Strain Name:
C57BL/6J-MtgxR1103Btlr/Mmmh
Stock Number:
039176-MU
Citation ID:
RRID:MMRRC_039176-MU
Other Names:
R1103 (G1), C57BL/6J-MtgxR1103Btlr
Major Collection:

Gene Information

Ltbp3
Name: latent transforming growth factor beta binding protein 3
Synonyms: Ltbp2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 16998
VEGA: 19
HGNC: HGNC:6716
Homologene: 7405
Pnmt
Name: phenylethanolamine-N-methyltransferase
Synonyms: Pent
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 18948
HGNC: HGNC:9160
Homologene: 55673
Map1b
Name: microtubule-associated protein 1B
Synonyms: MAP5, Mtap-5, Mtap5, LC1, Mtap1b
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 17755
VEGA: 13
HGNC: HGNC:6836
Homologene: 38111
Map3k4
Name: mitogen-activated protein kinase kinase kinase 4
Synonyms: MTK1, MAPKKK4, D17Rp17, RP17, D17Rp17e, Mekk4, T-associated sex reversal, Tas
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 26407
VEGA: 17
HGNC: HGNC:6856
Homologene: 31346
Luzp1
Name: leucine zipper protein 1
Synonyms: Luzp, 2700072H04Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 269593
Homologene: 11545
Erbin
Name: Erbb2 interacting protein
Synonyms: 1700028E05Rik, Erbin, Erbb2ip
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 59079
Homologene: 41282
Myo18a
Name: myosin XVIIIA
Synonyms: MyoPDZ
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 360013
Homologene: 7977
Mtf1
Name: metal response element binding transcription factor 1
Synonyms: MTF-1, metal response element-binding transcription factor 1, metalloregulatory transcription factor, Thyls
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 17764
HGNC: HGNC:7428
Homologene: 4347
Bltp1
Name: bridge-like lipid transfer protein family member 1
Synonyms: Tweek, FSA, 4932438A13Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 229227
Homologene: 52105
Trip4
Name: thyroid hormone receptor interactor 4
Synonyms: ASC-1, 4930558E03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 56404
Homologene: 9426
Tg
Name: thyroglobulin
Synonyms: Tgn
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 21819
Homologene: 2430
Dnttip2
Name: deoxynucleotidyltransferase, terminal, interacting protein 2
Synonyms: 4930588M11Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 99480
Homologene: 124162
Aftph
Name: aftiphilin
Synonyms: 9130023F12Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 216549
Homologene: 9764
Supt6
Name: SPT6, histone chaperone and transcription elongation factor
Synonyms: SPT6, 5131400N11Rik, Supt6h
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 20926
Homologene: 40661
Upf2
Name: UPF2 regulator of nonsense transcripts homolog (yeast)
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 326622
Homologene: 6101
Crebbp
Name: CREB binding protein
Synonyms: CBP, KAT3A
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 12914
HGNC: HGNC:2348
Homologene: 68393
Lrfn4
Name: leucine rich repeat and fibronectin type III domain containing 4
Synonyms: SALM3
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 19
NCBI: 225875
Homologene: 36415
Lama1
Name: laminin, alpha 1
Synonyms: Lama
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 17
NCBI: 16772
VEGA: 17
HGNC: HGNC:6481
Homologene: 21146
Ap2a1
Name: adaptor-related protein complex 2, alpha 1 subunit
Synonyms: Adtaa
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 11771
HGNC: HGNC:561
Homologene: 68997
Cul1
Name: cullin 1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 26965
HGNC: HGNC:2551
Homologene: 2663
Dtwd1
Name: DTW domain containing 1
Synonyms: 1810033A06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 69185
Homologene: 10633
Trim33
Name: tripartite motif-containing 33
Synonyms: Tif1g, 8030451N04Rik, ectodermin, Ecto
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 94093
Homologene: 9296
Cp
Name: ceruloplasmin
Synonyms: D3Ertd555e
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 12870
HGNC: HGNC:2295
Homologene: 75
Syne2
Name: spectrin repeat containing, nuclear envelope 2
Synonyms: nesprin-2, syne-2, D12Ertd777e, 6820443O06Rik, Nesp2g, Cpfl8, diminished cone electroretinogram, dice
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 319565
Homologene: 56700
Map3k5
Name: mitogen-activated protein kinase kinase kinase 5
Synonyms: ASK1, Mekk5, 7420452D20Rik, ASK
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 26408
HGNC: HGNC:6857
Homologene: 38114
Magi2
Name: membrane associated guanylate kinase, WW and PDZ domain containing 2
Synonyms: S-SCAM, Acvrinp1, Magi-2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 50791
Homologene: 8189
Cngb3
Name: cyclic nucleotide gated channel beta 3
Synonyms: CNG6, CCNC2, Cngbeta2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 4
NCBI: 30952
HGNC: HGNC:2153
Homologene: 40908
Lrrc7
Name: leucine rich repeat containing 7
Synonyms: densin
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 3
NCBI: 242274
Homologene: 10817
9530053A07Rik
Name: RIKEN cDNA 9530053A07 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 319482
Homologene: 130055
Zfp804a
Name: zinc finger protein 804A
Synonyms: C630007C17Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 241514
Homologene: 18461
Obscn
Name: obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
Synonyms: LOC380698, OTTMUSG00000005786
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 380698
Homologene: 70869
Ect2l
Name: epithelial cell transforming sequence 2 oncogene-like
Synonyms: Gm10331, C330021H03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 100045792
Homologene: 46005
Csmd3
Name: CUB and Sushi multiple domains 3
Synonyms: 4930500N14Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 15
NCBI: 239420
Homologene: 65982
Klkb1
Name: kallikrein B, plasma 1
Synonyms: Kal-3, Kal3, Klk3, PSA
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 16621
HGNC: HGNC:6371
Homologene: 68097
Myom2
Name: myomesin 2
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 17930
HGNC: HGNC:7614
Homologene: 2953
Lhpp
Name: phospholysine phosphohistidine inorganic pyrophosphate phosphatase
Synonyms: 2310007H09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 76429
Homologene: 41469
Syt16
Name: synaptotagmin XVI
Synonyms: Strep14, syt14r, Syt14l
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 12
NCBI: 238266
VEGA: 12
Homologene: 12902
Klra17
Name: killer cell lectin-like receptor, subfamily A, member 17
Synonyms: Ly49q1, Ly-49Q, Ly49Q
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 6
NCBI: 170733
Vrk2
Name: vaccinia related kinase 2
Synonyms: 2810003O05Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 69922
Homologene: 55966
Or6k4
Name: olfactory receptor family 6 subfamily K member 4
Synonyms: GA_x6K02T2P20D-21025190-21024243, MOR105-2, Olfr424
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 258716
Homologene: 103798
Or5e1
Name: olfactory receptor family 5 subfamily E member 1
Synonyms: GA_x6K02T2PBJ9-11084889-11085818, MOR195-1, Olfr513
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258718
Homologene: 64908
Nfasc
Name: neurofascin
Synonyms: D430023G06Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 269116
Homologene: 24945
Cntnap5a
Name: contactin associated protein-like 5A
Synonyms: Caspr5-1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 636808
Homologene: 43974
Flt4
Name: FMS-like tyrosine kinase 4
Synonyms: VEGFR3, VEGFR-3, Flt-4
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 14257
HGNC: HGNC:3767
Homologene: 7321
Setd4
Name: SET domain containing 4
Synonyms: ORF21
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 16
NCBI: 224440
HGNC: HGNC:1258
Homologene: 41173
Pde4c
Name: phosphodiesterase 4C, cAMP specific
Synonyms: dunce, Dpde1, E130301F19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 110385
HGNC: HGNC:8782
Homologene: 20256
Ido2
Name: indoleamine 2,3-dioxygenase 2
Synonyms: C230043N17Rik, Ido2, Indol1
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 209176
Homologene: 48830
Or5bw2
Name: olfactory receptor family 5 subfamily BW member 2
Synonyms: GA_x6K02T2QGBW-3300391-3301317, MOR222-3, Olfr1350
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 7
NCBI: 258384
Adam3
Name: a disintegrin and metallopeptidase domain 3 (cyritestin)
Synonyms: Taz83, tMDC, Cyrn1, ADAM3, Taz83
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 11497
HGNC: HGNC:209
Homologene: 69052
1700056E22Rik
Name: RIKEN cDNA 1700056E22 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 1
NCBI: 73363
Homologene: 137387
Cfap157
Name: cilia and flagella associated protein 157
Synonyms: 1700019L03Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 2
NCBI: 227736
Homologene: 53056
Rnf138
Name: ring finger protein 138
Synonyms: Trif-d, 2410015A17Rik, 2810480D20Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 18
NCBI: 56515
VEGA: 18
Homologene: 9446
Grap
Name: GRB2-related adaptor protein
Synonyms: 8430435N19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 71520
Homologene: 4822
4930524J08Rik
Name: RIKEN cDNA 4930524J08 gene
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 75129
Bud23
Name: BUD23, rRNA methyltransferase and ribosome maturation factor
Synonyms: 1110003N24Rik, Wbscr22
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 5
NCBI: 66138
Homologene: 5486
Gm17484
Name: predicted gene, 17484
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 8
NCBI: 100503003
Adpgk
Name: ADP-dependent glucokinase
Synonyms: 2610017G09Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 9
NCBI: 72141
VEGA: 9
Homologene: 41739
Sesn1
Name: sestrin 1
Synonyms: 1110002G11Rik, SEST1, PA26
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 10
NCBI: 140742
Homologene: 8697
Atpaf2
Name: ATP synthase mitochondrial F1 complex assembly factor 2
Synonyms: ATP12, ATP12p
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 11
NCBI: 246782
Homologene: 34602
Gpr150
Name: G protein-coupled receptor 150
Synonyms: PGR11, C030001A19Rik
Type: Gene
Species: Mus musculus (mouse)
Chromosome: 13
NCBI: 238725
Homologene: 18457
Genetic Alterations
ENU-induced transitions at the following base pair locations (GRCm38):
  • A to G, chromosome 1 at 116,580,669 bp
  • T to C, chromosome 1 at 132,607,057 bp
  • T to C, chromosome 1 at 174,136,891 bp
  • C to T, chromosome 1 at 184,033,505 bp
  • T to A, chromosome 2 at 6,026,175 bp
  • A to G, chromosome 2 at 32,781,398 bp
  • A to G, chromosome 2 at 82,257,500 bp
  • T to C, chromosome 2 at 126,154,723 bp
  • A to G, chromosome 3 at 19,981,985 bp
  • A to T, chromosome 3 at 36,996,523 bp
  • G to T, chromosome 3 at 103,310,885 bp
  • T to C, chromosome 3 at 122,276,422 bp
  • C to T, chromosome 3 at 158,148,706 bp
  • G to A, chromosome 4 at 19,309,658 bp
  • T to A, chromosome 4 at 124,838,468 bp
  • T to A, chromosome 4 at 136,540,730 bp
  • A to C, chromosome 4 at 143,655,372 bp
  • T to C, chromosome 5 at 20,611,103 bp
  • G to A, chromosome 5 at 99,979,121 bp
  • T to C, chromosome 5 at 135,061,139 bp
  • G to A, chromosome 6 at 47,517,177 bp
  • G to A, chromosome 6 at 129,868,843 bp
  • T to A, chromosome 7 at 6,570,112 bp
  • G to T, chromosome 7 at 28,154,520 bp
  • C to A, chromosome 7 at 44,904,169 bp
  • T to C, chromosome 7 at 108,754,883 bp
  • A to T, chromosome 7 at 132,610,755 bp
  • A to G, chromosome 8 at 15,110,827 bp
  • G to A, chromosome 8 at 24,576,223 bp
  • T to A, chromosome 8 at 24,714,271 bp
  • A to T, chromosome 8 at 25,767,863 bp
  • C to A, chromosome 8 at 45,276,146 bp
  • T to A, chromosome 8 at 70,748,417 bp
  • A to G, chromosome 9 at 59,313,796 bp
  • A to G, chromosome 9 at 65,880,906 bp
  • T to C, chromosome 10 at 18,140,526 bp
  • C to A, chromosome 10 at 20,023,676 bp
  • G to T, chromosome 10 at 41,902,593 bp
  • A to T, chromosome 11 at 20,726,547 bp
  • A to G, chromosome 11 at 26,549,325 bp
  • C to T, chromosome 11 at 49,636,339 bp
  • A to T, chromosome 11 at 59,021,483 bp
  • T to C, chromosome 11 at 60,403,950 bp
  • C to A, chromosome 11 at 61,671,718 bp
  • T to A, chromosome 11 at 77,823,330 bp
  • T to C, chromosome 11 at 78,225,473 bp
  • G to T, chromosome 11 at 98,387,676 bp
  • A to G, chromosome 12 at 74,266,898 bp
  • G to A, chromosome 12 at 76,109,835 bp
  • G to T, chromosome 13 at 76,055,593 bp
  • A to T, chromosome 13 at 99,427,466 bp
  • G to T, chromosome 13 at 103,886,202 bp
  • A to T, chromosome 15 at 47,948,006 bp
  • A to T, chromosome 15 at 66,719,655 bp
  • A to G, chromosome 16 at 4,084,061 bp
  • G to T, chromosome 16 at 93,585,194 bp
  • A to T, chromosome 17 at 12,237,063 bp
  • T to C, chromosome 17 at 67,790,947 bp
  • A to G, chromosome 18 at 21,026,102 bp
  • T to C, chromosome 19 at 4,613,271 bp
  • A to T, chromosome 19 at 5,747,411 bp
  • G to C, chromosome 19 at 5,747,412 bp
Genotype Determination
Phenotype
G1 male heterozygous mice are viable and fertile. The G1 mice were not characterized prior to archiving.
Strain Development
C57BL/6J mice were injected with ENU, resulting in G0 mice that were bred back to C57BL/6J. Sperm was archived from G1 male mice that produced viable G2 mice.
Suggested Control Mice
Wild-type littermates or C57BL/6J mice
Donor
Bruce Beutler, M.D., University of Texas Southwestern Medical Center.
Primary Reference
MUTAGENETIX record for R1103 (G1). B. Beutler and colleagues, Center for the Genetics of Host Defense, UT Southwestern, Dallas, TX.

Colony and Husbandry Information

Colony Surveillance Program and Current Health Reports

Mice recovered from a cryo-archive will have health surveillance performed on recipient females. Health reports will be provided prior to shipment. If you require additional health status information, please email mmrrc@missouri.edu .
Coat Color
Black
MMRRC Breeding System
Random intra-strain mating
Breeding Scheme(s)
When maintaining a live colony, heterozygous mice may be bred together, bred with wild-type siblings, or bred with C57BL/6J inbred mice.
Overall Breeding Performance
Undetermined; during development, mating was done with heterozygous males; viability, fertility and other breeding statistics for heterozygous females and homozygotes are unverified, but presumably would be similar to the C57BL/6J background strain
Average litter size
Undetermined
Recommended wean age
3 weeks

Order Request Information

Limited quantities of breeder mice (recovered litter) are available from a cryoarchive; recovered litter usually available to ship in 3 to 4 months.

Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Distribution of this strain requires submission of the MMRRC Conditions of Use (COU). A link to the COU web form will be provided via email after an order has been placed; the form should be completed then or the email forwarded to your institutional official for completion.

The donor or their institution limits the distribution to non-profit institutions only.

Additional charges may apply for any special requests. Shipping costs are in addition to the basic distribution/resuscitation fees. Information on shipping costs and any additional charges will be provided by the supplying MMRRC facility.

Click button to Request this one strain. (Use the MMRRC Catalog Search to request more than one strain.)
MMRRC Item # Description Distribution Fee / Unit (US $)
*Shipping & Handling not included*
Units Notes
039176-MU-RESUS Litter recovered from cryo-archive $5,475.00 / Non-Profit Litter Recovered litter4; additional fees for any special requests.
Cryopreserved material may be available upon request, please inquire to mmrrc@missouri.edu for more information.

Some MMRRC strains were submitted by the donor as cryopreserved germplasm, and because these strains were not cryopreserved by the MMRRC, we have not assessed the quality of this material. We have extensive experience with recovery of mice from cryopreserved sperm and embryos of varying quality, including using techniques such as IVF and ICSI, and are confident that we will have success in most, if not all, cases. However, because of the unknown quality of these frozen samples, we will restrict recovery efforts to two attempts for each order. Subsequent attempts can be performed on a fee-for-service basis, in addition to the standard fees, upon request.

1 The distribution fee covers the expense of rederiving mice from a live mouse; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

2 An aliquot contains a sufficient number of embryos (in one or more vials or straws and based on the transfer success rate of the MMRRC facility) to transfer into one to three recipients. The MMRRC makes no guarantee concerning embryo transfer success experienced in the recipient investigator's laboratory. Neither gender nor genotype ratios are guaranteed.

3 An aliquot is one straw or vial with sufficient sperm to recover at least one litter of mice, as per provided protocols, when performed at the MMRRC facility. The MMRRC makes no guarantee concerning the success of these procedures when performed outside the MMRRC facilities.

4 The distribution fee covers the expense of resuscitating mice from the cryo-archive; you will receive the resulting litter. The litter will contain at minimum one mutant carrier; the actual number of animals and the gender and genotype ratios will vary. (Typically, multiple breeder pairs can be established from the recovered litter.) Prior to shipment, the MMRRC will provide information about the animals recovered. If you anticipate or find that you need to request specific genotypes, genders or quantities of mice in excess of what is likely from a resuscitated litter, you may discuss available options and pricing with the supplying MMRRC facility.

To request material from the MMRRC: Please fill out our on-line request form (accessible from the catalog search results page, or click the Request this Strain button in the fees section). If you have questions or need assistance completing this form, you may call Customer Service at (800) 910-2291 (in USA or Canada) or (530) 757-5710 (international calls). Before you call, please have with you: the MMRRC item number, quantity needed, Bill-to and Ship-to contact information.