Strain Name:
C57BL/6J-MtgxR0547Btlr/Mmmh
Stock Number:
038739-MU
Citation ID:
RRID:MMRRC_038739-MU
Other Names:
R0547 (G1), C57BL/6J-MtgxR0547Btlr
Major Collection:

Gene Information

Trim32
Name: tripartite motif-containing 32
Synonyms: Zfp117, 1810045E12Rik, 3f3, BBS11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 69807
Homologene: 36327
Ntrk2
Name: neurotrophic tyrosine kinase, receptor, type 2
Synonyms: Tkrb, C030027L06Rik, trkB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 18212
VEGA: 13
HGNC: HGNC:8032
Homologene: 4504
Cdon
Name: cell adhesion molecule-related/down-regulated by oncogenes
Synonyms: CDO, CAM-related/down-regulated by oncogenes
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 57810
Homologene: 22996
Ntrk1
Name: neurotrophic tyrosine kinase, receptor, type 1
Synonyms: Tkr, TrkA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 18211
HGNC: HGNC:8031
Homologene: 1898
Sipa1l1
Name: signal-induced proliferation-associated 1 like 1
Synonyms: 4931426N11Rik, Spar
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217692
VEGA: 12
Homologene: 9189
Gpr26
Name: G protein-coupled receptor 26
Synonyms: 9630036A11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 233919
HGNC: HGNC:4481
Homologene: 17764
Eif4g2
Name: eukaryotic translation initiation factor 4, gamma 2
Synonyms: E130105L11Rik, Nat1, DAP-5, Natm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 13690
HGNC: HGNC:3297
Homologene: 37477
Flnb
Name: filamin, beta
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 286940
HGNC: HGNC:3755
Homologene: 37480
Atr
Name: ataxia telangiectasia and Rad3 related
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 245000
HGNC: HGNC:882
Homologene: 96916
Senp7
Name: SUMO1/sentrin specific peptidase 7
Synonyms: 2900036C23Rik, 6030449K19Rik, 2410152H17Rik, 2810413I22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 66315
Homologene: 10778
Mms19
Name: MMS19 cytosolic iron-sulfur assembly component
Synonyms: Mms19l, 2610042O15Rik, C86341, Mms19
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 72199
Homologene: 41480
Copa
Name: coatomer protein complex subunit alpha
Synonyms: xenin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 12847
HGNC: HGNC:2230
Homologene: 3218
Inppl1
Name: inositol polyphosphate phosphatase-like 1
Synonyms: SHIP2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 16332
HGNC: HGNC:6080
Homologene: 1204
Cep350
Name: centrosomal protein 350
Synonyms: 4933409L06Rik, 6430546F08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74081
Homologene: 8879
Jam3
Name: junction adhesion molecule 3
Synonyms: Jcam3, JAM-3, JAM-C, 1110002N23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 83964
Homologene: 11338
Olfr734
Name: olfactory receptor 734
Synonyms: GA_x6K02T2PMLR-6013665-6012724, MOR242-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 258658
Homologene: 51759
Adamtsl1
Name: ADAMTS-like 1
Synonyms: 6720426B09Rik, 5930437A14Rik, punctin-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 77739
Homologene: 64642
Gfral
Name: GDNF family receptor alpha like
Synonyms: GRAL
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 404194
Homologene: 45748
Slain1
Name: SLAIN motif family, member 1
Synonyms: 9630044O09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 105439
Homologene: 16943
Bicra
Name: BRD4 interacting chromatin remodeling complex associated protein
Synonyms: Gltscr1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243842
HGNC: HGNC:4332
Homologene: 9250
Ythdc2
Name: YTH domain containing 2
Synonyms: 3010002F02Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 240255
Homologene: 11265
Pkd1l1
Name: polycystic kidney disease 1 like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 171395
Homologene: 51376
Cyp4f18
Name: cytochrome P450, family 4, subfamily f, polypeptide 18
Synonyms: 1810054N16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 72054
HGNC: HGNC:2645
Homologene: 128623
Ttn
Name: titin
Synonyms: shru, connectin, mdm, 2310057K23Rik, D330041I19Rik, 1100001C23Rik, D830007G01Rik, 2310036G12Rik, L56, 2310074I15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 22138
Homologene: 130650
Pclo
Name: piccolo (presynaptic cytomatrix protein)
Synonyms: Acz, Pico
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 26875
Homologene: 69111
Prkag3
Name: protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Synonyms: AMPKg3L, AMPKg3, AMPKg3S
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 241113
HGNC: HGNC:9387
Homologene: 23006
Dnah6
Name: dynein, axonemal, heavy chain 6
Synonyms: A730004I20Rik, Dnahc6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 330355
HGNC: HGNC:2951
Homologene: 15221
Olfr651
Name: olfactory receptor 651
Synonyms: MOR31-11, GA_x6K02T2PBJ9-7179540-7180481
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 258809
HGNC: null
Homologene: 64922
Tnn
Name: tenascin N
Synonyms: Tnw, tenascin-W
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 329278
Homologene: 18634
Il23r
Name: interleukin 23 receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 209590
Homologene: 16930
Aox2
Name: aldehyde oxidase 2
Synonyms: Aox3l1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 213043
HGNC: null
Homologene: 84622
Gm884
Name: predicted gene 884
Synonyms: LOC380730
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 380730
Homologene: 134511
Haus5
Name: HAUS augmin-like complex, subunit 5
Synonyms: 2310022K01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 71909
Homologene: 18969
Tshz3
Name: teashirt zinc finger family member 3
Synonyms: Zfp537, Tsh3, teashirt3, A630038G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 243931
Homologene: 10835
Odf3
Name: outer dense fiber of sperm tails 3
Synonyms: SHIPPO1, 1700011O04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 69287
Homologene: 12306
Dgkb
Name: diacylglycerol kinase, beta
Synonyms: DGK-beta, C630029D13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 217480
VEGA: 12
HGNC: HGNC:2850
Homologene: 37875
Pde8a
Name: phosphodiesterase 8A
Synonyms: Pde8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 18584
HGNC: HGNC:8793
Homologene: 1957
Greb1
Name: gene regulated by estrogen in breast cancer protein
Synonyms: 5730583K22Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 268527
Homologene: 8780
Rxfp1
Name: relaxin/insulin-like family peptide receptor 1
Synonyms: Lgr7, LOC381489
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 381489
Homologene: 11007
Mylk
Name: myosin, light polypeptide kinase
Synonyms: MLCK108, A930019C19Rik, Mlck, nmMlck, telokin, MLCK210, 9530072E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 107589
HGNC: HGNC:7590
Homologene: 14202
Mup5
Name: major urinary protein 5
Synonyms: Mup V
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 17844
HGNC: null
Homologene: 74304
CAAA01221083.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
Pgbd1
Name: piggyBac transposable element derived 1
Synonyms: 4921509E05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 319207
Homologene: 130030
AC073590.1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
Padi4
Name: peptidyl arginine deiminase, type IV
Synonyms: Pdi4, PAD type IV, Pad4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 18602
Homologene: 7883
Zfp827
Name: zinc finger protein 827
Synonyms: D630040G17Rik, 2810449M09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 622675
Homologene: 45622
Serpina1e
Name: serine (or cysteine) peptidase inhibitor, clade A, member 1E
Synonyms: Spi1-5, PI5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
Alteration at locus: Chemically Induced
NCBI: 20704
HGNC: HGNC:8941
Homologene: 20103
Car5b
Name: carbonic anhydrase 5b, mitochondrial
Synonyms: CAVB, 7330410H16Rik, D730005F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 56078
HGNC: HGNC:1378
Homologene: 21413
Nuak2
Name: NUAK family, SNF1-like kinase, 2
Synonyms: 1200013B22Rik, Snark
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 74137
Homologene: 12539
Etfb
Name: electron transferring flavoprotein, beta polypeptide
Synonyms: 2810441H06Rik, 0610009I16Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 110826
HGNC: HGNC:3482
Homologene: 1503
G430095P16Rik
Name: RIKEN cDNA G430095P16 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 619292
HGNC: null
Homologene: null
Slc37a2
Name: solute carrier family 37 (glycerol-3-phosphate transporter), member 2
Synonyms: G3PP, cI-2, ci2, Slc37a1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 56857
Homologene: 41357
Thg1l
Name: tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
Synonyms: 1700121M19Rik, 5730409G07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 66628
Homologene: 5959
A530084C06Rik
Name: RIKEN cDNA A530084C06 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: null
VEGA: null
HGNC: null
Homologene: null
Ankrd55
Name: ankyrin repeat domain 55
Synonyms: C030011J08Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 77318
VEGA: 13
Homologene: 12674
2310057N15Rik
Name: RIKEN cDNA 2310057N15 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 69696
Homologene: 114409
Rsph9
Name: radial spoke head 9 homolog (Chlamydomonas)
Synonyms: 1700027N10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 75564
Homologene: 12606
Cabyr
Name: calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
Synonyms: CBP86, 4933421A18Rik, 1700016C01Rik, FSP-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
Alteration at locus: Chemically Induced
NCBI: 71132
Homologene: 49299
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 58,310,042 bp
  • C to T, chromosome 1 at 74,744,720 bp
  • C to A, chromosome 1 at 132,332,203 bp
  • C to T, chromosome 1 at 155,901,435 bp
  • A to G, chromosome 1 at 160,116,337 bp
  • T to C, chromosome 1 at 172,121,687 bp
  • C to G, chromosome 2 at 76,854,430 bp
  • A to T, chromosome 3 at 79,705,569 bp
  • A to T, chromosome 3 at 87,788,800 bp
  • A to G, chromosome 4 at 61,833,000 bp
  • G to A, chromosome 4 at 65,613,254 bp
  • A to G, chromosome 4 at 86,356,355 bp
  • GCTGCGTACCTCCAC to GC, chromosome 4 at 140,748,449 bp
  • T to A, chromosome 5 at 14,792,072 bp
  • A to T, chromosome 6 at 67,423,701 bp
  • A to T, chromosome 6 at 67,486,251 bp
  • T to C, chromosome 6 at 73,044,774 bp
  • G to A, chromosome 7 at 15,972,248 bp
  • A to T, chromosome 7 at 30,659,083 bp
  • A to G, chromosome 7 at 36,771,417 bp
  • C to T, chromosome 7 at 43,454,578 bp
  • G to T, chromosome 7 at 81,324,130 bp
  • A to T, chromosome 7 at 101,831,003 bp
  • G to A, chromosome 7 at 104,553,356 bp
  • T to C, chromosome 7 at 111,078,293 bp
  • T to C, chromosome 7 at 131,984,297 bp
  • A to G, chromosome 7 at 140,848,815 bp
  • CGTG to CGTGTG, chromosome 7 at 141,699,185 bp
  • T to C, chromosome 8 at 71,996,010 bp
  • A to G, chromosome 8 at 79,060,310 bp
  • G to A, chromosome 8 at 84,726,642 bp
  • A to G, chromosome 9 at 27,098,888 bp
  • A to T, chromosome 9 at 35,457,498 bp
  • A to T, chromosome 9 at 37,233,122 bp
  • A to T, chromosome 9 at 76,208,642 bp
  • A to T, chromosome 9 at 95,899,165 bp
  • A to G, chromosome 11 at 8,836,448 bp
  • C to T, chromosome 11 at 45,954,191 bp
  • T to C, chromosome 11 at 103,620,164 bp
  • T to A, chromosome 12 at 16,723,411 bp
  • T to A, chromosome 12 at 38,604,158 bp
  • T to A, chromosome 12 at 82,437,736 bp
  • G to T, chromosome 12 at 103,949,191 bp
  • T to C, chromosome 12 at 114,406,601 bp
  • A to G, chromosome 13 at 21,423,518 bp
  • A to G, chromosome 13 at 31,558,830 bp
  • G to A, chromosome 13 at 58,874,370 bp
  • T to C, chromosome 13 at 112,368,223 bp
  • T to A, chromosome 14 at 7,912,943 bp
  • A to T, chromosome 14 at 50,320,118 bp
  • T to C, chromosome 14 at 103,695,275 bp
  • G to C, chromosome 16 at 34,879,475 bp
  • A to G, chromosome 16 at 56,175,826 bp
  • A to G, chromosome 16 at 88,773,610 bp
  • A to T, chromosome 17 at 46,144,124 bp
  • T to A, chromosome 18 at 12,751,016 bp
  • T to C, chromosome 18 at 44,840,264 bp
  • A to T, chromosome 19 at 41,963,418 bp
  • G to A, chromosome X at 163,979,301 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0547 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038739-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.