Strain Name:
C57BL/6J-MtgxR0143Btlr/Mmmh
Stock Number:
038428-MU
Citation ID:
RRID:MMRRC_038428-MU
Other Names:
R0143 (G1), C57BL/6J-MtgxR0143Btlr
Major Collection:

Gene Information

Cdh3
Name: cadherin 3
Synonyms: Cadp, Pcad, P-cadherin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12560
HGNC: HGNC:1762
Homologene: 20425
Notch2
Name: notch 2
Synonyms: Motch B, N2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18129
HGNC: HGNC:7882
Homologene: 7865
Phf20
Name: PHD finger protein 20
Synonyms: 6820402O20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228829
Homologene: 9507
Plcb4
Name: phospholipase C, beta 4
Synonyms: A930039J07Rik, C230058B11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18798
HGNC: HGNC:9059
Homologene: 8471
Tnpo3
Name: transportin 3
Synonyms: C430013M08Rik, D6Ertd313e, 5730544L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 320938
Homologene: 40848
Arhgef12
Name: Rho guanine nucleotide exchange factor (GEF) 12
Synonyms: 2310014B11Rik, LARG
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 69632
VEGA: 9
Homologene: 9088
Zdbf2
Name: zinc finger, DBF-type containing 2
Synonyms: 9330107J05Rik, 4930431J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 73884
Homologene: 52868
Dtx4
Name: deltex 4, E3 ubiquitin ligase
Synonyms: RNF155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 207521
VEGA: 19
Homologene: 27781
Lgals9
Name: lectin, galactose binding, soluble 9
Synonyms: Lgals5, galectin-9, gal-9, LGALS35
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16859
Homologene: 134662
Bbx
Name: bobby sox HMG box containing
Synonyms: 5530401J07Rik, 5730403O13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70508
Homologene: 10634
Ireb2
Name: iron responsive element binding protein 2
Synonyms: D9Ertd85e, Irp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 64602
VEGA: 9
HGNC: HGNC:6115
Homologene: 11280
Top3b
Name: topoisomerase (DNA) III beta
Synonyms: Topo III beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 21976
Homologene: 2923
Zfp462
Name: zinc finger protein 462
Synonyms: 9430078C22Rik, Gt4-2, Zfpip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 242466
Homologene: 41430
Stat3
Name: signal transducer and activator of transcription 3
Synonyms: Aprf, 1110034C02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 20848
Homologene: 7960
Ube4b
Name: ubiquitination factor E4B
Synonyms: 4930551I19Rik, Ufd2p, D4Bwg0973e, UFD2a, UFD2, 4933406G05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 63958
Homologene: 107623
Cog7
Name: component of oligomeric golgi complex 7
Synonyms: 5630400E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233824
Homologene: 33431
Tiam1
Name: T cell lymphoma invasion and metastasis 1
Synonyms: D16Ium10, D16Ium10e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 21844
Homologene: 2443
Ddx39
Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
Synonyms: BAT1, 2610307C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 68278
Homologene: 68487
Traf3
Name: TNF receptor-associated factor 3
Synonyms: CD40bp, CAP-1, LAP1, CRAF1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 22031
Homologene: 7981
Poldip3
Name: polymerase (DNA-directed), delta interacting protein 3
Synonyms: 1110008P04Rik, PDIP46
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 73826
Homologene: 13007
B3galt2
Name: UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 26878
HGNC: HGNC:917
Homologene: 74512
Rbms2
Name: RNA binding motif, single stranded interacting protein 2
Synonyms: Scr3, 2610315E04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 56516
VEGA: 10
HGNC: HGNC:9909
Homologene: 37706
Hnrnpl
Name: heterogeneous nuclear ribonucleoprotein L
Synonyms: D830027H13Rik, Hnrpl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 15388
HGNC: HGNC:5045
Homologene: 1174
Pex5
Name: peroxisomal biogenesis factor 5
Synonyms: ESTM1, PTS1R, peroxisome biogenesis factor 5, Pxr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 19305
HGNC: HGNC:9719
Homologene: 270
Ankrd34b
Name: ankyrin repeat domain 34B
Synonyms: 6430502M16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218440
Homologene: 18450
Zfp81
Name: zinc finger protein 81
Synonyms: C330034P10Rik, Zfp78, D330034E10Rik, KRAB13, Hszfp36
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 224694
Homologene: 138633
Usp8
Name: ubiquitin specific peptidase 8
Synonyms: Ubpy
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 84092
Homologene: 3782
Trim33
Name: tripartite motif-containing 33
Synonyms: 8030451N04Rik, ectodermin, Ecto, Tif1g
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 94093
Homologene: 9296
Tnrc6c
Name: trinucleotide repeat containing 6C
Synonyms: 9930033H14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217351
Homologene: 23137
Zfp345
Name: zinc finger protein 345
Synonyms: OTTMUSG00000015743
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 545471
Homologene: 134546
Mex3a
Name: mex3 RNA binding family member A
Synonyms: Rkhd4, 2700083E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 72640
Homologene: 18950
Dsg3
Name: desmoglein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 13512
VEGA: 18
HGNC: HGNC:3050
Homologene: 55513
Zfp830
Name: zinc finger protein 830
Synonyms: Ccdc16, 2410003C20Rik, Omcg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66983
Homologene: 41655
Lrp1
Name: low density lipoprotein receptor-related protein 1
Synonyms: A2mr, b2b1554Clo, CD91
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 16971
HGNC: HGNC:6692
Homologene: 1744
Mep1b
Name: meprin 1 beta
Synonyms: Mep-1b, meprin beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 17288
VEGA: 18
HGNC: HGNC:7020
Homologene: 48382
Hivep2
Name: human immunodeficiency virus type I enhancer binding protein 2
Synonyms: MIBP1, Gm20114, Shn-2, Schnurri-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 15273
HGNC: HGNC:4921
Homologene: 4900
Cul9
Name: cullin 9
Synonyms: 1810035I07Rik, Parc
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 78309
Homologene: 56696
Fhad1
Name: forkhead-associated (FHA) phosphopeptide binding domain 1
Synonyms: 2900090M10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329977
Homologene: 77947
Slc35b2
Name: solute carrier family 35, member B2
Synonyms: PAPST1, 1110003M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 73836
VEGA: 17
Homologene: 24504
Cyp4b1
Name: cytochrome P450, family 4, subfamily b, polypeptide 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 13120
HGNC: HGNC:2644
Homologene: 128045
Krt73
Name: keratin 73
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 223915
Homologene: 27875
Ttc38
Name: tetratricopeptide repeat domain 38
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 239570
Homologene: 41208
Henmt1
Name: HEN1 methyltransferase homolog 1 (Arabidopsis)
Synonyms: 4921515J06Rik, Hen1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 66715
Homologene: 32638
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12268
Homologene: 36030
Igsf3
Name: immunoglobulin superfamily, member 3
Synonyms: 2810035F16Rik, 4833439O17Rik, 1700016K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 78908
HGNC: HGNC:5950
Homologene: 1182
Prss1
Name: protease, serine 1 (trypsin 1)
Synonyms: Try-1, Trygn16, PRSS1, Try1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 114228
Homologene: 88408
Dennd4b
Name: DENN/MADD domain containing 4B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229541
Homologene: 28281
Polg2
Name: polymerase (DNA directed), gamma 2, accessory subunit
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 50776
HGNC: HGNC:9180
Homologene: 5221
Fes
Name: feline sarcoma oncogene
Synonyms: c-fes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 14159
HGNC: HGNC:3657
Homologene: 37563
Cacna1e
Name: calcium channel, voltage-dependent, R type, alpha 1E subunit
Synonyms: Cav2.3, Cchra1, alpha1E
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12290
HGNC: HGNC:1392
Homologene: 20185
Gm5828
Name: predicted gene 5828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 545306
Retreg2
Name: reticulophagy regulator family member 2
Synonyms: MGC47289, Fam134a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227298
Homologene: 11507
Tor1aip2
Name: torsin A interacting protein 2
Synonyms: 15kDa, LULL1, Ifrg15, 1110020D10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 240832
Homologene: 17028
Pex16
Name: peroxisomal biogenesis factor 16
Synonyms: peroxisome biogenesis factor 16
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18633
HGNC: HGNC:8857
Homologene: 3537
Hck
Name: hemopoietic cell kinase
Synonyms: Bmk, Hck-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15162
HGNC: HGNC:4840
Homologene: 20489
Ncf1
Name: neutrophil cytosolic factor 1
Synonyms: NADPH oxidase subunit (47kDa), p47phox, Ncf-1, NOXO2, p47phox
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 17969
HGNC: HGNC:7660
Homologene: 30964
Prrt4
Name: proline-rich transmembrane protein 4
Synonyms: D330027H18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 101359
Homologene: 46116
Isoc2a
Name: isochorismatase domain containing 2a
Synonyms: Isoc2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 664994
Homologene: 86122
Dpy19l3
Name: dpy-19-like 3 (C. elegans)
Synonyms: 9330164H19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233115
Homologene: 18692
Olfr491
Name: olfactory receptor 491
Synonyms: MOR204-11, GA_x6K02T2PBJ9-10646917-10647849
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258731
Homologene: 128150
Mmp13
Name: matrix metallopeptidase 13
Synonyms: Clg, Mmp1, Collagenase-3, collagenase-1, MMP-13, interstitial collagenase
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 17386
VEGA: 9
HGNC: HGNC:7159
Homologene: 20548
Slc6a15
Name: solute carrier family 6 (neurotransmitter transporter), member 15
Synonyms: v7-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 103098
VEGA: 10
Homologene: 18163
Dusp18
Name: dual specificity phosphatase 18
Synonyms: DUSP20, DSP18, 4930527G07Rik, LMWDSP20
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 75219
Homologene: 34984
Gsdma
Name: gasdermin A
Synonyms: Gsdma1, H312E, Gsdm1, Gsdm
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 57911
Homologene: 10962
Tpsab1
Name: tryptase alpha/beta 1
Synonyms: MMCP-7, Mcpt7, Mcp-7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 100503895
Olfr63
Name: olfactory receptor 63
Synonyms: M4, MOR267-1, GA_x6K02T2NTC5-9778-8828
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 258939
HGNC: HGNC:8174
Homologene: 130665
Spdya
Name: speedy/RINGO cell cycle regulator family, member A
Synonyms: speedy A1, 4930548B21Rik, 4921517J08Rik, Spdy1, speedy A2, speedy/ringo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 70891
Homologene: 16357
Ablim3
Name: actin binding LIM protein family, member 3
Synonyms: D930036B08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 319713
VEGA: 18
Homologene: 69175
Olfr1505
Name: olfactory receptor 1505
Synonyms: GA_x6K02T2RE5P-4250267-4251217, MOR211-10_i, MOR211-4P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258151
Homologene: 17394
Ankrd1
Name: ankyrin repeat domain 1 (cardiac muscle)
Synonyms: Crap, CARP, Alrp, MARP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 107765
VEGA: 19
Homologene: 8289
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to C, chromosome 1 at 16,768,355 bp
  • A to T, chromosome 1 at 63,308,074 bp
  • A to G, chromosome 1 at 75,146,430 bp
  • A to T, chromosome 1 at 143,647,334 bp
  • A to T, chromosome 1 at 154,448,947 bp
  • A to T, chromosome 1 at 156,059,548 bp
  • G to A, chromosome 2 at 92,380,457 bp
  • C to A, chromosome 2 at 126,755,089 bp
  • T to A, chromosome 2 at 135,976,211 bp
  • T to A, chromosome 2 at 150,472,555 bp
  • T to A, chromosome 2 at 153,134,220 bp
  • GTGTTTGTTTGTTTGTTTGTTTGTTT to GTGTTTGTTTGTTTGTTTGTTTGTTTGTTTGTTT, chromosome 2 at 156,287,770 bp
  • G to T, chromosome 3 at 88,536,255 bp
  • A to T, chromosome 3 at 90,272,364 bp
  • A to G, chromosome 3 at 98,146,117 bp
  • T to C, chromosome 3 at 101,435,601 bp
  • T to A, chromosome 3 at 103,352,101 bp
  • A to T, chromosome 3 at 108,953,802 bp
  • C to A, chromosome 4 at 55,023,402 bp
  • C to T, chromosome 4 at 115,635,874 bp
  • C to A, chromosome 4 at 141,929,646 bp
  • C to T, chromosome 4 at 149,355,457 bp
  • G to T, chromosome 5 at 134,227,137 bp
  • C to G, chromosome 6 at 29,170,671 bp
  • A to G, chromosome 6 at 29,565,652 bp
  • A to G, chromosome 6 at 41,463,588 bp
  • A to T, chromosome 6 at 124,398,489 bp
  • T to C, chromosome 7 at 4,891,332 bp
  • T to C, chromosome 7 at 28,814,192 bp
  • T to C, chromosome 7 at 35,714,215 bp
  • A to C, chromosome 7 at 80,383,895 bp
  • A to G, chromosome 7 at 108,316,995 bp
  • A to T, chromosome 7 at 121,951,164 bp
  • T to C, chromosome 8 at 83,720,550 bp
  • T to C, chromosome 8 at 106,511,225 bp
  • T to C, chromosome 9 at 7,276,558 bp
  • T to C, chromosome 9 at 43,005,594 bp
  • T to C, chromosome 9 at 54,885,909 bp
  • T to C, chromosome 10 at 14,129,355 bp
  • T to G, chromosome 10 at 103,418,068 bp
  • A to G, chromosome 10 at 127,593,942 bp
  • T to A, chromosome 10 at 128,137,954 bp
  • C to T, chromosome 11 at 3,897,243 bp
  • T to A, chromosome 11 at 78,963,535 bp
  • A to G, chromosome 11 at 82,765,168 bp
  • A to C, chromosome 11 at 98,666,254 bp
  • A to T, chromosome 11 at 100,895,156 bp
  • C to A, chromosome 11 at 106,777,526 bp
  • A to C, chromosome 11 at 117,752,985 bp
  • T to A, chromosome 12 at 111,261,576 bp
  • A to G, chromosome 13 at 92,439,760 bp
  • G to A, chromosome 15 at 83,127,943 bp
  • T to C, chromosome 15 at 85,853,719 bp
  • T to A, chromosome 15 at 101,800,773 bp
  • T to C, chromosome 16 at 16,883,525 bp
  • C to T, chromosome 16 at 50,280,392 bp
  • A to T, chromosome 16 at 89,898,200 bp
  • T to A, chromosome 17 at 25,343,444 bp
  • T to C, chromosome 17 at 33,269,497 bp
  • G to A, chromosome 17 at 33,335,121 bp
  • G to A, chromosome 17 at 34,734,219 bp
  • A to G, chromosome 17 at 45,565,088 bp
  • T to C, chromosome 17 at 46,526,410 bp
  • T to A, chromosome 17 at 71,558,640 bp
  • T to C, chromosome 18 at 20,536,825 bp
  • T to C, chromosome 18 at 21,095,107 bp
  • A to T, chromosome 18 at 61,855,217 bp
  • G to A, chromosome 19 at 12,486,482 bp
  • A to C, chromosome 19 at 13,919,250 bp
  • G to A, chromosome 19 at 36,119,313 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0143 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038428-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.