm, AnxVI, Anx6, Camb, Annexin VI
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11749
HGNC: HGNC:544
Homologene: 55558
Eml2
Name: echinoderm microtubule associated protein like 2
Synonyms: 1600029N02Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72205
Homologene: 8125
AU040320
Name: expressed sequence AU040320
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100317
Homologene: 11764
Lcorl
Name: ligand dependent nuclear receptor corepressor-like
Synonyms: Gm3414, A830039H10Rik, Mlr1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100041576
Homologene: 82325
Stk32b
Name: serine/threonine kinase 32B
Synonyms: 2510009F08Rik, YANK2, Stk32, STKG6
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 64293
Homologene: 48654
Kel
Name: Kell blood group
Synonyms: CD238
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 23925
HGNC: HGNC:6308
Homologene: 362
Kbtbd2
Name: kelch repeat and BTB (POZ) domain containing 2
Synonyms: Bklhd1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 210973
Homologene: 17122
Muc5ac
Name: mucin 5, subtypes A and C, tracheobronchial/gastric
Synonyms: MGM, 2210005L13Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 17833
HGNC: HGNC:7515
Homologene: 137237
Camta2
Name: calmodulin binding transcription activator 2
Synonyms: Kiaa0909-hp
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216874
Homologene: 9021
Zfp831
Name: zinc finger protein 831
Synonyms: OTTMUSG00000017459, ENSMUSG00000050600
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100043757
Homologene: 19013
Plekhh2
Name: pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213556
VEGA: 17
Homologene: 35317
Slc35f4
Name: solute carrier family 35, member F4
Synonyms: 4930550L21Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75288
Homologene: 45939
Zfp943
Name: zinc finger prtoein 943
Synonyms: 4930432O21Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74670
Homologene: 134342
Dym
Name: dymeclin
Synonyms: C030019K18Rik, 1810041M12Rik, 4933427L07Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 69190
VEGA: 18
Homologene: 69237
Tmem175
Name: transmembrane protein 175
Synonyms: 3010001K23Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 72392
Homologene: 12461
Slc2a2
Name: solute carrier family 2 (facilitated glucose transporter), member 2
Synonyms: Glut2, Glut-2, liver-type glucose transporter
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 20526
Homologene: 68047
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Prkch
Name: protein kinase C, eta
Synonyms: Pkch
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 18755
HGNC: HGNC:9403
Homologene: 84384
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Trim28
Name: tripartite motif-containing 28
Synonyms: Tif1b, MommeD9, KRIP-1, KAP-1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 21849
Homologene: 21175
Or1j11
Name: olfactory receptor family 1 subfamily E member 1
Synonyms: GA_x6K02T2NLDC-33116096-33117025, Olfr339, MOR136-3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258951
Homologene: 133615
Mylk
Name: myosin, light polypeptide kinase
Synonyms: telokin, Mlck, nmMlck, A930019C19Rik, 9530072E15Rik, MLCK210, MLCK108
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Or2y17
Name: olfactory receptor family 2 subfamily Y member 17
Synonyms: GA_x6K02T2QP88-6094111-6093176, MOR256-2, Olfr1390
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 259068
Dcaf7
Name: DDB1 and CUL4 associated factor 7
Synonyms: Wdr68, 2610037L01Rik, 1700012F10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 71833
Homologene: 55930
Zfp536
Name: zinc finger protein 536
Synonyms: 9630010P11Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243937
Homologene: 8813
Vmn1r210
Name: vomeronasal 1 receptor 210
Synonyms: V1rh10
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171269
Homologene: 110880
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Schnurri-3, E030045D18Rik, 2900056N03Rik, Shn3, Krc
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Vmn2r24
Name: vomeronasal 2, receptor 24
Synonyms: EG243628
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243628
Homologene: 135915
Ms4a1
Name: membrane-spanning 4-domains, subfamily A, member 1
Synonyms: Cd20, Ly-44
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12482
HGNC: HGNC:7315
Homologene: 7259
Or4f52
Name: olfactory receptor family 4 subfamily F member 52
Synonyms: Olfr1275, GA_x6K02T2Q125-72283260-72282322, MOR245-18
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 257980
Homologene: 79419
Tktl2
Name: transketolase-like 2
Synonyms: 4933401I19Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 74419
Homologene: 69456
Parp12
Name: poly (ADP-ribose) polymerase family, member 12
Synonyms: Zc3hdc1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 243771
Homologene: 11236
Defb30
Name: defensin beta 30
Synonyms: 2410125J01Rik, 4930449O14Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 73670
Homologene: 86862
Or4d10b
Name: olfactory receptor family 4 subfamily D member 10B
Synonyms: MOR239-2, GA_x6K02T2RE5P-2418550-2417609, Olfr1424
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258676
Homologene: 82294
Slc22a6
Name: solute carrier family 22 (organic anion transporter), member 6
Synonyms: NKT, mOat1, Oat1, Orctl1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 18399
VEGA: 19
Homologene: 16813
Or2y16
Name: olfactory receptor family 2 subfamily Y member 16
Synonyms: GA_x6K02T2QP88-5991012-5990077, MOR256-28, Olfr1388
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 258459
Homologene: 74258
Eef1a2
Name: eukaryotic translation elongation factor 1 alpha 2
Synonyms: Eef1a, S1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 13628
HGNC: HGNC:3192
Homologene: 121568
Mbd3l2
Name: methyl-CpG binding domain protein 3-like 2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 234988
VEGA: 9
Homologene: 44896
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 106,543,281 bp
  • T to A, chromosome 2 at 36,421,820 bp
  • C to T, chromosome 2 at 111,231,197 bp
  • A to G, chromosome 2 at 172,940,062 bp
  • C to A, chromosome 2 at 174,646,740 bp
  • T to C, chromosome 2 at 181,149,684 bp
  • T to A, chromosome 3 at 28,721,725 bp
  • C to A, chromosome 3 at 123,447,384 bp
  • T to C, chromosome 3 at 146,745,378 bp
  • T to C, chromosome 4 at 85,096,792 bp
  • C to A, chromosome 4 at 120,094,888 bp
  • T to A, chromosome 4 at 126,847,819 bp
  • A to T, chromosome 5 at 37,448,805 bp
  • T to A, chromosome 5 at 45,747,204 bp
  • A to C, chromosome 5 at 108,645,979 bp
  • C to T, chromosome 5 at 121,779,494 bp
  • T to A, chromosome 6 at 3,374,750 bp
  • T to C, chromosome 6 at 39,111,736 bp
  • A to G, chromosome 6 at 41,703,760 bp
  • T to A, chromosome 6 at 56,780,026 bp
  • A to T, chromosome 6 at 123,779,158 bp
  • T to C, chromosome 7 at 6,712,762 bp
  • T to A, chromosome 7 at 13,029,458 bp
  • T to C, chromosome 7 at 19,196,281 bp
  • A to G, chromosome 7 at 37,568,515 bp
  • C to T, chromosome 7 at 141,809,744 bp
  • T to C, chromosome 8 at 66,512,339 bp
  • A to T, chromosome 8 at 84,844,928 bp
  • A to G, chromosome 9 at 18,443,499 bp
  • A to T, chromosome 9 at 22,382,249 bp
  • A to G, chromosome 10 at 76,507,479 bp
  • T to C, chromosome 10 at 95,175,927 bp
  • C to T, chromosome 10 at 107,827,806 bp
  • A to G, chromosome 11 at 8,493,196 bp
  • A to T, chromosome 11 at 49,340,753 bp
  • G to T, chromosome 11 at 49,443,940 bp
  • T to C, chromosome 11 at 54,986,185 bp
  • T to A, chromosome 11 at 70,671,966 bp
  • C to T, chromosome 11 at 106,046,821 bp
  • T to A, chromosome 12 at 40,745,746 bp
  • A to G, chromosome 12 at 73,759,617 bp
  • G to A, chromosome 12 at 108,202,214 bp
  • T to A, chromosome 13 at 22,827,543 bp
  • C to T, chromosome 14 at 7,905,640 bp
  • T to A, chromosome 14 at 27,461,158 bp
  • T to C, chromosome 14 at 49,318,853 bp
  • T to A, chromosome 14 at 63,036,103 bp
  • G to T, chromosome 15 at 10,633,168 bp
  • T to G, chromosome 15 at 41,823,387 bp
  • A to T, chromosome 15 at 72,937,162 bp
  • C to A, chromosome 16 at 34,874,150 bp
  • T to A, chromosome 17 at 21,992,612 bp
  • C to T, chromosome 17 at 57,478,879 bp
  • T to C, chromosome 17 at 84,617,999 bp
  • T to A, chromosome 18 at 75,056,738 bp
  • G to T, chromosome 19 at 8,618,441 bp
  • C to A, chromosome 19 at 11,253,178 bp
  • A to T, chromosome 19 at 12,059,413 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R6864 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
044964-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.