Strain Name:
C57BL/6J-MtgxR0356Btlr/Mmmh
Stock Number:
038562-MU
Citation ID:
RRID:MMRRC_038562-MU
Other Names:
R0356 (G1), C57BL/6J-MtgxR0356Btlr
Major Collection:

Gene Information

Trim32
Name: tripartite motif-containing 32
Synonyms: 3f3, 1810045E12Rik, Zfp117, BBS11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 69807
Homologene: 36327
Itga8
Name: integrin alpha 8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241226
HGNC: HGNC:6144
Homologene: 37396
Cbfa2t2
Name: CBFA2/RUNX1 translocation partner 2
Synonyms: C330013D05Rik, Cbfa2t2h, MTGR1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 12396
HGNC: HGNC:1536
Homologene: 3733
Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Synonyms: UF2-H3B, Ftf, D1Ertd308e, LRH-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 26424
HGNC: HGNC:7984
Homologene: 20827
Fbxl17
Name: F-box and leucine-rich repeat protein 17
Synonyms: 6330576B01Rik, Fbxo13, Fbx13, C130023C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 50758
Homologene: 79859
Iars
Name: isoleucine-tRNA synthetase
Synonyms: E430001P04Rik, 2510016L12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105148
HGNC: HGNC:5330
Homologene: 5325
Cog5
Name: component of oligomeric golgi complex 5
Synonyms: GOLTC1, 5430405C01Rik, GTC90
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238123
VEGA: 12
Homologene: 42221
Mki67
Name: antigen identified by monoclonal antibody Ki 67
Synonyms: Ki-67, Ki67, D630048A14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 17345
HGNC: HGNC:7107
Homologene: 1814
Tigar
Name: Trp53 induced glycolysis regulatory phosphatase
Synonyms: 9630033F20Rik, Tigar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 319801
HGNC: HGNC:1185
Homologene: 32473
Ap3d1
Name: adaptor-related protein complex 3, delta 1 subunit
Synonyms: mBLVR1, Bolvr
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 11776
VEGA: 10
HGNC: HGNC:568
Homologene: 2926
Drg2
Name: developmentally regulated GTP binding protein 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13495
HGNC: HGNC:3030
Homologene: 1061
Atp13a5
Name: ATPase type 13A5
Synonyms: C630015F21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 268878
Homologene: 77451
Hhip
Name: Hedgehog-interacting protein
Synonyms: Hip, Hhip1, Hip1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 15245
Homologene: 32469
AU040320
Name: expressed sequence AU040320
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100317
Homologene: 11764
Akap2
Name: A kinase (PRKA) anchor protein 2
Synonyms: B230340M18Rik, AKAP-KL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Hspa12b
Name: heat shock protein 12B
Synonyms: 2700081N06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 72630
Homologene: 41749
Tgm5
Name: transglutaminase 5
Synonyms: TGx, 2310007C07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74176
Homologene: 20899
Lcn5
Name: lipocalin 5
Synonyms: mE-RABP, Erabp, MEP10
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 13863
Homologene: 7305
Gm10691
Name: predicted gene 10691
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Dnah9
Name: dynein, axonemal, heavy chain 9
Synonyms: D11Ertd686e, Dnahc9
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 237806
HGNC: HGNC:2953
Homologene: 20357
Fer1l4
Name: fer-1-like 4 (C. elegans)
Synonyms: 9130402C12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74562
Homologene: 19075
Arhgap5
Name: Rho GTPase activating protein 5
Synonyms: p190B, p190-B
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 11855
VEGA: 12
HGNC: HGNC:675
Homologene: 907
Mmp3
Name: matrix metallopeptidase 3
Synonyms: Str1, SLN1, SLN-1, stromelysin-1, STR-1, stromelysin 1, progelatinase, Stmy1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 17392
VEGA: 9
HGNC: HGNC:7173
Homologene: 20545
Olfr1477
Name: olfactory receptor 1477
Synonyms: MOR202-10, GA_x6K02T2RE5P-3834960-3835907
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 258691
Homologene: 110492
Srgap1
Name: SLIT-ROBO Rho GTPase activating protein 1
Synonyms: Arhgap13, 4930572H05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 117600
Homologene: 56898
Myt1l
Name: myelin transcription factor 1-like
Synonyms: 2900093J19Rik, Png-1, 2900046C06Rik, C630034G21Rik, Pmng1, Nztf1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 17933
VEGA: 12
HGNC: HGNC:7623
Homologene: 7435
Col9a1
Name: collagen, type IX, alpha 1
Synonyms: Col9a-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 12839
HGNC: HGNC:2217
Homologene: 1393
Sirpb1c
Name: signal-regulatory protein beta 1C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 100038947
Homologene: 82993
Prpf40b
Name: pre-mRNA processing factor 40B
Synonyms: 2610317D23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 54614
Homologene: 81828
Samd9l
Name: sterile alpha motif domain containing 9-like
Synonyms: ESTM25
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 209086
HGNC: HGNC:1349
Homologene: 7707
Gp6
Name: glycoprotein 6 (platelet)
Synonyms: 9830166G18Rik, Gpvi
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 243816
Homologene: 9488
Neil1
Name: nei endonuclease VIII-like 1 (E. coli)
Synonyms: 2810450N13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72774
Homologene: 11616
Zfp426
Name: zinc finger protein 426
Synonyms: 2900057C04Rik, KRAB1, Zfp68-rs1, Zfo61
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235028
Homologene: 23435
Cenpj
Name: centromere protein J
Synonyms: Sas4, 4932437H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 219103
Homologene: 10204
Adgrg6
Name: adhesion G protein-coupled receptor G6
Synonyms: 1190004A11Rik, LOC215798, DREG, Gpr126
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 215798
Homologene: 10724
Olfr561
Name: olfactory receptor 561
Synonyms: GA_x6K02T2PBJ9-5491151-5492095, MOR14-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 259096
Homologene: 133029
Daxx
Name: Fas death domain-associated protein
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13163
HGNC: HGNC:2681
Homologene: 1033
Pde8b
Name: phosphodiesterase 8B
Synonyms: C030047E14Rik, B230331L10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 218461
HGNC: HGNC:8794
Homologene: 2758
9430097D07Rik
Name: RIKEN cDNA 9430097D07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 319245
VEGA: 2
Ttll11
Name: tubulin tyrosine ligase-like family, member 11
Synonyms: 4933424A20Rik, D2Ertd624e, 4932702F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 74410
Homologene: 77534
Tmprss11b
Name: transmembrane protease, serine 11B
Synonyms: Tmprss11bnl, 9930019B18Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 319875
Homologene: 64599
Ccdc62
Name: coiled-coil domain containing 62
Synonyms: repro29, G1-485-3, LOC208908
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 208908
Homologene: 82466
Olfr857
Name: olfactory receptor 857
Synonyms: GA_x6K02T2PVTD-13452606-13453535, MOR146-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 257963
Homologene: 134093
Olfr380
Name: olfactory receptor 380
Synonyms: MOR135-1, GA_x6K02T2P1NL-3613021-3612086
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 259027
Homologene: 74109
Spertl
Name: spermatid associated like
Synonyms: 4921530L21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 66732
VEGA: 14
Homologene: 41645
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • T to A, chromosome 1 at 24,185,247 bp
  • T to C, chromosome 1 at 136,845,692 bp
  • T to C, chromosome 2 at 12,182,721 bp
  • T to C, chromosome 2 at 25,660,693 bp
  • T to C, chromosome 2 at 32,574,406 bp
  • T to C, chromosome 2 at 35,902,676 bp
  • T to A, chromosome 2 at 121,053,574 bp
  • G to T, chromosome 2 at 131,144,799 bp
  • T to A, chromosome 2 at 154,531,349 bp
  • T to C, chromosome 2 at 156,024,010 bp
  • T to C, chromosome 3 at 15,833,145 bp
  • A to G, chromosome 3 at 95,308,076 bp
  • C to A, chromosome 4 at 57,855,628 bp
  • G to A, chromosome 4 at 65,613,254 bp
  • A to T, chromosome 4 at 126,837,362 bp
  • A to G, chromosome 5 at 86,660,467 bp
  • G to A, chromosome 5 at 123,954,748 bp
  • T to C, chromosome 6 at 3,375,107 bp
  • A to G, chromosome 6 at 127,091,182 bp
  • A to T, chromosome 7 at 4,370,142 bp
  • A to T, chromosome 7 at 102,775,079 bp
  • G to A, chromosome 7 at 135,704,406 bp
  • T to C, chromosome 8 at 79,997,492 bp
  • G to A, chromosome 9 at 7,451,768 bp
  • G to T, chromosome 9 at 19,713,447 bp
  • T to C, chromosome 9 at 20,471,245 bp
  • T to C, chromosome 9 at 57,146,896 bp
  • C to T, chromosome 10 at 14,426,898 bp
  • G to T, chromosome 10 at 80,727,978 bp
  • A to T, chromosome 10 at 121,855,536 bp
  • T to A, chromosome 11 at 60,461,581 bp
  • A to G, chromosome 11 at 66,130,562 bp
  • A to T, chromosome 11 at 73,454,080 bp
  • A to G, chromosome 12 at 29,811,501 bp
  • T to C, chromosome 12 at 31,837,181 bp
  • T to C, chromosome 12 at 52,516,308 bp
  • G to A, chromosome 13 at 49,703,233 bp
  • G to T, chromosome 13 at 95,046,454 bp
  • T to C, chromosome 14 at 56,549,496 bp
  • T to A, chromosome 14 at 95,882,365 bp
  • T to C, chromosome 15 at 99,305,199 bp
  • A to G, chromosome 16 at 29,348,755 bp
  • T to A, chromosome 17 at 33,913,893 bp
  • G to A, chromosome 17 at 63,356,851 bp
  • A to G, chromosome 19 at 13,503,077 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0356 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038562-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.