Strain Name:
C57BL/6J-MtgxR0661Btlr/Mmmh
Stock Number:
038846-MU
Citation ID:
RRID:MMRRC_038846-MU
Other Names:
R0661 (G1), C57BL/6J-MtgxR0661Btlr
Major Collection:

Gene Information

Col1a1
Name: collagen, type I, alpha 1
Synonyms: Mov-13, Cola1, Col1a-1, Cola-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 12842
HGNC: HGNC:2197
Homologene: 73874
Drd1
Name: dopamine receptor D1
Synonyms: C030036C15Rik, D1 receptor, Gpcr15, Drd-1, Drd1a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 13488
VEGA: 13
HGNC: HGNC:3020
Homologene: 30992
Anks3
Name: ankyrin repeat and sterile alpha motif domain containing 3
Synonyms: 2700067D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 72615
VEGA: 16
Homologene: 12475
Tut7
Name: terminal uridylyl transferase 7
Synonyms: Zcchc6, Tent3b, 6030448M23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 214290
VEGA: 13
Homologene: 51941
Usf1
Name: upstream transcription factor 1
Synonyms: bHLHb11, upstream stimulatory factor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
Alteration at locus: Chemically Induced
NCBI: 22278
Homologene: 31426
Ranbp2
Name: RAN binding protein 2
Synonyms: A430087B05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
Alteration at locus: Chemically Induced
NCBI: 19386
VEGA: 10
Homologene: 87808
Asxl1
Name: additional sex combs like 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 228790
Homologene: 9098
Prdm15
Name: PR domain containing 15
Synonyms: E130018M06Rik, Zfp298
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 114604
Homologene: 56941
Slf1
Name: SMC5-SMC6 complex localization factor 1
Synonyms: 2700017A04Rik, Ankrd32, Brctd1, C730024G01Rik, Brctx
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 105377
Homologene: 13000
Clca2
Name: chloride channel accessory 2
Synonyms: Clca5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 229933
HGNC: HGNC:2016
Homologene: 4765
Lrrk2
Name: leucine-rich repeat kinase 2
Synonyms: cI-46, 4921513O20Rik, D630001M17Rik, 9330188B09Rik, LOC381026
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 66725
Homologene: 18982
Zfand3
Name: zinc finger, AN1-type domain 3
Synonyms: TEG-27, Tex27
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21769
VEGA: 17
Homologene: 11077
Zfp740
Name: zinc finger protein 740
Synonyms: 1110034O07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
Alteration at locus: Chemically Induced
NCBI: 68744
Homologene: 129530
Heyl
Name: hairy/enhancer-of-split related with YRPW motif-like
Synonyms: bHLHb33, Hrt3, Hey3, Hesr3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 56198
HGNC: HGNC:4882
Homologene: 8494
Tcp1
Name: t-complex protein 1
Synonyms: Cct1, Tcp-1, Ccta, p63, c-cpn, TRic, Tp63, CCT
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 21454
Homologene: 5656
Msh3
Name: mutS homolog 3
Synonyms: D13Em1, Rep-3, Rep3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
Alteration at locus: Chemically Induced
NCBI: 17686
HGNC: HGNC:7326
Homologene: 1829
Yme1l1
Name: YME1-like 1 (S. cerevisiae)
Synonyms: ATP-dependent metalloprotease FtsH1, Ftsh
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 27377
Homologene: 31996
Brip1
Name: BRCA1 interacting protein C-terminal helicase 1
Synonyms: 3110009N10Rik, 8030460J03Rik, BACH1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 237911
Homologene: 32766
Invs
Name: inversin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
Alteration at locus: Chemically Induced
NCBI: 16348
Homologene: 7786
Ar
Name: androgen receptor
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 11835
HGNC: HGNC:644
Homologene: 28
Dhx57
Name: DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 106794
VEGA: 17
Homologene: 56267
Fsip2
Name: fibrous sheath-interacting protein 2
Synonyms: OTTMUSG00000013335
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 241516
Homologene: 110349
Cpne2
Name: copine II
Synonyms: 3322401K10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234577
HGNC: HGNC:2315
Homologene: 27392
Slc26a6
Name: solute carrier family 26, member 6
Synonyms: Pat1, CFEX, B930010B04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 171429
Homologene: 99903
BC051142
Name: cDNA sequence BC051142
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
Alteration at locus: Chemically Induced
NCBI: 407788
Homologene: 128168
Olfr1458
Name: olfactory receptor 1458
Synonyms: MOR202-24, EG667271, GA_x6K02T2RE5P-3430689-3429787
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 667271
Cd109
Name: CD109 antigen
Synonyms: Gov platelet alloantigens, 9930012E15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
Alteration at locus: Chemically Induced
NCBI: 235505
Homologene: 25183
Vmn2r75
Name: vomeronasal 2, receptor 75
Synonyms: EG546981
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 546981
Homologene: 115466
Olfr743
Name: olfactory receptor 743
Synonyms: MOR106-14, GA_x6K02T2PMLR-6243196-6244132, Olfr743-ps1, Olfr265, Olfr264, GA_x6K02T2N6FY-2320-2039, GA_x6K02T2N6FY-3870-3385, MOR106-8P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
Alteration at locus: Chemically Induced
NCBI: 219019
Homologene: 74163
Grin2a
Name: glutamate receptor, ionotropic, NMDA2A (epsilon 1)
Synonyms: GluN2A, NMDAR2A, GluRepsilon1, NR2A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
Alteration at locus: Chemically Induced
NCBI: 14811
HGNC: HGNC:4585
Homologene: 645
Pcdh18
Name: protocadherin 18
Synonyms: PCDH68L
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 73173
Homologene: 10389
Dcaf17
Name: DDB1 and CUL4 associated factor 17
Synonyms: A030004A10Rik, A930009G19Rik, 4833418A01Rik, 2810055O12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 75763
Homologene: 65979
Sec11a
Name: SEC11 homolog A, signal peptidase complex subunit
Synonyms: Sec11l1, 1810012E07Rik, sid2895, 18kDa, Spc18
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 56529
Homologene: 55536
Tm6sf1
Name: transmembrane 6 superfamily member 1
Synonyms: C630016D09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
Alteration at locus: Chemically Induced
NCBI: 107769
Homologene: 11305
Inpp4b
Name: inositol polyphosphate-4-phosphatase, type II
Synonyms: E130107I17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 234515
HGNC: HGNC:6075
Homologene: 20832
Shroom1
Name: shroom family member 1
Synonyms: Apx, 1300007L22Rik, Shrm1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 71774
Homologene: 12411
Agtr1b
Name: angiotensin II receptor, type 1b
Synonyms: AT1B, Angtr-1b, Agtr-1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
Alteration at locus: Chemically Induced
NCBI: 11608
HGNC: HGNC:336
Homologene: 84871
Rimbp2
Name: RIMS binding protein 2
Synonyms: A930033C01Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
Alteration at locus: Chemically Induced
NCBI: 231760
Homologene: 14672
Ufsp2
Name: UFM1-specific peptidase 2
Synonyms: 1810047C23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
Alteration at locus: Chemically Induced
NCBI: 192169
Homologene: 10151
Cdk9
Name: cyclin-dependent kinase 9 (CDC2-related kinase)
Synonyms: PITALRE
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 107951
HGNC: HGNC:1780
Homologene: 55566
C1ra
Name: complement component 1, r subcomponent A
Synonyms: mC1rA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 50909
HGNC: HGNC:1246
Homologene: 1313
Olfr1431
Name: olfactory receptor 1431
Synonyms: MOR214-5, GA_x6K02T2RE5P-2573738-2574676
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 258409
Homologene: 115495
Hoxd12
Name: homeobox D12
Synonyms: Hox-4.7, Hox-5.6
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
NCBI: 15432
HGNC: HGNC:5135
Homologene: 7369
Gm20721
Name: predicted gene, 20721
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
Alteration at locus: Chemically Induced
Spx
Name: spexin hormone
Synonyms: B230216G23Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
Alteration at locus: Chemically Induced
NCBI: 319552
Homologene: 79576
Krt27
Name: keratin 27
Synonyms: stpm, mIRSa3.1, Krt1-c29
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
Alteration at locus: Chemically Induced
NCBI: 16675
Homologene: 7805
Rela
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Synonyms: p65 NF kappaB, p65
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
Alteration at locus: Chemically Induced
NCBI: 19697
HGNC: HGNC:9955
Homologene: 32064
Rtl5
Name: retrotransposon Gag like 5
Synonyms: 6430402L03Rik, Mart5, Rgag4, Mar5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 331474
Homologene: 18846
Itm2a
Name: integral membrane protein 2A
Synonyms: Itm2, Bricd2a
Type: Gene
Species: Mus musculus (mouse)
Chromosome: X
Alteration at locus: Chemically Induced
NCBI: 16431
HGNC: HGNC:6173
Homologene: 31269
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • G to A, chromosome 1 at 171,417,499 bp
  • T to A, chromosome 2 at 23,191,042 bp
  • G to A, chromosome 2 at 32,709,820 bp
  • T to C, chromosome 2 at 71,088,435 bp
  • A to G, chromosome 2 at 74,675,892 bp
  • A to G, chromosome 2 at 82,986,169 bp
  • T to A, chromosome 2 at 153,400,724 bp
  • T to C, chromosome 2 at 174,334,208 bp
  • T to A, chromosome 3 at 20,315,999 bp
  • A to C, chromosome 3 at 49,753,318 bp
  • A to G, chromosome 3 at 145,095,110 bp
  • G to A, chromosome 4 at 48,421,861 bp
  • G to T, chromosome 4 at 123,246,031 bp
  • A to G, chromosome 5 at 128,786,710 bp
  • T to A, chromosome 6 at 124,522,377 bp
  • A to G, chromosome 6 at 142,413,839 bp
  • A to G, chromosome 7 at 80,935,039 bp
  • G to A, chromosome 7 at 81,865,345 bp
  • G to A, chromosome 7 at 86,165,658 bp
  • T to A, chromosome 8 at 45,979,233 bp
  • C to A, chromosome 8 at 81,741,462 bp
  • T to C, chromosome 8 at 94,556,039 bp
  • T to C, chromosome 9 at 78,680,170 bp
  • T to C, chromosome 9 at 108,859,113 bp
  • T to G, chromosome 10 at 58,478,733 bp
  • T to C, chromosome 11 at 53,466,937 bp
  • A to T, chromosome 11 at 86,110,363 bp
  • A to G, chromosome 11 at 94,949,389 bp
  • A to G, chromosome 11 at 99,350,013 bp
  • T to A, chromosome 13 at 54,053,038 bp
  • A to G, chromosome 13 at 59,796,934 bp
  • A to G, chromosome 13 at 77,083,596 bp
  • T to C, chromosome 13 at 92,345,096 bp
  • A to G, chromosome 14 at 50,534,095 bp
  • T to C, chromosome 15 at 91,787,016 bp
  • A to G, chromosome 15 at 102,212,659 bp
  • A to G, chromosome 16 at 4,948,334 bp
  • G to T, chromosome 16 at 9,992,472 bp
  • A to T, chromosome 16 at 97,829,682 bp
  • T to C, chromosome 17 at 12,923,313 bp
  • A to G, chromosome 17 at 30,135,398 bp
  • A to T, chromosome 17 at 34,459,913 bp
  • C to T, chromosome 17 at 80,268,864 bp
  • T to A, chromosome 19 at 5,639,016 bp
  • T to C, chromosome 19 at 12,209,704 bp
  • G to A, chromosome 19 at 13,103,278 bp
  • T to A, chromosome X at 98,150,565 bp
  • T to C, chromosome X at 102,070,450 bp
  • T to C, chromosome X at 107,399,091 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0661 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $) Units Notes
038846-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter1; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

3 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.