Strain Name:
C57BL/6J-MtgxR9042Btlr/Mmmh
Stock Number:
068869-MU
Citation ID:
RRID:MMRRC_068869-MU
Other Names:
R9042 (G1)
Major Collection:

Strain Information

Tanc1
Name: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
Synonyms: 1200003E16Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66860
Homologene: 18946
Prrc1
Name: proline-rich coiled-coil 1
Synonyms: 9430085A19Rik, 3110038B19Rik, 1190002C06Rik, 2310058D16Rik
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 73137
VEGA: 18
Homologene: 12491
Pmpca
Name: peptidase (mitochondrial processing) alpha
Synonyms: INPP5E, Alpha-MPP, 4933435E07Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 66865
Homologene: 6078
Tmem63b
Name: transmembrane protein 63b
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 224807
Homologene: 101682
Pkm
Name: pyruvate kinase, muscle
Synonyms: Pkm2, Pk-3, Pk-2, Pk3
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 18746
VEGA: 9
HGNC: HGNC:9021
Homologene: 37650
Nsrp1
Name: nuclear speckle regulatory protein 1
Synonyms: Ccdc55, NSpr70
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 237859
Homologene: 134095
Clasp2
Name: CLIP associating protein 2
Synonyms: 8030404L10Rik, CLASP2gamma, CLASP2beta, CLASP2, 1500004F14Rik, CLASP2alpha
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 76499
VEGA: 9
Homologene: 24944
Lta4h
Name: leukotriene A4 hydrolase
Synonyms: LTA4 hydrodase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 16993
VEGA: 10
HGNC: HGNC:6710
Homologene: 6820
Pafah1b1
Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
Synonyms: Pafaha, Lis1, PAF-AH 45, lissencephaly-1 protein, Mdsh, LIS-1
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 18472
HGNC: HGNC:8574
Homologene: 371
Atf7ip
Name: activating transcription factor 7 interacting protein
Synonyms: Mcaf1, ATFa-associated Modulator, AM, 2610204M12Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 54343
Homologene: 10051
Ube4b
Name: ubiquitination factor E4B
Synonyms: D4Bwg0973e, 4930551I19Rik, UFD2, Ufd2p, UFD2a, 4933406G05Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 63958
Homologene: 107623
Ipo5
Name: importin 5
Synonyms: IMB3, RanBP5, Kpnb3, 1110011C18Rik, importin beta 3, 5730478E03Rik
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 70572
VEGA: 14
HGNC: HGNC:6402
Homologene: 1710
Ncapd2
Name: non-SMC condensin I complex, subunit D2
Synonyms: CAP-D2, 2810406C15Rik, CNAP1, 2810465G24Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 68298
Homologene: 6497
Lrpprc
Name: leucine-rich PPR-motif containing
Synonyms: Lrp130, 3110001K13Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72416
Homologene: 32695
Pot1b
Name: protection of telomeres 1B
Synonyms: 2810458H16Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 72836
VEGA: 17
Homologene: 87058
Adamts12
Name: ADAM metallopeptidase with thrombospondin type 1 motif 12
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239337
VEGA: 15
Homologene: 12808
Pum3
Name: pumilio RNA-binding family member 3
Synonyms: 1110069H02Rik, D19Bwg1357e
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 52874
VEGA: 19
Homologene: 5762
Parp11
Name: poly (ADP-ribose) polymerase family, member 11
Synonyms: 5330431N24Rik, HIN1L
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 101187
HGNC: HGNC:1186
Homologene: 10680
Anpep
Name: alanyl aminopeptidase, membrane
Synonyms: Apn, aminopeptidase N, Cd13
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 16790
HGNC: HGNC:500
Homologene: 68163
Reln
Name: reelin
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 19699
HGNC: HGNC:9957
Homologene: 3699
Tmed4
Name: transmembrane p24 trafficking protein 4
Synonyms: 1110014L17Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 103694
Homologene: 5308
Lrp1b
Name: low density lipoprotein-related protein 1B
Synonyms: 9630004P12Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 94217
HGNC: HGNC:6693
Homologene: 56810
Ttc38
Name: tetratricopeptide repeat domain 38
Type: Gene
Species: Mouse
Chromosome: 15
NCBI: 239570
Homologene: 41208
Ecm2
Name: extracellular matrix protein 2, female organ and adipocyte specific
Synonyms: 9030618O22Rik, tenonectin
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 407800
VEGA: 13
HGNC: HGNC:3154
Homologene: 1064
Tmed6
Name: transmembrane p24 trafficking protein 6
Synonyms: 1810015P03Rik, 1810018I24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 66269
Homologene: 11938
Gpr22
Name: G protein-coupled receptor 22
Synonyms: 2900068K05Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 73010
HGNC: HGNC:4477
Homologene: 18420
Kcnh6
Name: potassium voltage-gated channel, subfamily H (eag-related), member 6
Synonyms: m-erg2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192775
Homologene: 32740
Spata31h1
Name: SPATA31 subfamily H member 1
Synonyms: 4932415D10Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 102635990
VEGA: 10
Homologene: 82476
Vmn2r53
Name: vomeronasal 2, receptor 53
Synonyms: EG637908
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 637908
Homologene: 104040
Cyp26b1
Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Synonyms: CP26, P450RAI-2, retinoic acid B1
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 232174
Homologene: 23179
Serpinb3c
Name: serine (or cysteine) peptidase inhibitor, clade B, member 3C
Synonyms: 1110013A16Rik, Scca2, Serpinb4, 1110001H02Rik, ovalbumin
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 381286
Homologene: 131278
Spata31e5
Name: spermatogenesis associated 31 subfamily E member 5
Synonyms: Gm597, LOC210962
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 210962
Grip1
Name: glutamate receptor interacting protein 1
Synonyms: eb, 4931400F03Rik
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 74053
Homologene: 12938
Nacad
Name: NAC alpha domain containing
Synonyms: mKIAA0363
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192950
Homologene: 135717
Psg18
Name: pregnancy specific beta-1-glycoprotein 18
Synonyms: Cea-3, Cea3, mmCGM6
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 26438
HGNC: HGNC:9524
Homologene: 110989
Slc40a1
Name: solute carrier family 40 (iron-regulated transporter), member 1
Synonyms: Dusg, IREG1, FPN1, ferroportin1, Pcm, Slc11a3, metal transporting protein 1, Ol5, MTP1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 53945
Homologene: 40959
Cpa6
Name: carboxypeptidase A6
Synonyms: 9030616D13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 329093
Homologene: 75130
Ndufaf7
Name: NADH:ubiquinone oxidoreductase complex assembly factor 7
Synonyms: 2410091C18Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 73694
VEGA: 17
Homologene: 12508
Amh
Name: anti-Mullerian hormone
Synonyms: MIS, Mullerian inhibiting substance
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 11705
VEGA: 10
HGNC: HGNC:464
Homologene: 68060
Rpe65
Name: retinal pigment epithelium 65
Synonyms: Mord1, A930029L06Rik, rd12
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 19892
Homologene: 20108
P2ry12
Name: purinergic receptor P2Y, G-protein coupled 12
Synonyms: P2Y12, 4921504D23Rik, 2900079B22Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 70839
Homologene: 11260
Serpina3a
Name: serine (or cysteine) peptidase inhibitor, clade A, member 3A
Synonyms: 4933406L18Rik, alpha-1 antiproteinase,, antitrypsin
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 74069
HGNC: HGNC:16
Phc3
Name: polyhomeotic 3
Synonyms: EDR3, HPH3, E030046K01Rik
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 241915
Homologene: 69390
Slc25a23
Name: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
Synonyms: 2310067G05Rik, SCaMC-3
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 66972
Homologene: 11467
Or8k3b
Name: olfactory receptor family 8 subfamily K member 3B
Synonyms: GA_x6K02T2Q125-48182406-48181465, Olfr1087, MOR188-5
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258843
Or1f19
Name: olfactory receptor family 1 subfamily F member 19
Synonyms: MOR131-1, Olfr161, GA_x54KRFPKG5P-112942-113883
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 258859
Homologene: 51784
Taf7
Name: TATA-box binding protein associated factor 7
Synonyms: 55kDa, Taf2f, TAFII55
Type: Gene
Species: Mouse
Chromosome: 18
NCBI: 24074
Homologene: 133942
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 10,337,290 bp
  • T to C, chromosome 1 at 28,776,956 bp
  • C to T, chromosome 1 at 45,909,461 bp
  • T to A, chromosome 1 at 107,272,001 bp
  • A to G, chromosome 2 at 26,393,569 bp
  • C to A, chromosome 2 at 41,502,017 bp
  • G to C, chromosome 2 at 59,843,422 bp
  • T to C, chromosome 2 at 86,690,795 bp
  • T to A, chromosome 3 at 30,929,767 bp
  • A to G, chromosome 3 at 59,218,035 bp
  • A to T, chromosome 3 at 159,615,655 bp
  • C to G, chromosome 4 at 149,360,376 bp
  • G to A, chromosome 5 at 22,048,038 bp
  • T to A, chromosome 6 at 84,576,608 bp
  • T to C, chromosome 6 at 125,179,338 bp
  • C to A, chromosome 6 at 127,471,652 bp
  • G to T, chromosome 6 at 136,561,265 bp
  • A to G, chromosome 7 at 12,581,508 bp
  • A to T, chromosome 7 at 18,349,122 bp
  • T to C, chromosome 7 at 79,838,762 bp
  • A to G, chromosome 8 at 107,063,753 bp
  • T to A, chromosome 9 at 59,671,937 bp
  • A to G, chromosome 9 at 113,905,997 bp
  • T to C, chromosome 10 at 80,806,609 bp
  • A to G, chromosome 10 at 82,287,351 bp
  • A to G, chromosome 10 at 93,482,988 bp
  • G to A, chromosome 10 at 120,000,533 bp
  • T to C, chromosome 11 at 6,274,405 bp
  • G to C, chromosome 11 at 6,598,948 bp
  • G to A, chromosome 11 at 74,683,667 bp
  • A to G, chromosome 11 at 77,050,651 bp
  • T to A, chromosome 11 at 106,017,638 bp
  • C to A, chromosome 12 at 31,709,854 bp
  • A to G, chromosome 12 at 104,116,103 bp
  • C to A, chromosome 13 at 49,528,963 bp
  • C to T, chromosome 14 at 120,923,135 bp
  • A to G, chromosome 15 at 11,152,048 bp
  • A to G, chromosome 15 at 85,836,109 bp
  • A to T, chromosome 16 at 3,593,268 bp
  • T to C, chromosome 17 at 45,666,591 bp
  • C to T, chromosome 17 at 55,699,991 bp
  • C to T, chromosome 17 at 57,045,553 bp
  • A to T, chromosome 17 at 78,938,539 bp
  • C to T, chromosome 17 at 84,752,308 bp
  • C to A, chromosome 18 at 37,643,170 bp
  • T to A, chromosome 18 at 57,374,692 bp
  • T to A, chromosome 19 at 27,422,391 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9042 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068869-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.