Strain Name:
C57BL/6J-MtgxR7061Btlr/Mmmh
Stock Number:
045384-MU
Citation ID:
RRID:MMRRC_045384-MU
Other Names:
R7061 (G1)
Major Collection:

Strain Information

Rnf10
Name: ring finger protein 10
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 50849
Homologene: 40990
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 2610510B01Rik, 0610038M01Rik, Dopey2
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Aard
Name: alanine and arginine rich domain containing protein
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239435
Homologene: 17041
Dock5
Name: dedicator of cytokinesis 5
Synonyms: rlc, 1110060D06Rik, lr2
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 68813
VEGA: 14
Homologene: 57016
Csnk2a1
Name: casein kinase 2, alpha 1 polypeptide
Synonyms: CK2, Csnk2a1-rs4
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12995
Homologene: 90874
Hmgcr
Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
Synonyms: Red, 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 15357
HGNC: HGNC:5006
Homologene: 30994
Erp44
Name: endoplasmic reticulum protein 44
Synonyms: Txndc4, 1110001E24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 76299
Homologene: 12638
Urb2
Name: URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 382038
Homologene: 8859
Helz
Name: helicase with zinc finger domain
Synonyms: 3110078M01Rik, 9630002H22Rik, 9430093I07Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 78455
Homologene: 8918
Epc2
Name: enhancer of polycomb homolog 2
Synonyms: D2Ertd694e
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227867
Homologene: 32274
Xpo7
Name: exportin 7
Synonyms: 4930506C02Rik, Ranbp16
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 65246
VEGA: 14
Homologene: 22857
Dclk2
Name: doublecortin-like kinase 2
Synonyms: 6330415M09Rik, Click-II, Dcamkl2
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70762
Homologene: 69431
Rab5c
Name: RAB5C, member RAS oncogene family
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 19345
HGNC: HGNC:9785
Homologene: 55533
Neo1
Name: neogenin
Synonyms: Igdcc2, 2610028H22Rik, D930014N22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18007
VEGA: 9
HGNC: HGNC:7754
Homologene: 1870
Ibsp
Name: integrin binding sialoprotein
Synonyms: Bsp, BSP, bone sialoprotein, Bsp2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15891
HGNC: HGNC:5341
Homologene: 3644
Hnrnpu
Name: heterogeneous nuclear ribonucleoprotein U
Synonyms: scaffold attachment factor A, Sp120, Hnrpu
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 51810
HGNC: HGNC:5048
Homologene: 22991
Chd6
Name: chromodomain helicase DNA binding protein 6
Synonyms: 6330406J24Rik, 5430439G14Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 71389
Homologene: 32772
Rrbp1
Name: ribosome binding protein 1
Synonyms: ES/130, 1700087N07Rik, mRRp47, mRRp41, mRRp15a, 5730465C04Rik, mRRp15b, mRRp16.8, mRRp10, mRRp5.4, mRRp2, mRRp1.8, p180, mRRp0
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 81910
Homologene: 68138
Zfp574
Name: zinc finger protein 574
Synonyms: A630056B21Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 232976
Homologene: 11238
Vit
Name: vitrin
Synonyms: 2810429K11Rik, akhirin, 1700110E08Rik, AKH, 1700052E02Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 74199
VEGA: 17
Homologene: 24942
Grm2
Name: glutamate receptor, metabotropic 2
Synonyms: 4930441L02Rik, Gprc1b, mGluR2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 108068
HGNC: HGNC:4594
Homologene: 20229
Fli1
Name: Friend leukemia integration 1
Synonyms: SIC-1, Sic1, Fli-1, EWSR2
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 14247
HGNC: HGNC:3749
Homologene: 55624
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hyrh, hy-3, hy3, 1700034M11Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244653
Homologene: 52118
Tns2
Name: tensin 2
Synonyms: nep, nph, Tenc1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 209039
VEGA: 15
Homologene: 37077
Ttn
Name: titin
Synonyms: shru, L56, mdm, connectin, D330041I19Rik, 2310057K23Rik, 2310074I15Rik, 2310036G12Rik, D830007G01Rik, 1100001C23Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 22138
Homologene: 130650
Depdc1a
Name: DEP domain containing 1a
Synonyms: 5830484J08Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 76131
Homologene: 9834
Zfp608
Name: zinc finger protein 608
Synonyms: 4932417D18Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 269023
VEGA: 18
Homologene: 18485
Mybpc3
Name: myosin binding protein C, cardiac
Synonyms: cardiac C-protein
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17868
HGNC: HGNC:7551
Homologene: 215
Helz2
Name: helicase with zinc finger 2, transcriptional coactivator
Synonyms: BC006779
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 229003
Homologene: 14118
Ap3b2
Name: adaptor-related protein complex 3, beta 2 subunit
Synonyms: Naptb, beta3B
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 11775
HGNC: HGNC:567
Homologene: 55837
Man1a
Name: mannosidase 1, alpha
Synonyms: PCR1, mannosyl-oligosaccharide alpha-1,2-mannosidase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 17155
HGNC: HGNC:6821
Homologene: 4316
Slc6a9
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9
Synonyms: Glyt1, Glyt-1
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 14664
Homologene: 5050
Dennd5a
Name: DENN domain containing 5A
Synonyms: 1500012B19Rik, ORF37, Rab6ip1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 19347
Homologene: 14584
Phactr1
Name: phosphatase and actin regulator 1
Synonyms: Rpel1, 9630030F18Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 218194
Homologene: 33597
Kcnh2
Name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Synonyms: ether a go-go related, LQT, ERG1, Lqt2, merg1b, M-erg, merg1a
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 16511
HGNC: HGNC:6251
Homologene: 201
Abcb5
Name: ATP-binding cassette, sub-family B member 5
Synonyms: 9230106F14Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 77706
HGNC: HGNC:46
Homologene: 83488
Mical2
Name: microtubule associated monooxygenase, calponin and LIM domain containing 2
Synonyms: Micalcl, Ebitein1, 4921517J23Rik, 5330438E18Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 320878
Homologene: 8760
Celsr3
Name: cadherin, EGF LAG seven-pass G-type receptor 3
Synonyms: Adgrc3, flamingo, Fmi1
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 107934
HGNC: HGNC:3230
Homologene: 1077
Fbxo41
Name: F-box protein 41
Synonyms: D6Ertd538e
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330369
Homologene: 19837
Ugt3a2
Name: UDP glycosyltransferases 3 family, polypeptide A2
Synonyms: Ugt3a, Ugt3a1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 105887
Homologene: 122787
Bpifa6
Name: BPI fold containing family A, member 6
Synonyms: Gm5840
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 545477
Homologene: 129594
Col5a1
Name: collagen, type V, alpha 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 12831
HGNC: HGNC:2209
Homologene: 55434
Dsg1c
Name: desmoglein 1 gamma
Synonyms: Dsg6
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 211924
HGNC: HGNC:3048
Meiosin
Name: meiosis initiator
Synonyms: Bhmg1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 243866
Homologene: 131804
Adgrb1
Name: adhesion G protein-coupled receptor B1
Synonyms: B830018M07Rik, Bai1
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 107831
HGNC: HGNC:943
Homologene: 1287
Vmn1r60
Name: vomeronasal 1 receptor 60
Synonyms: Gm7184
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 636697
Homologene: 41799
Prob1
Name: proline rich basic protein 1
Synonyms: Gm1614, LOC381148
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 381148
Homologene: 83773
Grk5
Name: G protein-coupled receptor kinase 5
Synonyms: Gprk5
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 14773
VEGA: 19
HGNC: HGNC:4544
Homologene: 3879
Pkn3
Name: protein kinase N3
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 263803
Homologene: 50980
Vmn2r16
Name: vomeronasal 2, receptor 16
Synonyms: EG384220
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384220
Homologene: 104825
Evc
Name: EvC ciliary complex subunit 1
Synonyms: Ellis van Creveld gene syndrome
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 59056
HGNC: HGNC:3497
Homologene: 10949
Iqca1l
Name: IQ motif containing with AAA domain 1 like
Synonyms: 4931409K22Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231045
Homologene: 18602
Il24
Name: interleukin 24
Synonyms: FISP, Mda-7
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 93672
Homologene: 4991
Cpox
Name: coproporphyrinogen oxidase
Synonyms: Cpo, M100835, clone 560, cac, nct
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 12892
VEGA: 16
HGNC: HGNC:2321
Homologene: 76
Or5bw2
Name: olfactory receptor family 5 subfamily BW member 2
Synonyms: Olfr1350, MOR222-3, GA_x6K02T2QGBW-3300391-3301317
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258384
Or52n5
Name: olfactory receptor family 52 subfamily N member 5
Synonyms: GA_x6K02T2PBJ9-7567376-7568329, Olfr669, MOR34-6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 259045
Homologene: 72057
Zfp69
Name: zinc finger protein 69
Synonyms: LOC381549, Zfp63, KRAB2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 381549
Homologene: 45693
Smo
Name: smoothened, frizzled class receptor
Synonyms: E130215L21Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 319757
Homologene: 4115
Rhebl1
Name: Ras homolog enriched in brain like 1
Synonyms: Rheb2, 1810036J22Rik
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 69159
Homologene: 5477
Nlrp6
Name: NLR family, pyrin domain containing 6
Synonyms: Nalp6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 101613
Homologene: 15881
Or8b9
Name: olfactory receptor family 8 subfamily B member 9
Synonyms: MOR161-5, GA_x6K02T2PVTD-31540342-31541277, Olfr877
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258412
Homologene: 121556
Igfals
Name: insulin-like growth factor binding protein, acid labile subunit
Synonyms: ALS, Albs
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 16005
VEGA: 17
HGNC: HGNC:5468
Homologene: 37987
Mfsd4b1
Name: major facilitator superfamily domain containing 4B1
Synonyms: AI317395
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 215929
Homologene: 77426
Rab14
Name: RAB14, member RAS oncogene family
Synonyms: 0610030G24Rik, D030017L14Rik, 2810475J17Rik, A830021G03Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 68365
Homologene: 48679
Speer1f
Name: spermatogenesis associated glutamate (E)-rich protein 1F
Synonyms: Gm8897
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 667961
Pcdhgb5
Name: protocadherin gamma subfamily B, 5
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93702
HGNC: HGNC:8712
Homologene: 55773
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 130,883,371 bp
  • T to C, chromosome 1 at 178,336,126 bp
  • C to A, chromosome 2 at 28,025,678 bp
  • T to A, chromosome 2 at 30,083,536 bp
  • A to T, chromosome 2 at 35,183,417 bp
  • G to T, chromosome 2 at 49,535,322 bp
  • C to A, chromosome 2 at 76,894,692 bp
  • A to G, chromosome 2 at 91,125,404 bp
  • T to C, chromosome 2 at 143,989,167 bp
  • A to G, chromosome 2 at 150,408,017 bp
  • C to T, chromosome 2 at 152,274,171 bp
  • A to T, chromosome 2 at 153,992,316 bp
  • G to A, chromosome 2 at 161,025,965 bp
  • A to G, chromosome 2 at 181,240,514 bp
  • A to G, chromosome 3 at 86,831,731 bp
  • T to A, chromosome 3 at 159,522,852 bp
  • T to A, chromosome 4 at 48,219,375 bp
  • C to T, chromosome 4 at 117,868,064 bp
  • A to T, chromosome 4 at 120,931,401 bp
  • T to C, chromosome 5 at 11,419,104 bp
  • A to T, chromosome 5 at 24,331,922 bp
  • A to G, chromosome 5 at 24,545,065 bp
  • T to C, chromosome 5 at 37,319,102 bp
  • A to G, chromosome 5 at 104,309,902 bp
  • A to T, chromosome 5 at 109,363,754 bp
  • G to T, chromosome 5 at 115,257,090 bp
  • A to G, chromosome 6 at 29,760,230 bp
  • G to T, chromosome 6 at 85,475,466 bp
  • A to T, chromosome 7 at 5,544,311 bp
  • A to G, chromosome 7 at 6,570,783 bp
  • A to T, chromosome 7 at 19,100,128 bp
  • T to A, chromosome 7 at 25,080,197 bp
  • C to T, chromosome 7 at 81,461,009 bp
  • T to C, chromosome 7 at 104,938,676 bp
  • T to C, chromosome 7 at 109,905,179 bp
  • T to A, chromosome 7 at 112,346,801 bp
  • A to G, chromosome 7 at 140,922,867 bp
  • A to T, chromosome 8 at 110,603,288 bp
  • C to T, chromosome 8 at 124,028,297 bp
  • T to C, chromosome 9 at 32,424,222 bp
  • T to A, chromosome 9 at 37,855,646 bp
  • T to A, chromosome 9 at 58,990,441 bp
  • A to T, chromosome 9 at 106,651,225 bp
  • T to A, chromosome 9 at 108,847,594 bp
  • C to T, chromosome 10 at 40,003,386 bp
  • A to G, chromosome 10 at 53,920,235 bp
  • G to A, chromosome 11 at 100,719,963 bp
  • A to G, chromosome 11 at 107,649,177 bp
  • A to C, chromosome 12 at 118,877,774 bp
  • A to G, chromosome 13 at 43,132,981 bp
  • T to A, chromosome 13 at 96,666,148 bp
  • A to G, chromosome 14 at 67,770,254 bp
  • T to C, chromosome 14 at 70,671,072 bp
  • A to T, chromosome 15 at 9,306,154 bp
  • G to A, chromosome 15 at 52,040,221 bp
  • G to C, chromosome 15 at 74,569,881 bp
  • A to G, chromosome 15 at 98,879,283 bp
  • A to G, chromosome 15 at 102,104,479 bp
  • A to G, chromosome 16 at 58,670,860 bp
  • G to T, chromosome 16 at 93,762,063 bp
  • T to C, chromosome 17 at 24,880,307 bp
  • A to T, chromosome 17 at 78,625,156 bp
  • C to A, chromosome 18 at 20,277,009 bp
  • A to T, chromosome 18 at 35,654,500 bp
  • C to A, chromosome 18 at 37,731,923 bp
  • T to C, chromosome 18 at 54,987,997 bp
  • A to G, chromosome 19 at 61,046,092 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7061 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045384-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.