Strain Name:
C57BL/6J-MtgxR9207Btlr/Mmmh
Stock Number:
068981-MU
Citation ID:
RRID:MMRRC_068981-MU
Other Names:
R9207 (G1)
Major Collection:

Strain Information

Rad54l
Name: RAD54 like (S. cerevisiae)
Synonyms: RAD54
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 19366
HGNC: HGNC:9826
Homologene: 48227
Tyw1
Name: tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Synonyms: Rsafd1
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 100929
Homologene: 7068
Setdb1
Name: SET domain, bifurcated 1
Synonyms: ESET, KMT1E
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 84505
Homologene: 32157
Grm7
Name: glutamate receptor, metabotropic 7
Synonyms: Gpr1g, E130018M02Rik, mGluR7, mGlu7a receptor, 6330570A01Rik
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 108073
HGNC: HGNC:4599
Homologene: 20233
Pum2
Name: pumilio RNA-binding family member 2
Synonyms: Pumm2, 5730503J23Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 80913
Homologene: 69183
Irx4
Name: Iroquois homeobox 4
Type: Gene
Species: Mouse
Chromosome: 13
NCBI: 50916
HGNC: HGNC:6129
Homologene: 9485
Fibcd1
Name: fibrinogen C domain containing 1
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 98970
Homologene: 122246
Gad1
Name: glutamate decarboxylase 1
Synonyms: GAD25, GAD67, Gad-1, Z49976, GAD44, EP10
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 14415
HGNC: HGNC:4092
Homologene: 635
Bsdc1
Name: BSD domain containing 1
Synonyms: 1110063F24Rik
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 100383
Homologene: 32386
Hectd4
Name: HECT domain E3 ubiquitin protein ligase 4
Synonyms: Gm15800
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 269700
Homologene: 28297
Cdh23
Name: cadherin related 23 (otocadherin)
Synonyms: nmf112, 4930542A03Rik, USH1D, sals, ahl, bob, mdfw, nmf252, nmf181
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 22295
Homologene: 11142
Tex15
Name: testis expressed gene 15 meiosis and synapsis associated
Synonyms: 2210014E14Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 104271
Homologene: 12837
Spta1
Name: spectrin alpha, erythrocytic 1
Synonyms: Spna1, ihj, erythroid, Spna-1
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 20739
Homologene: 74460
Aadat
Name: aminoadipate aminotransferase
Synonyms: Kyat2, Kat2, mKat-2, KATII
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 23923
Homologene: 56540
Itgb4
Name: integrin beta 4
Synonyms: CD104
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 192897
HGNC: HGNC:6158
Homologene: 179
Or8b54
Name: olfactory receptor family 8 subfamily B member 54
Synonyms: MOR165-8, Olfr921, GA_x6K02T2PVTD-32478047-32478988
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 258778
VEGA: 9
Homologene: 128138
Tubd1
Name: tubulin, delta 1
Synonyms: 4930550G19Rik
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 56427
Homologene: 9443
Npas3
Name: neuronal PAS domain protein 3
Synonyms: bHLHe12, 4930423H22Rik
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 27386
VEGA: 12
Homologene: 8461
Ccdc39
Name: coiled-coil domain containing 39
Synonyms: b2b1304Clo, b2b2025.1Clo, b2b1735Clo, 4921507O14Rik, prh, D3Ertd789e
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 51938
Homologene: 12149
Frem3
Name: Fras1 related extracellular matrix protein 3
Synonyms: LOC333315
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 333315
Homologene: 35388
Tas2r120
Name: taste receptor, type 2, member 120
Synonyms: mGR20, T2R20, Tas2r20, mt2r47
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 387348
Homologene: 135705
Zfp110
Name: zinc finger protein 110
Synonyms: NRIF, 2900024E01Rik, Nrif1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 65020
Homologene: 129707
Axdnd1
Name: axonemal dynein light chain domain containing 1
Synonyms: LOC381304, 9430070O13Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 77352
Homologene: 52328
Adgrf1
Name: adhesion G protein-coupled receptor F1
Synonyms: Gpr110, 5031409J19Rik
Type: Gene
Species: Mouse
Chromosome: 17
NCBI: 77596
Homologene: 124643
Spag6l
Name: sperm associated antigen 6-like
Synonyms: Spag6, PF16
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 50525
Homologene: 8252
Begain
Name: brain-enriched guanylate kinase-associated
Synonyms: LOC380785
Type: Gene
Species: Mouse
Chromosome: 12
NCBI: 380785
Homologene: 10829
Tchhl1
Name: trichohyalin-like 1
Synonyms: S100a17, Thhl1
Type: Gene
Species: Mouse
Chromosome: 3
NCBI: 71325
Homologene: 84625
Rftn2
Name: raftlin family member 2
Synonyms: 2700010E02Rik, 3222401M22Rik
Type: Gene
Species: Mouse
Chromosome: 1
NCBI: 74013
Homologene: 16954
Tmem25
Name: transmembrane protein 25
Synonyms: 0610039J01Rik
Type: Gene
Species: Mouse
Chromosome: 9
NCBI: 71687
Homologene: 12403
Actrt2
Name: actin-related protein T2
Synonyms: 1700052K15Rik, Arp-T2, Arpm2
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 73353
Homologene: 23647
Timp4
Name: tissue inhibitor of metalloproteinase 4
Synonyms: TIMP-4
Type: Gene
Species: Mouse
Chromosome: 6
NCBI: 110595
Homologene: 37748
Or5b109
Name: olfactory receptor family 5 subfamily B member 109
Synonyms: Olfr1463, GA_x6K02T2RE5P-3560863-3561795, MOR202-29P
Type: Gene
Species: Mouse
Chromosome: 19
NCBI: 258120
HGNC: HGNC:8324
Homologene: 133886
Snai2
Name: snail family zinc finger 2
Synonyms: Slug, Snail2, Slugh
Type: Gene
Species: Mouse
Chromosome: 16
NCBI: 20583
VEGA: 16
Homologene: 31127
Smr2
Name: submaxillary gland androgen regulated protein 2
Synonyms: MSG2
Type: Gene
Species: Mouse
Chromosome: 5
NCBI: 20600
Krt32
Name: keratin 32
Synonyms: mHa2, Krt1-2
Type: Gene
Species: Mouse
Chromosome: 11
NCBI: 16670
HGNC: HGNC:6449
Homologene: 68246
Ftcd
Name: formiminotransferase cyclodeaminase
Synonyms: glutamate formiminotransferase
Type: Gene
Species: Mouse
Chromosome: 10
NCBI: 14317
HGNC: HGNC:3974
Homologene: 4848
Or4f47
Name: olfactory receptor family 4 subfamily F member 47
Synonyms: GA_x6K02T2Q125-73188162-73189112, MOR245-4, Olfr1317
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 258440
Homologene: 71983
Mpped2
Name: metallophosphoesterase domain containing 2
Synonyms: 239Fb, 2700082O15Rik
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 77015
HGNC: HGNC:1180
Homologene: 68190
Sult2a1
Name: sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
Synonyms: Std, Sth1, mSTa1
Type: Gene
Species: Mouse
Chromosome: 7
NCBI: 20859
Homologene: 37741
Efcab8
Name: EF-hand calcium binding domain 8
Synonyms: EG329541
Type: Gene
Species: Mouse
Chromosome: 2
NCBI: 100504221
Rnf166
Name: ring finger protein 166
Synonyms: Zfp313l, 1110031E24Rik
Type: Gene
Species: Mouse
Chromosome: 8
NCBI: 68718
Homologene: 35335
Gm8229
Name: predicted gene 8229
Type: Gene
Species: Mouse
Chromosome: 14
NCBI: 666675
Homologene: 128452
Ifnz
Name: interferon zeta
Synonyms: BGIF, 6030405N23Rik, Lmtn
Type: Gene
Species: Mouse
Chromosome: 4
NCBI: 319146
Homologene: 45671
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 55,184,990 bp
  • A to G, chromosome 1 at 156,388,046 bp
  • A to G, chromosome 1 at 174,211,573 bp
  • G to A, chromosome 2 at 31,816,443 bp
  • G to A, chromosome 2 at 70,579,202 bp
  • A to G, chromosome 2 at 106,866,974 bp
  • G to A, chromosome 2 at 112,142,052 bp
  • A to G, chromosome 2 at 153,814,419 bp
  • C to A, chromosome 3 at 33,832,557 bp
  • T to A, chromosome 3 at 93,470,512 bp
  • A to T, chromosome 3 at 95,338,802 bp
  • T to C, chromosome 4 at 88,783,288 bp
  • T to C, chromosome 4 at 116,110,018 bp
  • A to G, chromosome 4 at 129,469,037 bp
  • T to A, chromosome 4 at 154,667,463 bp
  • A to G, chromosome 5 at 88,108,867 bp
  • T to A, chromosome 5 at 121,295,433 bp
  • G to A, chromosome 5 at 130,269,224 bp
  • T to C, chromosome 6 at 111,358,913 bp
  • T to C, chromosome 6 at 115,247,309 bp
  • T to A, chromosome 6 at 132,657,663 bp
  • A to T, chromosome 7 at 12,848,558 bp
  • G to T, chromosome 7 at 13,832,702 bp
  • T to C, chromosome 8 at 33,575,756 bp
  • T to G, chromosome 8 at 60,526,623 bp
  • T to G, chromosome 8 at 80,613,442 bp
  • C to T, chromosome 8 at 122,468,329 bp
  • G to A, chromosome 9 at 38,775,664 bp
  • A to G, chromosome 9 at 44,799,179 bp
  • A to G, chromosome 10 at 60,407,431 bp
  • A to T, chromosome 10 at 76,587,139 bp
  • A to T, chromosome 11 at 86,565,711 bp
  • A to G, chromosome 11 at 100,086,754 bp
  • G to T, chromosome 11 at 116,007,097 bp
  • T to C, chromosome 12 at 8,713,904 bp
  • T to C, chromosome 12 at 54,068,035 bp
  • T to C, chromosome 12 at 109,033,324 bp
  • C to G, chromosome 13 at 73,268,530 bp
  • T to C, chromosome 14 at 44,368,781 bp
  • A to G, chromosome 15 at 76,173,917 bp
  • C to A, chromosome 16 at 14,707,082 bp
  • A to T, chromosome 16 at 16,780,628 bp
  • A to G, chromosome 17 at 43,310,273 bp
  • A to T, chromosome 19 at 13,235,036 bp
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
MMRRC Genetic QC Summary
The MMRRC Centers have developed a genetic QC pipeline using MiniMUGA array genotyping to provide additional information on strain backgrounds for MMRRC congenic and inbred strains. For more information on when data may be available, or to request genotyping for a strain of interest, please contact mmrrc@missouri.edu. Older strains may not have this information.
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R9207 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu.
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
068981-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.