Beutler Mutagenetix

Strain Name:
C57BL/6J-MtgxR0157Btlr/Mmmh
Stock Number:
038437-MU
Citation ID:
RRID:MMRRC_038437-MU
Other Names:
R0157 (G1), C57BL/6J-MtgxR0157Btlr
Major Collection:

Gene Information

Arhgef7
Name: Rho guanine nucleotide exchange factor (GEF7)
Synonyms: cool-1, Pak interacting exchange factor, betaPix, p85SPR, PIX, Cool, betaPix-c, betaPix-b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 54126
Homologene: 2895
Chd7
Name: chromodomain helicase DNA binding protein 7
Synonyms: WBE1, Flo, GENA 60, GENA 47, Whi, Mt, Gena 52, Edy, Dz, A730019I05Rik, Todo, Obt, Cyn, Cycn, Lda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 320790
Homologene: 19067
Pzp
Name: PZP, alpha-2-macroglobulin like
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 11287
HGNC: null
Homologene: 104112
Lin7c
Name: lin-7 homolog C (C. elegans)
Synonyms: LIN-7-C, Veli3, D2Ertd520e, 9130007B12Rik, LIN-7C, Lin7c, MALS-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22343
Homologene: 22649
Atad5
Name: ATPase family, AAA domain containing 5
Synonyms: C130052G03Rik, LOC237877
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237877
Homologene: 32611
Yeats2
Name: YEATS domain containing 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 208146
VEGA: 16
Homologene: 9967
Prpf4b
Name: pre-mRNA processing factor 4B
Synonyms: Prp4, Prp4k, Prpk
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 19134
VEGA: 13
Homologene: 134085
Chd9
Name: chromodomain helicase DNA binding protein 9
Synonyms: 9030205D12Rik, 1810014J18Rik, AD013, A330063D19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 109151
Homologene: 11844
Polr3a
Name: polymerase (RNA) III (DNA directed) polypeptide A
Synonyms: 9330175N20Rik, RPC1, RPC155
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 218832
VEGA: 14
Homologene: 5124
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
R3hdm2
Name: R3H domain containing 2
Synonyms: 1300003K24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 71750
Homologene: 8954
Cenpf
Name: centromere protein F
Synonyms: 6530404A22Rik, mitosin, Lek1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 108000
HGNC: HGNC:1857
Homologene: 22969
Zfp26
Name: zinc finger protein 26
Synonyms: mkr-3, Zfp70, Zfp81-rs1, 5033428C05Rik, Zfp-26, KRAB15
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22688
Homologene: 52318
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 239250
VEGA: 14
Homologene: 12986
Orc3
Name: origin recognition complex, subunit 3
Synonyms: Orc3l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 50793
HGNC: HGNC:8489
Homologene: 8225
Polr2e
Name: polymerase (RNA) II (DNA directed) polypeptide E
Synonyms: RPB5, XAP4, 25kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 66420
HGNC: HGNC:9192
Homologene: 2018
Pdcl
Name: phosducin-like
Synonyms: 1200011E13Rik, PhLP1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 67466
HGNC: HGNC:8770
Homologene: 38043
Tasor2
Name: transcription activation suppressor family member 2
Synonyms: BC016423, Fam208b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105203
VEGA: 13
Homologene: 26435
Mms22l
Name: MMS22-like, DNA repair protein
Synonyms: F730047E07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 212377
Homologene: 18874
Dnah7a
Name: dynein, axonemal, heavy chain 7A
Synonyms: Dnahc7, Dnahc7a, LOC381341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 627872
Homologene: 41287
Ckmt1
Name: creatine kinase, mitochondrial 1, ubiquitous
Synonyms: UbCKmit, mi-CK, Mt-CK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 12716
Homologene: 69058
Lamc1
Name: laminin, gamma 1
Synonyms: laminin B2, Lamb2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226519
HGNC: HGNC:6492
Homologene: 1724
Furin
Name: furin (paired basic amino acid cleaving enzyme)
Synonyms: Pcsk3, PACE, SPC1, 9130404I01Rik, Fur
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18550
HGNC: HGNC:8568
Homologene: 1930
Atp2b1
Name: ATPase, Ca++ transporting, plasma membrane 1
Synonyms: E130111D10Rik, 2810442I22Rik, PMCA1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 67972
VEGA: 10
HGNC: HGNC:814
Homologene: 55597
Gm9631
Name: predicted gene 9631
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 674842
Ensembl: null
VEGA: 11
HGNC: null
Homologene: null
Cul7
Name: cullin 7
Synonyms: p185, p193, 2510004L20Rik, C230011P08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 66515
Homologene: 56683
Mindy1
Name: MINDY lysine 48 deubiquitinase 1
Synonyms: 4930504E06Rik, 1810005H09Rik, cI-40, NF-E2 inducible protein, Fam63a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 75007
Homologene: 32409
Sidt2
Name: SID1 transmembrane family, member 2
Synonyms: CGI-40
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 214597
Homologene: 22943
Il20rb
Name: interleukin 20 receptor beta
Synonyms: LOC213208, Il20R2, Fndc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 213208
HGNC: HGNC:6004
Homologene: 86034
Cdk12
Name: cyclin-dependent kinase 12
Synonyms: D11Ertd752e, 1810022J16Rik, Crk7, Crkrs
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69131
Homologene: 128632
Pms1
Name: PMS1 homolog 1, mismatch repair system component
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 227099
HGNC: HGNC:9121
Homologene: 449
Sec31a
Name: Sec31 homolog A (S. cerevisiae)
Synonyms: 1810024J13Rik, Sec31l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 69162
Homologene: 42056
Alg8
Name: asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
Synonyms: LOC381903
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 381903
Homologene: 6931
Clec4d
Name: C-type lectin domain family 4, member d
Synonyms: mcl, Mpcl, Clecsf8, mMCL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 17474
Homologene: 7844
Steap3
Name: STEAP family member 3
Synonyms: pHyde, 1010001D01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 68428
Homologene: 10084
Pla2g4e
Name: phospholipase A2, group IVE
Synonyms: 2310026J01Rik, Pla2epsilon
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 329502
Homologene: 65339
Pmpcb
Name: peptidase (mitochondrial processing) beta
Synonyms: MPP11, MPPP52, 3110004O18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 73078
HGNC: HGNC:9119
Homologene: 3160
Hydin
Name: HYDIN, axonemal central pair apparatus protein
Synonyms: 4930545D19Rik, hy-3, hy3, 1700034M11Rik, hyrh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 244653
Homologene: 52118
Svep1
Name: sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
Synonyms: 1110021D17Rik, 4833413O10Rik, Polydom, D430029O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 64817
Homologene: 23386
Tecta
Name: tectorin alpha
Synonyms: Tctna, [a]-tectorin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 21683
Homologene: 3955
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Hoxc11
Name: homeobox C11
Synonyms: Hox-3.7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 109663
HGNC: HGNC:5123
Homologene: 130362
Slc22a29
Name: solute carrier family 22. member 29
Synonyms: D630002G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 236293
Homologene: 77136
Cdhr3
Name: cadherin-related family member 3
Synonyms: 1110049B09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 68764
VEGA: 12
Homologene: 45146
Pcdh10
Name: protocadherin 10
Synonyms: 6430521D13Rik, OL-pc, 6430703F07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18526
Homologene: 74967
Nlrp2
Name: NLR family, pyrin domain containing 2
Synonyms: Nalp2, PYPAF2, E330007A02Rik, Pan1, Nbs1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232827
Homologene: 56789
Sox21
Name: SRY (sex determining region Y)-box 21
Synonyms: Sox25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 223227
Homologene: 5143
Plcb2
Name: phospholipase C, beta 2
Synonyms: B230205M18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 18796
HGNC: HGNC:9055
Homologene: 20957
Ankrd7
Name: ankyrin repeat domain 7
Synonyms: 4930532L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 75196
Homologene: 35506
Pard3b
Name: par-3 family cell polarity regulator beta
Synonyms: 1810008K04Rik, 2010002N16Rik, Als2cr19, 2810455B10Rik, PAR3beta, PAR3B, PAR3L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 72823
Homologene: 35389
Taar2
Name: trace amine-associated receptor 2
Synonyms: Gpr58
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 209512
HGNC: HGNC:4514
Homologene: 110760
Gjd4
Name: gap junction protein, delta 4
Synonyms: Cx39, 9430022F06Rik, connexin 39
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 225152
VEGA: 18
Homologene: 17692
Myh3
Name: myosin, heavy polypeptide 3, skeletal muscle, embryonic
Synonyms: Myhse, Myhs-e, MyHC-emb
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 17883
HGNC: HGNC:7573
Homologene: 20553
Sema3d
Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
Synonyms: 4631426B19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 108151
Homologene: 23664
Arhgef4
Name: Rho guanine nucleotide exchange factor (GEF) 4
Synonyms: Asef, C230030N03Rik, 9330140K16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226970
HGNC: HGNC:684
Homologene: 49414
Csmd2
Name: CUB and Sushi multiple domains 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 329942
Homologene: 89034
Vwa5b1
Name: von Willebrand factor A domain containing 5B1
Synonyms: 4931403E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 75718
Homologene: 19431
Pkn1
Name: protein kinase N1
Synonyms: Pkn, F730027O18Rik, PAK1, Stk3, Prkcl1, PRK1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 320795
HGNC: HGNC:9405
Homologene: 48130
Qrich2
Name: glutamine rich 2
Synonyms: LOC217341
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 217341
Homologene: 12951
Arhgef26
Name: Rho guanine nucleotide exchange factor (GEF) 26
Synonyms: 8430436L14Rik, 4631416L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 622434
Homologene: 9204
F13b
Name: coagulation factor XIII, beta subunit
Synonyms: Cf-13b, Cf13b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 14060
HGNC: HGNC:3534
Homologene: 1512
Cacna2d4
Name: calcium channel, voltage-dependent, alpha 2/delta subunit 4
Synonyms: 5730412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 319734
Homologene: 26544
Bpifb6
Name: BPI fold containing family B, member 6
Synonyms: Bpil3, LOC228796
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228796
Homologene: 18375
BC028528
Name: cDNA sequence BC028528
Synonyms: L259
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229600
Homologene: 49773
Gm13083
Name: predicted gene 13083
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 279185
HGNC: null
Homologene: 133722
Pcolce
Name: procollagen C-endopeptidase enhancer protein
Synonyms: Astt2, Astt-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 18542
HGNC: HGNC:8738
Homologene: 1946
Gm4969
Name: predicted gene 4969
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243866
Homologene: 131804
Vmn1r173
Name: vomeronasal 1 receptor 173
Synonyms: Gm5892
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 545934
HGNC: null
Homologene: 79577
Zfp426
Name: zinc finger protein 426
Synonyms: KRAB1, Zfp68-rs1, 2900057C04Rik, Zfo61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235028
Homologene: 23435
Olfr1384
Name: olfactory receptor 1384
Synonyms: MOR256-23, GA_x6K02T2QP88-5922712-5921756
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258464
HGNC: null
Homologene: 74259
Olfr314
Name: olfactory receptor 314
Synonyms: MOR278-2, GA_x6K02T2NKPP-622179-621244
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 257917
Homologene: 133891
Adap2
Name: ArfGAP with dual PH domains 2
Synonyms: centaurin alpha 2, Centa2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 216991
Homologene: 10179
B130006D01Rik
Name: RIKEN cDNA B130006D01 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 320616
VEGA: 11
HGNC: null
Homologene: null
Asap2
Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Synonyms: LOC385250, 6530401G17Rik, Ddef2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 211914
HGNC: HGNC:2721
Homologene: 2888
Dab2
Name: disabled 2, mitogen-responsive phosphoprotein
Synonyms: 5730435J12Rik, p96, D15Wsu122e, D630005B22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 13132
HGNC: HGNC:2662
Homologene: 1026
Krtap21-1
Name: keratin associated protein 21-1
Synonyms: Krtap16-7, 1110017B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 170656
VEGA: 16
HGNC: null
Homologene: null
Ndufb10
Name: NADH:ubiquinone oxidoreductase subunit B10
Synonyms: 0610011B04Rik, 22kDa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 68342
HGNC: HGNC:7696
Homologene: 3343
Alk
Name: anaplastic lymphoma kinase
Synonyms: CD246, Tcrz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 11682
VEGA: 17
HGNC: HGNC:427
Homologene: 68387
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 34,806,394 bp
  • A to T, chromosome 1 at 53,195,037 bp
  • C to A, chromosome 1 at 53,706,668 bp
  • A to C, chromosome 1 at 62,211,633 bp
  • A to G, chromosome 1 at 120,227,649 bp
  • G to A, chromosome 1 at 139,503,847 bp
  • T to C, chromosome 1 at 153,262,607 bp
  • T to A, chromosome 1 at 189,652,359 bp
  • A to C, chromosome 2 at 37,352,177 bp
  • C to A, chromosome 2 at 109,895,169 bp
  • C to A, chromosome 2 at 118,718,541 bp
  • T to A, chromosome 2 at 120,170,181 bp
  • A to G, chromosome 2 at 121,363,041 bp
  • T to A, chromosome 2 at 153,903,966 bp
  • A to G, chromosome 3 at 45,379,701 bp
  • T to G, chromosome 3 at 62,380,971 bp
  • T to A, chromosome 3 at 95,292,732 bp
  • A to G, chromosome 3 at 95,884,968 bp
  • T to A, chromosome 4 at 8,833,759 bp
  • C to A, chromosome 4 at 24,588,224 bp
  • C to A, chromosome 4 at 34,607,130 bp
  • T to C, chromosome 4 at 58,069,830 bp
  • G to T, chromosome 4 at 128,521,911 bp
  • T to A, chromosome 4 at 138,604,879 bp
  • C to T, chromosome 4 at 143,615,796 bp
  • A to T, chromosome 5 at 12,508,137 bp
  • A to T, chromosome 5 at 21,742,952 bp
  • A to G, chromosome 5 at 100,382,754 bp
  • A to T, chromosome 5 at 137,610,479 bp
  • T to C, chromosome 6 at 18,866,540 bp
  • T to A, chromosome 6 at 119,312,424 bp
  • G to T, chromosome 6 at 123,267,136 bp
  • G to A, chromosome 6 at 128,523,976 bp
  • T to C, chromosome 7 at 5,308,770 bp
  • T to C, chromosome 7 at 19,107,020 bp
  • T to A, chromosome 7 at 23,702,397 bp
  • T to A, chromosome 7 at 80,398,200 bp
  • T to C, chromosome 7 at 97,388,442 bp
  • A to G, chromosome 8 at 11,785,812 bp
  • T to C, chromosome 8 at 83,692,820 bp
  • T to C, chromosome 8 at 91,008,836 bp
  • T to C, chromosome 8 at 110,300,010 bp
  • G to T, chromosome 9 at 20,437,870 bp
  • T to C, chromosome 9 at 20,471,136 bp
  • A to G, chromosome 9 at 42,375,011 bp
  • A to G, chromosome 9 at 45,939,267 bp
  • A to G, chromosome 9 at 100,473,079 bp
  • T to A, chromosome 10 at 23,941,491 bp
  • C to T, chromosome 10 at 80,036,781 bp
  • T to C, chromosome 10 at 98,999,947 bp
  • T to G, chromosome 10 at 127,471,989 bp
  • T to C, chromosome 11 at 49,513,773 bp
  • T to C, chromosome 11 at 58,787,059 bp
  • A to G, chromosome 11 at 67,082,909 bp
  • T to C, chromosome 11 at 80,089,817 bp
  • T to A, chromosome 11 at 80,165,701 bp
  • T to C, chromosome 11 at 95,726,385 bp
  • A to G, chromosome 11 at 98,249,776 bp
  • T to C, chromosome 11 at 107,074,658 bp
  • T to A, chromosome 11 at 116,441,395 bp
  • C to T, chromosome 11 at 118,127,171 bp
  • G to A, chromosome 11 at 121,943,540 bp
  • T to A, chromosome 12 at 21,206,325 bp
  • T to C, chromosome 12 at 33,061,650 bp
  • C to A, chromosome 13 at 3,575,550 bp
  • T to C, chromosome 13 at 34,884,031 bp
  • T to C, chromosome 14 at 24,479,186 bp
  • A to T, chromosome 14 at 110,749,932 bp
  • G to A, chromosome 14 at 118,235,942 bp
  • T to C, chromosome 15 at 6,429,827 bp
  • A to G, chromosome 15 at 102,955,001 bp
  • A to C, chromosome 16 at 20,221,677 bp
  • A to G, chromosome 16 at 89,403,542 bp
  • T to C, chromosome 17 at 24,724,244 bp
  • T to A, chromosome 17 at 46,653,835 bp
  • T to A, chromosome 17 at 71,949,845 bp
  • T to C, chromosome 18 at 9,280,549 bp
  • C to T, chromosome 19 at 8,162,742 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0157 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038437-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.