Strain Name:
C57BL/6J-MtgxR7800Btlr/Mmmh
Stock Number:
045855-MU
Citation ID:
RRID:MMRRC_045855-MU
Other Names:
R7800 (G1)
Major Collection:

Strain Information

Cnnm2
Name: cyclin M2
Synonyms: Acdp2
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 94219
VEGA: 19
HGNC: HGNC:103
Homologene: 9761
Ntrk3
Name: neurotrophic tyrosine kinase, receptor, type 3
Synonyms: TrkC
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 18213
HGNC: HGNC:8033
Homologene: 49183
Nup210l
Name: nucleoporin 210-like
Synonyms: 4930548O11Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 77595
Homologene: 28122
Wdr59
Name: WD repeat domain 59
Synonyms: 5430401O09Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 319481
Homologene: 38685
Naa25
Name: N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Synonyms: 4833422K13Rik, C330023M02Rik
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 231713
Homologene: 6891
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: RPC1, RPC155, 9330175N20Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 218832
VEGA: 14
Homologene: 5124
Camsap2
Name: calmodulin regulated spectrin-associated protein family, member 2
Synonyms: Camsap1l1, 1600013L13Rik, 4930541M15Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 67886
Homologene: 18927
Zfp407
Name: zinc finger protein 407
Synonyms: LOC240469, 6430585N13Rik, LOC381139
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 240476
Homologene: 86402
Rps6ka5
Name: ribosomal protein S6 kinase, polypeptide 5
Synonyms: MSK1, 6330404E13Rik, 3110005L17Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73086
VEGA: 12
Homologene: 48302
Cnot1
Name: CCR4-NOT transcription complex, subunit 1
Synonyms: 6030411K04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 234594
HGNC: HGNC:7877
Homologene: 9453
Cacnb1
Name: calcium channel, voltage-dependent, beta 1 subunit
Synonyms: Cchb1, Cchlb1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 12295
HGNC: HGNC:1401
Homologene: 20186
Actr10
Name: ARP10 actin-related protein 10
Synonyms: Arp11
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 56444
VEGA: 12
Homologene: 10220
Ermard
Name: ER membrane associated RNA degradation
Synonyms: 2410011O22Rik, 2210404J11Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381062
Homologene: 19936
Itgb1
Name: integrin beta 1 (fibronectin receptor beta)
Synonyms: 4633401G24Rik, beta1 integrin, CD29, Fnrb, Gm9863
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 16412
HGNC: HGNC:6153
Homologene: 22999
H1f3
Name: H1.3 linker histone, cluster member
Synonyms: Hist1h1d, H1.3, H1D, H1s-4, H1f3
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 14957
HGNC: HGNC:4717
Homologene: 68456
Lhx8
Name: LIM homeobox protein 8
Synonyms: Lhx7, L3
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 16875
Homologene: 62661
Nr3c2
Name: nuclear receptor subfamily 3, group C, member 2
Synonyms: mineralocorticoid receptor, Mlr, aldosterone receptor, MR
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 110784
HGNC: HGNC:7979
Homologene: 121495
Ces1h
Name: carboxylesterase 1H
Synonyms: 2310039D24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 75704
HGNC: HGNC:1863
Homologene: 119757
Gen1
Name: GEN1, Holliday junction 5' flap endonuclease
Synonyms: 5830483C08Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 209334
VEGA: 12
Homologene: 35313
Vmn1r167
Name: vomeronasal 1 receptor 167
Synonyms: Gm6279
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 622032
Homologene: 128341
Pcdha1
Name: protocadherin alpha 1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 116731
HGNC: HGNC:8663
Homologene: 75093
Abca6
Name: ATP-binding cassette, sub-family A member 6
Synonyms: 6330565N06Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76184
HGNC: HGNC:36
Homologene: 71264
Pde4dip
Name: phosphodiesterase 4D interacting protein (myomegalin)
Synonyms: D3Bwg1078e, D130016K21Rik, 9430063L05Rik, Usmg4, 4732458A06Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 83679
Homologene: 66961
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 628870
Homologene: 46008
Thbs2
Name: thrombospondin 2
Synonyms: Thrombospondin-2, Thbs-2, TSP2
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 21826
VEGA: 17
Homologene: 2438
Qrich2
Name: glutamine rich 2
Synonyms: LOC217341
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 217341
Homologene: 12951
Nrxn1
Name: neurexin I
Synonyms: alpha-latrotoxin receptor (calcium-dependent), 1700062G21Rik, neurexin I alpha, 9330127H16Rik, neurexin I alpha, neurexin I beta, neurexin I beta, neurexin I alpha, neurexin I beta, A230068P09Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 18189
HGNC: HGNC:8008
Homologene: 21005
Pcdhb9
Name: protocadherin beta 9
Synonyms: Pcdhb4C, PcdhbI
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93880
HGNC: HGNC:8689
Homologene: 87124
Extl1
Name: exostosin-like glycosyltransferase 1
Synonyms: D430033M16Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56219
HGNC: HGNC:3515
Homologene: 3277
Or8b53
Name: olfactory receptor family 8 subfamily B member 53
Synonyms: Olfr920, GA_x6K02T2PVTD-32458442-32459374, MOR165-6
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258783
VEGA: 9
Cers5
Name: ceramide synthase 5
Synonyms: 2310081H14Rik, Lass5, CerS5, Trh4
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 71949
Homologene: 23634
Clcnkb
Name: chloride channel, voltage-sensitive Kb
Synonyms: Clcnk2, Clcnk1l, Clck2, ClC-K2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 56365
Homologene: 107317
Or2ag12
Name: olfactory receptor family 2 subfamily AG member 12
Synonyms: MOR283-8, GA_x6K02T2PBJ9-9055944-9054994, Olfr693
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 258445
Slc6a13
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 13
Synonyms: Gat2, Gabt3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 14412
Homologene: 9592
Rigi
Name: RNA sensor RIG-I
Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 58, RIG-I, Ddx58, 6430573D20Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230073
Homologene: 32215
Pcdhb3
Name: protocadherin beta 3
Synonyms: PcdhbC
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93874
HGNC: HGNC:8688
Homologene: 115665
Ilvbl
Name: ilvB (bacterial acetolactate synthase)-like
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 216136
VEGA: 10
HGNC: HGNC:6041
Homologene: 68532
Ace
Name: angiotensin I converting enzyme
Synonyms: CD143
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 11421
HGNC: HGNC:2707
Homologene: 37351
Sult2a2
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
Synonyms: C730007P19Rik, Sth2, mSTa2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 100043194
Disp1
Name: dispatched RND transporter family member 1
Synonyms: DispA, 1190008H24Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 68897
Homologene: 14133
Pnlip
Name: pancreatic lipase
Synonyms: 1810007A24Rik, PTL, pancreatic triglyceride lipase
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 69060
VEGA: 19
HGNC: HGNC:9155
Homologene: 30999
Crisp4
Name: cysteine-rich secretory protein 4
Synonyms: 9230112K08Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 78081
HGNC: HGNC:304
Homologene: 81683
Pinx1
Name: PIN2/TERF1 interacting, telomerase inhibitor 1
Synonyms: 2610028A01Rik, LPTS, 2210403I16Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 72400
VEGA: 14
Homologene: 134540
Cby3
Name: chibby family member 3
Synonyms: 1700121K02Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 76653
Homologene: 67734
Zfp189
Name: zinc finger protein 189
Synonyms: C430015I23Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 230162
Homologene: 20737
Tmed9
Name: transmembrane p24 trafficking protein 9
Synonyms: p24alpha2, 2400003B06Rik
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 67511
VEGA: 13
Homologene: 68707
Igkv5-37
Name: immunoglobulin kappa variable 5-37
Synonyms: IgVk 23-37, LOC384417
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 384417
Trbc1
Name: T cell receptor beta, constant region 1
Synonyms: Gm16802, Tcrb-C1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 100125262
Sord
Name: sorbitol dehydrogenase
Synonyms: Sdh1, Sodh-1, Sdh-1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 20322
Homologene: 56080
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to C, chromosome 1 at 18,128,749 bp
  • T to C, chromosome 1 at 136,281,901 bp
  • C to T, chromosome 1 at 183,098,986 bp
  • T to C, chromosome 2 at 122,259,080 bp
  • A to G, chromosome 3 at 90,134,597 bp
  • C to T, chromosome 3 at 97,715,283 bp
  • A to G, chromosome 3 at 154,321,647 bp
  • T to C, chromosome 4 at 40,211,618 bp
  • C to T, chromosome 4 at 49,529,367 bp
  • C to T, chromosome 4 at 134,371,618 bp
  • T to C, chromosome 4 at 141,414,522 bp
  • A to G, chromosome 5 at 121,424,531 bp
  • A to G, chromosome 6 at 41,539,261 bp
  • A to C, chromosome 6 at 69,963,515 bp
  • T to A, chromosome 6 at 121,321,699 bp
  • A to G, chromosome 7 at 13,734,785 bp
  • A to T, chromosome 7 at 23,504,644 bp
  • T to A, chromosome 7 at 78,302,740 bp
  • A to G, chromosome 7 at 103,250,834 bp
  • A to G, chromosome 7 at 106,677,574 bp
  • A to G, chromosome 8 at 76,909,992 bp
  • A to T, chromosome 8 at 93,379,694 bp
  • A to G, chromosome 8 at 95,765,062 bp
  • C to A, chromosome 8 at 111,521,938 bp
  • A to G, chromosome 8 at 128,713,237 bp
  • T to G, chromosome 9 at 38,756,618 bp
  • C to T, chromosome 10 at 78,583,975 bp
  • T to A, chromosome 10 at 107,886,515 bp
  • T to C, chromosome 11 at 50,359,348 bp
  • T to G, chromosome 11 at 98,009,295 bp
  • T to C, chromosome 11 at 105,986,058 bp
  • T to C, chromosome 11 at 110,187,872 bp
  • G to T, chromosome 11 at 116,456,860 bp
  • T to C, chromosome 12 at 11,241,862 bp
  • T to G, chromosome 12 at 70,943,509 bp
  • G to A, chromosome 12 at 100,558,565 bp
  • C to A, chromosome 13 at 23,555,367 bp
  • A to G, chromosome 13 at 55,595,532 bp
  • C to A, chromosome 14 at 24,484,387 bp
  • A to G, chromosome 14 at 63,919,535 bp
  • G to T, chromosome 15 at 99,736,241 bp
  • T to C, chromosome 17 at 14,676,296 bp
  • G to A, chromosome 17 at 15,056,803 bp
  • C to T, chromosome 17 at 91,089,207 bp
  • T to A, chromosome 18 at 36,931,373 bp
  • T to A, chromosome 18 at 37,301,921 bp
  • A to C, chromosome 18 at 37,401,549 bp
  • C to T, chromosome 18 at 84,560,675 bp
  • A to G, chromosome 19 at 46,877,981 bp
  • T to C, chromosome 19 at 58,681,702 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R7800 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
045855-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.