Strain Name:
C57BL/6J-MtgxR0843Btlr/Mmmh
Stock Number:
039022-MU
Citation ID:
RRID:MMRRC_039022-MU
Other Names:
R0843 (G1), C57BL/6J-MtgxR0843Btlr
Major Collection:

Gene Information

Dnmt3a
Name: DNA methyltransferase 3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13435
HGNC: HGNC:2978
Homologene: 7294
Spry2
Name: sprouty RTK signaling antagonist 2
Synonyms: sprouty2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 24064
VEGA: 14
Homologene: 4267
Efr3a
Name: EFR3 homolog A
Synonyms: A130089M23Rik, D030063F01Rik, C920006C10Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 76740
Homologene: 44222
Cyfip1
Name: cytoplasmic FMR1 interacting protein 1
Synonyms: P140SRA-1, Shyc, pl-1, l(7)1Rl, Sra-1, E030028J09Rik, l7Rl1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 20430
Homologene: 22628
Rangap1
Name: RAN GTPase activating protein 1
Synonyms: Fug1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 19387
VEGA: 15
HGNC: HGNC:9854
Homologene: 55700
Zc3h3
Name: zinc finger CCCH type containing 3
Synonyms: Smicl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 223642
VEGA: 15
Homologene: 9029
Kctd3
Name: potassium channel tetramerisation domain containing 3
Synonyms: NY-REN-45, E330032J19Rik, 4930438A20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226823
Homologene: 9395
Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
Synonyms: MAP1C, dynein heavy chain, retrograde transport, Dnec1, Loa, 9930018I23Rik, Dnchc1, Swl
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 13424
HGNC: HGNC:2961
Homologene: 1053
Slitrk6
Name: SLIT and NTRK-like family, member 6
Synonyms: 4832410J21Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 239250
VEGA: 14
Homologene: 12986
Arrdc3
Name: arrestin domain containing 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 105171
Homologene: 69318
Ppm1g
Name: protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
Synonyms: Fin13
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 14208
HGNC: HGNC:9278
Homologene: 31106
Xpo5
Name: exportin 5
Synonyms: 2410004H11Rik, 2700038C24Rik, Exp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 72322
VEGA: 17
Homologene: 69316
Iqgap3
Name: IQ motif containing GTPase activating protein 3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 404710
Homologene: 26400
Zfp277
Name: zinc finger protein 277
Synonyms: NIRF4, 2410017E24Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 246196
VEGA: 12
Homologene: 11087
Dnah8
Name: dynein, axonemal, heavy chain 8
Synonyms: Hst6.7b, P1-Loop, Dnahc8
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 13417
VEGA: 17
HGNC: HGNC:2952
Homologene: 1049
Rad54b
Name: RAD54 homolog B (S. cerevisiae)
Synonyms: E130016E03Rik, E130016E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 623474
Homologene: 8240
Hspa1b
Name: heat shock protein 1B
Synonyms: hsp68, Hsp70.1, Hsp70-1, HSP70B1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 15511
HGNC: HGNC:5233
Homologene: 133785
Hsh2d
Name: hematopoietic SH2 domain containing
Synonyms: ALX, Hsh2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209488
Homologene: 13142
Pcsk5
Name: proprotein convertase subtilisin/kexin type 5
Synonyms: PC6, SPC6, PC5A, PC5/6A, b2b585Clo, b2b1549Clo
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 18552
VEGA: 19
HGNC: HGNC:8747
Homologene: 21244
Cacna1d
Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Synonyms: D-LTCC, Cchl1a, Cchl1a2, Cacnl1a2, 8430418G19Rik, Cav1.3alpha1, C79217
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 14
NCBI: 12289
VEGA: 14
HGNC: HGNC:1391
Homologene: 578
Vmn2r116
Name: vomeronasal 2, receptor 116
Synonyms: EG619697, V2Rp5
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 619697
Homologene: 86604
Myo7b
Name: myosin VIIB
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 17922
HGNC: HGNC:7607
Homologene: 81947
Ifi207
Name: interferon activated gene 207
Synonyms: AI607873, Pyhin-A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 226691
HGNC: HGNC:5395
Homologene: 115929
Stx2
Name: syntaxin 2
Synonyms: Epim, G1-536-1, repro34, Syn-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 13852
HGNC: HGNC:3403
Homologene: 37559
Rhbdf1
Name: rhomboid 5 homolog 1
Synonyms: Dist1, Egfr-rs, Dist
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 13650
Homologene: 32085
Olfr591
Name: olfactory receptor 591
Synonyms: GA_x6K02T2PBJ9-5889409-5888465, MOR24-1P
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258139
Homologene: 79429
Adrb2
Name: adrenergic receptor, beta 2
Synonyms: beta 2-AR, Badm, Adrb-2, beta 2-adrenoceptor, Gpcr7
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 11555
VEGA: 18
HGNC: HGNC:286
Homologene: 30948
Plxnb1
Name: plexin B1
Synonyms: 2900002G15Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 235611
HGNC: HGNC:9103
Homologene: 130508
Gabrr1
Name: gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
Synonyms: GABA-C
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 14408
HGNC: HGNC:4090
Homologene: 20470
Tll2
Name: tolloid-like 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 24087
VEGA: 19
Homologene: 56545
Scaf11
Name: SR-related CTD-associated factor 11
Synonyms: 1110061H03Rik, SRRP129, CASP11, SIP1, 2610510E10Rik, Sfrs2ip, Srsf2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 72193
VEGA: 15
Homologene: 37957
Ptpru
Name: protein tyrosine phosphatase, receptor type, U
Synonyms: Ptprl, RPTPlambda
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 19273
HGNC: HGNC:9683
Homologene: 4168
Tent5b
Name: terminal nucleotidyltransferase 5B
Synonyms: 4732473B16Rik, Fam46b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 100342
Homologene: 24928
Pyroxd2
Name: pyridine nucleotide-disulphide oxidoreductase domain 2
Synonyms: 3830409H07Rik, 4833409A17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 74580
VEGA: 19
Homologene: 13097
Olfr893
Name: olfactory receptor 893
Synonyms: GA_x6K02T2PVTD-31889215-31890153, MOR170-11
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 258333
Homologene: 133626
Iyd
Name: iodotyrosine deiodinase
Synonyms: 0610009A07Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 70337
Homologene: 12352
Cenpn
Name: centromere protein N
Synonyms: 2610510J17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 72155
Homologene: 12450
Olfr1256
Name: olfactory receptor 1256
Synonyms: GA_x6K02T2Q125-51276848-51275928, MOR231-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 258985
Homologene: 128157
Ttyh3
Name: tweety family member 3
Synonyms: 2900029G13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 78339
Homologene: 18431
Fgf11
Name: fibroblast growth factor 11
Synonyms: Fhf3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14166
HGNC: HGNC:3667
Homologene: 3035
Polr2h
Name: polymerase (RNA) II (DNA directed) polypeptide H
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 245841
HGNC: HGNC:9195
Homologene: 4540
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to T, chromosome 1 at 173,727,577 bp
  • A to T, chromosome 1 at 188,996,973 bp
  • C to T, chromosome 2 at 89,835,616 bp
  • A to G, chromosome 3 at 88,108,431 bp
  • T to C, chromosome 4 at 11,609,471 bp
  • T to A, chromosome 4 at 33,161,717 bp
  • T to A, chromosome 4 at 131,797,948 bp
  • T to C, chromosome 4 at 133,486,531 bp
  • T to C, chromosome 5 at 31,207,551 bp
  • C to T, chromosome 5 at 128,999,548 bp
  • C to A, chromosome 5 at 140,626,446 bp
  • A to T, chromosome 7 at 55,922,820 bp
  • T to A, chromosome 7 at 103,173,119 bp
  • G to A, chromosome 8 at 72,200,460 bp
  • T to C, chromosome 8 at 116,933,306 bp
  • T to A, chromosome 9 at 38,209,283 bp
  • T to C, chromosome 9 at 109,113,701 bp
  • T to C, chromosome 10 at 3,545,663 bp
  • G to A, chromosome 11 at 32,215,053 bp
  • T to G, chromosome 11 at 69,798,776 bp
  • T to C, chromosome 12 at 3,872,886 bp
  • A to C, chromosome 12 at 40,320,600 bp
  • C to T, chromosome 12 at 110,665,213 bp
  • T to C, chromosome 13 at 80,890,803 bp
  • T to C, chromosome 14 at 30,124,871 bp
  • A to G, chromosome 14 at 105,893,090 bp
  • G to T, chromosome 14 at 110,750,098 bp
  • T to A, chromosome 15 at 65,837,423 bp
  • A to G, chromosome 15 at 75,837,479 bp
  • A to T, chromosome 15 at 81,710,502 bp
  • T to C, chromosome 15 at 96,431,825 bp
  • T to A, chromosome 16 at 20,718,899 bp
  • T to C, chromosome 17 at 23,400,960 bp
  • T to C, chromosome 17 at 30,813,095 bp
  • T to A, chromosome 17 at 34,957,548 bp
  • T to C, chromosome 17 at 46,222,650 bp
  • A to G, chromosome 18 at 31,974,084 bp
  • T to C, chromosome 18 at 62,179,071 bp
  • T to A, chromosome 19 at 17,654,818 bp
  • T to A, chromosome 19 at 41,128,463 bp
  • T to C, chromosome 19 at 42,747,547 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R0843 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039022-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.