Strain Name:
C57BL/6J-MtgxR8492Btlr/Mmmh
Stock Number:
067934-MU
Citation ID:
RRID:MMRRC_067934-MU
Other Names:
R8492 (G1)
Major Collection:

Strain Information

Rpl13a
Name: ribosomal protein L13A
Synonyms: tum-transplantation antigen P198, 1810026N22Rik, tum-antigen, Tstap198-7
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 22121
Homologene: 111053
D630045J12Rik
Name: RIKEN cDNA D630045J12 gene
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 330286
Homologene: 19782
Prok2
Name: prokineticin 2
Synonyms: Bombina variegata 8kDa protein, Bv8, PK2
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 50501
Homologene: 9268
Asah2
Name: N-acylsphingosine amidohydrolase 2
Synonyms: neutral/alkaline ceramidase
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 54447
VEGA: 19
Homologene: 10310
Triobp
Name: TRIO and F-actin binding protein
Synonyms: Tara, Mus EST 478828, EST478828
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 110253
Homologene: 5104
Nf1
Name: neurofibromin 1
Synonyms: Mhdadsk9, neurofibromin, Nf-1, Dsk9
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18015
HGNC: HGNC:7765
Homologene: 226
Tdh
Name: L-threonine dehydrogenase
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 58865
Homologene: 10987
Rapgef6
Name: Rap guanine nucleotide exchange factor (GEF) 6
Synonyms: PDZ-GEF2, RA-GEF-2, C030018K18Rik, Pdzgef2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192786
Homologene: 22968
Ap3b1
Name: adaptor-related protein complex 3, beta 1 subunit
Synonyms: AP-3, Hps2, beta3A, recombination induced mutation 2, rim2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 11774
VEGA: 13
HGNC: HGNC:566
Homologene: 68125
Eif3c
Name: eukaryotic translation initiation factor 3, subunit C
Synonyms: NIPIL(A3), Xsl, Eif3s8, 3230401O13Rik, Xs, 110kDa
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56347
Homologene: 2781
Inppl1
Name: inositol polyphosphate phosphatase-like 1
Synonyms: SHIP2
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16332
HGNC: HGNC:6080
Homologene: 1204
Cenpf
Name: centromere protein F
Synonyms: mitosin, Lek1, 6530404A22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Als2
Name: alsin Rho guanine nucleotide exchange factor
Synonyms: Als2cr6, 3222402C23Rik, 9430073A21Rik, Alsin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74018
HGNC: HGNC:443
Homologene: 23264
Zzef1
Name: zinc finger, ZZ-type with EF hand domain 1
Synonyms: 8430405D05Rik, C130099L13Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 195018
Homologene: 9027
Ift122
Name: intraflagellar transport 122
Synonyms: sopb, Wdr10, C86139
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 81896
Homologene: 12819
Robo1
Name: roundabout guidance receptor 1
Synonyms: DUTT1
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 19876
Homologene: 2206
Arhgap23
Name: Rho GTPase activating protein 23
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 58996
Homologene: 104145
Taf1c
Name: TATA-box binding protein associated factor, RNA polymerase I, C
Synonyms: mTAFI95
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 21341
Homologene: 21163
Shld2
Name: shieldin complex subunit 2
Synonyms: Fam35a, 3110001K24Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 75698
VEGA: 14
Homologene: 56840
Cemip
Name: cell migration inducing protein, hyaluronan binding
Synonyms: Hybid, 6330404C01Rik, 12H19.01.T7, 9930013L23Rik
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 80982
Homologene: 10268
Apip
Name: APAF1 interacting protein
Synonyms: CGI-29, APIP2, Mmrp19
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 56369
Homologene: 6277
Cep170b
Name: centrosomal protein 170B
Synonyms: AW555464
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217882
VEGA: 12
Homologene: 46165
Ccdc174
Name: coiled-coil domain containing 174
Synonyms: C130022K22Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232236
Homologene: 9523
Zic5
Name: zinc finger protein of the cerebellum 5
Synonyms: 1700049L20Rik, Opr, odd-paired related
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 65100
Homologene: 11301
Colec12
Name: collectin sub-family member 12
Synonyms: Scara4, SRCL, CL-P1
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 140792
VEGA: 18
Homologene: 34248
Rhob
Name: ras homolog family member B
Synonyms: Arhb
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 11852
VEGA: 12
HGNC: HGNC:668
Homologene: 68377
Ncoa1
Name: nuclear receptor coactivator 1
Synonyms: KAT13A, bHLHe74, SRC-1, SRC-a/NCoA-1, steroid receptor coactivator-1, SRC1
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 17977
VEGA: 12
HGNC: HGNC:7668
Homologene: 7859
Ankrd35
Name: ankyrin repeat domain 35
Synonyms: 4732436F15Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 213121
Homologene: 16977
G6pc2
Name: glucose-6-phosphatase, catalytic, 2
Synonyms: IGRP, islet specific glucose-6-phosphatase, G6pc-rs
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14378
Homologene: 41423
Ralgapa2
Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Synonyms: RGC2, A230067G21Rik, AS250
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 241694
Homologene: 28131
Neb
Name: nebulin
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 17996
HGNC: HGNC:7720
Homologene: 136285
Dlgap2
Name: DLG associated protein 2
Synonyms: PSD-95/SAP90-binding protein 2, SAP90/PSD-95-associated protein 2, Sapap2, DAP2, 6430596N04Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244310
HGNC: HGNC:2906
Homologene: 3484
Cytip
Name: cytohesin 1 interacting protein
Synonyms: A130053M09Rik, Cbp, Pscdbp, Cybr
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 227929
HGNC: HGNC:9506
Homologene: 3167
Ndufb5
Name: NADH:ubiquinone oxidoreductase subunit B5
Synonyms: 0610007D05Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 66046
HGNC: HGNC:7700
Homologene: 31093
Vmn1r53
Name: vomeronasal 1 receptor 53
Synonyms: VN5, V1rb3
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 113853
Homologene: 113975
Krt84
Name: keratin 84
Synonyms: HRb-1, Krt2-16, Krt2-3
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 16680
VEGA: 15
HGNC: HGNC:6461
Homologene: 22473
Trpv3
Name: transient receptor potential cation channel, subfamily V, member 3
Synonyms: Nh, VRL3, 1110036I10Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 246788
Homologene: 17040
Serpinb9f
Name: serine (or cysteine) peptidase inhibitor, clade B, member 9f
Synonyms: NK21, Spi13, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 20709
HGNC: HGNC:8955
Homologene: 69093
Ccng2
Name: cyclin G2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 12452
HGNC: HGNC:1593
Homologene: 3208
Tmpo
Name: thymopoietin
Synonyms: 5630400D24Rik, lamina-associated polypeptide 2, LAP2, TP
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 21917
VEGA: 10
Homologene: 31144
Ankmy2
Name: ankyrin repeat and MYND domain containing 2
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 217473
VEGA: 12
Homologene: 10662
Snx14
Name: sorting nexin 14
Synonyms: YR-14, C330035N22Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 244962
Homologene: 17823
Zdhhc14
Name: zinc finger, DHHC domain containing 14
Synonyms: B530001K09Rik, New1cp
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224454
VEGA: 17
Homologene: 62301
Vmn1r215
Name: vomeronasal 1 receptor 215
Synonyms: V1ri2
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 171253
Homologene: 110880
Abcc2
Name: ATP-binding cassette, sub-family member 2
Synonyms: multidrug resistance protein 2, Mrp2, Cmoat
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 12780
HGNC: HGNC:53
Homologene: 68052
Miip
Name: migration and invasion inhibitory protein
Synonyms: D4Wsu114e
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 28010
Homologene: 15879
9330159F19Rik
Name: RIKEN cDNA 9330159F19 gene
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 212448
VEGA: 10
Homologene: 8804
Vmn2r112
Name: vomeronasal 2, receptor 112
Synonyms: EG628185
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 628185
Homologene: 86604
Zfp109
Name: zinc finger protein 109
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 56869
Slc22a8
Name: solute carrier family 22 (organic anion transporter), member 8
Synonyms: Roct, mOat3, OAT3
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 19879
VEGA: 19
Homologene: 20901
Disc1
Name: disrupted in schizophrenia 1
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 244667
HGNC: HGNC:2888
Homologene: 10257
Plekhg3
Name: pleckstrin homology domain containing, family G (with RhoGef domain) member 3
Synonyms: MGC40768
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 263406
VEGA: 12
Homologene: 77478
Ppm1f
Name: protein phosphatase 1F (PP2C domain containing)
Synonyms: 1110021B16Rik, 4933427B07Rik
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 68606
Homologene: 22828
Dync2li1
Name: dynein cytoplasmic 2 light intermediate chain 1
Synonyms: mD2LIC, D2lic, 4933404O11Rik, LIC3, CGI-60
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 213575
VEGA: 17
Homologene: 9336
Rnf141
Name: ring finger protein 141
Synonyms: 2610110L04Rik, ZFP36, ZNF230
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 67150
Homologene: 9503
Tmem156
Name: transmembrane protein 156
Synonyms: LOC243025
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 243025
Homologene: 49811
Trim56
Name: tripartite motif-containing 56
Synonyms: A130009K11Rik, RNF109, LOC384309
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 384309
Homologene: 12812
Hspb1
Name: heat shock protein 1
Synonyms: Hsp25
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 15507
HGNC: HGNC:5246
Homologene: 1180
Slc5a10
Name: solute carrier family 5 (sodium/glucose cotransporter), member 10
Synonyms: C330021F16Rik, SGLT5
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 109342
Homologene: 65037
Aloxe3
Name: arachidonate lipoxygenase 3
Synonyms: e-LOX-3
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 23801
Homologene: 8013
Hba-x
Name: hemoglobin X, alpha-like embryonic chain in Hba complex
Synonyms: zeta globin
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 15126
HGNC: HGNC:4835
Homologene: 110705
Gm5145
Name: predicted pseudogene 5145
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 381065
VEGA: 17
Tssk3
Name: testis-specific serine kinase 3
Synonyms: Stk22c, 4930594I21Rik, Tssk-3, Stk22d, 1700014N07Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 58864
Homologene: 62163
Malrd1
Name: MAM and LDL receptor class A domain containing 1
Synonyms: Gm13364, Gm13318, Diet1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 102635496
Homologene: 136214
Or12k7
Name: olfactory receptor family 12 subfamily K member 7
Synonyms: GA_x6K02T2NLDC-33760081-33761034, MOR159-1, Olfr360
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258615
Homologene: 73997
Mettl21e
Name: methyltransferase like 21E
Synonyms: 4832428D23Rik, LOC381340
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 403183
Homologene: 19006
Pcdhgc3
Name: protocadherin gamma subfamily C, 3
Synonyms: Pcdh2, PC43
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 93706
HGNC: HGNC:8716
Homologene: 31099
G530012D18Rik
Name: RIKEN cDNA G530012D1 gene
Type: Gene
Species: Mouse
Chromosome: 1
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 44,206,393 bp
  • T to C, chromosome 1 at 59,211,344 bp
  • C to G, chromosome 1 at 85,577,214 bp
  • A to G, chromosome 1 at 189,658,729 bp
  • T to G, chromosome 2 at 15,610,123 bp
  • T to A, chromosome 2 at 37,068,683 bp
  • T to C, chromosome 2 at 52,313,212 bp
  • A to G, chromosome 2 at 58,137,857 bp
  • A to G, chromosome 2 at 69,220,242 bp
  • T to A, chromosome 2 at 103,092,521 bp
  • A to T, chromosome 2 at 146,342,604 bp
  • T to G, chromosome 3 at 32,751,228 bp
  • T to G, chromosome 3 at 96,682,213 bp
  • T to C, chromosome 4 at 129,489,652 bp
  • T to C, chromosome 4 at 147,861,424 bp
  • A to T, chromosome 5 at 65,065,095 bp
  • A to C, chromosome 5 at 93,271,454 bp
  • G to A, chromosome 5 at 135,889,368 bp
  • A to C, chromosome 5 at 137,112,929 bp
  • A to T, chromosome 6 at 38,190,590 bp
  • A to G, chromosome 6 at 90,223,412 bp
  • G to C, chromosome 6 at 91,888,157 bp
  • A to T, chromosome 6 at 99,714,476 bp
  • T to A, chromosome 6 at 115,887,005 bp
  • T to C, chromosome 7 at 24,228,074 bp
  • A to G, chromosome 7 at 45,126,521 bp
  • A to G, chromosome 7 at 83,973,214 bp
  • A to T, chromosome 7 at 101,826,778 bp
  • T to G, chromosome 7 at 110,837,200 bp
  • C to T, chromosome 7 at 126,563,110 bp
  • A to T, chromosome 8 at 14,778,271 bp
  • G to A, chromosome 8 at 119,598,717 bp
  • T to A, chromosome 8 at 125,090,438 bp
  • T to C, chromosome 9 at 88,381,816 bp
  • G to A, chromosome 10 at 29,218,247 bp
  • C to A, chromosome 10 at 91,161,858 bp
  • T to A, chromosome 11 at 32,277,921 bp
  • T to G, chromosome 11 at 54,690,237 bp
  • A to G, chromosome 11 at 61,673,983 bp
  • A to T, chromosome 11 at 69,126,475 bp
  • T to G, chromosome 11 at 72,872,604 bp
  • T to A, chromosome 11 at 72,886,746 bp
  • G to A, chromosome 11 at 73,288,209 bp
  • T to A, chromosome 11 at 79,408,422 bp
  • A to G, chromosome 11 at 97,475,021 bp
  • T to C, chromosome 12 at 4,263,473 bp
  • G to T, chromosome 12 at 8,499,531 bp
  • A to T, chromosome 12 at 36,176,591 bp
  • G to T, chromosome 12 at 76,576,016 bp
  • G to A, chromosome 12 at 112,744,700 bp
  • A to T, chromosome 13 at 23,075,886 bp
  • C to A, chromosome 13 at 33,334,604 bp
  • A to G, chromosome 13 at 94,394,786 bp
  • T to A, chromosome 14 at 34,245,232 bp
  • C to A, chromosome 14 at 63,492,820 bp
  • G to T, chromosome 14 at 122,465,062 bp
  • C to T, chromosome 15 at 78,994,126 bp
  • C to A, chromosome 15 at 101,529,616 bp
  • T to C, chromosome 16 at 16,915,178 bp
  • T to C, chromosome 16 at 73,013,023 bp
  • G to A, chromosome 17 at 5,712,414 bp
  • A to T, chromosome 17 at 20,570,419 bp
  • A to G, chromosome 17 at 22,602,489 bp
  • C to A, chromosome 17 at 84,649,706 bp
  • T to A, chromosome 18 at 9,876,980 bp
  • T to A, chromosome 18 at 37,807,294 bp
  • G to T, chromosome 19 at 8,594,231 bp
  • G to A, chromosome 19 at 32,006,259 bp
  • A to T, chromosome 19 at 43,804,971 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R8492 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
067934-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.