Strain Name:
C57BL/6J-MtgxR0320Btlr/Mmmh
Stock Number:
038530-MU
Citation ID:
RRID:MMRRC_038530-MU
Other Names:
R0320 (G1), C57BL/6J-MtgxR0320Btlr
Major Collection:

Gene Information

Setd5
Name: SET domain containing 5
Synonyms: 2900045N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 72895
Homologene: 12485
Ints6
Name: integrator complex subunit 6
Synonyms: Notch2l, DICE1, 2900075H24Rik, Ddx26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 18130
VEGA: 14
Homologene: 8121
Dop1b
Name: DOP1 leucine zipper like protein B
Synonyms: 2610510B01Rik, Dopey2, 0610038M01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 70028
VEGA: 16
HGNC: HGNC:1291
Homologene: 21068
Prdm2
Name: PR domain containing 2, with ZNF domain
Synonyms: 4833427P12Rik, LOC381568, E330024L24Rik, Riz, KMT8, Riz1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 110593
HGNC: HGNC:9347
Homologene: 40822
Vcl
Name: vinculin
Synonyms: metavinculin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 22330
VEGA: 14
Homologene: 7594
Kdm5a
Name: lysine (K)-specific demethylase 5A
Synonyms: Rbbp2, Jarid1a, RBP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 214899
HGNC: HGNC:9886
Homologene: 3419
Ctc1
Name: CTS telomere maintenance complex component 1
Synonyms: 1500010J02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 68964
Homologene: 11830
Bptf
Name: bromodomain PHD finger transcription factor
Synonyms: 9430093H17Rik, Falz
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 207165
HGNC: HGNC:3581
Homologene: 114397
Scaf8
Name: SR-related CTD-associated factor 8
Synonyms: Rbm16, A930036P18Rik, A630086M08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106583
VEGA: 17
Homologene: 8928
Parp4
Name: poly (ADP-ribose) polymerase family, member 4
Synonyms: Adprtl1, VPARP, C030027K23Rik, E230037B21Rik, VAULT3, PH5P, p193
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 328417
HGNC: HGNC:271
Homologene: 124423
Mcm10
Name: minichromosome maintenance 10 replication initiation factor
Synonyms: C330019M07Rik, 2410041F14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 70024
Homologene: 41275
Abcb8
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 8
Synonyms: 4833412N02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 74610
HGNC: HGNC:49
Homologene: 5203
St7l
Name: suppression of tumorigenicity 7-like
Synonyms: St7r
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229681
Homologene: 14910
Adam8
Name: a disintegrin and metallopeptidase domain 8
Synonyms: CD156, MS2, E430039A18Rik, CD156a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 11501
HGNC: HGNC:215
Homologene: 74384
Cit
Name: citron
Synonyms: C030025P15Rik, citron kinase, Cit-k, citron-N, CRIK-SK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 12704
HGNC: HGNC:1985
Homologene: 21404
Vps13b
Name: vacuolar protein sorting 13B
Synonyms: 2310042E16Rik, Coh1, 1810042B05Rik, C330002D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 666173
VEGA: 15
HGNC: HGNC:2183
Homologene: 49516
Nrip1
Name: nuclear receptor interacting protein 1
Synonyms: RIP140, 8430438I05Rik, 6030458L20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 268903
HGNC: HGNC:8001
Homologene: 2606
Eif5a
Name: eukaryotic translation initiation factor 5A
Synonyms: D19Wsu54e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 276770
HGNC: HGNC:3300
Homologene: 133803
Akap11
Name: A kinase (PRKA) anchor protein 11
Synonyms: 6330501D17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219181
HGNC: HGNC:369
Homologene: 8279
Flt3
Name: FMS-like tyrosine kinase 3
Synonyms: Flk2, wmfl, Flt-3, CD135, Flk-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 14255
HGNC: HGNC:3765
Homologene: 3040
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 12870
HGNC: HGNC:2295
Homologene: 75
Wnt16
Name: wingless-type MMTV integration site family, member 16
Synonyms: E130309I19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 93735
Homologene: 62175
Itgae
Name: integrin alpha E, epithelial-associated
Synonyms: alpha-E1, CD103
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16407
HGNC: HGNC:6147
Homologene: 113560
Aldh3b1
Name: aldehyde dehydrogenase 3 family, member B1
Synonyms: 1700001N19Rik, ALDH7, ALDH4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 67689
VEGA: 19
HGNC: HGNC:410
Homologene: 73890
Arhgap30
Name: Rho GTPase activating protein 30
Synonyms: 6030405P05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 226652
Homologene: 18766
Dnah17
Name: dynein, axonemal, heavy chain 17
Synonyms: LOC382552, 2810003K23Rik, Dnahcl1, Dnahc17
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 69926
HGNC: HGNC:2946
Homologene: 72102
Ralgps1
Name: Ral GEF with PH domain and SH3 binding motif 1
Synonyms: RALGEF2, 5830418G11Rik, RALGPS1A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241308
Homologene: 65163
9430007A20Rik
Name: RIKEN cDNA 9430007A20 gene
Synonyms: LOC381572
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 381572
Homologene: 28662
Dym
Name: dymeclin
Synonyms: C030019K18Rik, 4933427L07Rik, 1810041M12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 69190
VEGA: 18
Homologene: 69237
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546981
Homologene: 115466
Parp3
Name: poly (ADP-ribose) polymerase family, member 3
Synonyms: Adprt3, A930002C11Rik, Adprtl3, PARP-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235587
HGNC: HGNC:273
Homologene: 4005
Cpd
Name: carboxypeptidase D
Synonyms: D830034L15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12874
HGNC: HGNC:2301
Homologene: 999
C4b
Name: complement component 4B (Chido blood group)
Synonyms: C4, Ss
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 12268
Homologene: 36030
Col4a1
Name: collagen, type IV, alpha 1
Synonyms: Del(8)Bru44H, Raw, Col4a-1, alpha1(IV) collagen, Svc, Del(8)44H, Bru
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 12826
HGNC: HGNC:2202
Homologene: 20437
Tigd4
Name: tigger transposable element derived 4
Synonyms: C130063O11Rik, Tigd4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 403175
Homologene: 131124
Itga1
Name: integrin alpha 1
Synonyms: CD49A, E130012M19Rik, Vla1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 109700
VEGA: 13
HGNC: HGNC:6134
Homologene: 57137
Psd2
Name: pleckstrin and Sec7 domain containing 2
Synonyms: 6330404E20Rik, EFA6C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 74002
Homologene: 12522
Ofcc1
Name: orofacial cleft 1 candidate 1
Synonyms: Opo, ojoplano
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 218165
VEGA: 13
Homologene: 125376
Tmc3
Name: transmembrane channel-like gene family 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233424
Homologene: 45588
Itprid1
Name: ITPR interacting domain containing 1
Synonyms: Ccdc129, D530004J12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 232016
Homologene: 52344
Zfp788
Name: zinc finger protein 788
Synonyms: 2810426N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 67607
Homologene: 137363
3425401B19Rik
Name: RIKEN cDNA 3425401B19 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 100504518
VEGA: 14
Homologene: 54908
Mcam
Name: melanoma cell adhesion molecule
Synonyms: CD146, 1-gicerin, s-gicerin, Muc18, s-endo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 84004
HGNC: HGNC:6934
Homologene: 4742
Lmx1a
Name: LIM homeobox transcription factor 1 alpha
Synonyms: shaker short-tail, Lmx1.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 110648
HGNC: HGNC:6653
Homologene: 24921
A430110L20Rik
Name: RIKEN cDNA A430110L20 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329307
Stom
Name: stomatin
Synonyms: stomatin, Epb7.2, protein 7.2b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 13830
HGNC: HGNC:3383
Homologene: 81681
Atp8b4
Name: ATPase, class I, type 8B, member 4
Synonyms: Im
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241633
Homologene: 133162
Pilrb1
Name: paired immunoglobin-like type 2 receptor beta 1
Synonyms: Pilrb, Fdact
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 170741
Homologene: 114502
Calu
Name: calumenin
Synonyms: 9530075H20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 12321
HGNC: HGNC:1458
Homologene: 936
Ppm1n
Name: protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 232941
Homologene: 58958
Vmn1r168
Name: vomeronasal 1 receptor 168
Synonyms: Gm10659
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 100043101
Homologene: 122945
Olfr689
Name: olfactory receptor 689
Synonyms: GA_x6K02T2PBJ9-7942985-7943947, MOR40-3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258745
Homologene: 128074
Lrrc25
Name: leucine rich repeat containing 25
Synonyms: Mapa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 211228
Homologene: 51663
Abcb10
Name: ATP-binding cassette, sub-family B (MDR/TAP), member 10
Synonyms: ABC-me
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 56199
HGNC: HGNC:41
Homologene: 6474
Spsb4
Name: splA/ryanodine receptor domain and SOCS box containing 4
Synonyms: Ssb4, D030068E18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 211949
Homologene: 25315
Xirp1
Name: xin actin-binding repeat containing 1
Synonyms: mXin alpha, Cmya1, Xin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 22437
VEGA: 9
Homologene: 7998
Olfr382
Name: olfactory receptor 382
Synonyms: GA_x6K02T2P1NL-3676608-3675670, MOR135-14, MOR135-31_p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 258435
Homologene: 17252
Ccdc186
Name: coiled-coil domain containing 186
Synonyms: A630007B06Rik, 1810028B20Rik, Otg1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 213993
Homologene: 9963
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • C to T, chromosome 1 at 167,791,404 bp
  • T to A, chromosome 1 at 171,403,804 bp
  • T to G, chromosome 1 at 181,227,422 bp
  • A to T, chromosome 2 at 5,004,086 bp
  • A to T, chromosome 2 at 33,141,015 bp
  • C to T, chromosome 2 at 35,321,634 bp
  • A to G, chromosome 2 at 126,459,694 bp
  • T to C, chromosome 3 at 19,974,848 bp
  • T to A, chromosome 3 at 84,595,174 bp
  • T to A, chromosome 3 at 104,870,913 bp
  • A to T, chromosome 4 at 143,179,351 bp
  • A to T, chromosome 4 at 144,522,420 bp
  • T to C, chromosome 5 at 24,400,790 bp
  • C to A, chromosome 5 at 115,979,445 bp
  • G to A, chromosome 5 at 137,854,998 bp
  • A to T, chromosome 5 at 147,369,579 bp
  • T to G, chromosome 6 at 22,297,993 bp
  • C to A, chromosome 6 at 29,374,551 bp
  • T to C, chromosome 6 at 55,976,447 bp
  • A to G, chromosome 6 at 113,111,481 bp
  • T to C, chromosome 6 at 120,389,620 bp
  • A to G, chromosome 7 at 19,278,356 bp
  • G to A, chromosome 7 at 23,541,342 bp
  • C to T, chromosome 7 at 41,649,547 bp
  • A to C, chromosome 7 at 83,607,819 bp
  • C to A, chromosome 7 at 86,165,080 bp
  • A to T, chromosome 7 at 105,314,654 bp
  • C to A, chromosome 7 at 139,986,442 bp
  • C to T, chromosome 8 at 11,242,782 bp
  • T to C, chromosome 8 at 70,618,246 bp
  • C to T, chromosome 8 at 123,963,007 bp
  • T to A, chromosome 9 at 44,140,186 bp
  • T to A, chromosome 9 at 96,996,108 bp
  • T to A, chromosome 9 at 106,475,812 bp
  • C to A, chromosome 9 at 120,016,467 bp
  • T to A, chromosome 11 at 69,033,537 bp
  • G to T, chromosome 11 at 69,917,479 bp
  • A to G, chromosome 11 at 73,130,999 bp
  • T to G, chromosome 11 at 73,516,924 bp
  • T to C, chromosome 11 at 76,840,447 bp
  • A to T, chromosome 11 at 107,072,819 bp
  • A to G, chromosome 11 at 118,052,674 bp
  • G to C, chromosome 13 at 40,206,696 bp
  • A to G, chromosome 13 at 114,977,594 bp
  • C to T, chromosome 14 at 20,985,624 bp
  • T to C, chromosome 14 at 32,662,614 bp
  • T to C, chromosome 14 at 56,588,496 bp
  • A to T, chromosome 14 at 62,707,635 bp
  • T to C, chromosome 14 at 78,513,379 bp
  • A to T, chromosome 15 at 35,674,828 bp
  • T to C, chromosome 16 at 76,292,363 bp
  • C to A, chromosome 16 at 93,810,147 bp
  • T to C, chromosome 17 at 3,178,255 bp
  • C to A, chromosome 17 at 34,733,161 bp
  • C to T, chromosome 18 at 35,979,644 bp
  • T to A, chromosome 18 at 75,199,262 bp
  • T to C, chromosome 19 at 3,918,999 bp
  • T to C, chromosome 19 at 56,801,996 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0320 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038530-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.