Strain Name:
C57BL/6J-MtgxR7113Btlr/Mmmh
Stock Number:
045205-MU
Citation ID:
RRID:MMRRC_045205-MU
Other Names:
R7113 (G1)
Major Collection:

Strain Information

Jmjd1c
Name: jumonji domain containing 1C
Synonyms: TRIP8, D630035I23Rik, 5430433L24Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 108829
Homologene: 3129
Zfand6
Name: zinc finger, AN1-type domain 6
Synonyms: 3110005P07Rik, Za20d3, Awp1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 65098
Homologene: 10372
Med13l
Name: mediator complex subunit 13-like
Synonyms: 9030618F05Rik, Trap240L, Thrap2, 6330591G05Rik, 2210413I17Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 76199
Homologene: 25256
Herc2
Name: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms: D7H15F37S1, D7H15F32S1, rjs, jdf2, D15F32S1h
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 15204
HGNC: HGNC:4868
Homologene: 3430
Plcg1
Name: phospholipase C, gamma 1
Synonyms: Plc-gamma1, Cded, Plc-1, Plcg-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 18803
HGNC: HGNC:9065
Homologene: 1997
Rad17
Name: RAD17 checkpoint clamp loader component
Synonyms: 9430035O09Rik, MmRad24
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 19356
VEGA: 13
HGNC: HGNC:9807
Homologene: 32117
Cic
Name: capicua transcriptional repressor
Synonyms: 1200010B10Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 71722
Homologene: 87637
Apob
Name: apolipoprotein B
Synonyms: apob-48, apob-100
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 238055
HGNC: HGNC:603
Homologene: 328
Ppp1r2
Name: protein phosphatase 1, regulatory inhibitor subunit 2
Synonyms: 0610025N14Rik, 4930440J04Rik, 5430408E15Rik, 2310007G06Rik, I-2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 66849
Homologene: 4546
Triml2
Name: tripartite motif family-like 2
Synonyms: EG622117
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 622117
Homologene: 18316
Ptprs
Name: protein tyrosine phosphatase receptor type S
Synonyms: PTP-NU3, Ptpt9, RPTPsigma, PTPsigma
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 19280
HGNC: HGNC:9681
Homologene: 20626
Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
Synonyms: Dnchc2, m152Asp, m407Asp, b2b414Clo, D030010H02Rik, D330044F14Rik, 4432416O06Rik, DHC1b, DHC2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 110350
HGNC: HGNC:2962
Homologene: 14468
Zfp236
Name: zinc finger protein 236
Synonyms: LOC240456
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 329002
Homologene: 7198
Pias4
Name: protein inhibitor of activated STAT 4
Synonyms: PIASy
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 59004
Homologene: 104136
Lonrf1
Name: LON peptidase N-terminal domain and ring finger 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244421
Homologene: 34980
Trpm2
Name: transient receptor potential cation channel, subfamily M, member 2
Synonyms: TRPC7, Trrp7, 9830168K16Rik, LTRPC2
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 28240
Homologene: 20709
Adamts6
Name: ADAM metallopeptidase with thrombospondin type 1 motif 6
Synonyms: b2b2182Clo, b2b2187.1Clo, ADAM-TS6, b2b1879.1Clo, A930019D11Rik, b2b2029Clo, b2b2228Clo
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 108154
VEGA: 13
HGNC: HGNC:222
Homologene: 82573
Ceacam18
Name: CEA cell adhesion molecule 18
Synonyms: 2010110O04Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 72431
Homologene: 48111
Or8g52
Name: olfactory receptor family 8 subfamily G member 52
Synonyms: GA_x6K02T2PVTD-33416730-33417668, Olfr965, MOR171-28
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258165
VEGA: 9
Vwf
Name: Von Willebrand factor
Synonyms: B130011O06Rik, 6820430P06Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 22371
Homologene: 466
Kif9
Name: kinesin family member 9
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 16578
Homologene: 65620
Lrrc37
Name: leucine rich repeat containing 37
Synonyms: Gm884, LOC380730
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380730
Homologene: 134511
Stpg2
Name: sperm tail PG rich repeat containing 2
Synonyms: LOC381476, B930007M17Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 381476
Homologene: 52167
Tdpoz1
Name: TD and POZ domain containing 1
Synonyms: Spopl1, 2cpoz56
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 207213
Homologene: 128308
S100pbp
Name: S100P binding protein
Synonyms: 4930429A08Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 74648
Homologene: 81892
Kcnma1
Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Synonyms: 5730414M22Rik, Slo, MaxiK, BKCa, BK channel alpha subunit, mSlo1, Slo1
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 16531
HGNC: HGNC:6284
Homologene: 1693
Scarf1
Name: scavenger receptor class F, member 1
Synonyms: SREC, SREC-I
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 380713
Homologene: 2741
Vmn2r72
Name: vomeronasal 2, receptor 72
Synonyms: EG244114, Vmn2r72-ps
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 244114
Homologene: 115466
Manea
Name: mannosidase, endo-alpha
Synonyms: 4932703L02Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 242362
Homologene: 11636
Kcnv2
Name: potassium channel, subfamily V, member 2
Synonyms: KV11.1
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 240595
Homologene: 26423
Cntln
Name: centlein, centrosomal protein
Synonyms: B430108F07Rik, D530005L17Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 338349
Homologene: 9805
Plcl2
Name: phospholipase C-like 2
Synonyms: Plce2, PRIP-2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224860
VEGA: 17
HGNC: HGNC:9064
Homologene: 9052
Pik3cg
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Synonyms: PI3Kgamma, PI3Kgamma, p110gamma, 5830428L06Rik, PI(3)Kgamma
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 30955
HGNC: HGNC:8978
Homologene: 68269
Upk1a
Name: uroplakin 1A
Synonyms: Tspan21, 1110031P12Rik, Upk1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 109637
Homologene: 21383
Cyp2d26
Name: cytochrome P450, family 2, subfamily d, polypeptide 26
Synonyms: 1300006E06Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 76279
VEGA: 15
Homologene: 130660
Unc5c
Name: unc-5 netrin receptor C
Synonyms: B130051O18Rik, Unc5h3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 22253
Homologene: 2765
Vmn2r54
Name: vomeronasal 2, receptor 54
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 666085
Homologene: 104040
Nxph3
Name: neurexophilin 3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 104079
HGNC: HGNC:8077
Homologene: 5227
Ccdc157
Name: coiled-coil domain containing 157
Synonyms: 4930562D19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 216516
Homologene: 72271
Adarb2
Name: adenosine deaminase, RNA-specific, B2
Synonyms: RED2, Adar3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 94191
HGNC: HGNC:227
Homologene: 10276
Hivep3
Name: human immunodeficiency virus type I enhancer binding protein 3
Synonyms: Shn3, E030045D18Rik, Krc, 2900056N03Rik, Schnurri-3
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 16656
Homologene: 7803
Ano7
Name: anoctamin 7
Synonyms: Pcanap5, NGEP-L, IPCA-5, NGEP, Tmem16g
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 404545
Homologene: 45787
Rtp3
Name: receptor transporter protein 3
Synonyms: Tmem7
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235636
Homologene: 135957
Ehd3
Name: EH-domain containing 3
Synonyms: Ehd2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 57440
HGNC: HGNC:3244
Homologene: 81837
Slc30a9
Name: solute carrier family 30 (zinc transporter), member 9
Synonyms: 2310024J23Rik, GAC63
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 109108
HGNC: HGNC:1329
Homologene: 4627
Mas1
Name: MAS1 oncogene
Synonyms: Mas receptor, Mas-1, MasR
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 17171
HGNC: HGNC:6899
Homologene: 1782
Or1l4
Name: olfactory receptor family 1 subfamily L member 4
Synonyms: MOR138-1, Olfr365, GA_x6K02T2NLDC-33885305-33886243
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258656
Homologene: 74156
Gpt2
Name: glutamic pyruvate transaminase (alanine aminotransferase) 2
Synonyms: ALT2, 4631422C05Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 108682
Homologene: 68832
Chil4
Name: chitinase-like 4
Synonyms: Chi3l4, Ym2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 104183
Homologene: 74931
Il19
Name: interleukin 19
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329244
HGNC: HGNC:5990
Homologene: 17813
Speer1c
Name: spermatogenesis associated glutamate (E)-rich protein 1C
Synonyms: Gm5152
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 381612
Podxl
Name: podocalyxin-like
Synonyms: podocalyxin, Podxl1, Pclp1, Ly102, PC
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 27205
HGNC: HGNC:9171
Homologene: 137260
Rpl35
Name: ribosomal protein L35
Synonyms: 2410039E09Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66489
Homologene: 31432
Rdh8
Name: retinol dehydrogenase 8
Synonyms: LOC235033, prRDH
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 235033
VEGA: 9
Homologene: 41062
Vstm2l
Name: V-set and transmembrane domain containing 2-like
Synonyms: LOC277432
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 277432
Homologene: 15414
Pcdha5
Name: protocadherin alpha 5
Synonyms: Crnr6, Cnr6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 12941
HGNC: HGNC:8671
Homologene: 49565
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 93,385,620 bp
  • T to C, chromosome 1 at 130,934,995 bp
  • T to A, chromosome 2 at 37,201,556 bp
  • A to C, chromosome 2 at 39,004,156 bp
  • G to T, chromosome 2 at 157,914,729 bp
  • T to A, chromosome 2 at 160,748,283 bp
  • T to C, chromosome 3 at 93,670,806 bp
  • T to C, chromosome 3 at 106,202,767 bp
  • T to G, chromosome 3 at 106,214,348 bp
  • G to A, chromosome 3 at 139,701,774 bp
  • A to G, chromosome 3 at 141,801,293 bp
  • A to T, chromosome 4 at 26,336,718 bp
  • A to G, chromosome 4 at 85,049,827 bp
  • T to A, chromosome 4 at 120,098,369 bp
  • G to A, chromosome 4 at 129,182,103 bp
  • G to A, chromosome 5 at 10,243,010 bp
  • T to C, chromosome 5 at 67,326,862 bp
  • A to G, chromosome 5 at 118,726,265 bp
  • T to A, chromosome 6 at 31,524,733 bp
  • G to T, chromosome 6 at 125,655,044 bp
  • A to G, chromosome 7 at 12,616,074 bp
  • A to T, chromosome 7 at 25,273,444 bp
  • A to G, chromosome 7 at 30,609,811 bp
  • A to G, chromosome 7 at 43,641,976 bp
  • T to G, chromosome 7 at 56,203,849 bp
  • A to C, chromosome 7 at 84,615,869 bp
  • A to T, chromosome 7 at 85,749,803 bp
  • A to T, chromosome 8 at 36,230,510 bp
  • T to A, chromosome 8 at 43,183,333 bp
  • G to A, chromosome 8 at 85,518,052 bp
  • A to T, chromosome 9 at 7,075,788 bp
  • G to T, chromosome 9 at 20,825,327 bp
  • G to C, chromosome 9 at 39,719,677 bp
  • A to T, chromosome 9 at 110,506,664 bp
  • A to C, chromosome 9 at 110,986,699 bp
  • T to A, chromosome 10 at 67,158,001 bp
  • A to T, chromosome 10 at 77,947,931 bp
  • A to C, chromosome 10 at 81,154,453 bp
  • T to C, chromosome 11 at 4,148,889 bp
  • A to G, chromosome 11 at 75,526,078 bp
  • T to C, chromosome 11 at 95,511,066 bp
  • A to G, chromosome 11 at 103,618,799 bp
  • G to C, chromosome 12 at 7,995,539 bp
  • T to A, chromosome 12 at 32,205,667 bp
  • T to C, chromosome 13 at 8,731,845 bp
  • A to T, chromosome 13 at 100,629,517 bp
  • T to C, chromosome 13 at 104,312,759 bp
  • A to G, chromosome 14 at 23,463,156 bp
  • T to A, chromosome 15 at 82,790,202 bp
  • T to C, chromosome 16 at 31,254,718 bp
  • A to G, chromosome 17 at 12,842,437 bp
  • A to G, chromosome 17 at 50,606,464 bp
  • C to G, chromosome 17 at 56,451,697 bp
  • T to A, chromosome 17 at 73,830,184 bp
  • A to G, chromosome 18 at 36,961,704 bp
  • A to G, chromosome 18 at 82,620,337 bp
  • T to C, chromosome 19 at 27,324,048 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7113 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045205-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.