Strain Name:
C57BL/6J-MtgxR0084Btlr/Mmmh
Stock Number:
038371-MU
Citation ID:
RRID:MMRRC_038371-MU
Other Names:
R0084 (G1), C57BL/6J-MtgxR0084Btlr
Major Collection:

Gene Information

Sbf2
Name: SET binding factor 2
Synonyms: SBF2, 4833411B01Rik, mMTMH1, B430219L04Rik, Mtmr13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319934
HGNC: HGNC:2135
Homologene: 41810
Slc6a5
Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 5
Synonyms: Glyt2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 104245
Homologene: 37901
Pax2
Name: paired box 2
Synonyms: Pax-2, Opdc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18504
HGNC: HGNC:8616
Homologene: 2968
Osbpl1a
Name: oxysterol binding protein-like 1A
Synonyms: LOC328902, G430090F17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 64291
Homologene: 84746
Zbtb43
Name: zinc finger and BTB domain containing 43
Synonyms: 1700010E06Rik, Zfp297b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 71834
Homologene: 8514
Hcrtr1
Name: hypocretin (orexin) receptor 1
Synonyms: OX1R
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 230777
HGNC: HGNC:4848
Homologene: 37492
Flnb
Name: filamin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Fbrsl1
Name: fibrosin-like 1
Synonyms: LOC381668, 2410025L10Rik, Gm29766
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 381668
Homologene: 45966
Anapc1
Name: anaphase promoting complex subunit 1
Synonyms: tsg24, Apc1, 2610021O03Rik, Mcpr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 17222
Homologene: 7414
Unc13d
Name: unc-13 homolog D
Synonyms: Munc13-4, 2610108D09Rik, Jinx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 70450
Homologene: 26714
Tirap
Name: toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
Synonyms: wyatt, MyD88-adapter-like, Mal, C130027E04Rik, Mal
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 117149
Homologene: 14285
Ncapd3
Name: non-SMC condensin II complex, subunit D3
Synonyms: 4632407J06Rik, 2810487N22Rik, B130055D15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 78658
VEGA: 9
Homologene: 41021
Ass1
Name: argininosuccinate synthetase 1
Synonyms: ASS, Ass-1, fold
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11898
HGNC: HGNC:758
Homologene: 6899
Tbc1d1
Name: TBC1 domain family, member 1
Synonyms: 1110062G02Rik, Nob1, Nobq1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 57915
Homologene: 56856
Nbeal2
Name: neurobeachin-like 2
Synonyms: 1110014F23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235627
Homologene: 86422
Btnl9
Name: butyrophilin-like 9
Synonyms: D330012D11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237754
Homologene: 68540
Acvr1
Name: activin A receptor, type 1
Synonyms: ActR-I, ALK2, Acvr, Acvrlk2, ActRIA, SKR1, Tsk7L, D330013D15Rik, Alk8, Alk-2, Acvr1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 11477
HGNC: HGNC:171
Homologene: 7
E4f1
Name: E4F transcription factor 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13560
VEGA: 17
HGNC: HGNC:3121
Homologene: 3259
Map4k3
Name: mitogen-activated protein kinase kinase kinase kinase 3
Synonyms: 9530052P13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 225028
VEGA: 17
HGNC: HGNC:6865
Homologene: 2683
Rhob
Name: ras homolog family member B
Synonyms: Arhb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11852
VEGA: 12
HGNC: HGNC:668
Homologene: 68377
Ercc5
Name: excision repair cross-complementing rodent repair deficiency, complementation group 5
Synonyms: Xpg
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 22592
HGNC: HGNC:3437
Homologene: 133551
Ttn
Name: titin
Synonyms: connectin, L56, mdm, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, 2310074I15Rik, 2310057K23Rik, D330041I19Rik, shru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 22138
Homologene: 130650
Zfp646
Name: zinc finger protein 646
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 233905
Homologene: 8802
Lmntd1
Name: lamin tail domain containing 1
Synonyms: Lmna-rs1, 4933403M22Rik, Ifltd1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 74071
Homologene: 69453
Scube3
Name: signal peptide, CUB domain, EGF-like 3
Synonyms: D030038I21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 268935
Homologene: 65059
Cntn1
Name: contactin 1
Synonyms: CNTN, F3cam, usl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 12805
HGNC: HGNC:2171
Homologene: 7274
Ppfia4
Name: protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Synonyms: 1110008G13Rik, LOC100042382, Liprin-alpha4, Gm3812
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 68507
HGNC: HGNC:9248
Homologene: 66200
Ifi30
Name: interferon gamma inducible protein 30
Synonyms: lysosomal thio reductase IP30 precursor, IP30, GILT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 65972
VEGA: 8
HGNC: HGNC:5398
Homologene: 38171
AI182371
Name: expressed sequence AI182371
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 98870
Homologene: 87268
Bpifb2
Name: BPI fold containing family B, member 2
Synonyms: 2310034L21Rik, 2310069A01Rik, Bpil1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 66557
Homologene: 11884
Spock3
Name: sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
Synonyms: testican 3, 2900045C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72902
Homologene: 9662
Apba1
Name: amyloid beta (A4) precursor protein binding, family A, member 1
Synonyms: X11alpha, Lin-10, X11, Mint1, Mint, 6430513E09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 319924
VEGA: 19
HGNC: HGNC:578
Homologene: 897
Abcc9
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms: SUR2B, SUR2A, Sur2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 20928
HGNC: HGNC:60
Homologene: 56521
Dcaf11
Name: DDB1 and CUL4 associated factor 11
Synonyms: 0710008A13Rik, GLO14, D14Ucla1, Wdr23
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 28199
Homologene: 11886
Abca8a
Name: ATP-binding cassette, sub-family A (ABC1), member 8a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 217258
HGNC: HGNC:38
Homologene: 131160
Acpp
Name: acid phosphatase, prostate
Synonyms: PAP, A030005E02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56318
HGNC: HGNC:125
Homologene: 55552
Adgb
Name: androglobin
Synonyms: 9130014G24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215772
Homologene: 100289
Spag16
Name: sperm associated antigen 16
Synonyms: Pf20, 4930524F24Rik, 4930585K05Rik, Wdr29, 4921511D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 66722
Homologene: 11572
Pam
Name: peptidylglycine alpha-amidating monooxygenase
Synonyms: PHM
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 18484
HGNC: HGNC:8596
Homologene: 37369
Slc28a2b
Name: solute carrier family 28 member 2b
Synonyms: Gm14085
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 381417
Ovol2
Name: ovo like zinc finger 2
Synonyms: M-OVO-B, M-OVO-A, M-OVO, 1810007D21Rik, Ovol2, Zfp339, movo2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 107586
Homologene: 10930
Tshz2
Name: teashirt zinc finger family member 2
Synonyms: Mtsh2, Sdccag33l, 2900073F20Rik, Zfp218, teashirt2, Tsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 228911
Homologene: 35258
Cpa3
Name: carboxypeptidase A3, mast cell
Synonyms: MC-CPA, mMC-CPA, mast cell carboxypeptidase A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12873
HGNC: HGNC:2298
Homologene: 122138
Spata16
Name: spermatogenesis associated 16
Synonyms: spermatogenesis-related protein, Nyd-sp12, 4930503K02Rik, 4921511F01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 70862
Homologene: 49974
Pik3ca
Name: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
Synonyms: p110alpha, caPI3K, 6330412C24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 18706
HGNC: HGNC:8975
Homologene: 21249
Ndufb5
Name: NADH:ubiquinone oxidoreductase subunit B5
Synonyms: 0610007D05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 66046
HGNC: HGNC:7700
Homologene: 31093
Moxd2
Name: monooxygenase, DBH-like 2
Synonyms: Dbhl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 194357
Homologene: 77226
Tpk1
Name: thiamine pyrophosphokinase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 29807
Homologene: 6960
4931417E11Rik
Name: RIKEN cDNA 4931417E11 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 66740
Homologene: 75225
Scgb2b2
Name: secretoglobin, family 2B, member 2
Synonyms: Abpe, Abpbg2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 381970
Homologene: 83171
Htatip2
Name: HIV-1 Tat interactive protein 2
Synonyms: TIP30
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 53415
Homologene: 4676
Olfr517
Name: olfactory receptor 517
Synonyms: GA_x6K02T2PBJ9-11199311-11198367, MOR268-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258136
Homologene: 79413
Paox
Name: polyamine oxidase (exo-N4-amino)
Synonyms: Pao, 2410012F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 212503
Homologene: 72096
Otogl
Name: otogelin-like
Synonyms: Gm6924
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 628870
Homologene: 46008
Heatr9
Name: HEAT repeat containing 9
Synonyms: Gm11435
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 629303
Homologene: 51895
Prkch
Name: protein kinase C, eta
Synonyms: Pkch
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 18755
HGNC: HGNC:9403
Homologene: 84384
Serpina1f
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1F
Synonyms: epserin, 0610012A11Rik, Serpina2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 68348
Homologene: 87037
Gm9848
Name: predicted gene 9848
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Ly6g2
Name: lymphocyte antigen 6 complex, locus G2
Synonyms: BC025446
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223631
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 44,175,976 bp
  • A to G, chromosome 1 at 69,996,839 bp
  • A to G, chromosome 1 at 97,896,049 bp
  • G to T, chromosome 1 at 134,299,426 bp
  • A to T, chromosome 2 at 31,514,819 bp
  • A to T, chromosome 2 at 33,453,984 bp
  • A to G, chromosome 2 at 35,085,702 bp
  • A to G, chromosome 2 at 58,458,883 bp
  • A to T, chromosome 2 at 76,872,699 bp
  • A to G, chromosome 2 at 122,522,833 bp
  • G to A, chromosome 2 at 128,623,966 bp
  • G to T, chromosome 2 at 144,305,888 bp
  • A to T, chromosome 2 at 153,891,091 bp
  • A to G, chromosome 2 at 169,884,366 bp
  • T to C, chromosome 3 at 20,242,101 bp
  • A to G, chromosome 3 at 26,667,410 bp
  • T to C, chromosome 3 at 32,462,788 bp
  • T to C, chromosome 3 at 32,737,203 bp
  • T to A, chromosome 4 at 130,137,266 bp
  • T to C, chromosome 5 at 64,324,454 bp
  • A to G, chromosome 5 at 110,379,515 bp
  • T to C, chromosome 6 at 40,879,408 bp
  • C to A, chromosome 6 at 43,346,829 bp
  • A to T, chromosome 6 at 73,468,935 bp
  • A to G, chromosome 6 at 142,658,551 bp
  • G to A, chromosome 6 at 145,404,528 bp
  • A to T, chromosome 7 at 31,303,616 bp
  • G to A, chromosome 7 at 49,759,672 bp
  • A to C, chromosome 7 at 49,930,013 bp
  • A to T, chromosome 7 at 108,868,800 bp
  • A to T, chromosome 7 at 110,442,366 bp
  • T to A, chromosome 7 at 127,881,304 bp
  • C to T, chromosome 7 at 140,132,446 bp
  • A to C, chromosome 8 at 63,143,929 bp
  • A to T, chromosome 8 at 70,764,545 bp
  • A to G, chromosome 9 at 27,056,111 bp
  • G to T, chromosome 9 at 35,189,162 bp
  • A to T, chromosome 9 at 104,314,365 bp
  • A to G, chromosome 9 at 110,643,710 bp
  • T to C, chromosome 10 at 10,396,344 bp
  • A to C, chromosome 10 at 107,901,341 bp
  • A to T, chromosome 11 at 49,178,779 bp
  • A to T, chromosome 11 at 83,512,895 bp
  • A to G, chromosome 11 at 110,036,597 bp
  • C to T, chromosome 11 at 116,063,831 bp
  • G to A, chromosome 12 at 8,499,107 bp
  • T to C, chromosome 12 at 73,697,987 bp
  • A to G, chromosome 12 at 103,693,588 bp
  • A to T, chromosome 13 at 113,108,242 bp
  • A to G, chromosome 14 at 7,935,979 bp
  • C to T, chromosome 14 at 55,569,243 bp
  • T to A, chromosome 15 at 75,217,775 bp
  • A to T, chromosome 15 at 92,317,917 bp
  • T to C, chromosome 17 at 24,444,082 bp
  • T to A, chromosome 17 at 28,162,961 bp
  • T to C, chromosome 17 at 80,655,914 bp
  • T to C, chromosome 18 at 12,757,612 bp
  • T to C, chromosome 19 at 23,912,497 bp
  • T to A, chromosome 19 at 44,818,435 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0084 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038371-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.